Search for Cheap Deals on
Hotels in Panama

Photo by Susan Maycrink

Check Last Minute Panama Hotel Deals

Tonight Apr 19 - Apr 20Next weekend Apr 25 - Apr 27

Choose from 580 Panama Hotel Deals

Holiday Inn Express Hotel & Suites in North East (Erie) by IHG
Holiday Inn Express Hotel & Suites in North East (Erie) by IHG
2.5 out of 5
6310 Old Station Road, North East, PA
  • 1 hour drive from Lake Erie
The price is $118 per night from May 18 to May 19
$118
includes taxes & fees
May 18 - May 19
Book a stay at this family-friendly hotel in North East. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.8/10 Excellent! (1,001 reviews)
Quick spring break getaway
"This has been our 4-5th year in a row coming here. Perfect for the younger kids , I'd say 11-12 or younger. Breakfast is actually a Breakfast with many options. Highly recommend!"

Reviewed on Apr 15, 2025

Holiday Inn Express Hotel & Suites in North East (Erie) by IHG
La Quinta Inn & Suites by Wyndham Jamestown
La Quinta Inn & Suites by Wyndham Jamestown
2.5 out of 5
200 W 3rd St, Jamestown, NY
  • 2 hours drive from Lake Erie
The price is $89 per night from Apr 20 to Apr 21
$89
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this business-friendly hotel in Jamestown. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,002 reviews)
"I was impressed how clean everything was in our room and bathroom."

Reviewed on Apr 16, 2025

La Quinta Inn & Suites by Wyndham Jamestown
Chautauqua Harbor Hotel - Jamestown
Chautauqua Harbor Hotel - Jamestown
3.5 out of 5
10 Dunham Ave, Celoron, NY
  • 2 hours drive from Lake Erie
The price is $153 per night from Apr 20 to Apr 21
$153
includes taxes & fees
Apr 20 - Apr 21
Stay at this 3.5-star spa hotel in Celoron. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the pool and the helpful staff in our reviews. ...
9.6/10 Exceptional! (1,002 reviews)
"Love this hotel but the indoor pool is not maintained as well as it should be the cement around the pool needed to be power washed was a bit slimy and after using the hot tub I ended up with a severe rash all over my legs.."

Reviewed on Apr 12, 2025

Chautauqua Harbor Hotel - Jamestown
Peek'n Peak Resort Trademark Collection by Wyndham
Peek'n Peak Resort Trademark Collection by Wyndham
3.5 out of 5
1405 Olde Road, Clymer, NY
  • 2 hours drive from Lake Erie
The price is $136 per night from Apr 25 to Apr 26
$136
includes taxes & fees
Apr 25 - Apr 26
Stay at this 3.5-star spa resort in Clymer. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the pool and the helpful staff in our reviews. ...
8.4/10 Very Good! (884 reviews)
"We had a good time only complaint would be the guests beside us didnt care how there kids acted"

Reviewed on Apr 8, 2025

Peek'n Peak Resort Trademark Collection by Wyndham
DoubleTree by Hilton Jamestown
DoubleTree by Hilton Jamestown
4 out of 5
150 W 4th St, Jamestown, NY
  • 2 hours drive from Lake Erie
The price is $105 per night from Apr 25 to Apr 26
$105
includes taxes & fees
Apr 25 - Apr 26
Stay at this 4-star business-friendly hotel in Jamestown. Enjoy free parking, breakfast (surcharge), and room service. Our guests praise the restaurant and the ...
8.8/10 Excellent! (829 reviews)
"Great hotel! Clean, quiet, and the staff is great!"

Reviewed on Apr 16, 2025

DoubleTree by Hilton Jamestown
Days Inn by Wyndham Warren
Days Inn by Wyndham Warren
3 out of 5
210 Ludlow Street, Warren, PA
  • 3 hours drive from Lake Erie
The price is $73 per night from Apr 21 to Apr 22
$73
includes taxes & fees
Apr 21 - Apr 22
Book a stay at this business-friendly hotel in Warren. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7/10 Good! (954 reviews)
Served its purpose
"Good stay. Room was comfortable and clean. The hotel.can use some updating, but i will stay there again."

Reviewed on Apr 14, 2025

Days Inn by Wyndham Warren
Holiday Inn Express & Suites Jamestown by IHG
Holiday Inn Express & Suites Jamestown by IHG
2.5 out of 5
2811 North Main Street, Jamestown, NY
  • 2 hours drive from Lake Erie
The price is $98 per night from May 7 to May 8
$98
includes taxes & fees
May 7 - May 8
Book a stay at this business-friendly hotel in Jamestown. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (704 reviews)
"This was a great hotel! Thank you for being so friendly and engaging!"

Reviewed on Apr 17, 2025

Holiday Inn Express & Suites Jamestown by IHG
Webb's Year Round Resort
Webb's Year Round Resort
2.5 out of 5
125 W Lake Rd, Mayville, NY
  • 1 hour drive from Lake Erie
The price is $122 per night from May 19 to May 20
$122
includes taxes & fees
May 19 - May 20
Stay at this motel in Mayville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Chautauqua Institution and Chautauqua Belle Steamboat ...
7/10 Good! (99 reviews)
"They were in construction but i felt it was beautiful and cute."

Reviewed on Apr 13, 2025

Webb's Year Round Resort
Hampton Inn & Suites Jamestown
Hampton Inn & Suites Jamestown
2.5 out of 5
4 W Oak Hill Rd, Jamestown, NY
  • 2 hours drive from Lake Erie
The price is $114 per night from May 13 to May 14
$114
includes taxes & fees
May 13 - May 14
Stay at this hotel in Jamestown. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Roger ...
9/10 Wonderful! (821 reviews)
"This is a beautiful hotel and everyone was so helpful...we will stay there again this summer"

Reviewed on Apr 4, 2025

Hampton Inn & Suites Jamestown
Clarion Pointe Jamestown - Falconer
Clarion Pointe Jamestown - Falconer
2.5 out of 5
2800 North Main Street EXT, Jamestown, NY
  • 2 hours drive from Lake Erie
The price is $91 per night from Apr 21 to Apr 22
$91
includes taxes & fees
Apr 21 - Apr 22
Book a stay at this business-friendly hotel in Jamestown. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (853 reviews)
"Staff were friendly and helpful. Breakfast options fairly stndard but plentiful. Coffee was great! Only big issue was the driveway at the entrance. There were numerous potholes that were wickedly deep! Be careful driving in or you'll be in trouble!"

Reviewed on Apr 13, 2025

Clarion Pointe Jamestown - Falconer
Lakeview on the Lake
Lakeview on the Lake
2.5 out of 5
8696 East Lake Rd, Harborcreek, PA
  • 1 hour drive from Lake Erie
The price is $186 per night from Apr 21 to Apr 22
$186
includes taxes & fees
Apr 21 - Apr 22
Book a stay at this beach motel in Harborcreek. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (170 reviews)
"Great experience again! Super clean and cozy!"

Reviewed on Feb 28, 2025

Lakeview on the Lake
Quality Inn Falconer - Jamestown
Quality Inn Falconer - Jamestown
2.5 out of 5
1980 E Main Street, Falconer, NY
  • 2 hours drive from Lake Erie
The price is $86 per night from May 8 to May 9
$86
includes taxes & fees
May 8 - May 9
Book a stay at this business-friendly hotel in Falconer. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.8/10 Good! (1,000 reviews)
"I have stayed at this location many times. The rooms are always clean. The staff members are always friendly and helpful. I enjoy the breakfast bar."

Reviewed on Mar 24, 2025

Quality Inn Falconer - Jamestown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Panama

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Panama hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Panama.

Choosing the right hotel in New York has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Panama’s 580 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $73. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Panama hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Panama. No matter your reason for visiting Panama, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Panama hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Panama for as low as $73.

How many hotels are there in Panama?

With over 580 hotels in Panama, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $73.

How to find cheap car rentals in Panama?

Finding a cheap car rental deal in Panama is as easy as scoring cheap hotels in Panama. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.