Hotels Near
Puerto Santa Ana

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Featured Puerto Santa Ana Hotels

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

4.5 out of 5
Calle Numa Pompilio Llona S N, Ciudad del Rio - Puerto Santa Ana, Guayaquil, Guayas
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (1,015 reviews)
All good

Reviewed on Oct 20, 2025

Wyndham Guayaquil Puerto Santa Ana
Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE

3.5 out of 5
Puerto Santa Ana, Guayaquil, Guayas
Stay at this 3.5-star aparthotel in Guayaquil. Enjoy free WiFi, a fitness center, and parking (surcharge). Popular attractions Santa Ana Hill and Botanical Garden ...
9.2/10 Wonderful! (99 reviews)
Room was clean and nice. I certainly wouldn’t call it Luxury at least not by US standards, but it was more than adequate. The huge highlight is the location, walk out the back door of the lobby and you’re right on the River, huge number of restaurants to choose from and lots of activity. It also ...

Reviewed on Oct 29, 2025

Luxury Suites Riverfront GYE
River View suites Puerto Santa Ana gye

River View suites Puerto Santa Ana gye

3 out of 5
Puerto Santa Ana, Edificios Riverfront, Bellini, junto al hotel Wyndham., Guayaquil, Guayas
Fully refundableReserve now, pay when you stay
Stay at this 3-star apartment in Guayaquil. Enjoy free WiFi, a rooftop terrace, and a fitness center. Popular attractions Santa Ana Hill and Botanical Garden ...
8.4/10 Very Good! (39 reviews)
Owners condition that you turn the AC off when you leave and only have the auto fan on left the apartment hot all the time. The location has plenty of restaurant options and the view is nice, especially at night but it does get a little noisy on the riverfront.

Reviewed on Oct 19, 2025

River View suites Puerto Santa Ana gye
Hilton Colon Guayaquil

Hilton Colon Guayaquil

4.5 out of 5
Av Francisco de Orellana Mz 111, Guayaquil
Book a stay at this luxury hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (787 reviews)
Loved the staff and the spa was great

Reviewed on Oct 21, 2025

Hilton Colon Guayaquil
Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG

3.5 out of 5
Av. de Las Américas,junto al Aeropuerto, Intl. Jose Joaquin de Olmedo, Guayaquil, Guayas
Fully refundable
Stay at this 3.5-star business-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
9.2/10 Wonderful! (1,021 reviews)
Great hotel and staff, very friendly and accommodating.

Reviewed on Oct 29, 2025

Holiday Inn Guayaquil Airport by IHG
Oro Verde Guayaquil

Oro Verde Guayaquil

5 out of 5
9 De Octubre Y Garcia Moreno, Guayaquil, Guayas
Fully refundableReserve now, pay when you stay
Book a stay at this spa hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in our ...
9.4/10 Exceptional! (1,001 reviews)
The breakfast was amazing!

Reviewed on Oct 25, 2025

Oro Verde Guayaquil
Unipark by Oro Verde Hotels

Unipark by Oro Verde Hotels

4 out of 5
Clemente Ballén 406, entre Chile y Chimborazo, Guayaquil, Guayas
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Guayaquil. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the comfy ...
9/10 Wonderful! (1,006 reviews)
Bar was well stocked and and a cozy place to sit and see the city.

Reviewed on Oct 23, 2025

Unipark by Oro Verde Hotels
Courtyard by Marriott Guayaquil

Courtyard by Marriott Guayaquil

3.5 out of 5
Av. Francisco De Orellana #236, Guayaquil, Guayas
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star spa hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,001 reviews)
Great

Reviewed on Nov 2, 2025

Courtyard by Marriott Guayaquil
Wyndham Garden Guayaquil

Wyndham Garden Guayaquil

3.5 out of 5
Juan Tanca Marengo Ave, Abel Romero St. Plaza Del Sol, Guayaquil, Guayas
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,006 reviews)
The airport shuttle was easy to find and very efficient. The room was spacious and clean. The staff was very friendly and the breakfast was tasty!

Reviewed on Nov 2, 2025

Wyndham Garden Guayaquil
Grand Hotel Guayaquil, an Ascend Collection Hotel

Grand Hotel Guayaquil, an Ascend Collection Hotel

4 out of 5
Boyaca 1615, Guayaquil, Guayas
Fully refundableReserve now, pay when you stay
Stay at this 4-star family-friendly hotel in Guayaquil. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in ...
9/10 Wonderful! (974 reviews)
Good service and attention My experience at this hotel was very pleasant. The staff was friendly and always willing to help. Overall, I received good attention

Reviewed on Oct 29, 2025

Grand Hotel Guayaquil, an Ascend Collection Hotel
Ibis Styles El Malecon Guayaquil

Ibis Styles El Malecon Guayaquil

4 out of 5
Av Malecon Simon Bolivar, Guayaquil
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
9.4/10 Exceptional! (263 reviews)
Great price, great food and service

Reviewed on Oct 22, 2025

Ibis Styles El Malecon Guayaquil
Hotel Puerto Pacifico Guayaquil Airport

Hotel Puerto Pacifico Guayaquil Airport

4 out of 5
Av 33. Ciudadela La Garzota, Mz. 83 Solar 6-9, Guayaquil, Guayas
Fully refundableReserve now, pay when you stay
Stay at this 4-star family-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.6/10 Excellent! (216 reviews)
I didn't eat breakfast. Overall my stay was excellent. Had staff meet me at airport and take me to the hotel. Check-in was very quick. Found the room to be spacious, very clean, and the bathroom was well stocked with the shower necessities. Was very pleased with my stay and highly recommend the ...

Reviewed on Oct 18, 2025

Hotel Puerto Pacifico Guayaquil Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Puerto Santa Ana

Guayaquil is a city that has a lot going on, but you have your sights set on Puerto Santa Ana. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Puerto Santa Ana has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Puerto Santa Ana hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Guayaquil so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Puerto Santa Ana underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Puerto Santa Ana city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Puerto Santa Ana cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Puerto Santa Ana at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $68
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Puerto Santa Ana hotel you want, book it, and never look back. Because your great escape is ahead of you.