Search for Cheap Deals on
Hotels in Saint Leo

Choose from 609 Saint Leo Hotel Deals

SPOT X Hotel Tampa - Wesley Chapel by The Red Collection

SPOT X Hotel Tampa - Wesley Chapel by The Red Collection

3 out of 5
5703 Oakley Blvd Wesley Chapel FL
  • 23 min drive from Saint Leo University
Book a stay at this business-friendly hotel in Wesley Chapel. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,018 reviews)
Clean room, comfortable bed, great staff

Reviewed on Jan 27, 2026

SPOT X Hotel Tampa - Wesley Chapel by The Red Collection
Days Inn by Wyndham Brooksville/Dade City

Days Inn by Wyndham Brooksville/Dade City

2 out of 5
6320 Windmere Rd Brooksville FL
  • 31 min drive from Saint Leo University
Book a stay at this golf motel in Brooksville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in ...
7/10 Good! (1,004 reviews)
Great 👍

Reviewed on Feb 1, 2026

Days Inn by Wyndham Brooksville/Dade City
Hyatt Place Tampa/Wesley Chapel

Hyatt Place Tampa/Wesley Chapel

3 out of 5
26000 Sierra Center Boulevard Lutz FL
  • 32 min drive from Saint Leo University
Book a stay at this business-friendly hotel in Lutz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,004 reviews)
👍

Reviewed on Feb 2, 2026

Hyatt Place Tampa/Wesley Chapel
SpringHill Suites by Marriott Tampa North/I 75 Tampa Palms

SpringHill Suites by Marriott Tampa North/I 75 Tampa Palms

3 out of 5
5396 Primrose Lake Cir Tampa FL
  • 41 min drive from Saint Leo University
Book a stay at this business-friendly hotel in Tampa. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,008 reviews)
great room. nice breakfast

Reviewed on Feb 1, 2026

SpringHill Suites by Marriott Tampa North/I 75 Tampa Palms
WoodSpring Suites Wesley Chapel-Tampa

WoodSpring Suites Wesley Chapel-Tampa

2.5 out of 5
2800 Cypress Ridge Boulevard Wesley Chapel FL
  • 32 min drive from Saint Leo University
Stay at this hotel in Wesley Chapel. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.4/10 Good! (813 reviews)
Great staff, nice area, clean room

Reviewed on Jan 29, 2026

WoodSpring Suites Wesley Chapel-Tampa
Roadstar Hotel Zephyrhills

Roadstar Hotel Zephyrhills

2 out of 5
5734 Gall Blvd Zephyrhills FL
  • 20 min drive from Saint Leo University
Book a stay at this business-friendly motel in Zephyrhills. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in ...
9/10 Wonderful! (1,124 reviews)
The property is beautiful and very clean. Location is great. The staff are friendly and helpful.

Reviewed on Jan 27, 2026

Roadstar Hotel Zephyrhills
Holiday Inn Express Hotel & Suites New Tampa I-75 by IHG

Holiday Inn Express Hotel & Suites New Tampa I-75 by IHG

3.5 out of 5
8310 Galbraith Rd Tampa FL
  • 39 min drive from Saint Leo University
Book a stay at this business-friendly hotel in Tampa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9/10 Wonderful! (931 reviews)
Room was clean, friendly staff

Reviewed on Feb 1, 2026

Holiday Inn Express Hotel & Suites New Tampa I-75 by IHG
Best Western Wesley Chapel

Best Western Wesley Chapel

2.5 out of 5
5639 Oakley Blvd. Wesley Chapel FL
  • 24 min drive from Saint Leo University
Book a stay at this business-friendly hotel in Wesley Chapel. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,005 reviews)
It was convenient to everything around outside of Tampa. Friendly staff. Clean clean rooms. The breakfast attendant Lisa was very hospitable, clean, kept everything in order and very attentive to detail. Worth the stay!

Reviewed on Jan 30, 2026

Best Western Wesley Chapel
Saddlebrook Resort

Saddlebrook Resort

4 out of 5
5700 Saddlebrook Way Wesley Chapel FL
  • 21 min drive from Saint Leo University
Book a stay at this spa resort in Wesley Chapel. Enjoy free WiFi, 2 outdoor pools, and a full-service spa. Our guests praise the pool and the clean rooms in ...
7/10 Good! (10 reviews)
The rooms were newly renovated and the staff were very helpful. Very roomy

Reviewed on Jan 23, 2026

Saddlebrook Resort
Quality Inn Zephyrhills - Dade City

Quality Inn Zephyrhills - Dade City

2.5 out of 5
6815 Gall Blvd Zephyrhills FL
  • 18 min drive from Saint Leo University
Book a stay at this business-friendly hotel in Zephyrhills. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (1,002 reviews)
Front desk team are always friendly and helpful.

Reviewed on Jan 31, 2026

Quality Inn Zephyrhills - Dade City
Fairfield Inn & Suites by Marriott Tampa Wesley Chapel

Fairfield Inn & Suites by Marriott Tampa Wesley Chapel

2.5 out of 5
2650 Lajuana Blvd Wesley Chapel FL
  • 28 min drive from Saint Leo University
Book a stay at this business-friendly hotel in Wesley Chapel. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (737 reviews)
Presenting me with a complimentary bottle of water and cookie, advising of all the amenities

Reviewed on Jan 28, 2026

Fairfield Inn & Suites by Marriott Tampa Wesley Chapel
Hampton Inn & Suites Tampa-Wesley Chapel

Hampton Inn & Suites Tampa-Wesley Chapel

2.5 out of 5
2740 Cypress Ridge Blvd Wesley Chapel FL
  • 32 min drive from Saint Leo University
Book a stay at this business-friendly hotel in Wesley Chapel. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,002 reviews)
Your staff is amazing at this location

Reviewed on Feb 1, 2026

Hampton Inn & Suites Tampa-Wesley Chapel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Saint Leo

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Saint Leo hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Saint Leo.

Choosing the right hotel in Florida has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Saint Leo’s 609 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $64. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Saint Leo hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Saint Leo. No matter your reason for visiting Saint Leo, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Saint Leo hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Saint Leo for as low as $64.

How many hotels are there in Saint Leo?

With over 609 hotels in Saint Leo, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $64.

How to find cheap car rentals in Saint Leo?

Finding a cheap car rental deal in Saint Leo is as easy as scoring cheap hotels in Saint Leo. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.