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Santa Ana Vacation Packages

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Santa Ana Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
Esteban Chacon

Esteban Chacon

2 out of 5
per person
Dec 13 - Dec 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this hostel in Bocas del Toro. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Bocas del Toro Ferry Terminal and Bolivar Park are located nearby.
Hotel Vista Mar

Hotel Vista Mar

3 out of 5
per person
Dec 13 - Dec 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this 3-star hotel in Bocas del Toro. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Lil' Spa Shop by the Sea and Bolivar Park are located nearby.
Hampton by Hilton Panama

Hampton by Hilton Panama

3 out of 5
Bella Vista
per person
Dec 25 - Dec 30
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this 3-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
ataraxia bocas del toro

ataraxia bocas del toro

3.5 out of 5
per person
Dec 13 - Dec 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this 3.5-star lodge in Bastimentos. Enjoy free breakfast, free WiFi, and 3 beach bars. Popular attractions Bastimento-Bocas del Toro Ferry Terminal and Up in the Hill Organic Coffee Farm are located nearby.
El Jaguar

El Jaguar

2 out of 5
per person
Dec 13 - Dec 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this beach hostal in Bastimentos. Enjoy free WiFi, a beach locale, and a garden. Popular attractions Bastimento-Bocas del Toro Ferry Terminal and Up in the Hill Organic Coffee Farm are located nearby.
La Coralina Island House

La Coralina Island House

3.5 out of 5
per person
Dec 13 - Dec 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this 3.5-star beach hotel in Bocas del Toro. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Paunch Beach and Tortuga Beach are located nearby.
Hostel Caribbean Beach

Hostel Caribbean Beach

2 out of 5
per person
Dec 13 - Dec 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this hostal in Bocas del Toro. Enjoy free WiFi, a garden, and balconies. Popular attractions Bolivar Park and Bocas del Toro Ferry Terminal are located nearby.
Lula's Bed & Breakfast

Lula's Bed & Breakfast

3 out of 5
per person
Dec 13 - Dec 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this 3-star B&B in Bocas del Toro. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Lil' Spa Shop by the Sea and Playa El Istmito are located nearby.

3-4 Night Vacations in Santa Ana

Price found within the past 48 hours. Click for updated prices.
Casa Ancon by Wynwood House

Casa Ancon by Wynwood House

3 out of 5
per person
Dec 5 - Dec 9
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
Casa Love by Wynwood House

Casa Love by Wynwood House

2 out of 5
Casco Viejo
per person
Dec 26 - Dec 29
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
w Captivating 1BR in Casco Viejo

w Captivating 1BR in Casco Viejo

3 out of 5
El Chorrillo
per person
Dec 26 - Dec 29
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
per person
Dec 16 - Dec 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)

5-7 Night Vacations in Santa Ana

Price found within the past 48 hours. Click for updated prices.
ataraxia bocas del toro

ataraxia bocas del toro

3.5 out of 5
per person
Dec 13 - Dec 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Hotel Vista Mar

Hotel Vista Mar

3 out of 5
per person
Dec 13 - Dec 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Hampton by Hilton Panama

Hampton by Hilton Panama

3 out of 5
Bella Vista
per person
Dec 25 - Dec 30
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
Canova

Canova

3 out of 5
Calidonia
per person
Dec 23 - Dec 29
found 13 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)

Cheap Hotel Deals in Santa Ana

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
Hotel Riu Plaza Panama
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
Stay at this 4-star beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
Dreams Playa Bonita Panama - All Inclusive
Crowne Plaza Panama Airport, an IHG Hotel

Crowne Plaza Panama Airport, an IHG Hotel

4 out of 5
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
Stay at this 4-star family-friendly hotel in Tocumen. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the pool ...
Crowne Plaza Panama Airport, an IHG Hotel
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Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

3.5 out of 5
Italy Avenue, Punta Paitilla, Winston Churchill Street, Panama City, Panama
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
Plaza Paitilla Inn Hotel
Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina, Panama City, Panama
Stay at this 3-star business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean ...
Principe Hotel and Suites
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Avenida Balboa Con Multicentro, Panama City, Panama
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...
Decapolis Hotel Panama City
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica, Panama City, Panama
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff and the property condition ...
JW Marriott Panama
Novotel Panama City

Novotel Panama City

4 out of 5
Calle Jose I. Fabrega y Thais de Pons, El Cangre, Bella Vista, Panama City, Panama
Stay at this 4-star family-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
Novotel Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Copa
Tue, Nov 19 - Tue, Nov 26
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$184 Roundtrip, found 4 days ago
$184
Roundtrip
found 4 days ago
Select Copa flight, departing Tue, Nov 19 from Juan Santamaría Intl. to Tocumen Intl., returning Tue, Nov 26, priced at $184 found 4 days ago
Delta
Fri, Dec 6 - Sat, Dec 7
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$312 Roundtrip, found 14 hours ago
$312
Roundtrip
found 14 hours ago
Select Delta flight, departing Fri, Dec 6 from Fort Lauderdale - Hollywood Intl. to Tocumen Intl., returning Sat, Dec 7, priced at $312 found 14 hours ago
Delta
Fri, Nov 15 - Tue, Nov 26
MIA
Miami Intl.
PTY
Tocumen Intl.
$312 Roundtrip, found 1 day ago
$312
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Nov 15 from Miami Intl. to Tocumen Intl., returning Tue, Nov 26, priced at $312 found 1 day ago
Delta
Tue, Nov 19 - Fri, Nov 22
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$402 Roundtrip, found 1 day ago
$402
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Nov 19 from Hartsfield-Jackson Atlanta Intl. to Tocumen Intl., returning Fri, Nov 22, priced at $402 found 1 day ago

Find cheap hotels in Santa Ana

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Santa Ana hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Santa Ana.

Choosing the right hotel in Panamá Province has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Santa Ana’s 1,320 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $79. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Santa Ana hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Santa Ana. No matter your reason for visiting Santa Ana, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Santa Ana hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Santa Ana for as low as $79.

How many hotels are there in Santa Ana?

With over 1,320 hotels in Santa Ana, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $79.

How to find cheap car rentals in Santa Ana?

Finding a cheap car rental deal in Panama City is as easy as scoring cheap hotels in Santa Ana. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Santa Ana now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Santa Ana right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.