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Featured Southeast Illinois Resorts & Hotels with Spas
Holiday Inn Express Metropolis, an IHG Hotel
2179 East 5th Street, Metropolis, IL
Fully refundable
Book a stay at this business-friendly hotel in Metropolis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Country Inn & Suites by Radisson, Effingham, IL
1200 N Raney, Effingham, IL
Fully refundable
Book a stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Baymont by Wyndham Metropolis
203 E Front St, Metropolis, IL
Book a stay at this business-friendly motel in Metropolis. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. ...
Clarion Pointe Mattoon near University
206 Mcfall Rd, Mattoon, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Mattoon. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Mattoon Peterson Park and Kinzel ...
Cobblestone Hotel & Suites - Newton
100 Gregory Dr, Newton, IL
Book a stay at this business-friendly hotel in Newton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property ...
Comfort Suites Effingham
1310 W Fayette Rd, Effingham, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Comfort Suites Mattoon
1408 Broadway Ave E, Mattoon, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Mattoon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Days Inn by Wyndham Effingham
1602 Damron Court, Effingham, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Fairfield Inn & Suites Marriott Effingham
1111 North Henrietta Street, Effingham, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Holiday Inn Express & Suites Mattoon, an IHG Hotel
121 Swords Dr, Mattoon, IL
Fully refundable
Book a stay at this business-friendly hotel in Mattoon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Holiday Inn Express And Suites Effingham, an IHG Hotel
1604 West Fayette Avenue, Effingham, IL
Fully refundable
Book a stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
Quality Inn Effingham
1304 W Evergreen Drive, Effingham, IL
Fully refundableReserve now, pay when you stay
Stay at this hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options in Southeast Illinois
- Hotels with Free Parking in Southeast Illinois
- Family Hotels in Southeast Illinois
- Pet-friendly Hotels in Southeast Illinois
- Hotels with a Pool in Southeast Illinois
- Hotels with an Indoor Pool in Southeast Illinois
- Hotels with Hot Tubs in Southeast Illinois
- Luxury Hotels in Southeast Illinois
- Historic Hotels in Southeast Illinois
- Hotels with smoking rooms in Southeast Illinois
- Casinos in Southeast Illinois
Top Points of Interests in Southeast Illinois
- Hotels near Shawnee National Forest
- Hotels near Harrah's Metropolis
- Hotels near Garden of the Gods Recreation Area
- Hotels near Superman Statue
- Hotels near Lake Sara
- Hotels near Effingham Performance Center
- Hotels near Tunnel Hill State Trail
- Hotels near Sarah Bush Lincoln Hospital
- Hotels near Dixon Springs State Park
- Hotels near Cave in Rock State Park
- Hotels near World's Largest Mailbox
- Hotels near Fort Massac State Park
- Hotels near World's Largest Bird Cage
- Hotels near Lincoln Log Cabin
- Hotels near World's Largest Wind Chime
- Hotels near Vienna City Park
- Hotels near Lake Shelbyville Beach
- Hotels near World's Largest Yardstick
- Hotels near Quail Creek Country Club & Resort
- Hotels near Wabash Valley College
Cities near Southeast Illinois
- Evansville Hotels (55 mi)
- Terre Haute Hotels (80.29 mi)
- Paducah Hotels (101.18 mi)
- Effingham Hotels (42.78 mi)
- Marion Hotels (64.96 mi)
- Carbondale Hotels (74.42 mi)
- Mount Vernon Hotels (35.68 mi)
- Decatur Hotels (96.99 mi)
- Metropolis Hotels (98.03 mi)
- Mattoon Hotels (65.84 mi)
- Vincennes Hotels (42.83 mi)
- Gilbertsville Hotels (103.93 mi)
- Grand Rivers Hotels (105.47 mi)
- Southern Illinois Hotels (29.4 mi)
- Anna Hotels (89.98 mi)
- Henderson Hotels (61.53 mi)
- Makanda Hotels (79.98 mi)
- Harrisburg Hotels (56.16 mi)
- Vandalia Hotels (51.99 mi)
- Charleston Hotels (67.07 mi)
Car Rentals Near Southeast Illinois
- Car rentals in Evansville
- Car rentals in Terre Haute
- Car rentals in Paducah
- Car rentals in Effingham
- Car rentals in Marion
- Car rentals in Carbondale
- Car rentals in Mount Vernon
- Car rentals in Decatur
- Car rentals in Metropolis
- Car rentals in Mattoon
- Car rentals in Vincennes
- Car rentals in Gilbertsville
- Car rentals in Grand Rivers
- Car rentals in Southern Illinois
- Car rentals in Anna
- Car rentals in Henderson
Top Spa Resort Destinations
- Annapolis Spa Hotels
- Ottawa Valley Spa Hotels
- Tallahassee Spa Hotels
- Appalachian Mountains Spa Hotels
- Corpus Christi Spa Hotels
- Raleigh Spa Hotels
- Syracuse Spa Hotels
- Chattanooga Spa Hotels
- Grand Canyon Spa Hotels
- Toledo Spa Hotels
- Edmonton Spa Hotels
- El Paso Spa Hotels
- Omaha Spa Hotels
- Cincinnati Spa Hotels
- Fargo Spa Hotels
- Des Moines Spa Hotels
- Dayton Spa Hotels
- Flagstaff Spa Hotels
- Little Rock Spa Hotels
- Waco Spa Hotels
Top Booked Hotels in Southeast Illinois
- Best Western Delta Inn
- Country Inn & Suites by Radisson, Effingham, IL
- Harrah's Metropolis Hotel & Casino
- Comfort Suites Mattoon
- Ramada by Wyndham Effingham
- La Quinta Inn & Suites by Wyndham Effingham
- Days Inn & Suites by Wyndham Casey
- Suite Dreams Hotel
- Unique Suites Hotel
- La Quinta Inn & Suites by Wyndham Terre Haute