Search for Cheap Deals on
Luxury Hotels in Syracuse

You choose what matters — star rating, location, amenities.

We pick the perfect hotel, packed with all your must-haves.

Your hotel is revealed right after booking!


Featured Luxury Syracuse

Grand Hotel Des Ètrangers
Grand Hotel Des Ètrangers
5 out of 5
Passeggio Adorno 10/12, Syracuse
Stay at this 5-star luxury hotel in Syracuse. Enjoy free breakfast, free WiFi, and an outdoor pool. Popular attractions Tropical Aquarium of Syracuse and Spiaggetta ...
Grand Hotel Des Ètrangers
Grand Hotel Ortigia Siracusa
Grand Hotel Ortigia Siracusa
5 out of 5
Viale Mazzini, 12, Syracuse, SR
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Syracuse. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff and the property ...
Grand Hotel Ortigia Siracusa
Minareto
Minareto
5 out of 5
Via del Faro Massolivieri 26, Syracuse, SR
Stay at this 5-star luxury hotel in Syracuse. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Spiaggia del Minareto and Punta Castelluccio ...
Minareto
Eureka Palace Hotel Spa Resort
Eureka Palace Hotel Spa Resort
4 out of 5
Strada Spinagallo 50, Syracuse, SR
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa hotel in Syracuse. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
Eureka Palace Hotel Spa Resort
Algila' Ortigia Charme Hotel
Algila' Ortigia Charme Hotel
4 out of 5
Via Vittorio Veneto 93, Syracuse, SR
Fully refundableReserve now, pay when you stay
Stay at this 4-star family-friendly hotel in Syracuse. Enjoy free breakfast, free WiFi, and 2 bars/lounges. Our guests praise the breakfast and the helpful staff ...
Algila' Ortigia Charme Hotel
Hotel Livingston Siracusa
Hotel Livingston Siracusa
4 out of 5
Via Nizza, 17, Syracuse, SR
Stay at this 4-star hotel in Syracuse. Enjoy free breakfast, free WiFi, and private spa tubs. Our guests praise the helpful staff in our reviews. Popular attractions ...
Hotel Livingston Siracusa
Hotel Parco delle Fontane
Hotel Parco delle Fontane
4 out of 5
Viale Scala Greca, 325, Syracuse, SR
Fully refundableReserve now, pay when you stay
Stay at this 4-star property in Syracuse. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Rope-makers' Cave and Latomia del Paradiso are ...
Hotel Parco delle Fontane
Grande Albergo Alfeo
Grande Albergo Alfeo
4 out of 5
Via Nino Bixio 5, Syracuse, SR
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Syracuse. Enjoy free breakfast, free WiFi, and room service. Popular attractions Syracuse Forum Ruins and Santa ...
Grande Albergo Alfeo
Charme Hotel Henry's House
Charme Hotel Henry's House
4 out of 5
Via del Castello Maniace n. 68, Syracuse, SR
Fully refundableReserve now, pay when you stay
Stay at this 4-star boutique hotel in Syracuse. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular ...
Charme Hotel Henry's House
Palazzo Artemide - VRetreats
Palazzo Artemide - VRetreats
4 out of 5
Via Roma 66, Syracuse, SR
Fully refundableReserve now, pay when you stay
Stay at this 4-star hotel in Syracuse. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular ...
Palazzo Artemide - VRetreats
L'Approdo delle Sirene
L'Approdo delle Sirene
3 out of 5
Riva Giuseppe Garibaldi 15, Syracuse, SR
Stay at this 3-star business-friendly hotel in Syracuse. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff in ...
L'Approdo delle Sirene
Alla Giudecca
Alla Giudecca
3 out of 5
Via Alagona 52, Ortigia, Syracuse, SR
Fully refundableReserve now, pay when you stay
Stay at this 3-star family-friendly residence in Syracuse. Enjoy breakfast (surcharge), a business center, and an airport shuttle (surcharge). Popular attractions ...
Alla Giudecca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.