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Choose from 249 Tuscumbia Hotel Deals

The ColdWater Inn
Reviewed on Jul 12, 2025

Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals
Reviewed on Jul 13, 2025

Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites
Reviewed on Jul 10, 2025

Key West Inn
Reviewed on Jul 13, 2025

Comfort Inn & Suites Tuscumbia - Muscle Shoals
Reviewed on Jun 27, 2025

Renaissance Shoals Resort and Spa
Reviewed on Jun 29, 2025

Days Inn by Wyndham Muscle Shoals Florence
Reviewed on Jul 13, 2025

The Stricklin Hotel
Reviewed on Jul 8, 2025

Comfort Suites Florence Shoals Area
Reviewed on Jul 13, 2025

Baymont by Wyndham Florence/Muscle Shoals
Reviewed on Jul 14, 2025

Clarion Inn Sheffield Muscle Shoals
Reviewed on Jul 13, 2025

Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG
Reviewed on Jul 10, 2025
Find cheap hotels in Tuscumbia
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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Tuscumbia.
Choosing the right hotel in Alabama has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Tuscumbia’s 249 hotels. Choose the one that best catches your trip’s tourist drift.
If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $72. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Tuscumbia hotel deals at the last minute.
While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Tuscumbia. No matter your reason for visiting Tuscumbia, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.
Frequently Asked Questions About Tuscumbia hotels
Where can I find the best last-minute travel deals?
If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Tuscumbia for as low as $72.
How many hotels are there in Tuscumbia?
With over 249 hotels in Tuscumbia, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $72.
How to find cheap car rentals in Tuscumbia?
Finding a cheap car rental deal in Tuscumbia is as easy as scoring cheap hotels in Tuscumbia. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.
Top Booked Hotels in Tuscumbia
- The ColdWater Inn
- Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals
- Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites
- Key West Inn
- Comfort Inn & Suites Tuscumbia - Muscle Shoals
- Renaissance Shoals Resort and Spa
- Days Inn by Wyndham Muscle Shoals Florence
- The Stricklin Hotel
- Comfort Suites Florence Shoals Area
- Baymont by Wyndham Florence/Muscle Shoals
- Clarion Inn Sheffield Muscle Shoals
- Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG
- Residence Inn Florence Marriott
- Hampton Inn & Suites Florence-Downtown
- Hampton Inn Florence Midtown near University of North Alabama
- Hotels near Ivy Green
- Hotels near Cane Creek Canyon Nature Preserve
- Hotels near Alabama Music Hall of Fame
- Hotels near Spring Park
- Hotels near Belle Mont Mansion
- Hotels near Tuscumbia Railway Museum
- Hotels near Spring Creek Golf Course
- Hotels near Coon Dog Cemetery
- Hotels near Tennessee Valley Museum of Art
- Hotels near Tennessee River
- Hotels near University of North Alabama
- Hotels near Joe Wheeler State Park
- Hotels near Dismals Canyon
- Hotels near Tishomingo State Park
- Hotels near Shoals Golf Club
- Hotels near Red Bay Water Park
- Hotels near Fame Recording Studios
- Hotels near Renaissance Tower
- Hotels near Blackberry Trail Golf Course
- Hotels near Elk River
- Hotels with Free Parking in Tuscumbia
- Hotels with a Pool in Tuscumbia
- Historic Hotels in Tuscumbia
- Family Hotels in Tuscumbia
- Hotel Wedding Venues in Tuscumbia
- Hotels with smoking rooms in Tuscumbia
- Pet-friendly Hotels in Tuscumbia
- Hotels with Hot Tubs in Tuscumbia
- Resorts & Hotels with Spas in Tuscumbia
- Hotels with an Indoor Pool in Tuscumbia
- Luxury Hotels in Tuscumbia
- Florence Hotels
- Athens Hotels
- Muscle Shoals Hotels
- Appalachian Mountains Hotels
- Iuka Hotels
- Southeastern United States Hotels
- North Alabama Hotels
- Waterloo Hotels
- Russellville Hotels
- Killen Hotels
- Rogersville Hotels
- Phil Campbell Hotels
- Middle Tennessee Hotels
- Sheffield Hotels
- Town Creek Hotels
- Moulton Hotels
- Haleyville Hotels
- Tishomingo Hotels
- Hillsboro Hotels
- Northeast Alabama Hotels