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Hotels in Tuscumbia

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Choose from 310 Tuscumbia Hotel Deals

Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals

Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals

2 out of 5
1852 Highway 72 E Tuscumbia AL
  • 25 min drive from Cane Creek Canyon Nature Preserve
Book a stay at this business-friendly hotel in Tuscumbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,005 reviews)
"Room was clean. Not a big fan of the breakfast."

Reviewed on Jun 4, 2026

Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals
Spark by Hilton Tuscumbia Muscle Shoals

Spark by Hilton Tuscumbia Muscle Shoals

3.5 out of 5
712 Hwy 72 W Tuscumbia AL
  • 21 min drive from Cane Creek Canyon Nature Preserve
Book a stay at this business-friendly hotel in Tuscumbia. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (765 reviews)
"The breakfast was continental as stated but was hoping for eggs and meat. Also no coffee in the room. When I arrived to check-in the power was mostly out due to storms but the manager helped me get into a room and even carried my bag up three flights of steps. Great customer service from this ..."

Reviewed on Jun 4, 2026

Spark by Hilton Tuscumbia Muscle Shoals
Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites

Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites

2.5 out of 5
1934 Highway 20 Tuscumbia AL
  • 29 min drive from Cane Creek Canyon Nature Preserve
Book a stay at this business-friendly hotel in Tuscumbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (654 reviews)
"Very quick and simple overnight stay. Room was clean and comfortable. Amenities were nice. No real concerns"

Reviewed on May 30, 2026

Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites
Comfort Inn & Suites Tuscumbia - Muscle Shoals

Comfort Inn & Suites Tuscumbia - Muscle Shoals

2.5 out of 5
5101 Hwy 43 S Tuscumbia AL
  • 26 min drive from Cane Creek Canyon Nature Preserve
Book a stay at this business-friendly hotel in Tuscumbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Fame Recording Studios and Alabama ...
8.2/10 Very Good! (267 reviews)
"The front desk was never at the front desk. Felt like a ghost town. I called ahead of time and asked if the pool was opened, I was told yes. It was not. Very green. The room was damp. Any paperwork I took out was damp. I kept my socks on, they got damp, I was there for 3 nights, I received 2 towels, ..."

Reviewed on May 25, 2026

Comfort Inn & Suites Tuscumbia - Muscle Shoals
Key West Inn

Key West Inn

2 out of 5
1800 Hwy 72 West Tuscumbia AL
  • 25 min drive from Cane Creek Canyon Nature Preserve
Book a stay at this business-friendly motel in Tuscumbia. Enjoy free WiFi, free parking, and room service. Popular attractions Alabama Music Hall of Fame and ...
7/10 Good! (190 reviews)
"Room clean, respectful staff"

Reviewed on Jun 4, 2026

Key West Inn
Clarion Inn Sheffield Muscle Shoals

Clarion Inn Sheffield Muscle Shoals

2.5 out of 5
4900 Hatch Blvd Sheffield AL
  • 31 min drive from Cane Creek Canyon Nature Preserve
Book a stay at this business-friendly hotel in Sheffield. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.2/10 Good! (1,006 reviews)
"Front desk staff was super nice, both people. 6-7 grocery bags full of trash sat at the end of my hallway in the floor up against the wall for my entire 3 day stay. It was still there when I left this morning. Room was clean Shower was great. 90 degrees in the hallways of the hotel hallways."

Reviewed on Jun 3, 2026

Clarion Inn Sheffield Muscle Shoals
Renaissance Shoals Resort & Spa

Renaissance Shoals Resort & Spa

3.5 out of 5
10 Hightower Place Florence AL
  • 41 min drive from Cane Creek Canyon Nature Preserve
Book a stay at this spa resort in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (788 reviews)
"Quiet rooms, great food options, a very nice getaway."

Reviewed on May 25, 2026

Renaissance Shoals Resort & Spa
Days Inn by Wyndham Muscle Shoals Florence

Days Inn by Wyndham Muscle Shoals Florence

2 out of 5
2701 Woodward Ave Muscle Shoals AL
  • 28 min drive from Cane Creek Canyon Nature Preserve
Stay at this hotel in Muscle Shoals. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.8/10 Excellent! (1,001 reviews)
"clean room and bathroom ."

Reviewed on Jun 2, 2026

Days Inn by Wyndham Muscle Shoals Florence
The Stricklin Hotel

The Stricklin Hotel

3.5 out of 5
317 N Court St Florence AL
  • 36 min drive from Cane Creek Canyon Nature Preserve
Book a stay at this business-friendly hotel in Florence. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (870 reviews)
"Upon arrival we saw that the amenities game room bowling alley and bar were all closed for renovations. This was never mentioned anywhere when booking the hotel. You should not be charging the same price on rooms when all of your amenities are closed. The rooms have very little sound proof. The lighting ..."

Reviewed on Jun 1, 2026

The Stricklin Hotel
Comfort Suites Florence Shoals Area

Comfort Suites Florence Shoals Area

2.5 out of 5
140 Matthew Paul Ct Florence AL
  • 45 min drive from Cane Creek Canyon Nature Preserve
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (820 reviews)
"The worst coffee ever! Slamming doors and noise beyond all comprehension. No pool or hot tub, so it’s false advertisement on the Hotels.com website. Nice enough staff, but overall not worth the money and very disappointing."

Reviewed on Jun 3, 2026

Comfort Suites Florence Shoals Area
Baymont by Wyndham Florence/Muscle Shoals

Baymont by Wyndham Florence/Muscle Shoals

2.5 out of 5
115 Ana Drive Florence AL
  • 44 min drive from Cane Creek Canyon Nature Preserve
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property ...
Baymont by Wyndham Florence/Muscle Shoals
Residence Inn Florence Marriott

Residence Inn Florence Marriott

3 out of 5
1000 Sweetwater Ave Florence AL
  • 42 min drive from Cane Creek Canyon Nature Preserve
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Regency Square Mall and Children's ...
9/10 Wonderful! (353 reviews)
"The room was very large! Plenty room for family. The pool was beautiful. Also you can enjoy sitting around the firepit, there is an exercise room and also basketball area. Breakfast was excellent...It is large, alot of choices!!"

Reviewed on May 28, 2026

Residence Inn Florence Marriott
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Tuscumbia

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Frequently Asked Questions About Tuscumbia hotels

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How many hotels are there in Tuscumbia?

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