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Tuscumbia

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Tuscumbia Flights as Low as $495

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Cheap Flights to Tuscumbia

Fall in love at first flight with your vacation to Tuscumbia by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Tuscumbia on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Tuscumbia, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Tuscumbia

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Tuscumbia with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MSL airport.

What is the cheapest month to fly to Tuscumbia?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Tuscumbia are in March, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Tuscumbia?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Tuscumbia.

What airport is best to fly into Tuscumbia?

When you’re planning your trip to Tuscumbia, convenience is the name of the game. Luckily, Tuscumbia Northwest Alabama Regional Airport is nearby so you can deplane and get going on checking off everything on your Tuscumbia must-do list.

How much are flights to Tuscumbia?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Tuscumbia on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $495, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Tuscumbia?

The trick to saving a stack of cash on your flight to Tuscumbia? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $495 right now, why wait?

Tuscumbia Flight Information
Destination airport
Northwest Alabama Regional
Destination airport IATA code
MSL
Roundtrip price
$495

Last Minute Hotel Deals in Tuscumbia

The ColdWater Inn

The ColdWater Inn

3.5 out of 5
712 Hwy 72 W Tuscumbia AL
Book a stay at this business-friendly hotel in Tuscumbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (678 reviews)
Great staff

Reviewed on Jan 18, 2026

The ColdWater Inn
Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites

Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites

2.5 out of 5
1934 Highway 20 Tuscumbia AL
Book a stay at this business-friendly hotel in Tuscumbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (631 reviews)
The staff was excellent! The front desk clerk even remembered my name. Super nice hotel.

Reviewed on Jan 20, 2026

Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites
Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals

Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals

2 out of 5
1852 Highway 72 E Tuscumbia AL
Book a stay at this business-friendly hotel in Tuscumbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (1,000 reviews)
Yes had no problems

Reviewed on Dec 29, 2025

Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals
Comfort Inn & Suites Tuscumbia - Muscle Shoals

Comfort Inn & Suites Tuscumbia - Muscle Shoals

2.5 out of 5
5101 Hwy 43 S Tuscumbia AL
Book a stay at this business-friendly hotel in Tuscumbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Alabama Music Hall of Fame and ...
8.2/10 Very Good! (251 reviews)
Yes

Reviewed on Dec 15, 2025

Comfort Inn & Suites Tuscumbia - Muscle Shoals
Key West Inn

Key West Inn

2 out of 5
1800 Hwy 72 West Tuscumbia AL
Book a stay at this business-friendly motel in Tuscumbia. Enjoy free WiFi, free parking, and room service. Popular attractions Alabama Music Hall of Fame and ...
6.8/10 (183 reviews)
One night - clean; comfortable.

Reviewed on Oct 12, 2025

Key West Inn
The Stricklin Hotel

The Stricklin Hotel

3.5 out of 5
317 N Court St Florence AL
Book a stay at this business-friendly hotel in Florence. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (815 reviews)
Nice staff clean. Might want to bring ear plugs as you can hear people in halls and neighboring rooms.

Reviewed on Jan 19, 2026

The Stricklin Hotel
Days Inn by Wyndham Muscle Shoals Florence

Days Inn by Wyndham Muscle Shoals Florence

2 out of 5
2701 Woodward Ave Muscle Shoals AL
Stay at this hotel in Muscle Shoals. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.4/10 Very Good! (1,000 reviews)
M

Reviewed on Jan 16, 2026

Days Inn by Wyndham Muscle Shoals Florence
Clarion Inn Sheffield Muscle Shoals

Clarion Inn Sheffield Muscle Shoals

2.5 out of 5
4900 Hatch Blvd Sheffield AL
Book a stay at this business-friendly hotel in Sheffield. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.2/10 Good! (972 reviews)
The room was clean bed was comfortable and the staff was friendly and helpful.

Reviewed on Jan 19, 2026

Clarion Inn Sheffield Muscle Shoals
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.