Hotels Near
Uptown Greenville

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Featured Uptown Greenville Hotels

Microtel Inn & Suites by Wyndham Greenville/University Medic
Microtel Inn & Suites by Wyndham Greenville/University Medic
2 out of 5
450 Moye Blvd, Greenville, NC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.2/10 Good! (1,001 reviews)
"It's in a good location"

Reviewed on Jan 6, 2025

Microtel Inn & Suites by Wyndham Greenville/University Medic
Holiday Inn Greenville, an IHG Hotel
Holiday Inn Greenville, an IHG Hotel
3 out of 5
203 Greenville Blvd SW, Greenville, NC
Fully refundable
Stay at this 3-star business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,000 reviews)
"Overall stay was great, close to shopping and restaurants. Everything was neat and clean. Desk attendants were polite and friendly."

Reviewed on Dec 29, 2024

Holiday Inn Greenville, an IHG Hotel
Best Western Plus Suites-Greenville
Best Western Plus Suites-Greenville
2.5 out of 5
2310 Greenville Boulevard NE, Greenville, NC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,000 reviews)
"Good for a quick night overnight, dog friendly. Clean. Quiet."

Reviewed on Jan 5, 2025

Best Western Plus Suites-Greenville
Quality Inn Greenville near University
Quality Inn Greenville near University
2.5 out of 5
821 Memorial Dr, Greenville, NC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (885 reviews)
"I loved the waffles served during the continental breakfast. The gym was nice as well. I went usually after 10pm and had the gym to myself. The staff was very friendly and helpful. It’s directly across the street from dollar tree and Denny’s which was very convenient."

Reviewed on Dec 30, 2024

Quality Inn Greenville near University
Country Inn & Suites by Radisson, Greenville, NC
Country Inn & Suites by Radisson, Greenville, NC
3 out of 5
3900 S Memorial Dr, Winterville, NC
Fully refundable
Stay at this 3-star business-friendly hotel in Winterville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.4/10 Good! (662 reviews)
"Clean."

Reviewed on Dec 14, 2024

Country Inn & Suites by Radisson, Greenville, NC
Homewood Suites By Hilton Greenville, NC
Homewood Suites By Hilton Greenville, NC
3 out of 5
420 Moye Blvd, Greenville, NC
Fully refundableReserve now, pay when you stay
Stay at this 3-star golf hotel in Greenville. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (185 reviews)
"The property, in all ways, was bright and inviting. The staff was very friendly. The breakfast area was very large, nice and clean."

Reviewed on Jan 2, 2025

Homewood Suites By Hilton Greenville, NC
Holiday Inn Express Greenville, an IHG Hotel
Holiday Inn Express Greenville, an IHG Hotel
2.5 out of 5
909 Moye Blvd, Greenville, NC
Fully refundable
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free parking, and a free airport shuttle. Our guests praise the breakfast and ...
8.4/10 Very Good! (862 reviews)
"All good"

Reviewed on Dec 13, 2024

Holiday Inn Express Greenville, an IHG Hotel
Residence Inn by Marriott Greenville
Residence Inn by Marriott Greenville
3 out of 5
1820 W 5th St, Greenville, NC
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (369 reviews)
"Almost a perfect stay! Coffee pot missing from room and an iron in poker condition. Appliances should be checked during the cleaning process."

Reviewed on Dec 15, 2024

Residence Inn by Marriott Greenville
Super 8 by Wyndham Greenville
Super 8 by Wyndham Greenville
2 out of 5
1004 South Memorial Drive, Greenville, NC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly motel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
6.4/10 (543 reviews)
"Fine"

Reviewed on Oct 1, 2024

Super 8 by Wyndham Greenville
Comfort Inn & Suites Greenville Near Convention Center
Comfort Inn & Suites Greenville Near Convention Center
2.5 out of 5
3212 S Memorial Dr, Greenville, NC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (255 reviews)
"Clean and quiet. Staff was very courteous."

Reviewed on Dec 17, 2024

Comfort Inn & Suites Greenville Near Convention Center
Baymont by Wyndham Greenville
Baymont by Wyndham Greenville
2.5 out of 5
3439 S Memorial Drive, Greenville, NC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
6.2/10 (1,000 reviews)
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Reviewed on Dec 14, 2024

Baymont by Wyndham Greenville
Fairfield Inn and Suites by Marriott Washington
Fairfield Inn and Suites by Marriott Washington
2.5 out of 5
2090 West 15th Street, Washington, NC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Washington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (524 reviews)
5 out of 5 stars
"My trip was aimed to get away from stress and relax. I achieved both at my stay here. The staff was friendly, the hotel still festive and decorative with Christmas, and the room quiet and cozy! I felt very comfortable here. Definitely would go back and do it all over again."

Reviewed on Jan 3, 2025

Fairfield Inn and Suites by Marriott Washington
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Uptown Greenville

Greenville is a city that has a lot going on, but you have your sights set on Uptown Greenville. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Uptown Greenville has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Uptown Greenville hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Greenville so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Uptown Greenville underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Uptown Greenville city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Uptown Greenville cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Uptown Greenville at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $77
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Uptown Greenville hotel you want, book it, and never look back. Because your great escape is ahead of you.