Search for Cheap Deals on
Hotels in Central

Photo by Ryan Watts

Choose from 1490 Central Hotel Deals

The Shepherd Hotel Downtown Clemson
The Shepherd Hotel Downtown Clemson
4 out of 5
110 Sloan St, Clemson, SC
  • 15 min drive from Southern Wesleyan University
The price is $199 per night from Jan 26 to Jan 27
$199
includes taxes & fees
Jan 26 - Jan 27
Stay at this 4-star hotel in Clemson. Enjoy free WiFi, breakfast (surcharge), and valet parking (surcharge). Our guests praise the helpful staff and the clean ...
9.6/10 Exceptional! (457 reviews)
"Great place"

Reviewed on Jan 18, 2025

The Shepherd Hotel Downtown Clemson
Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference Center
2.5 out of 5
1310 Tiger Blvd, Clemson, SC
  • 13 min drive from Southern Wesleyan University
The price is $103 per night from Jan 27 to Jan 28
$103
includes taxes & fees
Jan 27 - Jan 28
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (985 reviews)
"Loved having Nick and Mikes nearby for dinner."

Reviewed on Jan 20, 2025

Best Western Plus Clemson Hotel & Conference Center
Lakeside Lodge Clemson
Lakeside Lodge Clemson
2.5 out of 5
13500 Clemson Blvd, Seneca, SC
  • 18 min drive from Southern Wesleyan University
The price is $134 per night from Jan 24 to Jan 25
$134
includes taxes & fees
Jan 24 - Jan 25
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8.8/10 Excellent! (773 reviews)
"Very comfortable"

Reviewed on Jan 18, 2025

Lakeside Lodge Clemson
Inn @ Clemson
Inn @ Clemson
2.5 out of 5
1303 Tiger Blvd, Clemson, SC
  • 13 min drive from Southern Wesleyan University
The price is $99 per night from Jan 26 to Jan 27
$99
includes taxes & fees
Jan 26 - Jan 27
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (1,001 reviews)
"I liked the location, as it was convenient to my work. Also, I found the hotel to be very clean and the staff friendly."

Reviewed on Jan 21, 2025

Inn @ Clemson
Comfort Inn & Suites Clemson - University Area
Comfort Inn & Suites Clemson - University Area
2.5 out of 5
1305 Tiger Blvd, Clemson, SC
  • 13 min drive from Southern Wesleyan University
The price is $103 per night from Jan 29 to Jan 30
$103
includes taxes & fees
Jan 29 - Jan 30
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,001 reviews)
"Clean. Wifi wasnt great."

Reviewed on Jan 19, 2025

Comfort Inn & Suites Clemson - University Area
The Abernathy of Clemson
The Abernathy of Clemson
4 out of 5
157 Old Greenville Hwy, Clemson, SC
  • 16 min drive from Southern Wesleyan University
The price is $176 per night from Jan 26 to Jan 27
$176
includes taxes & fees
Jan 26 - Jan 27
Stay at this 4-star business-friendly hotel in Clemson. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
9.6/10 Exceptional! (485 reviews)
"Great place to stay on campus! Immaculate and surprisingly very quiet."

Reviewed on Jan 15, 2025

The Abernathy of Clemson
Holiday Inn Express & Suites Clemson, an IHG Hotel
Holiday Inn Express & Suites Clemson, an IHG Hotel
2.5 out of 5
1381 Tiger Blvd, Clemson, SC
  • 12 min drive from Southern Wesleyan University
The price is $125 per night from Jan 29 to Jan 30
$125
includes taxes & fees
Jan 29 - Jan 30
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (849 reviews)
"Hotel was very clean. Staff extremely friendly and helpful. Would definitely stay again."

Reviewed on Jan 13, 2025

Holiday Inn Express & Suites Clemson, an IHG Hotel
Microtel Inn & Suites by Wyndham Anderson/Clemson
Microtel Inn & Suites by Wyndham Anderson/Clemson
2 out of 5
102 Electric City Blvd, Anderson, SC
  • 26 min drive from Southern Wesleyan University
The price is $101 per night from Feb 4 to Feb 5
$101
includes taxes & fees
Feb 4 - Feb 5
Book a stay at this business-friendly hotel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (1,000 reviews)
"Always good hotel for visits to this area!"

Reviewed on Jan 20, 2025

Microtel Inn & Suites by Wyndham Anderson/Clemson
The Inn at Patrick Square
The Inn at Patrick Square
3.5 out of 5
115 Market Street, Clemson, SC
  • 8 min drive from Southern Wesleyan University
The price is $176 per night from Jan 26 to Jan 27
$176
includes taxes & fees
Jan 26 - Jan 27
Stay at this 3.5-star hotel in Clemson. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
9.8/10 Exceptional! (675 reviews)
"Staff was awesome"

Reviewed on Dec 30, 2024

The Inn at Patrick Square
Tru by Hilton Seneca Clemson
Tru by Hilton Seneca Clemson
2.5 out of 5
13050 Clemson Blvd, Seneca, SC
  • 18 min drive from Southern Wesleyan University
The price is $127 per night from Jan 29 to Jan 30
$127
includes taxes & fees
Jan 29 - Jan 30
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (666 reviews)
"2nd time staying here. Was just as wonderful as the my first stay. Staff was great!"

Reviewed on Jan 20, 2025

Tru by Hilton Seneca Clemson
Holiday Inn Express Hotel & Suites Anderson-I-85, an IHG Hotel
Holiday Inn Express Hotel & Suites Anderson-I-85, an IHG Hotel
2.5 out of 5
107 Interstate Blvd, Anderson, SC
  • 27 min drive from Southern Wesleyan University
The price is $110 per night from Jan 26 to Jan 27
$110
includes taxes & fees
Jan 26 - Jan 27
Book a stay at this business-friendly hotel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (504 reviews)
"The staff was very polite. Rooms were up to date."

Reviewed on Jan 19, 2025

Holiday Inn Express Hotel & Suites Anderson-I-85, an IHG Hotel
Comfort Suites Greenville South
Comfort Suites Greenville South
2.5 out of 5
10 Kalyns Way, Piedmont, SC
  • 49 min drive from Southern Wesleyan University
The price is $122 per night from Feb 19 to Feb 20
$122
includes taxes & fees
Feb 19 - Feb 20
Book a stay at this business-friendly hotel in Piedmont. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (811 reviews)
"No. Coffee in the lobby!!!!!!"

Reviewed on Jan 21, 2025

Comfort Suites Greenville South
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Central

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Central hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Central.

Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Central’s 1,490 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $99. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Central hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Central. No matter your reason for visiting Central, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Central hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Central for as low as $99.

How many hotels are there in Central?

With over 1,490 hotels in Central, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $99.

How to find cheap car rentals in Central?

Finding a cheap car rental deal in Central is as easy as scoring cheap hotels in Central. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.