Search for Cheap Deals on
Hotels in Central

Choose from 1671 Central Hotel Deals

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd Clemson SC
  • 13 min drive from Southern Wesleyan University
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,000 reviews)
Everything was nice

Reviewed on Mar 24, 2026

Best Western Plus Clemson Hotel & Conference Center
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

2 out of 5
299 Outpost Rd Seneca SC
  • 36 min drive from Southern Wesleyan University
Stay at this cabin in Seneca. Enjoy free parking, patios, and climate control. Popular attractions Friendship Recreaction Area and Cross Creek Plantation Golf ...
9.8/10 Exceptional! (66 reviews)
I bought things like plates, towels,

Reviewed on Mar 8, 2026

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

4 out of 5
110 Sloan St Clemson SC
  • 15 min drive from Southern Wesleyan University
Stay at this hotel in Clemson. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. ...
9.8/10 Exceptional! (774 reviews)
Great

Reviewed on Mar 24, 2026

The Shepherd Hotel Downtown Clemson
Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd Seneca SC
  • 18 min drive from Southern Wesleyan University
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
9/10 Wonderful! (1,002 reviews)
The unit was terrific. Quiet and clean. only issue is daily train whistle nearby. Nice area with grrat restaurant in hotel.

Reviewed on Mar 21, 2026

Lakeside Lodge Clemson
Inn @ Clemson

Inn @ Clemson

2.5 out of 5
1303 Tiger Blvd Clemson SC
  • 13 min drive from Southern Wesleyan University
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,002 reviews)
I am glad I only paid $77 for the night. Unfortunately the place was what I expected for a football hotel. Was hoping to be surprised. Run down. Old. Dated. Worn carpet, stained worn chair. Shower looked clean, but caulking needed replaced. And someone glued knobs on shower door to open?? The bedding ...

Reviewed on Mar 25, 2026

Inn @ Clemson
Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

2 out of 5
1007 George Smith Mill Rd Anderson SC
  • 28 min drive from Southern Wesleyan University
Book a stay at this business-friendly motel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (1,013 reviews)
I love staying at this location.always great. Trinity,sherry, Jennifer and same are awesome . They also have a wonderful housekeeping crew.

Reviewed on Mar 25, 2026

Days Inn by Wyndham Anderson
Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn

3 out of 5
240 Madren Center Drive Clemson SC
  • 17 min drive from Southern Wesleyan University
Book a stay at this golf hotel in Clemson. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our ...
9.4/10 Exceptional! (987 reviews)
Linens were scratchy and mold growing in showers

Reviewed on Mar 22, 2026

Clemson University's James F. Martin Inn
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

2.5 out of 5
1305 Tiger Blvd Clemson SC
  • 13 min drive from Southern Wesleyan University
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,001 reviews)
Nice large room woth comfortable bed. Toilet paper was thin. Nice large television. Breakfast was good. Liked that that they changed it slightly each day.

Reviewed on Mar 22, 2026

Comfort Inn & Suites Clemson - University Area
The Inn at Patrick Square

The Inn at Patrick Square

3.5 out of 5
115 Market Street Clemson SC
  • 8 min drive from Southern Wesleyan University
Book a stay at this business-friendly hotel in Clemson. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the helpful staff and ...
9.8/10 Exceptional! (813 reviews)
Beautiful hotel. We had a short stay when in town for a college tour. Less than 10 minute drive the the campus. Very clean. Friendly staff.

Reviewed on Mar 21, 2026

The Inn at Patrick Square
Horizon Inn & Suites

Horizon Inn & Suites

2 out of 5
3025 N Main Street Anderson SC
  • 36 min drive from Southern Wesleyan University
Stay at this hotel in Anderson. Enjoy free WiFi, free parking, and a fitness center. Popular attractions Anderson Mall and North Anderson Park are located ...
4.8/10 (278 reviews)
Upon pulling into the property, we were greeted by a woman walking around the front door weilding a hatchet, screaming about the lady up front owing her money she wanted back. She was kind enough to grant us entry to the establishment. Upon reaching the check-in counter we met the recipient of the ...

Reviewed on Mar 19, 2026

Horizon Inn & Suites
Quality Inn & Suites Easley - Greenville

Quality Inn & Suites Easley - Greenville

2.5 out of 5
5539 Calhoun Memorial Hwy Easley SC
  • 36 min drive from Southern Wesleyan University
Stay at this hotel in Easley. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Dollar Tree Plaza and Easley Creek Plaza are located ...
7/10 Good! (414 reviews)
Quick check in process. Breakfast included was nice and the usual grab and go items and also make your own waffle along with eggs and sausage links. Pretty good. Room was standard and bed was comfortable. It was a good option for a quick overnight stay. No issues.

Reviewed on Mar 15, 2026

Quality Inn & Suites Easley - Greenville
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

2.5 out of 5
1011 East North 1st Street Seneca SC
  • 30 min drive from Southern Wesleyan University
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (686 reviews)
Rooms good for the night. No issues with rooms

Reviewed on Mar 9, 2026

Hampton Inn & Suites Seneca-Clemson Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Central

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Central hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Central.

Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Central’s 1,671 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $58. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Central hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Central. No matter your reason for visiting Central, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Central hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Central for as low as $58.

How many hotels are there in Central?

With over 1,671 hotels in Central, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $58.

How to find cheap car rentals in Central?

Finding a cheap car rental deal in Central is as easy as scoring cheap hotels in Central. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.