Search Cheap Flights to
Jefferson

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Jefferson Flights as Low as $108

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Allegiant Air
Mon, Nov 16 - Mon, Nov 23
PIE
St. Petersburg-Clearwater Intl.
TRI
Tri-Cities Regional
$108 Roundtrip, found 3 hours ago
$108
Roundtrip
found 3 hours ago
Select Allegiant Air flight, departing Mon, Nov 16 from St. Petersburg-Clearwater Intl. to Tri-Cities Regional, returning Mon, Nov 23, priced at $108 found 3 hours ago
Allegiant Air
Wed, Dec 23 - Tue, Dec 29
FLL
Fort Lauderdale - Hollywood Intl.
AVL
Asheville Regional
$122 Roundtrip, found 2 hours ago
$122
Roundtrip
found 2 hours ago
Select Allegiant Air flight, departing Wed, Dec 23 from Fort Lauderdale - Hollywood Intl. to Asheville Regional, returning Tue, Dec 29, priced at $122 found 2 hours ago
Breeze Airways
Mon, Nov 23 - Fri, Nov 27
IAD
Washington Dulles Intl.
TRI
Tri-Cities Regional
$165 Roundtrip, found 14 hours ago
$165
Roundtrip
found 14 hours ago
Select Breeze Airways flight, departing Mon, Nov 23 from Washington Dulles Intl. to Tri-Cities Regional, returning Fri, Nov 27, priced at $165 found 14 hours ago
Allegiant Air
Thu, Dec 3 - Tue, Dec 15
EWR
Newark Liberty Intl. Airport
AVL
Asheville Regional
$169 Roundtrip, just found
$169
Roundtrip
just found
Select Allegiant Air flight, departing Thu, Dec 3 from Newark Liberty Intl. Airport to Asheville Regional, returning Tue, Dec 15, priced at $169 just found
Breeze Airways
Fri, Nov 20 - Mon, Nov 23
MCO
Orlando Intl.
TRI
Tri-Cities Regional
$173 Roundtrip, found 2 hours ago
$173
Roundtrip
found 2 hours ago
Select Breeze Airways flight, departing Fri, Nov 20 from Orlando Intl. to Tri-Cities Regional, returning Mon, Nov 23, priced at $173 found 2 hours ago
American Airlines
Tue, Jan 5 - Fri, Jan 22
LGA
LaGuardia
AVL
Asheville Regional
$209 Roundtrip, just found
$209
Roundtrip
just found
Select American Airlines flight, departing Tue, Jan 5 from LaGuardia to Asheville Regional, returning Fri, Jan 22, priced at $209 just found
Allegiant Air
Wed, Dec 23 - Sun, Dec 27
PIE
St. Petersburg-Clearwater Intl.
AVL
Asheville Regional
$220 Roundtrip, found 1 day ago
$220
Roundtrip
found 1 day ago
Select Allegiant Air flight, departing Wed, Dec 23 from St. Petersburg-Clearwater Intl. to Asheville Regional, returning Sun, Dec 27, priced at $220 found 1 day ago
Bargain Flight
Tue, Dec 8 - Sat, Dec 12
LAS
Harry Reid Intl.
AVL
Asheville Regional
$327 Roundtrip, found 4 days ago
$327
Roundtrip
found 4 days ago
Select Bargain Flight flight, departing Tue, Dec 8 from Harry Reid Intl. to Asheville Regional, returning Sat, Dec 12, priced at $327 found 4 days ago
American Airlines
Tue, Apr 13 - Sat, Apr 17
MCO
Orlando Intl.
AVL
Asheville Regional
$329 Roundtrip, found 8 hours ago
$329
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Tue, Apr 13 from Orlando Intl. to Asheville Regional, returning Sat, Apr 17, priced at $329 found 8 hours ago
Delta
Sat, Dec 12 - Wed, Jan 6
IAH
George Bush Intercontinental
TRI
Tri-Cities Regional
$331 Roundtrip, found 18 hours ago
$331
Roundtrip
found 18 hours ago
Select Delta flight, departing Sat, Dec 12 from George Bush Intercontinental to Tri-Cities Regional, returning Wed, Jan 6, priced at $331 found 18 hours ago
Delta
Tue, Jan 26 - Tue, Feb 16
EWR
Newark Liberty Intl. Airport
TRI
Tri-Cities Regional
$341 Roundtrip, found 17 hours ago
$341
Roundtrip
found 17 hours ago
Select Delta flight, departing Tue, Jan 26 from Newark Liberty Intl. Airport to Tri-Cities Regional, returning Tue, Feb 16, priced at $341 found 17 hours ago
American Airlines
Tue, Dec 1 - Wed, Dec 16
IAH
George Bush Intercontinental
AVL
Asheville Regional
$349 Roundtrip, found 3 hours ago
$349
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Tue, Dec 1 from George Bush Intercontinental to Asheville Regional, returning Wed, Dec 16, priced at $349 found 3 hours ago
Delta
Mon, Feb 1 - Mon, Feb 8
FLL
Fort Lauderdale - Hollywood Intl.
TRI
Tri-Cities Regional
$355 Roundtrip, found 20 hours ago
$355
Roundtrip
found 20 hours ago
Select Delta flight, departing Mon, Feb 1 from Fort Lauderdale - Hollywood Intl. to Tri-Cities Regional, returning Mon, Feb 8, priced at $355 found 20 hours ago
American Airlines
Tue, May 4 - Tue, May 11
LGA
LaGuardia
TRI
Tri-Cities Regional
$369 Roundtrip, found 3 days ago
$369
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, May 4 from LaGuardia to Tri-Cities Regional, returning Tue, May 11, priced at $369 found 3 days ago
Delta
Thu, Nov 26 - Wed, Dec 2
DTW
Detroit Metropolitan Wayne County
TRI
Tri-Cities Regional
$372 Roundtrip, found 20 hours ago
$372
Roundtrip
found 20 hours ago
Select Delta flight, departing Thu, Nov 26 from Detroit Metropolitan Wayne County to Tri-Cities Regional, returning Wed, Dec 2, priced at $372 found 20 hours ago
Delta
Mon, Dec 14 - Fri, Dec 25
JFK
John F. Kennedy Intl.
TRI
Tri-Cities Regional
$376 Roundtrip, found 17 hours ago
$376
Roundtrip
found 17 hours ago
Select Delta flight, departing Mon, Dec 14 from John F. Kennedy Intl. to Tri-Cities Regional, returning Fri, Dec 25, priced at $376 found 17 hours ago

Cheap Flights to Jefferson

Fall in love at first flight with your vacation to Jefferson by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Jefferson on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Jefferson, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Jefferson

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Jefferson with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the TRI airport.

What is the cheapest month to fly to Jefferson?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Jefferson are in November, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Jefferson?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to Jefferson.

What airport is best to fly into Jefferson?

When you’re planning your trip to Jefferson, convenience is the name of the game. Luckily, Jefferson Tri-Cities Regional Airport is nearby so you can deplane and get going on checking off everything on your Jefferson must-do list.

How much are flights to Jefferson?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Jefferson on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $108, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Jefferson?

The trick to saving a stack of cash on your flight to Jefferson? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $108 right now, why wait?

Jefferson Flight Information
Destination airport
Tri-Cities Regional
Destination airport IATA code
TRI
Roundtrip price
$108

Last Minute Hotel Deals in Jefferson

La Quinta Inn & Suites by Wyndham Boone University

La Quinta Inn & Suites by Wyndham Boone University

3 out of 5
165 Highway 105 Extension Boone NC
Book a stay at this business-friendly hotel in Boone. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,262 reviews)
"La quinta had a fire unexpectedly the day we were to stay there. They switched us to a sister hotel for the night. The graystone lodge was excellent and switch was seamless. La quinta did speak of us getting a discount on our night due to the change and frustration with change. That was not given ..."

Reviewed on Nov 12, 2026

Get rates
La Quinta Inn & Suites by Wyndham Boone University
Graystone Lodge, an Ascend Collection Hotel

Graystone Lodge, an Ascend Collection Hotel

3 out of 5
2419 NC HWY 105 South Boone NC
Book a stay at this business-friendly hotel in Boone. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
9.4/10 Exceptional! (1,366 reviews)
"Property is well situated off of the extremely busy HWY 105 so be careful getting in and out of the parking lot. Staff was very friendly and helpful with a smooth checkin. Room is on the smaller side but was clean except for a few specks of dust from what I think was the ac unit located directly ..."

Reviewed on Nov 12, 2026

Get rates
Graystone Lodge, an Ascend Collection Hotel
Rhode's Motor Lodge

Rhode's Motor Lodge

2 out of 5
1377 Blowing Rock Road Boone NC
Stay at this hotel in Boone. Enjoy free WiFi, free parking, and a fireplace in the lobby. Our guests praise the restaurant and the helpful staff in our reviews. ...
Get rates
Rhode's Motor Lodge
Comfort Suites Boone - University Area

Comfort Suites Boone - University Area

2.5 out of 5
1184 Highway 105 Boone NC
Stay at this hotel in Boone. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions ...
Get rates
Comfort Suites Boone - University Area
Fairfield Inn by Marriott Boone

Fairfield Inn by Marriott Boone

3 out of 5
2060 Blowing Rock Rd Boone NC
Book a stay at this business-friendly hotel in Boone. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Get rates
Fairfield Inn by Marriott Boone
Holiday Inn Boone - University Area by IHG

Holiday Inn Boone - University Area by IHG

3 out of 5
1075 Highway 105 Boone NC
Book a stay at this business-friendly hotel in Boone. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
8/10 Very Good! (943 reviews)
"The location and staff were excellent! They just need to make sure that they maids are adequately cleaning the rooms and such. The heater was loud when it would come on as well, and the bathrooms had water pressure issues/toilet wise. Other than that, it's a nice place to stay, and Boone is always ..."

Reviewed on Nov 8, 2026

Get rates
Holiday Inn Boone - University Area by IHG
Country Inn & Suites by Radisson, Boone, NC

Country Inn & Suites by Radisson, Boone, NC

3 out of 5
818 E King St Boone NC
Book a stay at this business-friendly hotel in Boone. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Get rates
Country Inn & Suites by Radisson, Boone, NC
TownePlace Suites by Marriott Boone

TownePlace Suites by Marriott Boone

3 out of 5
1110 Meadowview Dr, Boone, NC 28607 Boone NC
Stay at this hotel in Boone. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Appalachian ...
Get rates
TownePlace Suites by Marriott Boone
See all 1,803 properties in Jefferson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.