Search Cheap Flights to
Sanford

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Sanford Flights as Low as $160

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Wed, Apr 2 - Wed, Apr 16
RDU
Raleigh - Durham Intl.
PWM
Portland Intl. Jetport
$160 Roundtrip, found 3 days ago
$160
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Wed, Apr 2 from Raleigh - Durham Intl. to Portland Intl. Jetport, returning Wed, Apr 16, priced at $160 found 3 days ago
Frontier Airlines
Wed, Apr 2 - Mon, Apr 14
RDU
Raleigh - Durham Intl.
PWM
Portland Intl. Jetport
$170 Roundtrip, found 3 days ago
$170
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Wed, Apr 2 from Raleigh - Durham Intl. to Portland Intl. Jetport, returning Mon, Apr 14, priced at $170 found 3 days ago
United
Mon, May 5 - Wed, May 7
EWR
Newark Liberty Intl. Airport
PWM
Portland Intl. Jetport
$180 Roundtrip, found 1 day ago
$180
Roundtrip
found 1 day ago
Select United flight, departing Mon, May 5 from Newark Liberty Intl. Airport to Portland Intl. Jetport, returning Wed, May 7, priced at $180 found 1 day ago
JetBlue Airways
Wed, Apr 2 - Tue, Apr 15
RDU
Raleigh - Durham Intl.
PWM
Portland Intl. Jetport
$181 Roundtrip, found 3 days ago
$181
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Wed, Apr 2 from Raleigh - Durham Intl. to Portland Intl. Jetport, returning Tue, Apr 15, priced at $181 found 3 days ago
Delta
Sat, Apr 19 - Tue, Apr 29
RSW
Southwest Florida Intl.
PWM
Portland Intl. Jetport
$189 Roundtrip, found 1 day ago
$189
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Apr 19 from Southwest Florida Intl. to Portland Intl. Jetport, returning Tue, Apr 29, priced at $189 found 1 day ago
United
Mon, May 5 - Wed, May 7
EWR
Newark Liberty Intl. Airport
PWM
Portland Intl. Jetport
$190 Roundtrip, found 1 day ago
$190
Roundtrip
found 1 day ago
Select United flight, departing Mon, May 5 from Newark Liberty Intl. Airport to Portland Intl. Jetport, returning Wed, May 7, priced at $190 found 1 day ago
Frontier Airlines
Sat, Apr 5 - Sun, Apr 13
RDU
Raleigh - Durham Intl.
PWM
Portland Intl. Jetport
$200 Roundtrip, found 3 days ago
$200
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Sat, Apr 5 from Raleigh - Durham Intl. to Portland Intl. Jetport, returning Sun, Apr 13, priced at $200 found 3 days ago
United
Mon, May 5 - Wed, May 7
EWR
Newark Liberty Intl. Airport
PWM
Portland Intl. Jetport
$202 Roundtrip, found 1 day ago
$202
Roundtrip
found 1 day ago
Select United flight, departing Mon, May 5 from Newark Liberty Intl. Airport to Portland Intl. Jetport, returning Wed, May 7, priced at $202 found 1 day ago
JetBlue Airways
Tue, Apr 1 - Tue, Apr 15
RDU
Raleigh - Durham Intl.
PWM
Portland Intl. Jetport
$203 Roundtrip, found 3 days ago
$203
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Tue, Apr 1 from Raleigh - Durham Intl. to Portland Intl. Jetport, returning Tue, Apr 15, priced at $203 found 3 days ago
JetBlue Airways
Sun, Apr 6 - Tue, Apr 15
RDU
Raleigh - Durham Intl.
PWM
Portland Intl. Jetport
$212 Roundtrip, found 3 days ago
$212
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Sun, Apr 6 from Raleigh - Durham Intl. to Portland Intl. Jetport, returning Tue, Apr 15, priced at $212 found 3 days ago
Delta
Thu, Apr 3 - Sun, Apr 13
RDU
Raleigh - Durham Intl.
PWM
Portland Intl. Jetport
$214 Roundtrip, found 21 hours ago
$214
Roundtrip
found 21 hours ago
Select Delta flight, departing Thu, Apr 3 from Raleigh - Durham Intl. to Portland Intl. Jetport, returning Sun, Apr 13, priced at $214 found 21 hours ago
American Airlines
Thu, Apr 3 - Sun, Apr 13
RDU
Raleigh - Durham Intl.
PWM
Portland Intl. Jetport
$217 Roundtrip, found 21 hours ago
$217
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Thu, Apr 3 from Raleigh - Durham Intl. to Portland Intl. Jetport, returning Sun, Apr 13, priced at $217 found 21 hours ago
Breeze Airways
Fri, Aug 22 - Wed, Aug 27
RSW
Southwest Florida Intl.
PWM
Portland Intl. Jetport
$229 Roundtrip, found 2 days ago
$229
Roundtrip
found 2 days ago
Select Breeze Airways flight, departing Fri, Aug 22 from Southwest Florida Intl. to Portland Intl. Jetport, returning Wed, Aug 27, priced at $229 found 2 days ago
Delta
Sat, Apr 19 - Sat, Apr 26
RSW
Southwest Florida Intl.
PWM
Portland Intl. Jetport
$237 Roundtrip, found 20 hours ago
$237
Roundtrip
found 20 hours ago
Select Delta flight, departing Sat, Apr 19 from Southwest Florida Intl. to Portland Intl. Jetport, returning Sat, Apr 26, priced at $237 found 20 hours ago
Delta
Tue, Mar 25 - Mon, Mar 31
OMA
Eppley Field
PWM
Portland Intl. Jetport
$325 Roundtrip, found 18 hours ago
$325
Roundtrip
found 18 hours ago
Select Delta flight, departing Tue, Mar 25 from Eppley Field to Portland Intl. Jetport, returning Mon, Mar 31, priced at $325 found 18 hours ago
Delta
Sat, Jul 19 - Tue, Jul 22
AEX
Alexandria Intl.
PWM
Portland Intl. Jetport
$536 Roundtrip, found 1 day ago
$536
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Jul 19 from Alexandria Intl. to Portland Intl. Jetport, returning Tue, Jul 22, priced at $536 found 1 day ago

Cheap Flights to Sanford

Fall in love at first flight with your vacation to Sanford by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Sanford on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Sanford, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Sanford

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Sanford with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the PWM airport.

What is the cheapest month to fly to Sanford?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Sanford are in April, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Sanford?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Sanford.

What airport is best to fly into Sanford?

When you’re planning your trip to Sanford, convenience is the name of the game. Luckily, Sanford Sanford Seacoast Regional Airport is nearby so you can deplane and get going on checking off everything on your Sanford must-do list.

How much are flights to Sanford?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Sanford on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $160, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Sanford?

The trick to saving a stack of cash on your flight to Sanford? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $160 right now, why wait?

Sanford Flight Information
Destination airport
Portland Intl. Jetport
Destination airport IATA code
PWM
Roundtrip price
$310

Last Minute Hotel Deals in Sanford

Huttopia Southern Maine
Huttopia Southern Maine
2.5 out of 5
149 Sand Pond Rd, Sanford, ME
Book a stay at this family-friendly cabin in Sanford. Enjoy free parking, laundry facilities, and a picnic area. Popular attractions Pine Hollow Little Par Three ...
8.6/10 Excellent! (29 reviews)
"I have stayed here several times. It’s a great way to camp without all the fuss. You feel like you’re enjoying nature without having to pack a bunch of essentials. We stayed in a king bedroom with shower and bathroom. Everything you need is there and it’s close to grocery stores. The pond is wonderful. ..."

Reviewed on Sep 9, 2024

Get rates
Huttopia Southern Maine
Cliff House Maine
Cliff House Maine
4.5 out of 5
591 Shore Road, Cape Neddick, ME
The price is $564 per night from Mar 13 to Mar 14
$564
includes taxes & fees
Mar 13 - Mar 14
Stay at this 4.5-star luxury resort in Cape Neddick. Enjoy free parking, an outdoor pool, and a full-service spa. Our guests praise the helpful staff and the ...
9.4/10 Exceptional! (1,000 reviews)
"Beautiful resort! Everything was perfect"

Reviewed on Feb 22, 2025

Cliff House Maine
Hampton Inn Portsmouth Central
Hampton Inn Portsmouth Central
2.5 out of 5
99 Durgin Ln, Portsmouth, NH
The price is $101 per night from Mar 30 to Mar 31
$101
includes taxes & fees
Mar 30 - Mar 31
Book a stay at this business-friendly hotel in Portsmouth. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,007 reviews)
"The staff were wonderful. The room was clean and we had everything we needed. The hotel is pet friendly. However, we stayed here 1 week ago and then last night. A week ago I noticed lots of dog poop that some pet owner(s) did not pick up. A week later, it was still there in the same spot. The bushes ..."

Reviewed on Mar 3, 2025

Hampton Inn Portsmouth Central
Anchorage Inn and Resort
Anchorage Inn and Resort
3 out of 5
265 Long Beach Avenue, York Beach, ME
The price is $130 per night from Mar 7 to Mar 8
$130
includes taxes & fees
Mar 7 - Mar 8
Stay at this 3-star beach hotel in York Beach. Enjoy free WiFi, free parking, and 2 indoor pools. Our guests praise the pool and the helpful staff in our reviews. ...
8.8/10 Excellent! (1,003 reviews)
"Best birthday weekend ever. It’s right on the beach and you’ll see beautiful sunrises/sunsets"

Reviewed on Mar 3, 2025

Anchorage Inn and Resort
Hampton Inn & Suites Portsmouth Downtown
Hampton Inn & Suites Portsmouth Downtown
3 out of 5
23 Portwalk Pl, Portsmouth, NH
The price is $147 per night from Mar 16 to Mar 17
$147
includes taxes & fees
Mar 16 - Mar 17
Stay at this 3-star business-friendly hotel in Portsmouth. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,002 reviews)
"This was our second stay at rhis hotel. The breakfast is great. The.staff were friendly and competent! Great location right downtown."

Reviewed on Mar 4, 2025

Hampton Inn & Suites Portsmouth Downtown
Holiday Inn Portsmouth, an IHG Hotel
Holiday Inn Portsmouth, an IHG Hotel
3 out of 5
300 Woodbury Ave, Portsmouth, NH
The price is $111 per night from Mar 30 to Mar 31
$111
includes taxes & fees
Mar 30 - Mar 31
Stay at this 3-star hotel in Portsmouth. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
7.8/10 Good! (965 reviews)
"The bed was super comfortable. The room and hotel were extremely clean even while a snow storm hit they were actively cleaning the parking lot and lobby floors. My only negative was that the room was not ready at our 3pm arrival. We waited about 30 minutes for a room to be ready."

Reviewed on Feb 21, 2025

Holiday Inn Portsmouth, an IHG Hotel
Anchorage by the Sea
Anchorage by the Sea
3 out of 5
125 Shore Road, Ogunquit, ME
The price is $217 per night from Apr 6 to Apr 7
$217
includes taxes & fees
Apr 6 - Apr 7
Stay at this 3-star hotel in Ogunquit. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the property condition in ...
9/10 Wonderful! (658 reviews)
"We love staying at this property, the restaurant at the hotel was delicious and the room was good size, looking forward to another visit soon"

Reviewed on Feb 2, 2025

Anchorage by the Sea
The Colony Hotel
The Colony Hotel
3 out of 5
140 Ocean Ave, Kennebunkport, ME
The price is $217 per night from Mar 9 to Mar 10
$217
includes taxes & fees
Mar 9 - Mar 10
Book a stay at this business-friendly hotel in Kennebunkport. Enjoy free WiFi, free parking, and private pools. Our guests praise the helpful staff and the property ...
8.8/10 Excellent! (771 reviews)
"Absolutely beautiful area. Staff is so nice. Many options at the on site Marketplace. Wonderful smoothie."

Reviewed on Mar 1, 2025

The Colony Hotel
See all 3,584 properties in Sanford
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.