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Southwest Illinois

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Southwest Illinois Flights as Low as $140

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Spirit Airlines
Mon, Aug 25 - Thu, Sep 4
EWR
Newark Liberty Intl. Airport
STL
Lambert-St. Louis Intl.
$140 Roundtrip, found 13 hours ago
$140
Roundtrip
found 13 hours ago
Select Spirit Airlines flight, departing Mon, Aug 25 from Newark Liberty Intl. Airport to Lambert-St. Louis Intl., returning Thu, Sep 4, priced at $140 found 13 hours ago
Spirit Airlines
Sun, Aug 17 - Mon, Aug 18
PHL
Philadelphia Intl.
STL
Lambert-St. Louis Intl.
$169 Roundtrip, found 3 days ago
$169
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Sun, Aug 17 from Philadelphia Intl. to Lambert-St. Louis Intl., returning Mon, Aug 18, priced at $169 found 3 days ago
Delta
Sat, Sep 27 - Sat, Sep 27
SEA
Seattle - Tacoma Intl.
STL
Lambert-St. Louis Intl.
$174 Roundtrip, found 9 hours ago
$174
Roundtrip
found 9 hours ago
Select Delta flight, departing Sat, Sep 27 from Seattle - Tacoma Intl. to Lambert-St. Louis Intl., returning Sat, Sep 27, priced at $174 found 9 hours ago
United
Wed, Aug 27 - Thu, Sep 4
EWR
Newark Liberty Intl. Airport
STL
Lambert-St. Louis Intl.
$176 Roundtrip, found 7 hours ago
$176
Roundtrip
found 7 hours ago
Select United flight, departing Wed, Aug 27 from Newark Liberty Intl. Airport to Lambert-St. Louis Intl., returning Thu, Sep 4, priced at $176 found 7 hours ago
Delta
Tue, Aug 26 - Tue, Sep 2
SEA
Seattle - Tacoma Intl.
STL
Lambert-St. Louis Intl.
$179 Roundtrip, found 3 days ago
$179
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Aug 26 from Seattle - Tacoma Intl. to Lambert-St. Louis Intl., returning Tue, Sep 2, priced at $179 found 3 days ago
American Airlines
Wed, Aug 27 - Wed, Sep 3
SEA
Seattle - Tacoma Intl.
STL
Lambert-St. Louis Intl.
$179 Roundtrip, found 4 days ago
$179
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Aug 27 from Seattle - Tacoma Intl. to Lambert-St. Louis Intl., returning Wed, Sep 3, priced at $179 found 4 days ago
United
Thu, Sep 25 - Tue, Sep 30
SEA
Seattle - Tacoma Intl.
STL
Lambert-St. Louis Intl.
$181 Roundtrip, found 9 hours ago
$181
Roundtrip
found 9 hours ago
Select United flight, departing Thu, Sep 25 from Seattle - Tacoma Intl. to Lambert-St. Louis Intl., returning Tue, Sep 30, priced at $181 found 9 hours ago
Spirit Airlines
Fri, Aug 22 - Thu, Aug 28
EWR
Newark Liberty Intl. Airport
STL
Lambert-St. Louis Intl.
$182 Roundtrip, found 5 days ago
$182
Roundtrip
found 5 days ago
Select Spirit Airlines flight, departing Fri, Aug 22 from Newark Liberty Intl. Airport to Lambert-St. Louis Intl., returning Thu, Aug 28, priced at $182 found 5 days ago
Spirit Airlines
Thu, Aug 7 - Thu, Aug 14
PHL
Philadelphia Intl.
STL
Lambert-St. Louis Intl.
$185 Roundtrip, found 3 days ago
$185
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Thu, Aug 7 from Philadelphia Intl. to Lambert-St. Louis Intl., returning Thu, Aug 14, priced at $185 found 3 days ago
Spirit Airlines
Mon, Aug 25 - Thu, Aug 28
EWR
Newark Liberty Intl. Airport
STL
Lambert-St. Louis Intl.
$187 Roundtrip, found 3 days ago
$187
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Mon, Aug 25 from Newark Liberty Intl. Airport to Lambert-St. Louis Intl., returning Thu, Aug 28, priced at $187 found 3 days ago
United
Wed, Aug 27 - Wed, Sep 3
SEA
Seattle - Tacoma Intl.
STL
Lambert-St. Louis Intl.
$188 Roundtrip, found 4 days ago
$188
Roundtrip
found 4 days ago
Select United flight, departing Wed, Aug 27 from Seattle - Tacoma Intl. to Lambert-St. Louis Intl., returning Wed, Sep 3, priced at $188 found 4 days ago
Frontier Airlines
Sat, Aug 23 - Mon, Aug 25
EWR
Newark Liberty Intl. Airport
STL
Lambert-St. Louis Intl.
$222 Roundtrip, found 5 days ago
$222
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Sat, Aug 23 from Newark Liberty Intl. Airport to Lambert-St. Louis Intl., returning Mon, Aug 25, priced at $222 found 5 days ago
Hawaiian Airlines
Mon, Sep 29 - Tue, Sep 30
SEA
Seattle - Tacoma Intl.
STL
Lambert-St. Louis Intl.
$227 Roundtrip, found 9 hours ago
$227
Roundtrip
found 9 hours ago
Select Hawaiian Airlines flight, departing Mon, Sep 29 from Seattle - Tacoma Intl. to Lambert-St. Louis Intl., returning Tue, Sep 30, priced at $227 found 9 hours ago
Frontier Airlines
Thu, Oct 16 - Fri, Oct 17
TTN
Mercer
STL
Lambert-St. Louis Intl.
$228 Roundtrip, found 1 day ago
$228
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Oct 16 from Mercer to Lambert-St. Louis Intl., returning Fri, Oct 17, priced at $228 found 1 day ago
Alaska Airlines
Fri, Sep 26 - Tue, Sep 30
SEA
Seattle - Tacoma Intl.
STL
Lambert-St. Louis Intl.
$231 Roundtrip, found 9 hours ago
$231
Roundtrip
found 9 hours ago
Select Alaska Airlines flight, departing Fri, Sep 26 from Seattle - Tacoma Intl. to Lambert-St. Louis Intl., returning Tue, Sep 30, priced at $231 found 9 hours ago
Bargain Flight
Sun, Aug 31 - Sat, Sep 6
PAE
Seattle Paine Field Intl. Airport
STL
Lambert-St. Louis Intl.
$536 Roundtrip, found 3 days ago
$536
Roundtrip
found 3 days ago
Select Bargain Flight flight, departing Sun, Aug 31 from Seattle Paine Field Intl. Airport to Lambert-St. Louis Intl., returning Sat, Sep 6, priced at $536 found 3 days ago

Cheap Flights to Southwest Illinois

Fall in love at first flight with your vacation to Southwest Illinois by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Southwest Illinois on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Southwest Illinois, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Southwest Illinois

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Southwest Illinois with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the STL airport.

What is the cheapest month to fly to Southwest Illinois?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Southwest Illinois are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Southwest Illinois?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to Southwest Illinois.

What airport is best to fly into Southwest Illinois?

When you’re planning your trip to Southwest Illinois, convenience is the name of the game. Luckily, Southwest Illinois Williamson County Regional Airport is nearby so you can deplane and get going on checking off everything on your Southwest Illinois must-do list.

How much are flights to Southwest Illinois?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Southwest Illinois on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $140, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Southwest Illinois?

The trick to saving a stack of cash on your flight to Southwest Illinois? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $140 right now, why wait?

Southwest Illinois Flight Information
Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Roundtrip price
$120

Last Minute Hotel Deals in Southwest Illinois

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

3 out of 5
145 North 44th Street , Mount Vernon, IL
Stay at this 3-star business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,404 reviews)
Great value
"Great experience, but they need better pillows."

Reviewed on Jul 27, 2025

Get rates
Drury Plaza Hotel Mt. Vernon
Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach

2.5 out of 5
1240 E Chain Of Rocks Rd, Granite City, IL
Stay at this hotel in Granite City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.8/10 Good! (460 reviews)
"You get what you pay for"

Reviewed on Jul 27, 2025

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Red Lion Inn & Suites Pontoon Beach
Best Western Plus Pontoon Beach

Best Western Plus Pontoon Beach

3 out of 5
4 Regency Pkwy, Granite City, IL
Stay at this 3-star business-friendly hotel in Granite City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (713 reviews)
"It was roomy and clean."

Reviewed on Jul 27, 2025

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Best Western Plus Pontoon Beach
Super 8 by Wyndham O'Fallon

Super 8 by Wyndham O'Fallon

2 out of 5
1100 Eastgate Dr, O'Fallon, IL
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.4/10 Good! (1,030 reviews)
"Friendly staff and helpful"

Reviewed on Jul 26, 2025

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Super 8 by Wyndham O'Fallon
Drury Inn & Suites Marion

Drury Inn & Suites Marion

3 out of 5
2706 W DeYoung St, Marion, IL
Stay at this 3-star business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,016 reviews)
"This hotel was excellent! Clean and friendly staff"

Reviewed on Jul 26, 2025

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Drury Inn & Suites Marion
Quality Inn & Suites near St. Louis and I-255

Quality Inn & Suites near St. Louis and I-255

2.5 out of 5
1607 Pontiac Dr, East St. Louis, IL
Book a stay at this business-friendly hotel in East St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
7.4/10 Good! (1,009 reviews)
Good stay
"Friendly staff, clean room, hotel not in the best area."

Reviewed on Jul 19, 2025

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Quality Inn & Suites near St. Louis and I-255
Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

3 out of 5
12 Ludwig Dr, Fairview Heights, IL
Book a stay at this business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,015 reviews)
"The staff were very friendly and the breakfast was be better than average!"

Reviewed on Jul 24, 2025

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Drury Inn & Suites St. Louis Fairview Heights
Days Inn & Suites by Wyndham Caseyville

Days Inn & Suites by Wyndham Caseyville

2.5 out of 5
2423 Old Country Inn Drive, Caseyville, IL
Book a stay at this business-friendly hotel in Caseyville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Pleasant Ridge Park and Cahokia ...
3.8/10 (265 reviews)
"Refuse to give me more than one extra towel"

Reviewed on Jul 23, 2025

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Days Inn & Suites by Wyndham Caseyville
See all 684 properties in Southwest Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.