Search Cheap Flights to
Southwest Illinois

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Southwest Illinois Flights as Low as $90

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Thu, Aug 21 - Thu, Aug 28
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$90 Roundtrip, found 3 hours ago
$90
Roundtrip
found 3 hours ago
Select Frontier Airlines flight, departing Thu, Aug 21 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Thu, Aug 28, priced at $90 found 3 hours ago
Frontier Airlines
Thu, Jul 24 - Sun, Jul 27
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$93 Roundtrip, found 6 days ago
$93
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Thu, Jul 24 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Sun, Jul 27, priced at $93 found 6 days ago
Frontier Airlines
Thu, Aug 21 - Sun, Aug 31
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$115 Roundtrip, found 1 day ago
$115
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Aug 21 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Sun, Aug 31, priced at $115 found 1 day ago
Frontier Airlines
Thu, Aug 21 - Thu, Aug 28
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$120 Roundtrip, found 3 hours ago
$120
Roundtrip
found 3 hours ago
Select Frontier Airlines flight, departing Thu, Aug 21 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Thu, Aug 28, priced at $120 found 3 hours ago
Frontier Airlines
Thu, Jul 24 - Sun, Aug 3
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$122 Roundtrip, found 6 days ago
$122
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Thu, Jul 24 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Sun, Aug 3, priced at $122 found 6 days ago
Frontier Airlines
Sat, Oct 4 - Sat, Oct 11
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$129 Roundtrip, found 2 hours ago
$129
Roundtrip
found 2 hours ago
Select Frontier Airlines flight, departing Sat, Oct 4 from Denver Intl. to Lambert-St. Louis Intl., returning Sat, Oct 11, priced at $129 found 2 hours ago
American Airlines
Tue, Aug 26 - Tue, Aug 26
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$136 Roundtrip, found 2 hours ago
$136
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Tue, Aug 26 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Tue, Aug 26, priced at $136 found 2 hours ago
United
Sat, Oct 4 - Sat, Oct 11
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$157 Roundtrip, found 2 hours ago
$157
Roundtrip
found 2 hours ago
Select United flight, departing Sat, Oct 4 from Denver Intl. to Lambert-St. Louis Intl., returning Sat, Oct 11, priced at $157 found 2 hours ago
Spirit Airlines
Thu, Aug 7 - Thu, Aug 14
PHX
Sky Harbor Intl.
STL
Lambert-St. Louis Intl.
$167 Roundtrip, found 1 day ago
$167
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Thu, Aug 7 from Sky Harbor Intl. to Lambert-St. Louis Intl., returning Thu, Aug 14, priced at $167 found 1 day ago
Delta
Tue, Aug 26 - Tue, Aug 26
DAL
Love Field
STL
Lambert-St. Louis Intl.
$194 Roundtrip, just found
$194
Roundtrip
just found
Select Delta flight, departing Tue, Aug 26 from Love Field to Lambert-St. Louis Intl., returning Tue, Aug 26, priced at $194 just found
Delta
Tue, Aug 26 - Tue, Aug 26
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$194 Roundtrip, found 2 hours ago
$194
Roundtrip
found 2 hours ago
Select Delta flight, departing Tue, Aug 26 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Tue, Aug 26, priced at $194 found 2 hours ago
American Airlines
Fri, Aug 22 - Mon, Aug 25
DEN
Denver Intl.
PAH
Barkley Regional
$363 Roundtrip, found 3 hours ago
$363
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Fri, Aug 22 from Denver Intl. to Barkley Regional, returning Mon, Aug 25, priced at $363 found 3 hours ago
American Airlines
Wed, Aug 20 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$375 Roundtrip, just found
$375
Roundtrip
just found
Select American Airlines flight, departing Wed, Aug 20 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $375 just found
American Airlines
Wed, Sep 24 - Tue, Sep 30
PHX
Sky Harbor Intl.
PAH
Barkley Regional
$522 Roundtrip, found 16 hours ago
$522
Roundtrip
found 16 hours ago
Select American Airlines flight, departing Wed, Sep 24 from Sky Harbor Intl. to Barkley Regional, returning Tue, Sep 30, priced at $522 found 16 hours ago
American Airlines
Wed, Jul 9 - Mon, Jul 14
BTR
Baton Rouge Metropolitan
PAH
Barkley Regional
$731 Roundtrip, found 1 day ago
$731
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Jul 9 from Baton Rouge Metropolitan to Barkley Regional, returning Mon, Jul 14, priced at $731 found 1 day ago
Delta
Tue, Jul 8 - Fri, Jul 11
BTR
Baton Rouge Metropolitan
STL
Lambert-St. Louis Intl.
$745 Roundtrip, found 3 days ago
$745
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Jul 8 from Baton Rouge Metropolitan to Lambert-St. Louis Intl., returning Fri, Jul 11, priced at $745 found 3 days ago

Cheap Flights to Southwest Illinois

Fall in love at first flight with your vacation to Southwest Illinois by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Southwest Illinois on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Southwest Illinois, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Southwest Illinois

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Southwest Illinois with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the STL airport.

What is the cheapest month to fly to Southwest Illinois?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Southwest Illinois are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Southwest Illinois?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Southwest Illinois.

What airport is best to fly into Southwest Illinois?

When you’re planning your trip to Southwest Illinois, convenience is the name of the game. Luckily, Southwest Illinois Williamson County Regional Airport is nearby so you can deplane and get going on checking off everything on your Southwest Illinois must-do list.

How much are flights to Southwest Illinois?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Southwest Illinois on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $90, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Southwest Illinois?

The trick to saving a stack of cash on your flight to Southwest Illinois? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $90 right now, why wait?

Southwest Illinois Flight Information
Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Roundtrip price
$60

Last Minute Hotel Deals in Southwest Illinois

Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. Vernon
3 out of 5
145 North 44th Street , Mount Vernon, IL
Stay at this 3-star business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,373 reviews)
"Very happy with our 1 night stay with our littles"

Reviewed on Jul 5, 2025

Get rates
Drury Plaza Hotel Mt. Vernon
Best Western Plus Pontoon Beach
Best Western Plus Pontoon Beach
3 out of 5
4 Regency Pkwy, Granite City, IL
Stay at this 3-star business-friendly hotel in Granite City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (684 reviews)
"Pool was great n breakfast good. Only thing that was bad was that our fitted sheet had several tears n holes in it. Room was clean."

Reviewed on Jul 3, 2025

Get rates
Best Western Plus Pontoon Beach
Quality Inn & Suites near St. Louis and I-255
Quality Inn & Suites near St. Louis and I-255
2.5 out of 5
1607 Pontiac Dr, East St. Louis, IL
Book a stay at this business-friendly hotel in East St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
7.4/10 Good! (999 reviews)
"Gvg"

Reviewed on Jun 30, 2025

Get rates
Quality Inn & Suites near St. Louis and I-255
Super 8 by Wyndham O'Fallon
Super 8 by Wyndham O'Fallon
2 out of 5
1100 Eastgate Dr, O'Fallon, IL
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.4/10 Good! (1,004 reviews)
"A little out of the way, but good value"

Reviewed on Jul 3, 2025

Get rates
Super 8 by Wyndham O'Fallon
Red Lion Inn & Suites Pontoon Beach
Red Lion Inn & Suites Pontoon Beach
2.5 out of 5
1240 E Chain Of Rocks Rd, Granite City, IL
Stay at this hotel in Granite City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.8/10 Good! (418 reviews)
"Thank you, lovely staff and nice stay. I will be back! Sincerely, Amber Mann"

Reviewed on Jul 5, 2025

Get rates
Red Lion Inn & Suites Pontoon Beach
Drury Inn & Suites St. Louis Fairview Heights
Drury Inn & Suites St. Louis Fairview Heights
3 out of 5
12 Ludwig Dr, Fairview Heights, IL
Book a stay at this business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,005 reviews)
"Friendliest staff ever! Free cocktails and dinner..wow!"

Reviewed on Jul 4, 2025

Get rates
Drury Inn & Suites St. Louis Fairview Heights
Days Inn & Suites by Wyndham Caseyville
Days Inn & Suites by Wyndham Caseyville
2.5 out of 5
2423 Old Country Inn Drive, Caseyville, IL
Book a stay at this business-friendly hotel in Caseyville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Pleasant Ridge Park and Cahokia ...
3.8/10 (243 reviews)
"Maybe they need to repair the ice machine and bring back the snacks machines with card options. Maybe a convenient store inside. Repair the coin washer plus other things. But I still think it’s the best option to do the main things you do on a room: rest and be relaxed."

Reviewed on Jun 30, 2025

Get rates
Days Inn & Suites by Wyndham Caseyville
DoubleTree by Hilton Mt. Vernon
DoubleTree by Hilton Mt. Vernon
4 out of 5
222 Potomac Blvd, Mount Vernon, IL
Book a stay at this business-friendly hotel in Mount Vernon. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the ...
8.2/10 Very Good! (705 reviews)
"Service was excellent"

Reviewed on Jun 21, 2025

Get rates
DoubleTree by Hilton Mt. Vernon
See all 675 properties in Southwest Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.