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Southwest Illinois

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Southwest Illinois Flights as Low as $230

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Tue, Aug 11 - Tue, Aug 18
TPA
Tampa Intl.
STL
Lambert-St. Louis Intl.
$230 Roundtrip, found 17 hours ago
$230
Roundtrip
found 17 hours ago
Select Frontier Airlines flight, departing Tue, Aug 11 from Tampa Intl. to Lambert-St. Louis Intl., returning Tue, Aug 18, priced at $230 found 17 hours ago
Delta
Tue, Aug 11 - Tue, Aug 18
TPA
Tampa Intl.
STL
Lambert-St. Louis Intl.
$235 Roundtrip, found 17 hours ago
$235
Roundtrip
found 17 hours ago
Select Delta flight, departing Tue, Aug 11 from Tampa Intl. to Lambert-St. Louis Intl., returning Tue, Aug 18, priced at $235 found 17 hours ago
Delta
Tue, Aug 11 - Tue, Aug 18
TPA
Tampa Intl.
STL
Lambert-St. Louis Intl.
$239 Roundtrip, found 17 hours ago
$239
Roundtrip
found 17 hours ago
Select Delta flight, departing Tue, Aug 11 from Tampa Intl. to Lambert-St. Louis Intl., returning Tue, Aug 18, priced at $239 found 17 hours ago
American Airlines
Tue, Aug 11 - Tue, Aug 18
TPA
Tampa Intl.
STL
Lambert-St. Louis Intl.
$239 Roundtrip, found 17 hours ago
$239
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Tue, Aug 11 from Tampa Intl. to Lambert-St. Louis Intl., returning Tue, Aug 18, priced at $239 found 17 hours ago
Frontier Airlines
Tue, Aug 11 - Tue, Aug 18
TPA
Tampa Intl.
STL
Lambert-St. Louis Intl.
$240 Roundtrip, found 17 hours ago
$240
Roundtrip
found 17 hours ago
Select Frontier Airlines flight, departing Tue, Aug 11 from Tampa Intl. to Lambert-St. Louis Intl., returning Tue, Aug 18, priced at $240 found 17 hours ago
Bargain Flight
Tue, Jul 7 - Wed, Jul 15
BWI
Baltimore Washington Intl. Thurgood Marshall
STL
Lambert-St. Louis Intl.
$243 Roundtrip, found 14 hours ago
$243
Roundtrip
found 14 hours ago
Select Bargain Flight flight, departing Tue, Jul 7 from Baltimore Washington Intl. Thurgood Marshall to Lambert-St. Louis Intl., returning Wed, Jul 15, priced at $243 found 14 hours ago
Frontier Airlines
Tue, Jul 7 - Wed, Jul 15
BWI
Baltimore Washington Intl. Thurgood Marshall
STL
Lambert-St. Louis Intl.
$264 Roundtrip, found 14 hours ago
$264
Roundtrip
found 14 hours ago
Select Frontier Airlines flight, departing Tue, Jul 7 from Baltimore Washington Intl. Thurgood Marshall to Lambert-St. Louis Intl., returning Wed, Jul 15, priced at $264 found 14 hours ago
United
Tue, Aug 11 - Tue, Aug 18
TPA
Tampa Intl.
STL
Lambert-St. Louis Intl.
$273 Roundtrip, found 17 hours ago
$273
Roundtrip
found 17 hours ago
Select United flight, departing Tue, Aug 11 from Tampa Intl. to Lambert-St. Louis Intl., returning Tue, Aug 18, priced at $273 found 17 hours ago
Frontier Airlines
Tue, Aug 11 - Tue, Aug 18
TPA
Tampa Intl.
STL
Lambert-St. Louis Intl.
$274 Roundtrip, found 17 hours ago
$274
Roundtrip
found 17 hours ago
Select Frontier Airlines flight, departing Tue, Aug 11 from Tampa Intl. to Lambert-St. Louis Intl., returning Tue, Aug 18, priced at $274 found 17 hours ago
American Airlines
Tue, Aug 11 - Tue, Aug 18
TPA
Tampa Intl.
STL
Lambert-St. Louis Intl.
$279 Roundtrip, found 17 hours ago
$279
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Tue, Aug 11 from Tampa Intl. to Lambert-St. Louis Intl., returning Tue, Aug 18, priced at $279 found 17 hours ago
Delta
Tue, Aug 11 - Tue, Aug 18
TPA
Tampa Intl.
STL
Lambert-St. Louis Intl.
$280 Roundtrip, found 17 hours ago
$280
Roundtrip
found 17 hours ago
Select Delta flight, departing Tue, Aug 11 from Tampa Intl. to Lambert-St. Louis Intl., returning Tue, Aug 18, priced at $280 found 17 hours ago
Frontier Airlines
Tue, Aug 11 - Tue, Aug 18
TPA
Tampa Intl.
STL
Lambert-St. Louis Intl.
$280 Roundtrip, found 17 hours ago
$280
Roundtrip
found 17 hours ago
Select Frontier Airlines flight, departing Tue, Aug 11 from Tampa Intl. to Lambert-St. Louis Intl., returning Tue, Aug 18, priced at $280 found 17 hours ago
American Airlines
Tue, Aug 11 - Tue, Aug 18
TPA
Tampa Intl.
STL
Lambert-St. Louis Intl.
$285 Roundtrip, found 17 hours ago
$285
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Tue, Aug 11 from Tampa Intl. to Lambert-St. Louis Intl., returning Tue, Aug 18, priced at $285 found 17 hours ago
United
Tue, Jul 7 - Tue, Jul 14
BWI
Baltimore Washington Intl. Thurgood Marshall
CGI
Cape Girardeau Municipal
$440 Roundtrip, found 21 hours ago
$440
Roundtrip
found 21 hours ago
Select United flight, departing Tue, Jul 7 from Baltimore Washington Intl. Thurgood Marshall to Cape Girardeau Municipal, returning Tue, Jul 14, priced at $440 found 21 hours ago
Bargain Flight
Thu, Jun 11 - Tue, Jun 23
BWI
Baltimore Washington Intl. Thurgood Marshall
PAH
Barkley Regional
$459 Roundtrip, found 1 day ago
$459
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Thu, Jun 11 from Baltimore Washington Intl. Thurgood Marshall to Barkley Regional, returning Tue, Jun 23, priced at $459 found 1 day ago
American Airlines
Sat, Jul 11 - Sat, Jul 18
TPA
Tampa Intl.
CGI
Cape Girardeau Municipal
$553 Roundtrip, found 21 hours ago
$553
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Sat, Jul 11 from Tampa Intl. to Cape Girardeau Municipal, returning Sat, Jul 18, priced at $553 found 21 hours ago

Cheap Flights to Southwest Illinois

Fall in love at first flight with your vacation to Southwest Illinois by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Southwest Illinois on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Southwest Illinois, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Southwest Illinois

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Southwest Illinois with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the STL airport.

What is the cheapest month to fly to Southwest Illinois?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Southwest Illinois are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Southwest Illinois?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 14 to choose from for your flight to Southwest Illinois.

What airport is best to fly into Southwest Illinois?

When you’re planning your trip to Southwest Illinois, convenience is the name of the game. Luckily, Southwest Illinois Veterans Airport of Southern Illinois Airport is nearby so you can deplane and get going on checking off everything on your Southwest Illinois must-do list.

How much are flights to Southwest Illinois?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Southwest Illinois on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $230, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Southwest Illinois?

The trick to saving a stack of cash on your flight to Southwest Illinois? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $230 right now, why wait?

Southwest Illinois Flight Information
Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Roundtrip price
$99

Last Minute Hotel Deals in Southwest Illinois

Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

3 out of 5
12 Ludwig Dr Fairview Heights IL
Book a stay at this business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,010 reviews)
"All of the staff were extremely friendly. The full hot breakfast and evening food/beverages were a great plus!"

Reviewed on May 26, 2026

Get rates
Drury Inn & Suites St. Louis Fairview Heights
Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

3.5 out of 5
145 North 44th Street  Mount Vernon IL
Book a stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,693 reviews)
"Excellent breakfast and selection in the evening. Also, one of the better fitness rooms in this price range of a hotel. Very clean, staff was impeccably polite, and an overall wonderful experience."

Reviewed on May 27, 2026

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Drury Plaza Hotel Mt. Vernon
Walker's Bluff Casino Resort

Walker's Bluff Casino Resort

4.5 out of 5
777 Walkers Bluff Way Carterville IL
Book a stay at this luxury resort in Carterville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms ...
9.4/10 Exceptional! (456 reviews)
"Very nice place & will stay there again. Dan K"

Reviewed on May 24, 2026

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Walker's Bluff Casino Resort
Super 8 by Wyndham O'Fallon

Super 8 by Wyndham O'Fallon

2 out of 5
1100 Eastgate Dr O'Fallon IL
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (1,001 reviews)
"bugs in bed are automatic negative reviews. no light at the bathroom. stains all over and not even one plastic cup. hallway is disgusting"

Reviewed on May 24, 2026

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Super 8 by Wyndham O'Fallon
Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

3 out of 5
1118 Central Park Drive O'Fallon IL
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,000 reviews)
"old and unkept"

Reviewed on May 26, 2026

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Drury Inn & Suites St. Louis O'Fallon, IL
Quality Inn O'Fallon IL - St. Louis

Quality Inn O'Fallon IL - St. Louis

3 out of 5
1409 W US 50 O'Fallon IL
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.4/10 Good! (1,005 reviews)
"It would’ve been nice if the pool water was a little bit warmer"

Reviewed on May 26, 2026

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Quality Inn O'Fallon IL - St. Louis
Holiday Inn Express & Suites Mount Vernon by IHG

Holiday Inn Express & Suites Mount Vernon by IHG

2.5 out of 5
300 Potomac Blvd Mount Vernon IL
Book a stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,000 reviews)
"Staff was efficient, personable, and helpful; breakfast was great!"

Reviewed on May 24, 2026

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Holiday Inn Express & Suites Mount Vernon by IHG
Drury Inn & Suites Marion

Drury Inn & Suites Marion

3 out of 5
2706 W DeYoung St Marion IL
Book a stay at this business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,008 reviews)
"Great accommodations, with free drinks and food. Very clean"

Reviewed on May 26, 2026

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Drury Inn & Suites Marion
See all 764 properties in Southwest Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.