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Hotels in Southwest Illinois

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Last Minute Hot Rate® Hotel Deals in Southwest Illinois

We Hide Hotel Names So You Can Find 4-Star Hotels At 2-Star Prices. Choose the Location, Star Rating & Amenities. Let Hotwire Find You the Best Deal. Book Today!

Choose from 687 Southwest Illinois Hotel Deals

Super 8 by Wyndham O'Fallon
Super 8 by Wyndham O'Fallon
2 out of 5
1100 Eastgate Dr, O'Fallon, IL
  • 3 hours drive from Southern Illinois University
The price is $54 per night from Jun 23 to Jun 24
$54
per night
Jun 23 - Jun 24
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
7.6/10 Good! (1,004 reviews)
"Room could use some paint, but it was clean, quiet and the staff was efficient and polite."

Reviewed on Jun 11, 2024

Super 8 by Wyndham O'Fallon
Drury Inn & Suites Mt. Vernon
Drury Inn & Suites Mt. Vernon
3 out of 5
145 North 44th Street , Mount Vernon, IL
  • 2 hours drive from Southern Illinois University
The price is $112 per night from Jun 23 to Jun 24
$112
per night
Jun 23 - Jun 24
Book a stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,139 reviews)
"Everything was great. Thanks for your kindness!"

Reviewed on Jun 13, 2024

Drury Inn & Suites Mt. Vernon
Drury Inn & Suites St. Louis O'Fallon, IL
Drury Inn & Suites St. Louis O'Fallon, IL
3 out of 5
1118 Central Park Drive, O'Fallon, IL
  • 3 hours drive from Southern Illinois University
The price is $135 per night from Jul 7 to Jul 8
$135
per night
Jul 7 - Jul 8
Stay at this 3-star business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,001 reviews)
"Everything was Excellent"

Reviewed on Jun 9, 2024

Drury Inn & Suites St. Louis O'Fallon, IL
Drury Inn & Suites St. Louis Fairview Heights
Drury Inn & Suites St. Louis Fairview Heights
3 out of 5
12 Ludwig Dr, Fairview Heights, IL
  • 3 hours drive from Southern Illinois University
The price is $127 per night from Jul 8 to Jul 9
$127
per night
Jul 8 - Jul 9
Book a stay at this business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
9/10 Wonderful! (1,006 reviews)
"Everything we expect from a Drury."

Reviewed on Jun 14, 2024

Drury Inn & Suites St. Louis Fairview Heights
Drury Inn & Suites Marion
Drury Inn & Suites Marion
3 out of 5
2706 W DeYoung St, Marion, IL
  • 42 min drive from Southern Illinois University
The price is $117 per night from Jul 7 to Jul 8
$117
per night
Jul 7 - Jul 8
Stay at this 3-star business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,000 reviews)
"Had a great stay and the kickback was a nice end to a day full of driving!"

Reviewed on Jun 9, 2024

Drury Inn & Suites Marion
DoubleTree by Hilton Mt. Vernon
DoubleTree by Hilton Mt. Vernon
4 out of 5
222 Potomac Blvd, Mount Vernon, IL
  • 2 hours drive from Southern Illinois University
The price is $105 per night from Jun 26 to Jun 27
$105
per night
Jun 26 - Jun 27
Stay at this hotel in Mount Vernon. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (523 reviews)
"need better lighting"

Reviewed on Jun 13, 2024

DoubleTree by Hilton Mt. Vernon
Walker's Bluff Casino Resort
Walker's Bluff Casino Resort
4.5 out of 5
777 Walkers Bluff Way, Carterville, IL
  • 19 min drive from Southern Illinois University
The price is $125 per night from Jun 19 to Jun 20
$125
per night
Jun 19 - Jun 20
Stay at this 4.5-star luxury resort in Carterville. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Crab Orchard Golf Club and De Soto ...
9.2/10 Wonderful! (161 reviews)
"Great hotel and casino! Rooms are very nice and the casino is fantastic! Highly recommend!"

Reviewed on Jun 14, 2024

Walker's Bluff Casino Resort
Country Inn & Suites by Radisson, Fairview Heights, IL
Country Inn & Suites by Radisson, Fairview Heights, IL
3 out of 5
140 Ludwig Drive, Fairview Heights, IL
  • 3 hours drive from Southern Illinois University
The price is $98 per night from Jul 1 to Jul 2
$98
per night
Jul 1 - Jul 2
Book a stay at this business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
7.2/10 Good! (596 reviews)
"Great place"

Reviewed on Jun 11, 2024

Country Inn & Suites by Radisson, Fairview Heights, IL
Baymont by Wyndham Marion
Baymont by Wyndham Marion
2.5 out of 5
2608 W Main St, Marion, IL
  • 43 min drive from Southern Illinois University
The price is $77 per night from Jun 17 to Jun 18
$77
per night
Jun 17 - Jun 18
Book a stay at this business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8/10 Very Good! (1,001 reviews)
"Just OK. It served its purpose as a stop on a long trip."

Reviewed on Jun 13, 2024

Baymont by Wyndham Marion
Town & Country Inn
Town & Country Inn
2.5 out of 5
910 Cherry Ln, Troy, IL
  • 3 hours drive from Southern Illinois University
The price is $83 per night from Jun 17 to Jun 18
$83
per night
Jun 17 - Jun 18
Stay at this motel in Troy. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. Popular attractions Bella Vista ...
8.2/10 Very Good! (170 reviews)
"The hotel is convenient to express way, very clean and well maintained. Rooms are spacious and clean. Except the air conditioner was loud in our room. Overall we had a good night sleep, we feel safe."

Reviewed on Jun 10, 2024

Town & Country Inn
Quality Inn & Suites near St. Louis and I-255
Quality Inn & Suites near St. Louis and I-255
2.5 out of 5
1607 Pontiac Dr, East St. Louis, IL
  • 3 hours drive from Southern Illinois University
The price is $76 per night from Jun 20 to Jun 21
$76
per night
Jun 20 - Jun 21
Book a stay at this business-friendly hotel in East St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
7.4/10 Good! (1,002 reviews)
"Clean, quiet and affordable."

Reviewed on Jun 13, 2024

Quality Inn & Suites near St. Louis and I-255
Drury Inn & Suites St. Louis Collinsville
Drury Inn & Suites St. Louis Collinsville
3 out of 5
602 N Bluff Rd, Collinsville, IL
  • 3 hours drive from Southern Illinois University
The price is $108 per night from Jul 7 to Jul 8
$108
per night
Jul 7 - Jul 8
Book a stay at this business-friendly hotel in Collinsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,001 reviews)
"Great location near I55 yet quiet. Nice room and bathroom."

Reviewed on Jun 10, 2024

Drury Inn & Suites St. Louis Collinsville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Southwest Illinois

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Southwest Illinois hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Southwest Illinois.

Choosing the right hotel in Illinois has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Southwest Illinois’s 687 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $54. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Southwest Illinois hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Southwest Illinois. No matter your reason for visiting Southwest Illinois, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Southwest Illinois hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Southwest Illinois for as low as $54.

How many hotels are there in Southwest Illinois?

With over 687 hotels in Southwest Illinois, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $54.

How to find cheap car rentals in Southwest Illinois?

Finding a cheap car rental deal in Southwest Illinois is as easy as scoring cheap hotels in Southwest Illinois. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Southwest Illinois now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Southwest Illinois right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.