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Hotels in Southwest Illinois

Choose from 639 Southwest Illinois Hotel Deals

Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. Vernon
3 out of 5
145 North 44th Street , Mount Vernon, IL
  • 2 hours drive from Southern Illinois University
The price is $117 per night from Apr 6 to Apr 7
$117
includes taxes & fees
Apr 6 - Apr 7
Stay at this 3-star business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,258 reviews)
"The staff was exceptionally kind. The hotel offered complimentary drinks and very generous dinner buffet. The indoor pool has hot tub with outdoor pool as well. I was so tired when arrived tonight it was a pleasure to find a fabulous hotel"

Reviewed on Mar 18, 2025

Drury Plaza Hotel Mt. Vernon
Super 8 by Wyndham O'Fallon
Super 8 by Wyndham O'Fallon
2 out of 5
1100 Eastgate Dr, O'Fallon, IL
  • 3 hours drive from Southern Illinois University
The price is $60 per night from Mar 25 to Mar 26
$60
includes taxes & fees
Mar 25 - Mar 26
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.6/10 Good! (1,002 reviews)
Great hotel.
"Excellent service. Excellent value."

Reviewed on Mar 15, 2025

Super 8 by Wyndham O'Fallon
Red Lion Inn & Suites Pontoon Beach
Red Lion Inn & Suites Pontoon Beach
2.5 out of 5
1240 E Chain Of Rocks Rd, Granite City, IL
  • 3 hours drive from Southern Illinois University
The price is $70 per night from Mar 24 to Mar 25
$70
includes taxes & fees
Mar 24 - Mar 25
Stay at this hotel in Granite City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
8/10 Very Good! (291 reviews)
"My trip was really comfortable and relaxing. I stayed here solo. Good cable convenient location good breakfast and very comfortable and quiet"

Reviewed on Mar 16, 2025

Red Lion Inn & Suites Pontoon Beach
Drury Inn & Suites St. Louis O'Fallon, IL
Drury Inn & Suites St. Louis O'Fallon, IL
3 out of 5
1118 Central Park Drive, O'Fallon, IL
  • 3 hours drive from Southern Illinois University
The price is $125 per night from Mar 30 to Mar 31
$125
includes taxes & fees
Mar 30 - Mar 31
Stay at this 3-star business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,002 reviews)
"Safety and great parking"

Reviewed on Mar 15, 2025

Drury Inn & Suites St. Louis O'Fallon, IL
Walker's Bluff Casino Resort
Walker's Bluff Casino Resort
4.5 out of 5
777 Walkers Bluff Way, Carterville, IL
  • 19 min drive from Southern Illinois University
The price is $144 per night from Mar 23 to Mar 24
$144
includes taxes & fees
Mar 23 - Mar 24
Stay at this 4.5-star luxury resort in Carterville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (295 reviews)
"Very friendly staff and clean."

Reviewed on Mar 10, 2025

Walker's Bluff Casino Resort
Drury Inn & Suites St. Louis Fairview Heights
Drury Inn & Suites St. Louis Fairview Heights
3 out of 5
12 Ludwig Dr, Fairview Heights, IL
  • 3 hours drive from Southern Illinois University
The price is $115 per night from Mar 30 to Mar 31
$115
includes taxes & fees
Mar 30 - Mar 31
Book a stay at this business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,003 reviews)
"Friendly staff, excellent customer service! I always enjoy the breakfast buffet and the evening "Kick-Back""

Reviewed on Mar 10, 2025

Drury Inn & Suites St. Louis Fairview Heights
Quality Inn & Suites near St. Louis and I-255
Quality Inn & Suites near St. Louis and I-255
2.5 out of 5
1607 Pontiac Dr, East St. Louis, IL
  • 3 hours drive from Southern Illinois University
The price is $71 per night from Mar 25 to Mar 26
$71
includes taxes & fees
Mar 25 - Mar 26
Book a stay at this business-friendly hotel in East St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
7.4/10 Good! (1,001 reviews)
"Very polite staff!"

Reviewed on Mar 17, 2025

Quality Inn & Suites near St. Louis and I-255
Baymont by Wyndham Marion
Baymont by Wyndham Marion
2.5 out of 5
2608 W Main St, Marion, IL
  • 43 min drive from Southern Illinois University
The price is $99 per night from Apr 6 to Apr 7
$99
includes taxes & fees
Apr 6 - Apr 7
Book a stay at this business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (1,000 reviews)
"Super friendly staff!!"

Reviewed on Mar 16, 2025

Baymont by Wyndham Marion
Red Lion Inn & Suites Caseyville
Red Lion Inn & Suites Caseyville
2 out of 5
8950 Tucker Dr, Caseyville, IL
  • 3 hours drive from Southern Illinois University
The price is $60 per night from Mar 23 to Mar 24
$60
includes taxes & fees
Mar 23 - Mar 24
Stay at this motel in Caseyville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Pleasant Ridge Park and Cahokia Mounds State Historic ...
5.4/10 (181 reviews)
"It was good and newly built no issues"

Reviewed on Mar 13, 2025

Red Lion Inn & Suites Caseyville
Drury Inn & Suites Marion
Drury Inn & Suites Marion
3 out of 5
2706 W DeYoung St, Marion, IL
  • 42 min drive from Southern Illinois University
The price is $130 per night from Apr 6 to Apr 7
$130
includes taxes & fees
Apr 6 - Apr 7
Stay at this 3-star business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,000 reviews)
"We were absolutely blown way by the hospitality of the staff - the bartender and the woman that checked us in AND made our pancakes was amazing. We thought they acted like it was their own small business. Additionally the margaritas were amazing, as was the pulled pork. This was our first stay at ..."

Reviewed on Mar 5, 2025

Drury Inn & Suites Marion
Best Western Plus Pontoon Beach
Best Western Plus Pontoon Beach
3 out of 5
4 Regency Pkwy, Granite City, IL
  • 3 hours drive from Southern Illinois University
The price is $105 per night from Apr 7 to Apr 8
$105
includes taxes & fees
Apr 7 - Apr 8
Stay at this 3-star business-friendly hotel in Granite City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (590 reviews)
"Nope"

Reviewed on Mar 15, 2025

Best Western Plus Pontoon Beach
La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
2.5 out of 5
136 Regency Park, O'Fallon, IL
  • 3 hours drive from Southern Illinois University
The price is $68 per night from Mar 25 to Mar 26
$68
includes taxes & fees
Mar 25 - Mar 26
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6.4/10 (1,008 reviews)
"I was very pleased with the room, it was very clean and quiet. The hallways were in serious need of some cleaning. Breakfast could have used some variety. Same thing all three days."

Reviewed on Mar 3, 2025

La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Southwest Illinois

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How many hotels are there in Southwest Illinois?

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