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Featured Luxury Southwest Illinois
Super 8 by Wyndham Troy IL/St. Louis Area
910 Edwardsville Rd, Troy, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Troy. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Super 8 by Wyndham Mt. Vernon IL
401 S 44th St, Mount Vernon, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Super 8 by Wyndham Carbondale
1180 E Main St, Carbondale, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly motel in Carbondale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Super 8 by Wyndham O'Fallon
1100 Eastgate Dr, O'Fallon, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Super 8 by Wyndham Fairview Heights-St. Louis
45 Ludwig Dr, Fairview Heights, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our ...
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
6 Gateway Dr, Collinsville, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Collinsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Super 8 by Wyndham Salem
118 Woods Lane, I-57 and US 50 West, Salem, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly motel in Salem. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Americas Best Value Inn West Frankfort
1001 Factory Outlet Blvd, West Frankfort, IL
Fully refundableReserve now, pay when you stay
Stay at this motel in West Frankfort. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Country Inn & Suites by Radisson, Marion, IL
1306 Halfway Road, Marion, IL
Fully refundable
Book a stay at this business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Days Inn by Wyndham Collinsville/St. Louis
12 Commerce Drive, I-55/70 and IL 157, Collinsville, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Collinsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Comfort Suites Mount Vernon
404 South 44th Street, Mount Vernon, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
DoubleTree by Hilton Collinsville - St. Louis
1000 Eastport Plaza Dr, Collinsville, IL
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Collinsville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the property condition ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options in Southwest Illinois
- Hotels with Free Parking in Southwest Illinois
- Family Hotels in Southwest Illinois
- Pet-friendly Hotels in Southwest Illinois
- Hotels with a Pool in Southwest Illinois
- Hotels with an Indoor Pool in Southwest Illinois
- Historic Hotels in Southwest Illinois
- Hotels with Hot Tubs in Southwest Illinois
- Resorts & Hotels with Spas in Southwest Illinois
- Winery Hotels in Southwest Illinois
- Hotel Wedding Venues in Southwest Illinois
Top Points of Interests in Southwest Illinois
- Hotels near Southern Illinois University
- Hotels near Lake of Egypt
- Hotels near Rend Lake
- Hotels near O'Fallon Family Sports Park
- Hotels near Scott Air Force Base
- Hotels near Marion Cultural and Civic Center
- Hotels near Giant City State Park
- Hotels near Carlyle Lake
- Hotels near DuQuoin State Fairgrounds
- Hotels near Gateway Conference Center
- Hotels near McKendree University
- Hotels near Cahokia Mounds State Historic Site
- Hotels near St. Claire Square Mall
- Hotels near National Shrine of Our Lady of the Snows
- Hotels near World Wide Technology Raceway
- Hotels near St. Clair Bowl
- Hotels near The Gardens at SIUE
- Hotels near The Edge
- Hotels near Southwestern Illinois College
- Hotels near FanDuel Sportsbook and Horse Racing
Cities near Southwest Illinois
- St. Charles Hotels (68.76 mi)
- Paducah Hotels (91.58 mi)
- Ste Genevieve Hotels (37.06 mi)
- Maryland Heights Hotels (62.9 mi)
- Cape Girardeau Hotels (63.87 mi)
- Chesterfield Hotels (67.53 mi)
- Marion Hotels (44.25 mi)
- Mount Vernon Hotels (29.96 mi)
- Carbondale Hotels (36.79 mi)
- O'Fallon Hotels (35.6 mi)
- Bridgeton Hotels (64.13 mi)
- Hazelwood Hotels (63.47 mi)
- Ozarks Hotels (182.52 mi)
- Sikeston Hotels (93.64 mi)
- Metropolis Hotels (83.99 mi)
- Collinsville Hotels (42.26 mi)
- Farmington Hotels (61.53 mi)
- Alton Hotels (60.69 mi)
- Edwardsville Hotels (48.93 mi)
- Fenton Hotels (57.51 mi)
Car Rentals Near Southwest Illinois
- Car rentals in St. Charles
- Car rentals in Paducah
- Car rentals in Ste Genevieve
- Car rentals in Maryland Heights
- Car rentals in Cape Girardeau
- Car rentals in Chesterfield
- Car rentals in Marion
- Car rentals in Mount Vernon
- Car rentals in Carbondale
- Car rentals in O'Fallon
- Car rentals in Bridgeton
- Car rentals in Hazelwood
- Car rentals in Ozarks
- Car rentals in Sikeston
- Car rentals in Metropolis
- Car rentals in Collinsville
Top Luxury Hotel Destinations
- Amarillo Luxury Hotels
- Sioux Falls Luxury Hotels
- Fort Wayne Luxury Hotels
- South Padre Island Luxury Hotels
- Cheyenne Luxury Hotels
- Corpus Christi Luxury Hotels
- Gettysburg Luxury Hotels
- Fresno Luxury Hotels
- Fayetteville Luxury Hotels
- Springfield Luxury Hotels
- Flagstaff Luxury Hotels
- Tuscaloosa Luxury Hotels
- Toledo Luxury Hotels
- Traverse City Luxury Hotels
- Twin Falls Luxury Hotels
- Scranton Luxury Hotels
- Columbia Luxury Hotels
- Catalina Island Luxury Hotels
- Shreveport Luxury Hotels
- Tallahassee Luxury Hotels