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Featured Southwest Illinois Family Hotels

Country Inn & Suites by Radisson, Marion, IL
1306 Halfway Road, Marion, IL
Fully refundable
Book a stay at this business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Drury Plaza Hotel Mt. Vernon
145 North 44th Street , Mount Vernon, IL
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...

Rodeway Inn & Suites
116 Regency Park, O'Fallon, IL
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

Best Western Troy Hotel
2020 Formosa Drive, Troy, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Troy. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...

La Quinta Inn & Suites by Wyndham Pontoon Beach
14 Regency Park Dr, Granite City, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Granite City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

Drury Inn & Suites St. Louis O'Fallon, IL
1118 Central Park Drive, O'Fallon, IL
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
6 Gateway Dr, Collinsville, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Collinsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

Drury Inn & Suites Marion
2706 W DeYoung St, Marion, IL
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Comfort Suites Mount Vernon
404 South 44th Street, Mount Vernon, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...

La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
136 Regency Park, O'Fallon, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...

Super 8 by Wyndham Carbondale
1180 E Main St, Carbondale, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly motel in Carbondale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

Days Inn by Wyndham Collinsville/St. Louis
12 Commerce Drive, I-55/70 and IL 157, Collinsville, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Collinsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels with Pools in Southwest Illinois

Comfort Suites Mount Vernon
404 South 44th Street, Mount Vernon, IL
Book a stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,000 reviews)
"The staff was great and so was breakfast."
Reviewed on Mar 16, 2025

Best Western Marion Hotel
400 Comfort Dr, Marion, IL
Book a stay at this business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,001 reviews)
"Staff was super friendly; comfortable place"
Reviewed on Mar 18, 2025

Drury Plaza Hotel Mt. Vernon
145 North 44th Street , Mount Vernon, IL
Stay at this 3-star business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,258 reviews)
"The staff was exceptionally kind. The hotel offered complimentary drinks and very generous dinner buffet. The indoor pool has hot tub with outdoor pool as well. I was so tired when arrived tonight it was a pleasure to find a fabulous hotel"
Reviewed on Mar 18, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels With Connecting Rooms in Southwest Illinois

Quality Inn & Suites Vandalia near I-70 and Hwy 51
1920 Kennedy Boulevard, Vandalia, IL
Book a stay at this business-friendly hotel in Vandalia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Best Western Marion Hotel
400 Comfort Dr, Marion, IL
Book a stay at this business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Best Western Plus MidAmerica Hotel
9730 Hayden Drive, Mascoutah, IL
Book a stay at this business-friendly hotel in Mascoutah. Enjoy free breakfast, free parking, and a free airport shuttle. Our guests praise the helpful staff ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options
- Hotels with Free Parking in Southwest Illinois
- Pet-friendly Hotels in Southwest Illinois
- Hotels with a Pool in Southwest Illinois
- Hotels with an Indoor Pool in Southwest Illinois
- Historic Hotels in Southwest Illinois
- Hotels with Hot Tubs in Southwest Illinois
- Luxury Hotels in Southwest Illinois
- Resorts & Hotels with Spas in Southwest Illinois
- Winery Hotels in Southwest Illinois
- Hotel Wedding Venues in Southwest Illinois
Top Points of Interests in Southwest Illinois
- Hotels near Southern Illinois University
- Hotels near Lake of Egypt
- Hotels near Scott Air Force Base
- Hotels near Rend Lake
- Hotels near Giant City State Park
- Hotels near O'Fallon Family Sports Park
- Hotels near World Wide Technology Raceway
- Hotels near Carlyle Lake
- Hotels near Cahokia Mounds State Historic Site
- Hotels near The Edge
- Hotels near DuQuoin State Fairgrounds
- Hotels near St. Claire Square Mall
- Hotels near Gateway Conference Center
- Hotels near McKendree University
- Hotels near Ferne Clyffe State Park
- Hotels near Blue Sky Vineyards
- Hotels near Marion Cultural and Civic Center
- Hotels near I-57 Drag Strip
- Hotels near National Shrine of Our Lady of the Snows
- Hotels near Southwestern Illinois College
Cities near Southwest Illinois
- St. Charles Hotels (68.76 mi)
- Paducah Hotels (91.58 mi)
- Maryland Heights Hotels (62.9 mi)
- Chesterfield Hotels (67.53 mi)
- Cape Girardeau Hotels (63.87 mi)
- Marion Hotels (44.25 mi)
- Carbondale Hotels (36.79 mi)
- O'Fallon Hotels (35.6 mi)
- Mount Vernon Hotels (29.96 mi)
- Hazelwood Hotels (63.47 mi)
- Sikeston Hotels (93.64 mi)
- Ste Genevieve Hotels (37.06 mi)
- Collinsville Hotels (42.26 mi)
- Alton Hotels (60.69 mi)
- Fenton Hotels (57.51 mi)
- Fairview Heights Hotels (39.75 mi)
- Metropolis Hotels (83.99 mi)
- Ozarks Hotels (182.52 mi)
- Richmond Heights Hotels (54.8 mi)
- Edwardsville Hotels (48.93 mi)
Car Rentals Near Southwest Illinois
- Car rentals in St. Charles
- Car rentals in Paducah
- Car rentals in Maryland Heights
- Car rentals in Chesterfield
- Car rentals in Cape Girardeau
- Car rentals in Marion
- Car rentals in Carbondale
- Car rentals in O'Fallon
- Car rentals in Mount Vernon
- Car rentals in Hazelwood
- Car rentals in Sikeston
- Car rentals in Ste Genevieve
- Car rentals in Collinsville
- Car rentals in Alton
- Car rentals in Fenton
- Car rentals in Fairview Heights
Top Family Hotel Destinations
- Las Vegas Family Hotels
- Arcade Family Hotels
- Branson Family Hotels
- Biloxi Family Hotels
- Ocean City Family Hotels
- Orlando Family Hotels
- Buffalo Family Hotels
- Reno Family Hotels
- Colorado Springs Family Hotels
- Phoenix Family Hotels
- Niagara Falls Family Hotels
- New York Family Hotels
- Whistler Family Hotels
- Houston Family Hotels
- Fort Walton Beach Family Hotels
- Pensacola Beach Family Hotels
- Tampa Family Hotels
- Myrtle Beach Family Hotels
- Miami Beach Family Hotels
- Birmingham Family Hotels
Top Booked Hotels in Southwest Illinois
- Super 8 by Wyndham O'Fallon
- Red Lion Inn & Suites Pontoon Beach
- Quality Inn & Suites near St. Louis and I-255
- Baymont by Wyndham Marion
- Best Western Plus Pontoon Beach
- La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
- Quality Inn O'Fallon IL - St. Louis
- Comfort Suites Mount Vernon
- Holiday Inn Express & Suites Edwardsville by IHG
- Super 8 by Wyndham Troy IL/St. Louis Area