Hotels Near
East Main Street

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Featured East Main Street Hotels

La Quinta Inn & Suites by Wyndham Grand Junction
La Quinta Inn & Suites by Wyndham Grand Junction
2.5 out of 5
2761 Crossroads Blvd, Grand Junction, CO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Grand Junction. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (2,415 reviews)
"It was ok"

Reviewed on Apr 25, 2025

La Quinta Inn & Suites by Wyndham Grand Junction
Grand Vista Hotel
Grand Vista Hotel
3.5 out of 5
2790 Crossroads Blvd, Grand Junction, CO
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Grand Junction. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the restaurant ...
8.2/10 Very Good! (3,043 reviews)
"This was the perfect place to stay for a night in Grand Junction. Parking was convenient and we were close to the highway, as well as many dining options. The property itself was a bit old and run down, but clean and spacious. It had everything we needed."

Reviewed on Apr 27, 2025

Grand Vista Hotel
Clarion Inn Grand Junction
Clarion Inn Grand Junction
2.5 out of 5
755 Horizon Drive, Grand Junction, CO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Grand Junction. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
8.6/10 Excellent! (1,386 reviews)
"Was nice"

Reviewed on Apr 26, 2025

Clarion Inn Grand Junction
Ramada by Wyndham Grand Junction
Ramada by Wyndham Grand Junction
2.5 out of 5
752 Horizon Dr, I-70 at Exit 31, Grand Junction, CO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Grand Junction. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
8.4/10 Very Good! (1,563 reviews)
"WHAT I DIDNT LIKE WAS THE BREAKFAST - IT WAS COLD WHAT THERE WAS AVAILABLE, AND THEY RAN OUT OF YOGURT AND THE DRINKS ( APPLE jUICE) WAS WARM"

Reviewed on Apr 28, 2025

Ramada by Wyndham Grand Junction
Wine Country Inn Palisade
Wine Country Inn Palisade
3.5 out of 5
777 Grande River Drive, Palisade, CO
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Palisade. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in ...
9.6/10 Exceptional! (1,004 reviews)
"Wine Country Inn is one of the best hotels we have ever stayed in. We are in Palisade 2-3 times per year and we always try to stay at this hotel. Everything from the staff to the beds to the outdoor areas are perfect. You will not be disappointed with anything!"

Reviewed on Apr 27, 2025

Wine Country Inn Palisade
Doubletree Hotel Grand Junction
Doubletree Hotel Grand Junction
4 out of 5
743 Horizon Dr, Grand Junction, CO
Fully refundableReserve now, pay when you stay
Stay at this 4-star family-friendly hotel in Grand Junction. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff ...
8/10 Very Good! (1,004 reviews)
Nice spot
"Excellent service, cleanliness and as an added benefit a good restaurant."

Reviewed on Apr 27, 2025

Doubletree Hotel Grand Junction
Super 8 by Wyndham Grand Junction Colorado
Super 8 by Wyndham Grand Junction Colorado
2 out of 5
728 Horizon Drive, Grand Junction, CO
Fully refundableReserve now, pay when you stay
Stay at this hotel in Grand Junction. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.4/10 Good! (1,002 reviews)
"Front desk staff was great"

Reviewed on Apr 20, 2025

Super 8 by Wyndham Grand Junction Colorado
La Quinta Inn & Suites by Wyndham Fruita
La Quinta Inn & Suites by Wyndham Fruita
2.5 out of 5
570 Raptor Rd, Fruita, CO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Fruita. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (1,005 reviews)
"Very nice property. Clean. Easy to access from the freeway with many dining choices nearby. Good breakfast. Great dog park nearby-just on the other side of the Dinosaur Museum which is next door."

Reviewed on Apr 25, 2025

La Quinta Inn & Suites by Wyndham Fruita
Comfort Inn & Suites
Comfort Inn & Suites
2.5 out of 5
400 Jurassic Ave, Fruita, CO
Fully refundableReserve now, pay when you stay
Book a stay at this golf hotel in Fruita. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.4/10 Very Good! (1,005 reviews)
"Good service. Clean and welcoming."

Reviewed on Apr 26, 2025

Comfort Inn & Suites
Hotel Maverick
Hotel Maverick
4 out of 5
840 Kennedy Avenue, Grand Junction, CO
Fully refundableReserve now, pay when you stay
Stay at this 4-star hotel in Grand Junction. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the restaurant and the helpful staff ...
9.6/10 Exceptional! (1,001 reviews)
"Great new option in Grand Junction. Really impressed with the connection to Colorado Mesa University. Great setting."

Reviewed on Apr 27, 2025

Hotel Maverick
Courtyard by Marriott Grand Junction
Courtyard by Marriott Grand Junction
3 out of 5
765 Horizon Drive, Grand Junction, CO
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Grand Junction. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.4/10 Very Good! (1,002 reviews)
"Staff was exceptionally helpful and very kind; at the front desk, and in their Bistro."

Reviewed on Apr 25, 2025

Courtyard by Marriott Grand Junction
Studio 6 Grand Junction, CO
Studio 6 Grand Junction, CO
2 out of 5
704 Horizon Dr, Grand Junction, CO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly motel in Grand Junction. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
7.4/10 Good! (1,007 reviews)
"Everything was very nice, nothing fancy but clean. Staff was very nice. Convenient location to walk to restaurants."

Reviewed on Apr 25, 2025

Studio 6 Grand Junction, CO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in East Main Street

Grand Junction is a city that has a lot going on, but you have your sights set on East Main Street. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that East Main Street has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of East Main Street hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Grand Junction so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the East Main Street underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the East Main Street city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of East Main Street cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in East Main Street at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $64
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the East Main Street hotel you want, book it, and never look back. Because your great escape is ahead of you.