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Featured Florence Family Hotels

Baymont by Wyndham Florence/Muscle Shoals
115 Ana Drive, Florence, AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property ...

Comfort Suites Florence Shoals Area
140 Matthew Paul Ct, Florence, AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites
1934 Highway 20, Tuscumbia, AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Tuscumbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

Renaissance Shoals Resort and Spa
10 Hightower Place, Florence, AL
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star spa resort in Florence. Enjoy free parking, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...

Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals
1852 Highway 72 E, Tuscumbia, AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Tuscumbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG
180 Etta Gray Street, Florence, AL
Fully refundable
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Quality Inn Florence Muscle Shoals
150 Etta Gray Drive, Florence, AL
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

Lake View Inn & Suites
101 Highway 72, Killen, AL
Stay at this hotel in Killen. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Shoals Golf Club and Blackberry Trail Golf Course are located ...

Red Roof Inn Muscle Shoals
2807 Woodward Ave, Muscle Shoals, AL
Fully refundableReserve now, pay when you stay
Stay at this hotel in Muscle Shoals. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Fame Recording Studios and Tennessee Valley ...

Best Western Plus Russellville Hotel & Suites
13770 Highway 43, Russellville, AL
Fully refundableReserve now, pay when you stay
Stay at this hotel in Russellville. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the helpful staff in our reviews. Popular ...

Comfort Inn & Suites Tuscumbia - Muscle Shoals
5101 Hwy 43 S, Tuscumbia, AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Tuscumbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Alabama Music Hall of Fame and ...

Econo Lodge
13600 Highway 43, Russellville, AL
Fully refundableReserve now, pay when you stay
Stay at this motel in Russellville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Eastside Park and Hal Kirby Jr. Park are located ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels with Pools in Florence

Renaissance Shoals Resort and Spa
10 Hightower Place, Florence, AL
Stay at this 3.5-star spa resort in Florence. Enjoy free parking, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (698 reviews)
"The room was decent"
Reviewed on Apr 21, 2025

Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites
1934 Highway 20, Tuscumbia, AL
Book a stay at this business-friendly hotel in Tuscumbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (558 reviews)
"I loved how clean the staff kept the property. The friendliness of the entire staff and the breakfast was great too"
Reviewed on Apr 27, 2025

Comfort Suites Florence Shoals Area
140 Matthew Paul Ct, Florence, AL
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (676 reviews)
Will stay here again!
"Hotel was very clean. Comfortable beds and a good breakfast variety."
Reviewed on Apr 28, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels With Connecting Rooms in Florence

Lake View Inn & Suites
101 Highway 72, Killen, AL
Stay at this hotel in Killen. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Shoals Golf Club and Blackberry Trail Golf Course are located ...

Baymont by Wyndham Florence/Muscle Shoals
115 Ana Drive, Florence, AL
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property ...

Best Western Plus Russellville Hotel & Suites
13770 Highway 43, Russellville, AL
Stay at this hotel in Russellville. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the helpful staff in our reviews. Popular ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options
- Hotels with Free Parking in Florence
- Hotels with a Pool in Florence
- Pet-friendly Hotels in Florence
- Hotels with Hot Tubs in Florence
- Hotel Wedding Venues in Florence
- Historic Hotels in Florence
- Resorts & Hotels with Spas in Florence
- Hotels with an Indoor Pool in Florence
- Hotels with smoking rooms in Florence
- Luxury Hotels in Florence
Top Points of Interests in Florence
- Hotels near University of North Alabama
- Hotels near Blackberry Trail Golf Course
- Hotels near Renaissance Tower
- Hotels near Key Cave National Wildlife Refuge
- Hotels near Shoals Conference Center
- Hotels near Kennedy-Douglass Center for the Arts
- Hotels near Regency Square Mall
- Hotels near Larimore Home
- Hotels near Shoals Community Theater
- Hotels near Children's Museum of the Shoals
- Hotels near River Heritage Park
- Hotels near Pope's Tavern Museum
- Hotels near Deibert Park
- Hotels near Indian Mound and Museum
- Hotels near W.C. Handy Home
Cities near Florence
- Gulf Coast Hotels (433.21 mi)
- Athens Hotels (40.01 mi)
- Muscle Shoals Hotels (4.19 mi)
- Killen Hotels (9.04 mi)
- Tuscumbia Hotels (4.95 mi)
- Lawrenceburg Hotels (36.18 mi)
- Savannah Hotels (43.67 mi)
- Southeastern United States Hotels (248.96 mi)
- Iuka Hotels (29.08 mi)
- Counce Hotels (37.68 mi)
- Russellville Hotels (20.37 mi)
- North Alabama Hotels (59.61 mi)
- Pickwick Dam Hotels (35.68 mi)
- Rogersville Hotels (21.76 mi)
- Sheffield Hotels (2.69 mi)
- Middle Tennessee Hotels (96.02 mi)
- Waterloo Hotels (23.4 mi)
- Waynesboro Hotels (36.21 mi)
- Northeast Alabama Hotels (80.68 mi)
- Town Creek Hotels (17.43 mi)
Car Rentals Near Florence
- Car rentals in Gulf Coast
- Car rentals in Athens
- Car rentals in Muscle Shoals
- Car rentals in Killen
- Car rentals in Tuscumbia
- Car rentals in Lawrenceburg
- Car rentals in Savannah
- Car rentals in Southeastern United States
- Car rentals in Iuka
- Car rentals in Counce
- Car rentals in Russellville
- Car rentals in North Alabama
- Car rentals in Pickwick Dam
- Car rentals in Rogersville
- Car rentals in Sheffield
- Car rentals in Middle Tennessee
Top Family Hotel Destinations
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- Fort Walton Beach Family Hotels
- Pensacola Beach Family Hotels
- Tampa Family Hotels
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- Birmingham Family Hotels
Top Booked Hotels in Florence
- Renaissance Shoals Resort and Spa
- Comfort Suites Florence Shoals Area
- The Stricklin Hotel
- Baymont by Wyndham Florence/Muscle Shoals
- Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG
- Hampton Inn Florence Midtown near University of North Alabama
- Residence Inn Florence Marriott
- Hampton Inn & Suites Florence-Downtown
- GunRunner Boutique Hotel
- Clarion Inn Sheffield Muscle Shoals
- Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals
- Days Inn by Wyndham Muscle Shoals Florence
- Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites
- The ColdWater Inn
- Hampton Inn Pickwick Dam-At Shiloh Falls