Hotels Near
Main South

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Featured Main South Hotels

Motel 6 Framingham, MA - Boston West

Motel 6 Framingham, MA - Boston West

2 out of 5
1668 Worcester Rd, Framingham, MA
Fully refundable
Stay at this motel in Framingham. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
6.6/10 (1,041 reviews)
"I liked the big bathtub and the super comfortable bed. Thank you!"

Reviewed on Sep 20, 2025

Motel 6 Framingham, MA - Boston West
DoubleTree by Hilton Hotel Boston - Westborough

DoubleTree by Hilton Hotel Boston - Westborough

4 out of 5
5400 Computer Dr, Westborough, MA
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Westborough. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,033 reviews)
"The room was lovely and so clean. I wish we had had more time. Lovely facility"

Reviewed on Sep 22, 2025

DoubleTree by Hilton Hotel Boston - Westborough
Best Western Royal Plaza Hotel & Trade Center

Best Western Royal Plaza Hotel & Trade Center

3 out of 5
181 Boston Post Rd W, Marlborough, MA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Marlborough. Enjoy free breakfast, free parking, and 2 restaurants. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (1,018 reviews)
"The staff were amazing and the amenities were extensive. From a buffet style breakfast that is better than most hotels, and the bar/restaurant open on weekends. Parts were under renovation but everything was clean. I got a standard king size room that was spacious had places to sit and plenty of ..."

Reviewed on Sep 22, 2025

Best Western Royal Plaza Hotel & Trade Center
Wellsworth Hotel

Wellsworth Hotel

3 out of 5
14 Mechanic St, Southbridge, MA
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Southbridge. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the pool and the helpful staff ...
9/10 Wonderful! (1,313 reviews)
"great"

Reviewed on Sep 22, 2025

Wellsworth Hotel
Publick House Historic Inn and Country Motor Lodge

Publick House Historic Inn and Country Motor Lodge

2.5 out of 5
277 Main Street (RT 131), Sturbridge, MA
Fully refundableReserve now, pay when you stay
Book a stay at this spa resort in Sturbridge. Enjoy free parking, an outdoor pool, and a full-service spa. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,525 reviews)
"Our room was really dated and there was a wedding here so it was a lot of partying going on in the middle of the night"

Reviewed on Sep 21, 2025

Publick House Historic Inn and Country Motor Lodge
Sonesta Select Boston Milford

Sonesta Select Boston Milford

3 out of 5
10 Fortune Blvd, Milford, MA
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Milford. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...
8.2/10 Very Good! (1,010 reviews)
"Room was clean, staff was very nice . Only complaint grounds were very dirty lots of trash. Nice fire pit"

Reviewed on Sep 16, 2025

Sonesta Select Boston Milford
Comfort Inn Auburn - Worcester

Comfort Inn Auburn - Worcester

2.5 out of 5
426 Southbridge St, Auburn, MA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Auburn. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.6/10 Good! (1,020 reviews)
"Okay"

Reviewed on Sep 23, 2025

Comfort Inn Auburn - Worcester
Hilton Garden Inn Boston/Marlborough

Hilton Garden Inn Boston/Marlborough

3 out of 5
170 Forest St, Marlborough, MA
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Marlborough. Enjoy breakfast (surcharge), room service, and a fitness center. Our guests praise the helpful staff ...
9.2/10 Wonderful! (1,016 reviews)
"First time staying at this hotel and we will definitely stay again. The hotel was quiet, plenty of parking and nice facilities. Rooms were neat and clean. Restaurant was nice. Only complaint was that the hotel bar closed at 10pm on Saturday night. Should be open later."

Reviewed on Sep 21, 2025

Hilton Garden Inn Boston/Marlborough
Courtyard by Marriott Boston Marlborough

Courtyard by Marriott Boston Marlborough

3 out of 5
75 Felton St, Marlborough, MA
Stay at this 3-star business-friendly hotel in Marlborough. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,006 reviews)
"Room was clean and spacious. I wish the fridge was a little bit bigger, but ice machine was conveniently located on the same floor. Staff was kind and helpful. Would recommend."

Reviewed on Sep 21, 2025

Courtyard by Marriott Boston Marlborough
Embassy Suites by Hilton Boston Marlborough

Embassy Suites by Hilton Boston Marlborough

3.5 out of 5
123 Boston Post Rd W, Marlborough, MA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Marlborough. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,009 reviews)
"You get a good continental breakfast plus theres an omelet station allowing the guest to choose the fillings, the staff were all warm and welcoming, Shopra ( not sure if I got it right ) in the breakfast stop by in our table asking us how were doing , which is very nice and accommodating, I would ..."

Reviewed on Sep 18, 2025

Embassy Suites by Hilton Boston Marlborough
Hampton Inn Boston/Marlborough

Hampton Inn Boston/Marlborough

2.5 out of 5
277 Boston Post Rd West, Marlborough, MA
Fully refundableReserve now, pay when you stay
Stay at this hotel in Marlborough. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,018 reviews)
"Only concern was that room service was not daily. Also other guests there were very loud. Doors were slamming, lots of noise overnight. Based on the noise, I’m not sure I would stay here again. But everything else was good."

Reviewed on Sep 22, 2025

Hampton Inn Boston/Marlborough
Extended Stay America Suites Boston Westborough Computer Dr

Extended Stay America Suites Boston Westborough Computer Dr

2.5 out of 5
1800 Computer Dr, Westborough, MA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Westborough. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
6.4/10 (949 reviews)
"I would like a cafeteria eith better options to eat."

Reviewed on Sep 7, 2025

Extended Stay America Suites Boston Westborough Computer Dr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Main South

Worcester is a city that has a lot going on, but you have your sights set on Main South. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Main South has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Main South hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Worcester so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Main South underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Main South city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Main South cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Main South at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $94
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Main South hotel you want, book it, and never look back. Because your great escape is ahead of you.