Search Deals onMayo Clinic Florida Vacation Packages
Photo by Amber Palmer
Mayo Clinic Florida Flight + Hotel Packages
Price found within the past 48 hours. Click for updated prices.

Hyatt Regency Jacksonville
Save 100% on your flight
Price was $569, price is now $438 per person
$438
per person
Oct 22 - Oct 26
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Jacksonville (JAX)
Stay at this 4-star eco-certified hotel in Jacksonville. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions EverBank Stadium and Jacksonville Zoo and Gardens are located nearby.

Hampton Inn Jacksonville Beach/Oceanfront
Save 100% on your flight
Price was $1,175, price is now $817 per person
$817
per person
Oct 29 - Nov 4
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Jacksonville (JAX)
Stay at this 3-star beach hotel in Jacksonville Beach. Enjoy free breakfast, 2 outdoor pools, and a beach locale. Our guests praise the breakfast and the pool in our reviews. Popular attractions Sleiman North Shopping Center and Jacksonville Beach Pier are located nearby.

DoubleTree by Hilton Hotel Jacksonville Riverfront
Save 100% on your flight
Price was $1,013, price is now $714 per person
$714
per person
Oct 29 - Nov 4
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Jacksonville (JAX)
Stay at this 4-star hotel in Jacksonville. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff in our reviews. Popular attractions EverBank Stadium and Jacksonville Zoo and Gardens are located nearby.

Delta Hotels by Marriott Jacksonville Deerwood
Save 100% on your flight
Price was $709, price is now $505 per person
$505
per person
Oct 29 - Nov 4
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Jacksonville (JAX)
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free parking, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions St. Johns Town Center and EverBank Stadium are located nearby.

Hammock Beach Golf Resort & Spa
Save 100% on your flight
Price was $1,306, price is now $969 per person
$969
per person
Oct 24 - Oct 28
found 1 day ago
Roundtrip non-stop flight included
Allentown (ABE) to Daytona Beach (DAB)
Stay at this 4-star luxury resort in Palm Coast. Enjoy free WiFi, free parking, and 9 outdoor pools. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Ocean Hammock Golf Club and Hammock Beach Ocean Course are located nearby.

Landing Jacksonville
Save 100% on your flight
Price was $876, price is now $667 per person
$667
per person
Oct 29 - Nov 4
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Jacksonville (JAX)
Stay at this 4-star aparthotel in Jacksonville. Enjoy free parking, a fitness center, and daily housekeeping. Popular attractions EverBank Stadium and Jacksonville Zoo and Gardens are located nearby.

The Ritz-Carlton, Amelia Island
Save 100% on your flight
Price was $2,989, price is now $2,288 per person
$2,288
per person
Oct 29 - Nov 4
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Jacksonville (JAX)
Stay at this 5-star luxury resort in Fernandina Beach. Enjoy a full-service spa, a beach locale, and a golf course. Our guests praise the property condition in our reviews. Popular attractions Peters Point Beachfront Park and Palmetto Walk Shopping Village are located nearby.

Home2 Suites by Hilton Jacksonville-South/St. Johns Town Ctr
Save 100% on your flight
Price was $751, price is now $578 per person
$578
per person
Oct 29 - Nov 4
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Jacksonville (JAX)
Stay at this 3-star business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff in our reviews. Popular attractions St. Johns Town Center and Topgolf are located nearby.

Comfort Inn & Suites Jacksonville - Orange Park Near Naval Air Station
Save 100% on your flight
Price was $673, price is now $518 per person
$518
per person
Oct 29 - Nov 4
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Jacksonville (JAX)
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Orange Park Mall and Westside Regional Park are located nearby.

Omni Amelia Island Resort & Spa
Save 100% on your flight
Price was $1,854, price is now $1,431 per person
$1,431
per person
Oct 29 - Nov 4
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Jacksonville (JAX)
Stay at this 4-star beach resort in Fernandina Beach. Enjoy free WiFi, 2 outdoor pools, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular attractions Amelia Island Nature Center and Segway of Amelia Island are located nearby.

Casa Marina Hotel
Save 100% on your flight
Price was $801, price is now $620 per person
$620
per person
Oct 29 - Nov 4
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Jacksonville (JAX)
Stay at this 3-star hotel in Jacksonville Beach. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the bar in our reviews. Popular attractions Jacksonville Beach Pier and Northeast Florida Beaches are located nearby.

Amelia Hotel at the Beach
Save 100% on your flight
Price was $634, price is now $495 per person
$495
per person
Oct 29 - Nov 4
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Jacksonville (JAX)
Book a stay at this eco-certified hotel in Fernandina Beach. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant in our reviews. Popular attractions Seaside Park and Fernandina Beach Pinball Museum are located nearby.
3-4 Night Vacations in Mayo Clinic Florida
Price found within the past 48 hours. Click for updated prices.



5-7 Night Vacations in Mayo Clinic Florida
Price found within the past 48 hours. Click for updated prices.



Mayo Clinic Florida Last Minute Hotel Deals

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
14390 Mayo Boulevard, Jacksonville, FL
Stay at this 3-star business-friendly hotel in Jacksonville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
4905 SAN PABLO ROAD SOUTH, Jacksonville, FL
Stay at this 3-star business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

Hilton Jacksonville At Mayo Clinic
4745 Transformation Way, Jacksonville, FL
Stay at this 4.5-star luxury hotel in Jacksonville. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions St. Johns Town Center and TPC ...

Margaritaville Jacksonville Beach
715 1st St N, Jacksonville Beach, FL
Book a stay at this beach hotel in Jacksonville Beach. Enjoy free WiFi, a beach locale, and breakfast (surcharge). Our guests praise the pool and the bar in ...

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
4791 Windsor Commons Ct, Jacksonville, FL
Book a stay at this golf hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our ...

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
13733 Beach Blvd, Jacksonville, FL
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...

TownePlace Suites by Marriott Jacksonville East
13741 BEACH BLVD, Jacksonville, FL
Stay at this 3-star business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
1220 Marsh Landing Pkwy, Jacksonville Beach, FL
Book a stay at this business-friendly hotel in Jacksonville Beach. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover Other Travel Deals
- Legoland Florida
- Universal Studios Hollywood®
- Legoland California
- Broadway New York
- The Wizarding World of Harry Potter
- Sanibel Captiva Island
- Paseo de España
- Universal Studios Florida
- San Antonio SeaWorld
- Siargao Island
- Australia Zoo
- Busch Gardens Tampa Bay
- SeaWorld® Orlando
- Tolantongo Caves
- Eleuthera and Harbour Island
- Biltmore Estate
- Blue Lagoon
- Swiss Alps
- Silver Dollar City
- Lackland Air Force Base
- Grand Teton National Park
- San Diego Zoo
- Holy Land Experience
- Grand Ole Opry
- Ark Encounter
- Levi's Stadium
- Breckenridge Ski Resort
- Alcatraz Island
- Six Flags Magic Mountain
- Walt Disney World®
- Dollywood
- Kalahari Waterpark Resort
- Giza Pyramid Complex
- Casino at Don Laughlin's Riverside Resort
- Hoover Dam
- Hollywood Beach
- Faisalabad Clock Tower
- Venice Beach Boardwalk
- Blue Lagoon Beach
- Moraine Lake
- Hotels with a Pool in Jacksonville
- Apartment Hotel in Jacksonville
- Family Hotels in Jacksonville
- Beach Hotels in Jacksonville
- Hotels with Free Parking in Jacksonville
- Pet-friendly Hotels in Jacksonville
- Romantic Hotels in Jacksonville
- Hotel Wedding Venues in Jacksonville
- Hotels with Hot Tubs in Jacksonville
- Luxury Hotels in Jacksonville
- St. Augustine Hotels
- Jacksonville Beach Hotels
- Fernandina Beach Hotels
- Amelia Island Hotels
- Ponte Vedra Beach Hotels
- Atlantic Beach Hotels
- Orange Park Hotels
- Neptune Beach Hotels
- St. Johns Hotels
- Fleming Island Hotels
- Ponte Vedra Hotels
- Green Cove Springs Hotels
- Southeastern United States Hotels
- Northern Florida Hotels
- Northeast Florida Hotels
- Whites Ford Hotels