Search for Cheap Deals on
Kid-Friendly Hotels in Mesopotamia

Check Last Minute Mesopotamia Hotel Deals

Tonight Apr 13 - Apr 14Next weekend Apr 18 - Apr 20

You choose what matters — star rating, location, amenities.

We pick the perfect hotel, packed with all your must-haves.

Your hotel is revealed right after booking!

Featured Mesopotamia Family Hotels

Hotel das Cataratas, A Belmond Hotel, Iguassu Falls
Hotel das Cataratas, A Belmond Hotel, Iguassu Falls
5 out of 5
Rodovia Br 469 Km 32, Iguassu National Park, Foz do Iguaçu, PR
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Foz do Iguaçu. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff and the property ...
Hotel das Cataratas, A Belmond Hotel, Iguassu Falls
Loi Suites Iguazú Hotel
Loi Suites Iguazú Hotel
5 out of 5
Selva Iriapu Sin Numero, Casilla de Correo 11, Puerto Iguazú, Misiones
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury resort in Puerto Iguazú. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our ...
Loi Suites Iguazú Hotel
Amérian Portal del Iguazú Hotel
Amérian Portal del Iguazú Hotel
4 out of 5
Avenida 3 Fronteras 780, Puerto Iguazú, Misiones
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa resort in Puerto Iguazú. Enjoy free breakfast, free parking, and a full-service spa. Popular attractions Triple Frontier and Cataratas ...
Amérian Portal del Iguazú Hotel
Iguazú Jungle Lodge
Iguazú Jungle Lodge
3.5 out of 5
Avenida Hipolito Irigoyen s/n, Puerto Iguazú, Misiones
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star family-friendly inn in Puerto Iguazú. Enjoy free breakfast, free WiFi, and room service. Our guests praise the restaurant and the helpful ...
Iguazú Jungle Lodge
Hotel Colonial Iguaçu
Hotel Colonial Iguaçu
3.5 out of 5
Rod. das Cataratas, Km 20, Parque Nacional do Iguacu, Foz do Iguaçu, PR
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star family-friendly hotel in Foz do Iguaçu. Enjoy free WiFi, free parking, and room service. Popular attractions Entrance to the Iguassu Falls ...
Hotel Colonial Iguaçu
Hotel Saint George
Hotel Saint George
4 out of 5
Avenida Cordoba 148, Puerto Iguazú, Misiones
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa hotel in Puerto Iguazú. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
Hotel Saint George
Exe Hotel Cataratas
Exe Hotel Cataratas
5 out of 5
Ruta Nacional 12 km 4, Iguacu National Park, Puerto Iguazú, Misiones
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Puerto Iguazú. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Triple Frontier and Cataratas Avenue ...
Exe Hotel Cataratas
Gran Melia Iguazú
Gran Melia Iguazú
5 out of 5
Parque Nacional Iguazu, Puerto Iguazú, Misiones
Fully refundableReserve now, pay when you stay
Book a stay at this luxury hotel in Puerto Iguazú. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property condition ...
Gran Melia Iguazú
Tupa apart
Tupa apart
3 out of 5
Cocú 695, Puerto Iguazú, Misiones
Stay at this 3-star hotel in Puerto Iguazú. Enjoy free WiFi, free parking, and daily housekeeping. Popular attractions Triple Frontier and Cataratas Avenue are ...
Tupa apart
Iguazu Grand Resort Spa & Casino
Iguazu Grand Resort Spa & Casino
5 out of 5
Route 12 Km 1640, Puerto Iguazú, Misiones
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Puerto Iguazú. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
Iguazu Grand Resort Spa & Casino
La Reserva Virgin Lodge
La Reserva Virgin Lodge
4 out of 5
Ruta 12 km 5, Puerto Iguazú, Misiones
Fully refundableReserve now, pay when you stay
Stay at this 4-star boutique hotel in Puerto Iguazú. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
La Reserva Virgin Lodge
Amérian Hotel Casino Gala
Amérian Hotel Casino Gala
4 out of 5
Juan Domingo Perón 330 esq. Necochea, Resistencia, Chaco
Fully refundableReserve now, pay when you stay
Stay at this 4-star hotel in Resistencia. Enjoy free breakfast, free WiFi, and a casino. Popular attractions Amérian Hotel Casino Gala and Professor L. Herrera ...
Amérian Hotel Casino Gala
See all 430 properties in Mesopotamia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels with Pools in Mesopotamia

Loi Suites Iguazú Hotel
Loi Suites Iguazú Hotel
5 out of 5
Selva Iriapu Sin Numero, Casilla de Correo 11, Puerto Iguazú, Misiones
Stay at this 5-star luxury resort in Puerto Iguazú. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our ...
9/10 Wonderful! (999 reviews)
"Immersed in rainforest with high over the river views. After 2 weeks travel, this was just the quiet and relaxing resort property we wanted. Enjoyed spacious room with balcony and seating at the bars and restaurant around number of pools. Staff ranged from satisfactory to outstanding. Not in the ..."

Reviewed on Apr 6, 2025

Loi Suites Iguazú Hotel
Hotel das Cataratas, A Belmond Hotel, Iguassu Falls
Hotel das Cataratas, A Belmond Hotel, Iguassu Falls
5 out of 5
Rodovia Br 469 Km 32, Iguassu National Park, Foz do Iguaçu, PR
Stay at this 5-star luxury hotel in Foz do Iguaçu. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff and the property ...
9.8/10 Exceptional! (998 reviews)
"Great location for Iguassu Falls visit. Rooms were great and the food was excellent!"

Reviewed on Apr 7, 2025

Hotel das Cataratas, A Belmond Hotel, Iguassu Falls
La Reserva Virgin Lodge
La Reserva Virgin Lodge
4 out of 5
Ruta 12 km 5, Puerto Iguazú, Misiones
Stay at this 4-star boutique hotel in Puerto Iguazú. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
8.4/10 Very Good! (781 reviews)
"Very nice hotel and it’s so peaceful! The pool is lovely and the restaurant for breakfast was so good! Easy to travel to the waterfalls and the town of Iguazu is a short drive away. Highly recommend"

Reviewed on Apr 5, 2025

La Reserva Virgin Lodge
See all 430 properties in Mesopotamia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels With Connecting Rooms in Mesopotamia

Amérian Portal del Iguazú Hotel
Amérian Portal del Iguazú Hotel
4 out of 5
Avenida 3 Fronteras 780, Puerto Iguazú, Misiones
Stay at this 4-star spa resort in Puerto Iguazú. Enjoy free breakfast, free parking, and a full-service spa. Popular attractions Triple Frontier and Cataratas ...
Amérian Portal del Iguazú Hotel
Guaminí Misión Hotel
Guaminí Misión Hotel
3.5 out of 5
Av. Río Paraná & Palo Rosa, Puerto Iguazú, Misiones
Stay at this 3.5-star spa hotel in Puerto Iguazú. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Triple Frontier and Cataratas Avenue ...
Guaminí Misión Hotel
Hathor Concordia
Hathor Concordia
3 out of 5
Ruta Nacional 14-km 264.5, Concordia, Entre Rios
Stay at this 3-star business-friendly hotel in Concordia. Enjoy free breakfast, free WiFi, and room service. Popular attractions Concordia Golf Course and Castillo ...
Hathor Concordia
See all 430 properties in Mesopotamia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.