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Featured Mesopotamia Family Hotels

Hotel das Cataratas, A Belmond Hotel, Iguassu Falls
Rodovia Br 469 Km 32, Iguassu National Park, Foz do Iguaçu, PR
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Foz do Iguaçu. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff and the property ...

Loi Suites Iguazú Hotel
Selva Iriapu Sin Numero, Casilla de Correo 11, Puerto Iguazú, Misiones
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury resort in Puerto Iguazú. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our ...

Amérian Portal del Iguazú Hotel
Avenida 3 Fronteras 780, Puerto Iguazú, Misiones
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa resort in Puerto Iguazú. Enjoy free breakfast, free parking, and a full-service spa. Popular attractions Triple Frontier and Cataratas ...

Iguazú Jungle Lodge
Avenida Hipolito Irigoyen s/n, Puerto Iguazú, Misiones
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star family-friendly inn in Puerto Iguazú. Enjoy free breakfast, free WiFi, and room service. Our guests praise the restaurant and the helpful ...

Hotel Colonial Iguaçu
Rod. das Cataratas, Km 20, Parque Nacional do Iguacu, Foz do Iguaçu, PR
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star family-friendly hotel in Foz do Iguaçu. Enjoy free WiFi, free parking, and room service. Popular attractions Entrance to the Iguassu Falls ...

Hotel Saint George
Avenida Cordoba 148, Puerto Iguazú, Misiones
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa hotel in Puerto Iguazú. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff in our reviews. ...

Exe Hotel Cataratas
Ruta Nacional 12 km 4, Iguacu National Park, Puerto Iguazú, Misiones
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Puerto Iguazú. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Cataratas Avenue and Entrance to the ...

Gran Melia Iguazú
Parque Nacional Iguazu, Puerto Iguazú, Misiones
Fully refundableReserve now, pay when you stay
Book a stay at this luxury hotel in Puerto Iguazú. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property condition ...

Tupa apart
Cocú 695, Puerto Iguazú, Misiones
Stay at this 3-star hotel in Puerto Iguazú. Enjoy free WiFi, free parking, and daily housekeeping. Popular attractions Triple Frontier and Cataratas Avenue are ...

Iguazu Grand Resort Spa & Casino
Route 12 Km 1640, Puerto Iguazú, Misiones
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Puerto Iguazú. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...

La Reserva Virgin Lodge
Ruta 12 km 5, Puerto Iguazú, Misiones
Fully refundableReserve now, pay when you stay
Stay at this 4-star boutique hotel in Puerto Iguazú. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...

Amérian Hotel Casino Gala
Juan Domingo Perón 330 esq. Necochea, Resistencia, Chaco
Fully refundableReserve now, pay when you stay
Stay at this 4-star hotel in Resistencia. Enjoy free breakfast, free WiFi, and a casino. Popular attractions Amérian Hotel Casino Gala and Professor L. Herrera ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels with Pools in Mesopotamia

Loi Suites Iguazú Hotel
Selva Iriapu Sin Numero, Casilla de Correo 11, Puerto Iguazú, Misiones
Stay at this 5-star luxury resort in Puerto Iguazú. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our ...
9/10 Wonderful! (999 reviews)
"Hotel in the middle of the jungle! Not walkable but totally worth it. Gorgeous hotel, instagramable open spaces, pleasant staff, good breakfast, great spa and beautiful pool. Rooms are large with scenic balcony but…. Bed not too comfortable and weird smell. Nevertheless, I give it 5 starts!"
Reviewed on May 26, 2025

Hotel das Cataratas, A Belmond Hotel, Iguassu Falls
Rodovia Br 469 Km 32, Iguassu National Park, Foz do Iguaçu, PR
Stay at this 5-star luxury hotel in Foz do Iguaçu. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff and the property ...
9.8/10 Exceptional! (1,000 reviews)
"EVERYTHING Amazing"
Reviewed on May 17, 2025

La Reserva Virgin Lodge
Ruta 12 km 5, Puerto Iguazú, Misiones
Stay at this 4-star boutique hotel in Puerto Iguazú. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
8.4/10 Very Good! (784 reviews)
"Very nice hotel and it’s so peaceful! The pool is lovely and the restaurant for breakfast was so good! Easy to travel to the waterfalls and the town of Iguazu is a short drive away. Highly recommend"
Reviewed on Apr 5, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels With Connecting Rooms in Mesopotamia

Amérian Portal del Iguazú Hotel
Avenida 3 Fronteras 780, Puerto Iguazú, Misiones
Stay at this 4-star spa resort in Puerto Iguazú. Enjoy free breakfast, free parking, and a full-service spa. Popular attractions Triple Frontier and Cataratas ...

Guaminí Misión Hotel
Av. Río Paraná & Palo Rosa, Puerto Iguazú, Misiones
Stay at this 3.5-star spa hotel in Puerto Iguazú. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Triple Frontier and Cataratas Avenue ...

Hathor Concordia
Ruta Nacional 14-km 264.5, Concordia, Entre Rios
Stay at this 3-star business-friendly hotel in Concordia. Enjoy free breakfast, free WiFi, and room service. Popular attractions Concordia Golf Course and Castillo ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options
- Hotels with a Pool in Mesopotamia
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- Casinos in Mesopotamia
- Resorts & Hotels with Spas in Mesopotamia
- Hotels with Hot Tubs in Mesopotamia
- Hotels with smoking rooms in Mesopotamia
- Pet-friendly Hotels in Mesopotamia
- Hotels with an Indoor Pool in Mesopotamia
- Beach Hotels in Mesopotamia
- Apartment Hotel in Mesopotamia
Top Points of Interests in Mesopotamia
- Hotels near El Palmar National Park
- Hotels near Termas de Federacion
- Hotels near Basilica Nuestra Senora De Itati
- Hotels near Termas Concepcion Entrerios
- Hotels near Costanera de Corrientes
- Hotels near Termas Del Ayui
- Hotels near Termas de Chajarí
- Hotels near Portal Carambola
- Hotels near Concepción del Uruguay City Racetrack
- Hotels near Isla Cambacua Beach
- Hotels near Concordia Speedway
- Hotels near Termas de Guaychu
- Hotels near Lago de Salto Grande
- Hotels near Victoria Beach
- Hotels near Termas Federacion Water Park
- Hotels near San José Palace
- Hotels near Santa Rita de Casia Church
- Hotels near Dr. Herminio J. Quiros Park
- Hotels near Castillo San Carlos
- Hotels near Molino Forclaz
Cities near Mesopotamia
- Rosario Hotels (221.16 mi)
- San Pedro Hotels (240.96 mi)
- Campana Hotels (270.37 mi)
- Termas del Arapey Hotels (69.63 mi)
- Posadas Hotels (257.35 mi)
- Encarnacion Hotels (259.99 mi)
- Santa Fe Hotels (158.75 mi)
- Carmelo Hotels (252.81 mi)
- Resistencia Hotels (201.76 mi)
- Uruguaiana Hotels (110.11 mi)
- Corrientes Hotels (196.99 mi)
- Belen de Escobar Hotels (277.04 mi)
- Parana Hotels (155.13 mi)
- Salto Hotels (78.32 mi)
- Federacion Hotels (55.26 mi)
- Concordia Hotels (77.86 mi)
- Gualeguaychú Hotels (184.43 mi)
- Colon Hotels (131.71 mi)
- Funes Hotels (225.28 mi)
- Zárate Hotels (261.41 mi)
Car Rentals Near Mesopotamia
- Car rentals in Rosario
- Car rentals in San Pedro
- Car rentals in Campana
- Car rentals in Termas del Arapey
- Car rentals in Posadas
- Car rentals in Encarnacion
- Car rentals in Santa Fe
- Car rentals in Carmelo
- Car rentals in Resistencia
- Car rentals in Uruguaiana
- Car rentals in Corrientes
- Car rentals in Belen de Escobar
- Car rentals in Parana
- Car rentals in Salto
- Car rentals in Federacion
- Car rentals in Concordia
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