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River City Casino & Hotel

River City Casino & Hotel

4 out of 5
777 River City Casino Blvd St. Louis MO
  • 3 hours drive from Mississippi River
Book a stay at this business-friendly hotel in St. Louis. Enjoy free parking, 5 restaurants, and a casino. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,604 reviews)
"Very nice stay no issues and price was right"

Reviewed on Jun 5, 2026

River City Casino & Hotel
Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

3 out of 5
12 Ludwig Dr Fairview Heights IL
  • 2 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,014 reviews)
"THIS PLACE IS PHENOMENAL AND THE STAFF GOES WELL BEYOND YHE CALL OF DUTY!!!"

Reviewed on Jun 5, 2026

Drury Inn & Suites St. Louis Fairview Heights
Super 8 by Wyndham O'Fallon

Super 8 by Wyndham O'Fallon

2 out of 5
1100 Eastgate Dr O'Fallon IL
  • 2 hours drive from Mississippi River
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (1,004 reviews)
"Dirty dirty dirty Dust Like they never clean super dusty and roches"

Reviewed on Jun 5, 2026

Super 8 by Wyndham O'Fallon
Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

3 out of 5
1118 Central Park Drive O'Fallon IL
  • 2 hours drive from Mississippi River
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,008 reviews)
"Great place. Our 2nd stay here. Staff are kind. Breakfast was good and the pool is cool."

Reviewed on Jun 6, 2026

Drury Inn & Suites St. Louis O'Fallon, IL
The Principal Hotel

The Principal Hotel

3.5 out of 5
310 S Main St Columbia IL
  • 3 hours drive from Mississippi River
Stay at this hotel in Columbia. Enjoy free WiFi, free parking, and a fitness center. Popular attractions Triple Lakes Golf Course and Eckert’s Millstadt Farm ...
9.6/10 Exceptional! (281 reviews)
"The property was nice. We were in town for a wedding and it was close to the venue. I booked a room that was supposed to have two queen beds and a twin size bed. It ended up having two queen beds and a very uncomfortable pullout sofa. Also, most hotels have an 11 AM checkout. This one is 10 AM and ..."

Reviewed on Jun 5, 2026

The Principal Hotel
Welcome Suites

Welcome Suites

2 out of 5
148 Regency Park O'Fallon IL
  • 2 hours drive from Mississippi River
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free WiFi, free parking, and a fitness center. Popular attractions O'Fallon Family Sports Park ...
5.8/10 (270 reviews)
"There was fighting in the halls and loud neighbors. My fridge didn't work all my food spoiled. They couldn't give me a remote that worked with the TV had to buy my own and program it. They kicked me out because I had my emotional support cats with me. Mind you I was suppose to be there 19 days and ..."

Reviewed on Jun 3, 2026

Welcome Suites
Quality Inn & Suites near St. Louis and I-255

Quality Inn & Suites near St. Louis and I-255

2.5 out of 5
1607 Pontiac Dr East St. Louis IL
  • 3 hours drive from Mississippi River
Book a stay at this business-friendly hotel in East St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
7.4/10 Good! (1,002 reviews)
"The rooms we’re half cleaned the beds we’re dirty i noticed after turning the sheets Down to go to sleep there was dirt and debris the pool water was salty don’t ask and breakfast was cold no tongs to pick up food it wasn’t flavorful the batter for waffles was sour tasting no milk that I seen I did ..."

Reviewed on May 24, 2026

Quality Inn & Suites near St. Louis and I-255
Quality Inn O'Fallon IL - St. Louis

Quality Inn O'Fallon IL - St. Louis

3 out of 5
1409 W US 50 O'Fallon IL
  • 2 hours drive from Mississippi River
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.4/10 Good! (1,003 reviews)
"It would’ve been nice if the pool water was a little bit warmer"

Reviewed on May 26, 2026

Quality Inn O'Fallon IL - St. Louis
Comfort Suites Fairview Heights - St. Louis

Comfort Suites Fairview Heights - St. Louis

2.5 out of 5
137 Ludwig Dr Fairview Heights IL
  • 2 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
6.4/10 (1,001 reviews)
"No bar so that's a lie need to be taken off website false advertising. Pool was super dirty for days with hair, trash , towels ,and eyebrows everywhere."

Reviewed on Jun 3, 2026

Comfort Suites Fairview Heights - St. Louis
Radisson Hotel Fairview Heights - St. Louis

Radisson Hotel Fairview Heights - St. Louis

3 out of 5
319 Fountains Pkwy Fairview Heights IL
  • 2 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Fairview Heights. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the helpful staff ...
7.6/10 Good! (631 reviews)
"Our stay was even better than expected. Clean rooms and property, free water bottles available in the lobby. We had our dog and there was plenty of grassy area to walk them. Restaurant onsite."

Reviewed on Jun 5, 2026

Radisson Hotel Fairview Heights - St. Louis
Red Lion Inn & Suites Caseyville

Red Lion Inn & Suites Caseyville

2 out of 5
8950 Tucker Dr Caseyville IL
  • 2 hours drive from Mississippi River
Stay at this motel in Caseyville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Pleasant Ridge Park and Cahokia Mounds State Historic ...
5.2/10 (283 reviews)
"WiFi was spotty, 15 minute no refund policy, lights didn’t work, door would not shut"

Reviewed on May 21, 2026

Red Lion Inn & Suites Caseyville
Best Western Plus MidAmerica Hotel

Best Western Plus MidAmerica Hotel

2.5 out of 5
9730 Hayden Drive Mascoutah IL
  • 2 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Mascoutah. Enjoy free breakfast, free parking, and a free airport shuttle. Our guests praise the helpful staff ...
9/10 Wonderful! (1,003 reviews)
"Super close to mid America airport. Great breakfast and they had complimentary chili in the evening."

Reviewed on Jun 6, 2026

Best Western Plus MidAmerica Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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