Search for Cheap Deals on
Hotels in Panama City

Choose from 15424 Panama City Hotel Deals

Comfort Inn & Suites

Comfort Inn & Suites

2.5 out of 5
3602 West Hwy 98 Panama City FL
  • 16 min drive from Tyndall Air Force Base Visitor Center
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,001 reviews)
"Muy agusto sin ruidos"

Reviewed on May 20, 2026

Comfort Inn & Suites
La Quinta Inn & Suites by Wyndham Panama City

La Quinta Inn & Suites by Wyndham Panama City

3 out of 5
1030 E 23rd St Panama City FL
  • 17 min drive from Tyndall Air Force Base Visitor Center
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,002 reviews)
"Clean rooms. Hotel has a fresh smell. Pool needs more umbrellas at the table or pool area. Breakfast is ok but very limited. Bed sleeps very well."

Reviewed on May 19, 2026

La Quinta Inn & Suites by Wyndham Panama City
Red Roof Inn Panama City

Red Roof Inn Panama City

2 out of 5
217 North US Hwy 231 Panama City FL
  • 15 min drive from Tyndall Air Force Base Visitor Center
Stay at this hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (1,000 reviews)
"The room was clean overall; however, the stay was uncomfortable due to several issues. The bed sheets were rough, and the bed cover was thin and uncomfortable. The room was extremely humid to the point that the floors became wet. Additionally, the bathtub was clogged, and the shower had very low ..."

Reviewed on May 18, 2026

Red Roof Inn Panama City
Comfort Inn & Suites Panama City North

Comfort Inn & Suites Panama City North

2.5 out of 5
2317 Jenks Ave Panama City FL
  • 17 min drive from Tyndall Air Force Base Visitor Center
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions St. Andrews State Park and ...
8.2/10 Very Good! (805 reviews)
"Quede muy satisfecha con todo limpieza 100%mi habitación no olia a cigarro tampoco a humedad muy trankilo muy limpio"

Reviewed on May 20, 2026

Comfort Inn & Suites Panama City North
Hilton Garden Inn Panama City Airport

Hilton Garden Inn Panama City Airport

3 out of 5
5625 Venture Crossings Blvd Panama City FL
  • 43 min drive from Tyndall Air Force Base Visitor Center
Book a stay at this business-friendly hotel in Panama City. Enjoy free parking, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff ...
9.4/10 Exceptional! (753 reviews)
"Breakfast was wonderful, but missed the avocado toast available last year"

Reviewed on May 19, 2026

Hilton Garden Inn Panama City Airport
Quality Inn Panama City North

Quality Inn Panama City North

2.5 out of 5
1013 E 23rd St Panama City FL
  • 17 min drive from Tyndall Air Force Base Visitor Center
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.6/10 Good! (736 reviews)
"Parking was easy, room was clean, staff was very helpful, and the breakfast was lovely"

Reviewed on May 18, 2026

Quality Inn Panama City North
Holiday Inn Panama City by IHG

Holiday Inn Panama City by IHG

3 out of 5
2001 Martin Luther King Boulevard Panama City FL
  • 16 min drive from Tyndall Air Force Base Visitor Center
Book a stay at this family-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.6/10 Excellent! (796 reviews)
"All was Excellent the only down fall having to pay for Breakfast, will return in October for the October Rally."

Reviewed on May 4, 2026

Holiday Inn Panama City by IHG
Best Western Plus Panama City Hotel

Best Western Plus Panama City Hotel

2.5 out of 5
Mercedes Avenue, 2338 Panama City FL
  • 17 min drive from Tyndall Air Force Base Visitor Center
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (942 reviews)
"This property was well maintained , staff was very nice . Very cleaned and remodeled."

Reviewed on May 10, 2026

Best Western Plus Panama City Hotel
Hotel Indigo Panama City Marina by IHG

Hotel Indigo Panama City Marina by IHG

3.5 out of 5
7 HARRISON AVENUE Panama City FL
  • 11 min drive from Tyndall Air Force Base Visitor Center
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, 2 restaurants, and a 24-hour fitness center. Our guests praise the helpful staff ...
9.6/10 Exceptional! (430 reviews)
"Nice place, rooms were clean and taken care of. The staff was very friendly and helpful. We will definitely return."

Reviewed on Apr 29, 2026

Hotel Indigo Panama City Marina by IHG
Comfort Suites

Comfort Suites

2.5 out of 5
264 N Tyndall Pkwy Panama City FL
  • 11 min drive from Tyndall Air Force Base Visitor Center
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (747 reviews)
"I requested a 1st floor room being a solo Female traveler i really appreciated that. Friendly staff"

Reviewed on May 7, 2026

Comfort Suites
Suburban Studios near Panama City Beach

Suburban Studios near Panama City Beach

2 out of 5
4432 W Highway 98 Panama City FL
  • 16 min drive from Tyndall Air Force Base Visitor Center
Stay at this hotel in Panama City. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Publix Sports Park and St. Andrews State Park ...
7.2/10 Good! (341 reviews)
"No paper towel. Not a single spoon or fork Internet’s super slow The access key keep deactivating Room was smell like mold But the bed was comfy Cleaning service was different.They came in took towels and trash out but didn’t make the bed"

Reviewed on May 19, 2026

Suburban Studios near Panama City Beach
Courtyard by Marriott Panama City

Courtyard by Marriott Panama City

3 out of 5
905 E 23rd Pl Panama City FL
  • 17 min drive from Tyndall Air Force Base Visitor Center
Book a stay at this business-friendly hotel in Panama City. Enjoy breakfast (surcharge), a 24-hour fitness center, and parking (surcharge). Popular attractions ...
9/10 Wonderful! (432 reviews)
"The staff was so amazing always taking t"

Reviewed on Apr 29, 2026

Courtyard by Marriott Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Panama City

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Panama City hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Panama City.

Choosing the right hotel in Florida has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Panama City’s 15,424 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $76. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Panama City hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Panama City. No matter your reason for visiting Panama City, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Panama City hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Panama City for as low as $76.

How many hotels are there in Panama City?

With over 15,424 hotels in Panama City, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $76.

How to find cheap car rentals in Panama City?

Finding a cheap car rental deal in Panama City is as easy as scoring cheap hotels in Panama City. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.