Hotels Near
East Florence

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Featured East Florence Hotels

Renaissance Shoals Resort & Spa

Renaissance Shoals Resort & Spa

3.5 out of 5
10 Hightower Place Florence AL
Fully refundableReserve now, pay when you stay
Book a stay at this spa resort in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (780 reviews)
Loved the decor that was related to the Muscle Shoals music history. The only things I didn’t like were the pillows, flat and I would have liked a coffee pot in the room. All staff excellent. Great dining experience in Grill 360. Good music in Swampers Bar and Grill. The pool area is beautiful.

Reviewed on May 7, 2026

Renaissance Shoals Resort & Spa
Residence Inn Florence Marriott

Residence Inn Florence Marriott

3 out of 5
1000 Sweetwater Ave Florence AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Regency Square Mall and Children's ...
9/10 Wonderful! (345 reviews)
All was good

Reviewed on May 12, 2026

Residence Inn Florence Marriott
Budget Inn & Suites

Budget Inn & Suites

2.5 out of 5
1238 Florence Boulevard Florence AL
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.4/10 Good! (157 reviews)
Was really clean nice room. The staff was friendly. For older mom n pop hotel was cozy place to stay the night. Thank you

Reviewed on May 8, 2026

Budget Inn & Suites
Days Inn by Wyndham Muscle Shoals Florence

Days Inn by Wyndham Muscle Shoals Florence

2 out of 5
2701 Woodward Ave Muscle Shoals AL
Fully refundableReserve now, pay when you stay
Stay at this hotel in Muscle Shoals. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.8/10 Excellent! (1,003 reviews)
Great place to stay! Nice & clean room

Reviewed on May 13, 2026

Days Inn by Wyndham Muscle Shoals Florence
Comfort Suites Florence Shoals Area

Comfort Suites Florence Shoals Area

2.5 out of 5
140 Matthew Paul Ct Florence AL
Fully refundable
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (811 reviews)
Had to request bedding for the pull-out sofa, which was fine, but was told there were no pillows. Room never seemed to get cool.

Reviewed on May 14, 2026

Comfort Suites Florence Shoals Area
The Stricklin Hotel

The Stricklin Hotel

3.5 out of 5
317 N Court St Florence AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Florence. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (864 reviews)
Get a room on the opposite side of the FloBama or else the music will keep you up until 1:00 am

Reviewed on May 10, 2026

The Stricklin Hotel
Clarion Inn Sheffield Muscle Shoals

Clarion Inn Sheffield Muscle Shoals

2.5 out of 5
4900 Hatch Blvd Sheffield AL
Fully refundable
Book a stay at this business-friendly hotel in Sheffield. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.2/10 Good! (1,006 reviews)
Tub Was Backed up, mold on the ceiling, beds uncomfortable, AC was weak and took quite a bit to cool down to a comfortable temperature. booked 6 nights, only stayed one night

Reviewed on May 11, 2026

Clarion Inn Sheffield Muscle Shoals
Spark by Hilton Tuscumbia Muscle Shoals

Spark by Hilton Tuscumbia Muscle Shoals

3.5 out of 5
712 Hwy 72 W Tuscumbia AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Tuscumbia. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (754 reviews)
Our room was spacious, the air conditioning kept us comfortable. The bed was descent, the drain in the bathroom was jammed shut. The lever wouldn't work to drain the sink. The breakfast was just bagels. Ok place to stay, just to lay your head.

Reviewed on May 13, 2026

Spark by Hilton Tuscumbia Muscle Shoals
Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals

Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals

2 out of 5
1852 Highway 72 E Tuscumbia AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Tuscumbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,001 reviews)
Hotel was not in the best shape pictures make it look better than it is. The staff had their kids there and stayed in the pool and took up chairs and space for guest and even had the table covered with food they was grilling and having to run back and forth if someone came to check in cause they ...

Reviewed on May 12, 2026

Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals
Baymont by Wyndham Florence/Muscle Shoals

Baymont by Wyndham Florence/Muscle Shoals

2.5 out of 5
115 Ana Drive Florence AL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property ...
7.2/10 Good! (938 reviews)
nice

Reviewed on May 14, 2026

Baymont by Wyndham Florence/Muscle Shoals
Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG

Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG

2.5 out of 5
180 Etta Gray Street Florence AL
Fully refundable
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG
Hampton Inn & Suites Florence-Downtown

Hampton Inn & Suites Florence-Downtown

2.5 out of 5
505 S Court St Florence AL
Fully refundableReserve now, pay when you stay
Stay at this hotel in Florence. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.2/10 Wonderful! (720 reviews)
Loved this hotel!

Reviewed on May 12, 2026

Hampton Inn & Suites Florence-Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in East Florence

Florence is a city that has a lot going on, but you have your sights set on East Florence. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that East Florence has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of East Florence hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Florence so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the East Florence underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the East Florence city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of East Florence cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in East Florence at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $73
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the East Florence hotel you want, book it, and never look back. Because your great escape is ahead of you.