Search for Cheap Deals on
Hotels in Santa Cruz

Choose from 270 Santa Cruz Hotel Deals

Camino Real Hotel

Camino Real Hotel

4.5 out of 5
Av. San Martín y 4to. Anillo, Equipetrol Norte, Santa Cruz
  • 3 min walk from Ventura Mall
Stay at this 4.5-star luxury hotel in Santa Cruz. Enjoy free breakfast, a full-service spa, and 2 bars/lounges. Popular attractions Ventura Mall and Santa Cruz ...
8.8/10 Excellent! (390 reviews)
"Great experience . Cannot say enough about the hotel. I will definitely return ."

Reviewed on Jul 8, 2025

Get rates
Camino Real Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 out of 5
Ave. San Martin, #455, Santa Cruz
  • 13 min walk from Ventura Mall
Stay at this 3.5-star spa hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (321 reviews)
"Always an amazing hotel"

Reviewed on Jun 21, 2025

Get rates
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

4.5 out of 5
San Martin Avenue Esq Street E - E, Santa Cruz
  • 9 min walk from Ventura Mall
Stay at this 4.5-star luxury hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Ventura Mall and Patio Design LifeStyle ...
9/10 Wonderful! (244 reviews)
"Location, surrounding, quietness, good service"

Reviewed on Jul 7, 2025

Get rates
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel

5 out of 5
4to Anillo Entre Radial 23, At Calle Las Ramblas, Santa Cruz, Santa Cruz
  • 10 min walk from Ventura Mall
Stay at this 5-star luxury hotel in Santa Cruz. Enjoy free parking, a full-service spa, and a rooftop terrace. Our guests praise the helpful staff and the property ...
9/10 Wonderful! (191 reviews)
"all"

Reviewed on Jun 5, 2025

Get rates
Marriott Santa Cruz de la Sierra Hotel
Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra

3 out of 5
AVENIDA CRISTOBAL DE MENDOZA, Santa Cruz
  • 25 min walk from Ventura Mall
Stay at this 3-star business-friendly hotel in Santa Cruz. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
9.4/10 Exceptional! (45 reviews)
"Predictable, good vibe. Very good bed."

Reviewed on Oct 22, 2024

Get rates
Ibis Santa Cruz DE LA Sierra
TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz

4 out of 5
Av. San Martin, Calle 9 Este, no. 4, Equipetrol., Santa Cruz
  • 15 min walk from Ventura Mall
Stay at this 4-star hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.2/10 Wonderful! (124 reviews)
"It should have a dinning room for meals not just breakfast"

Reviewed on Jul 5, 2025

Get rates
TRYP by Wyndham Santa Cruz
Sun Hotel

Sun Hotel

3.5 out of 5
Av. Banzer Km 13, Aeropuerto Internacional Viru Viru, Santa Cruz, Santa Cruz
  • 17 min drive from Ventura Mall
Stay at this 3.5-star business-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attraction Play Land Amusement Park is ...
8.2/10 Very Good! (303 reviews)
"Staff are friendly and helpful! Great landing spot after a long flight (it’s just 5 mins from airport)."

Reviewed on Jul 7, 2025

Get rates
Sun Hotel
Delfines Collection Hotel By Mercure

Delfines Collection Hotel By Mercure

3.5 out of 5
Calle Pablo Sanz 29 Equipetrol, Santa Cruz
  • 10 min walk from Ventura Mall
Stay at this 3.5-star hotel in Santa Cruz. Enjoy free WiFi, room service, and daily housekeeping. Popular attractions Ventura Mall and Santa Cruz Zoo are located ...
9/10 Wonderful! (59 reviews)
"La atención, la ubicación, la comodidad y la limpieza. Todo lo importante está excelente"

Reviewed on Jun 23, 2025

Get rates
Delfines Collection Hotel By Mercure
Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra

5 out of 5
AV ROCA CORONADO 901, ENTRE TERCER Y CUARTO ANILLO, Santa Cruz
  • 5 min drive from Ventura Mall
Stay at this 5-star luxury hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Parque Ecológico and Patio Design LifeStyle ...
9/10 Wonderful! (95 reviews)
"The best place , best workers"

Reviewed on Apr 20, 2025

Get rates
Novotel Santa Cruz De La Sierra
Hotel LP Santa Cruz Centro

Hotel LP Santa Cruz Centro

3 out of 5
Av.Ejercito Nacional 290, (frente Stadium Tahuichi), Santa Cruz
  • 7 min drive from Ventura Mall
Stay at this 3-star business-friendly hotel in Santa Cruz. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Ramon Tahuichi Aguilera ...
7.8/10 Good! (280 reviews)
"Clean, friendly staff"

Reviewed on Jun 2, 2024

Get rates
Hotel LP Santa Cruz Centro
Lido Hotel

Lido Hotel

3 out of 5
Calle 21 de Mayo 527, Santa Cruz
  • 4 min drive from Ventura Mall
Stay at this 3-star hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Arenal Park and Ethno-folkloric Museum are located ...
8.8/10 Excellent! (22 reviews)
"Clean, with AC and both hot and cold water."

Reviewed on Jun 26, 2025

Get rates
Lido Hotel
Hotel LP Equipetrol

Hotel LP Equipetrol

3.5 out of 5
Dr Victor Pinto, Equipetrol, esquina Marcelo Terceros Banzer, Santa Cruz
  • 11 min walk from Ventura Mall
Stay at this 3.5-star hotel in Santa Cruz. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Ventura Mall and Santa Cruz Zoo are ...
8/10 Very Good! (198 reviews)
"So, the mattress and pillows were not that comfortable, hard. No microwave and the sheets not the size of the bed, smaller. The treatment from the hotel personnel was good."

Reviewed on Feb 21, 2025

Get rates
Hotel LP Equipetrol
See all 270 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.