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Hotels in Santa Cruz


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Top Cities in Santa Cruz

Hotels in Santa Cruz

Marriott Santa Cruz de la Sierra Hotel
Marriott Santa Cruz de la Sierra Hotel
5 out of 5
4to Anillo Entre Radial 23, At Calle Las Ramblas, Santa Cruz, Santa Cruz
Stay at this 5-star luxury hotel in Santa Cruz. Enjoy free parking, a full-service spa, and a rooftop terrace. Our guests praise the helpful staff and the property ...
Marriott Santa Cruz de la Sierra Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 out of 5
Ave. San Martin, #455, Santa Cruz
Stay at this 3.5-star spa hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Camino Real Hotel
Camino Real Hotel
4.5 out of 5
Av. San Martín y 4to. Anillo, Equipetrol Norte, Santa Cruz
Stay at this 4.5-star luxury hotel in Santa Cruz. Enjoy free breakfast, a full-service spa, and 2 bars/lounges. Popular attractions Ventura Mall and Santa Cruz ...
Camino Real Hotel
Sun Hotel
Sun Hotel
3.5 out of 5
Av. Banzer Km 13, Aeropuerto Internacional Viru Viru, Santa Cruz, Santa Cruz
Stay at this 3.5-star business-friendly hotel in Santa Cruz. Enjoy free WiFi, free parking, and a free airport shuttle. Popular attraction Play Land Amusement ...
Sun Hotel
Delfines Collection Hotel By Mercure
Delfines Collection Hotel By Mercure
3.5 out of 5
Calle Pablo Sanz 29 Equipetrol, Santa Cruz
Stay at this 3.5-star hotel in Santa Cruz. Enjoy an outdoor pool. Popular attractions Ventura Mall and Santa Cruz Zoo are located nearby.
Delfines Collection Hotel By Mercure
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 out of 5
San Martin Avenue Esq Street E - E, Santa Cruz
Stay at this 4.5-star luxury hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Ventura Mall and Patio Design LifeStyle ...
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
TRYP by Wyndham Santa Cruz
TRYP by Wyndham Santa Cruz
4 out of 5
Av. San Martin, Calle 9 Este, no. 4, Equipetrol., Santa Cruz
Stay at this 4-star hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
TRYP by Wyndham Santa Cruz
Novotel Santa Cruz De La Sierra
Novotel Santa Cruz De La Sierra
5 out of 5
AV ROCA CORONADO 901, ENTRE TERCER Y CUARTO ANILLO, Santa Cruz
Stay at this 5-star luxury hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Parque Ecológico and Patio Design LifeStyle ...
Novotel Santa Cruz De La Sierra
Swissôtel Santa Cruz De La Sierra
Swissôtel Santa Cruz De La Sierra
4.5 out of 5
5to anillo Avenida La Salle # 4500, Santa Cruz
Stay at this 4.5-star luxury hotel in Santa Cruz. Enjoy free WiFi, a full-service spa, and 2 bars/lounges. Popular attractions Ventura Mall and Santa Cruz Zoo ...
Swissôtel Santa Cruz De La Sierra
Ibis Santa Cruz DE LA Sierra
Ibis Santa Cruz DE LA Sierra
3 out of 5
AVENIDA CRISTOBAL DE MENDOZA, Santa Cruz
Stay at this 3-star business-friendly hotel in Santa Cruz. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
Ibis Santa Cruz DE LA Sierra
Hotel G
Hotel G
3.5 out of 5
Av. Pedro Ribera #750, Santa Cruz, Santa Cruz
Stay at this 3.5-star hotel in Santa Cruz. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Las Brisas Shopping Center and Santa ...
Hotel G
Hotel LP Equipetrol
Hotel LP Equipetrol
3.5 out of 5
Dr Victor Pinto, Equipetrol, esquina Marcelo Terceros Banzer, Santa Cruz
Stay at this 3.5-star hotel in Santa Cruz. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Ventura Mall and Santa Cruz Zoo are ...
Hotel LP Equipetrol
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Santa Cruz 

2025 is the year you’ve decided to satisfy that travel urge. This trip you plan to mix it up a bit. You want a great place to stay, but also plan to hit up the places most tourists don’t even know about. So, can you get a great hotel in Santa Cruz for a steal? No doubt, and you’ll have cash left over to do this trip up the way you want.

This must be the place

Just how you like to live life a little differently, we do hotel bookings against the grain. You won’t have to decide between staying at one of the best hotels in Santa Cruz or scoring reservations at one of the hippest restaurants in Santa Cruz. With Hotwire, you can have both, and then some. After booking your place, you’ll have extra cash to tack on last-minute concert tickets, check out those off-beat sites, and do a little souvenir shopping because you’re all about setting your social feeds on fire, without burning your bank account.

Let us help you deal

You’re someone that likes to game the system, so choose the Hotwire Hot Rate. You’ll get the Santa Cruz hotel you’ve been eyeing at a price that’ll make you check twice to see if it’s real. Yes, the price is right. We have several ways for you to pick your preferred pad, and no matter which way you go, you’ll snag a hotel that you’ll brag about. Filter by:

  • Hotwire Hot Rate: You get some of the best hotels in Santa Cruz at ridiculously cheap rates—you’ll find out the hotel name after you book. You might even score a 4-star hotel at a 2-star price.

  • Price: Have a tight budget this go around? No worries. We have hotels for all price ranges, with rooms starting at $37.

  • Amenities: Heated pool? Maybe a private balcony with a view? Find the hotel that your dreams are made of.

Make your best year yet, and snap up one of the 250 killer Santa Cruz hotel deals and be the person that travel bloggers come to for advice.