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Santee National Wildlife Refuge Vacation Packages

Santee National Wildlife Refuge Last Minute Hotel Deals

Baymont by Wyndham Santee

249 Britain Street, Santee, SC

Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Tru By Hilton Santee

263 Britain St. and 273 Britain St., Santee, SC

Stay at this hotel in Santee. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...

Fairfield Inn & Suites by Marriott Santee

9074 Old Number Six Hwy, Santee, SC

Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...

Hampton Inn Santee-I-95

9060 Old Number Six Hwy, Santee, SC

Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...

Comfort Inn & Suites Santee

221 Britain St, Santee, SC

Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...

Quality Inn & Suites

8929 Old Number Six Highway, Santee, SC

Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...

Travelodge by Wyndham Santee

9117 Old Number Six Hwy, Santee, SC

Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...

Holiday Inn Santee, an IHG Hotel

139 Bradford Blvd, Santee, SC

Stay at this 3-star golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...

See all 322 properties in Santee National Wildlife Refuge

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.