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Independent in St. Charles

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Featured St. Charles Independent

Clayton Plaza Hotel & Extended Stay
Clayton Plaza Hotel & Extended Stay
3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
Clayton Plaza Hotel & Extended Stay
Moonrise Hotel
Moonrise Hotel
4 out of 5
6177 Delmar Blvd, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4-star boutique hotel in St. Louis. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the restaurant and the bar in our reviews. ...
Moonrise Hotel
Forest Park Hotel by MDR
Forest Park Hotel by MDR
3 out of 5
5915 Wilson Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the ...
Forest Park Hotel by MDR
The Last Hotel
The Last Hotel
4.5 out of 5
1501 Washington Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, a 24-hour fitness center, and valet parking (surcharge). Our guests praise the pool and the ...
The Last Hotel
Casino Queen Hotel
Casino Queen Hotel
3 out of 5
200 Front Street, East St. Louis, IL
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in East St. Louis. Enjoy free WiFi, free parking, and a casino. Our guests praise the helpful staff and the clean ...
Casino Queen Hotel
The Cheshire
The Cheshire
4 out of 5
6300 Clayton Rd, Richmond Heights, MO
Fully refundableReserve now, pay when you stay
Stay at this 4-star boutique hotel in Richmond Heights. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
The Cheshire
The Wildwood Hotel
The Wildwood Hotel
3.5 out of 5
2801 Fountain Pl, Wildwood, MO
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Wildwood. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the convenient ...
The Wildwood Hotel
Angad Arts Hotel
Angad Arts Hotel
4 out of 5
3550 Samuel Shepard Drive, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...
Angad Arts Hotel
Relax Inn Saint Charles
Relax Inn Saint Charles
2 out of 5
3800 Harry S Truman Blvd, St. Charles, MO
Fully refundable
Stay at this motel in St. Charles. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the clean rooms in our reviews. Popular attractions ...
Relax Inn Saint Charles
The Charles F. Knight Center
The Charles F. Knight Center
2.5 out of 5
Throop Drive and Snow Way, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
The Charles F. Knight Center
The West End
The West End
2 out of 5
4215 Lindell Blvd, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this hotel in St. Louis. Enjoy free WiFi, parking (surcharge), and laundry facilities. Popular attractions St. Louis Union Station and Forest Park are ...
The West End
Missouri Athletic Club
Missouri Athletic Club
3.5 out of 5
405 Washington Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
Missouri Athletic Club
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Independent hotels in St. Charles

You’ve already taken the guesswork out of your next vacation. You know you want a Independent hotel in St. Charles. What can you say? You like their style, they’re in a good part of St. Charles, and they never let you down. New bar in town? You’re the first one to check it out. Spiciest item on the menu? You can take the heat. But even the best gamblers hedge their bets. No matter how crazy good your trip is, you want something familiar waiting for you at the end of the day.

All in a name

We all have favorites. There’s nothing wrong with knowing what you like. You like to stay at Independent near , St. Charles to do the tourist thing (because sometimes it is fun) and then hit up the places that aren’t on the map. And no matter what fun you get into, you have Independent hotels with their comfy beds and thoughtful amenities waiting to tuck you in.

As you like it

Have a price you want to stick to, so you can paint the town red? Maybe, it’s all about the hotel features. Who couldn’t use a hot tub? Pick your pleasure by:

  • Hotwire Hot Rate: Grab the Independent hotel in St. Charles at an absolute steal. After you book it, we’ll tell you the hotel name. You might nab that 4-star hotel for a 2-star price.
  • Price: How low can we go? Quite low in fact. Check out our prices per night, starting at $68.
  • Amenities: Grab a cocktail at the lounge and maybe wander upstairs to the rooftop terrace—all the stuff that makes a great vacay.

You’ve already done the hard part—figuring out where you want to stay. Now it’s time to use the money you saved to let the real fun begin. Underground shows? Off-beat attractions? Rooftop escapes? The choice is yours. The only thing wonderfully predictable about this trip is the Independent room you’ll be staying in.