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Hotels in Wesco

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Days Inn by Wyndham Rolla

Days Inn by Wyndham Rolla

2.5 out of 5
2006 N Bishop Ave Rolla MO
  • 2 hours drive from Mark Twain National Forest
Book a stay at this business-friendly hotel in Rolla. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (1,003 reviews)
"No working ice machine, very difficult to find front door of this hotel and whole place in desperate need of renovation. Laminated floors so can hear every step in rooms above. Found wad of hair on bed. Got this room with expedia so very glad didn't pay the walk in rate."

Reviewed on Nov 8, 2026

Days Inn by Wyndham Rolla
Greenlight Inn & Suites

Greenlight Inn & Suites

2 out of 5
110 N Outer Rd St. James MO
  • 2 hours drive from Mark Twain National Forest
Book a stay at this business-friendly hotel in St. James. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (636 reviews)
"I would not cons"

Reviewed on Nov 10, 2026

Greenlight Inn & Suites
Days Inn & Suites by Wyndham Cuba

Days Inn & Suites by Wyndham Cuba

2 out of 5
97 Ozark Drive Cuba MO
  • 2 hours drive from Mark Twain National Forest
Book a stay at this business-friendly hotel in Cuba. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
7.4/10 Good! (871 reviews)
"Great stay. Pretty clean and friendly"

Reviewed on Nov 8, 2026

Days Inn & Suites by Wyndham Cuba
Economy Inn

Economy Inn

2.5 out of 5
102 N Outer Rd St. James MO
  • 2 hours drive from Mark Twain National Forest
Stay at this motel in St. James. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (531 reviews)
"Very quiet and peaceful area!!! I got plenty of rest!!! The staff was very knowledgeable, very helpul and attentive. I will definitely stay here again!!! Thank you Chet!!!"

Reviewed on Nov 7, 2026

Economy Inn
Hampton Inn Rolla

Hampton Inn Rolla

2.5 out of 5
2201 N Bishop Ave Rolla MO
  • 2 hours drive from Mark Twain National Forest
Book a stay at this business-friendly hotel in Rolla. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Hampton Inn Rolla
Super 8 by Wyndham Cuba

Super 8 by Wyndham Cuba

2 out of 5
28 Highway P Cuba MO
  • 2 hours drive from Mark Twain National Forest
Book a stay at this business-friendly motel in Cuba. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.8/10 Excellent! (1,005 reviews)
"The room was clean and in good condition. It had a mini-fridge, microwave, tv, comfortable pillows and clean towels. I'd stay there again."

Reviewed on Nov 9, 2026

Super 8 by Wyndham Cuba
Motel 6 Rolla, MO

Motel 6 Rolla, MO

2 out of 5
2001 N Bishop Ave Rolla MO
  • 2 hours drive from Mark Twain National Forest
Stay at this motel in Rolla. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
6.6/10 (293 reviews)
"I stayed there last night. The room was clean, the property was clean. My only issue was that I was asked to wait 15 minutes prior to entering tje room so they could make sure it was clean. I checked in late, after 10 pm so I think they should've known if the room was clean. I slept really good and ..."

Reviewed on Nov 6, 2026

Motel 6 Rolla, MO
Finn's 66 Motel

Finn's 66 Motel

2.5 out of 5
777 Grover St St. James MO
  • 2 hours drive from Mark Twain National Forest
Stay at this motel in St. James. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7.8/10 Good! (347 reviews)
"Great time. Will stay again"

Reviewed on Oct 4, 2026

Finn's 66 Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Wesco

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Wesco.

Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Wesco’s 160 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $57. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Wesco hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Wesco. No matter your reason for visiting Wesco, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Wesco hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Wesco for as low as $57.

How many hotels are there in Wesco?

With over 160 hotels in Wesco, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $57.

How to find cheap car rentals in Wesco?

Finding a cheap car rental deal in Wesco is as easy as scoring cheap hotels in Wesco. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.