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4 Star Hotels in Antigua Guatemala

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Featured 4 Star Antigua Guatemala Hotels

Hotel Museo Spa Casa Santo Domingo
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 1 min walk from Casa Santo Domingo Museum
The price is $298 per night from Jan 6 to Jan 7
$298
includes taxes & fees
Jan 6 - Jan 7, 2025
Stay at this 4.5-star luxury hotel in Antigua Guatemala. Enjoy free parking, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the ...
Hotel Museo Spa Casa Santo Domingo
Hotel Camino Real Antigua
4 out of 5
Fully refundableReserve now, pay when you stay
  • 8 min walk from Casa Santo Domingo Museum
The price is $263 per night from Jan 5 to Jan 6
$263
includes taxes & fees
Jan 5 - Jan 6, 2025
Stay at this 4-star spa hotel in Antigua Guatemala. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property ...
Hotel Camino Real Antigua
Hotel Soleil La Antigua
4 out of 5
Fully refundableReserve now, pay when you stay
  • 12 min walk from Casa Santo Domingo Museum
The price is $145 per night from Dec 26 to Dec 27
$145
includes taxes & fees
Dec 26 - Dec 27
Stay at this 4-star spa hotel in Antigua Guatemala. Enjoy free parking, 3 outdoor pools, and a full-service spa. Our guests praise the helpful staff and the ...
Hotel Soleil La Antigua
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Good Hotel Antigua
4 out of 5
Fully refundable
  • 5 min walk from Casa Santo Domingo Museum
The price is $185 per night from Jan 2 to Jan 3
$185
includes taxes & fees
Jan 2 - Jan 3, 2025
Stay at this 4-star hotel in Antigua Guatemala. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the property ...
Good Hotel Antigua
Hotel Boutique Los Pasos & Spa
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 9 min walk from Casa Santo Domingo Museum
The price is $250 per night from Jan 20 to Jan 21
$250
includes taxes & fees
Jan 20 - Jan 21, 2025
Stay at this 4.5-star luxury hotel in Antigua Guatemala. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property ...
Hotel Boutique Los Pasos & Spa
Porta Hotel Antigua
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 8 min walk from Casa Santo Domingo Museum
The price is $211 per night from Jan 6 to Jan 7
$211
includes taxes & fees
Jan 6 - Jan 7, 2025
Stay at this 4.5-star luxury hotel in Antigua Guatemala. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the clean ...
Porta Hotel Antigua
Hotel Casa Rustica
4 out of 5
  • 5 min walk from Casa Santo Domingo Museum
The price is $50 per night from Jan 2 to Jan 3
$50
includes taxes & fees
Jan 2 - Jan 3, 2025
Stay at this 4-star family-friendly hotel in Antigua Guatemala. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful ...
Hotel Casa Rustica
Mestizo Antigua
4 out of 5
  • 5 min walk from Casa Santo Domingo Museum
The price is $159 per night from Jan 2 to Jan 3
$159
includes taxes & fees
Jan 2 - Jan 3, 2025
Stay at this 4-star spa hotel in Antigua Guatemala. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
Mestizo Antigua
Hotel La Catedral
4 out of 5
Fully refundableReserve now, pay when you stay
  • 5 min walk from Casa Santo Domingo Museum
The price is $186 per night from Jan 8 to Jan 9
$186
includes taxes & fees
Jan 8 - Jan 9, 2025
Stay at this 4-star business-friendly hotel in Antigua Guatemala. Enjoy free breakfast, free WiFi, and room service. Our guests praise the helpful staff in our ...
Hotel La Catedral
Las Cruces Boutique Hotel
4 out of 5
Fully refundableReserve now, pay when you stay
  • 3 min walk from Casa Santo Domingo Museum
The price is $290 per night from Jan 6 to Jan 7
$290
includes taxes & fees
Jan 6 - Jan 7, 2025
Stay at this 4-star business-friendly hotel in Antigua Guatemala. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
Las Cruces Boutique Hotel
Pensativo House Hotel
4.5 out of 5
  • 10 min walk from Casa Santo Domingo Museum
The price is $214 per night from Jan 7 to Jan 8
$214
includes taxes & fees
Jan 7 - Jan 8, 2025
Stay at this 4.5-star luxury hotel in Antigua Guatemala. Enjoy free WiFi, free parking, and a rooftop terrace. Our guests praise the helpful staff and the room ...
Pensativo House Hotel
Casa Encantada by Porta Hotels
4 out of 5
Fully refundableReserve now, pay when you stay
  • 10 min walk from Casa Santo Domingo Museum
The price is $134 per night from Jan 5 to Jan 6
$134
includes taxes & fees
Jan 5 - Jan 6, 2025
Stay at this 4-star family-friendly B&B in Antigua Guatemala. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in ...
Casa Encantada by Porta Hotels
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4-star hotels in Antigua Guatemala

When you want to live it up, but not bust your bank account, then there’s nothing better than a 4-star hotel in Antigua Guatemala for your next trip. You’ll get all the amenities you can think of (and then some) at a rate within your means.

No fault in our stars

So what’s with the star rating anyway? Good question. The star rating has little to do with the price, and more to do with the amenities. 4-Star hotels in Antigua Guatemala as well as everywhere else, usually have all those thoughtful touches that make you go “Ooh,” “Ahh,” and ”YES!” Think amenities like luxury bedding, high-end electronics, concierge service, and restaurants that make eating in a gourmet experience.

Stars that shine

You know there are as many underground spots, inviting lounges, memory-making music venues as there are stars in the sky. But you’ll need the funds to check them all off. That’s why we give you the chance to take us up on the Hotwire Hot Rate. You can snag Antigua Guatemala 4-star hotels and still have plenty of leftover cash to paint the town whatever color you want. Filter hotels by:

  • Hotwire Hot Rate: We’ll snag you a crazy deal on a room by finding your hotel name after you book.
  • Price: You know that paying full price is for suckers? You can get a cheap 4-star hotel in Antigua Guatemala starting at $50 per night.
  • Amenities: What makes you flip for your trip? Full-service spa? Heated pool? 24-hour room service? Get a hotel that’ll send you over the moon.

Do you deserve a swanky hotel with a ton of amenities? Yes, yes you do. And you also deserve a sweet deal on it. Book with Hotwire today and get that star-studded Antigua Guatemala 4-star hotel and have plenty of cash left over to spend at that secret super star joint in the city.