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4 Star Hotels in Frederick

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Featured 4 Star Frederick Hotels

Lansdowne Resort and Spa
4 out of 5
Fully refundableReserve now, pay when you stay
  • 59 min drive from Fort Detrick
The price is $253 per night from Mar 23 to Mar 24
$253
includes taxes & fees
Mar 23 - Mar 24
Stay at this 4-star golf resort in Leesburg. Enjoy an outdoor pool, a golf course, and breakfast (surcharge). Our guests praise the helpful staff and the property ...
Lansdowne Resort and Spa
DoubleTree by Hilton Columbia
4 out of 5
Fully refundableReserve now, pay when you stay
  • 34 min drive from Fort Detrick
The price is $117 per night from Apr 13 to Apr 14
$117
includes taxes & fees
Apr 13 - Apr 14
Stay at this 4-star business-friendly hotel in Columbia. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
DoubleTree by Hilton Columbia
Canopy by Hilton Washington DC Bethesda North
4 out of 5
Fully refundable
  • 1 hour drive from Fort Detrick
The price is $122 per night from Apr 18 to Apr 19
$122
includes taxes & fees
Apr 18 - Apr 19
Stay at this 4-star spa hotel in Rockville. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
Canopy by Hilton Washington DC Bethesda North
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Hotel Gettysburg
4 out of 5
  • 1 hour drive from Fort Detrick
The price is $120 per night from Mar 31 to Apr 1
$120
includes taxes & fees
Mar 31 - Apr 1
Book a stay at this business-friendly hotel in Gettysburg. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the restaurant ...
Hotel Gettysburg
WhyHotel by Placemakr Columbia
4 out of 5
Fully refundableReserve now, pay when you stay
  • 37 min drive from Fort Detrick
The price is $131 per night from Apr 6 to Apr 7
$131
includes taxes & fees
Apr 6 - Apr 7
Stay at this 4-star aparthotel in Columbia. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff and the clean rooms ...
WhyHotel by Placemakr Columbia
Hilton Washington DC/Rockville Hotel & Executive Meeting Ctr
4 out of 5
Fully refundableReserve now, pay when you stay
  • 1 hour drive from Fort Detrick
The price is $146 per night from Mar 21 to Mar 22
$146
includes taxes & fees
Mar 21 - Mar 22
Book a stay at this family-friendly hotel in Rockville. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
Hilton Washington DC/Rockville Hotel & Executive Meeting Ctr
DoubleTree by Hilton Washington DC North/Gaithersburg
4 out of 5
Fully refundableReserve now, pay when you stay
  • 48 min drive from Fort Detrick
The price is $126 per night from Mar 28 to Mar 29
$126
includes taxes & fees
Mar 28 - Mar 29
Stay at this 4-star business-friendly hotel in Gaithersburg. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
DoubleTree by Hilton Washington DC North/Gaithersburg
Marriott Owings Mills Metro Centre
4 out of 5
Fully refundableReserve now, pay when you stay
  • 17 min drive from Fort Detrick
The price is $156 per night from Apr 6 to Apr 7
$156
includes taxes & fees
Apr 6 - Apr 7
Stay at this 4-star business-friendly hotel in Owings Mills. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
Marriott Owings Mills Metro Centre
Merriweather Lakehouse, Autograph Collection
4 out of 5
Fully refundableReserve now, pay when you stay
  • 35 min drive from Fort Detrick
The price is $249 per night from Apr 4 to Apr 5
$249
includes taxes & fees
Apr 4 - Apr 5
Stay at this 4-star business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. ...
Merriweather Lakehouse, Autograph Collection
DoubleTree by Hilton Baltimore North - Pikesville
4 out of 5
Fully refundableReserve now, pay when you stay
  • 18 min drive from Fort Detrick
The price is $136 per night from Mar 24 to Mar 25
$136
includes taxes & fees
Mar 24 - Mar 25
Stay at this 4-star business-friendly hotel in Pikesville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
DoubleTree by Hilton Baltimore North - Pikesville
Bethesda North Marriott Hotel & Conference Center
4 out of 5
  • 1 hour drive from Fort Detrick
The price is $191 per night from Apr 4 to Apr 5
$191
includes taxes & fees
Apr 4 - Apr 5
Stay at this 4-star golf hotel in Rockville. Enjoy breakfast (surcharge), 24-hour room service, and a 24-hour fitness center. Our guests praise the helpful staff ...
Bethesda North Marriott Hotel & Conference Center
DoubleTree by Hilton Sterling - Dulles Airport
4 out of 5
Fully refundableReserve now, pay when you stay
  • 1 hour drive from Fort Detrick
The price is $132 per night from Mar 30 to Mar 31
$132
includes taxes & fees
Mar 30 - Mar 31
Stay at this 4-star hotel in Sterling. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular ...
DoubleTree by Hilton Sterling - Dulles Airport
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4-Star Hotels in Frederick

You want it all, but you'd rather not spend all of your savings. The perfect answer? Booking a swanky 4-star hotel in Frederick for your next once-in-a-lifetime trip. Every amenity on your wish list? You've got it. From welcoming staff indulging your every whim to luxury bedding and exquisite dining, you get it all without breaking the bank. Make your next big vacation one for the books and one that will make your friends back home green with envy when you book a Frederick 4-star hotel.

No fault in our stars

So what's the deal with the star rating anyway? Here's the deal: The rating has little to do with the price of the room, and a lot more to do with the glowing amenities. 4-star hotels in Frederick, Maryland, or anywhere else, frequently have many high-end touches that make you go "Ahh," "Wow," and "YES!" Think amenities like sophisticated gadgets, luxury bed linens, concierge services, and bistros that make eating in a meal for the books.

Written in the stars

Yeah, there are as many underground spots, inviting lounges, and memory-making music venues as there are stars in the sky. But you gotta have the funds to check them all off. That's why Hotwire gives you the chance to enjoy some modest savings with the Hotwire Hot Rate. You can grab Frederick 4-star hotels and still have plenty of spending money to paint the town red. We have so many awesome choices for your stay that we've decided to make it a little easier to select the right hotel. Filter the best 4-star hotels in Frederick by:

  • Hotwire Hot Rate: In search of the best deals around? Let us pick your hotel. We'll tell you exactly where you're staying after you book, and your accommodations and savings will be spectacular.
  • Price: With rooms as cheap as $117, we know you'll find a cheap 4-star hotel in Frederick within your budget.
  • Amenities: Looking for all the bells and whistles? Perhaps a full spa, a rooftop bar, maybe even concierge service? Get the perfect amenities for you.

Do you really want a fancy hotel loaded with extras? Of course you do. And you also deserve a sweet price on it. Book with us today and get that star-studded Frederick 4-star hotel and have enough cash in your pocket to spend at that secret superstar joint in the city. If you're looking to stay in one of the most popular rooms in our 1,691 Frederick hotels, book today because our top-selling rooms could be gone in a flash.