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4 Star Hotels in Frederick

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Featured 4 Star Frederick Hotels

DoubleTree by Hilton Washington DC North/Gaithersburg
4 out of 5
Fully refundableReserve now, pay when you stay
  • 48 min drive from Fort Detrick
The price is $116 per night from Feb 1 to Feb 2
$116
includes taxes & fees
Feb 1 - Feb 2
Stay at this 4-star business-friendly hotel in Gaithersburg. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
DoubleTree by Hilton Washington DC North/Gaithersburg
DoubleTree by Hilton Columbia
4 out of 5
Fully refundableReserve now, pay when you stay
  • 34 min drive from Fort Detrick
The price is $105 per night from Feb 2 to Feb 3
$105
includes taxes & fees
Feb 2 - Feb 3
Stay at this 4-star business-friendly hotel in Columbia. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
DoubleTree by Hilton Columbia
Hilton Washington DC/Rockville Hotel & Executive Meeting Ctr
4 out of 5
Fully refundableReserve now, pay when you stay
  • 1 hour drive from Fort Detrick
The price is $126 per night from Jan 31 to Feb 1
$126
includes taxes & fees
Jan 31 - Feb 1
Book a stay at this family-friendly hotel in Rockville. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
Hilton Washington DC/Rockville Hotel & Executive Meeting Ctr
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WhyHotel by Placemakr Columbia
4 out of 5
Fully refundableReserve now, pay when you stay
  • 37 min drive from Fort Detrick
The price is $131 per night from Feb 9 to Feb 10
$131
includes taxes & fees
Feb 9 - Feb 10
Stay at this 4-star aparthotel in Columbia. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff and the clean rooms ...
WhyHotel by Placemakr Columbia
Hotel Gettysburg
4 out of 5
Fully refundableReserve now, pay when you stay
  • 1 hour drive from Fort Detrick
The price is $141 per night from Feb 5 to Feb 6
$141
includes taxes & fees
Feb 5 - Feb 6
Book a stay at this business-friendly hotel in Gettysburg. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the restaurant ...
Hotel Gettysburg
Canopy by Hilton Washington DC Bethesda North
4 out of 5
Fully refundableReserve now, pay when you stay
  • 1 hour drive from Fort Detrick
The price is $158 per night from Jan 25 to Jan 26
$158
includes taxes & fees
Jan 25 - Jan 26
Stay at this 4-star spa hotel in Rockville. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
Canopy by Hilton Washington DC Bethesda North
Lansdowne Resort and Spa
4 out of 5
Fully refundableReserve now, pay when you stay
  • 59 min drive from Fort Detrick
The price is $253 per night from Jan 26 to Jan 27
$253
includes taxes & fees
Jan 26 - Jan 27
Stay at this 4-star golf resort in Leesburg. Enjoy an outdoor pool, a golf course, and breakfast (surcharge). Our guests praise the helpful staff and the property ...
Lansdowne Resort and Spa
Marriott Owings Mills Metro Centre
4 out of 5
Fully refundableReserve now, pay when you stay
  • 17 min drive from Fort Detrick
The price is $166 per night from Feb 9 to Feb 10
$166
includes taxes & fees
Feb 9 - Feb 10
Stay at this 4-star business-friendly hotel in Owings Mills. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
Marriott Owings Mills Metro Centre
Bethesda North Marriott Hotel & Conference Center
4 out of 5
Fully refundableReserve now, pay when you stay
  • 1 hour drive from Fort Detrick
The price is $153 per night from Feb 7 to Feb 8
$153
includes taxes & fees
Feb 7 - Feb 8
Stay at this 4-star golf hotel in Rockville. Enjoy breakfast (surcharge), 24-hour room service, and a 24-hour fitness center. Our guests praise the helpful staff ...
Bethesda North Marriott Hotel & Conference Center
DoubleTree by Hilton Baltimore North - Pikesville
4 out of 5
Fully refundableReserve now, pay when you stay
  • 18 min drive from Fort Detrick
The price is $136 per night from Jan 29 to Jan 30
$136
includes taxes & fees
Jan 29 - Jan 30
Stay at this 4-star business-friendly hotel in Pikesville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
DoubleTree by Hilton Baltimore North - Pikesville
Merriweather Lakehouse, Autograph Collection
4 out of 5
Fully refundableReserve now, pay when you stay
  • 35 min drive from Fort Detrick
The price is $249 per night from Jan 30 to Jan 31
$249
includes taxes & fees
Jan 30 - Jan 31
Stay at this 4-star business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. ...
Merriweather Lakehouse, Autograph Collection
DoubleTree by Hilton Sterling - Dulles Airport
4 out of 5
Fully refundableReserve now, pay when you stay
  • 1 hour drive from Fort Detrick
The price is $115 per night from Feb 1 to Feb 2
$115
includes taxes & fees
Feb 1 - Feb 2
Stay at this 4-star hotel in Sterling. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular ...
DoubleTree by Hilton Sterling - Dulles Airport
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4-Star Hotels in Frederick

You want it all, but you'd rather not spend all of your savings. The perfect answer? Booking a swanky 4-star hotel in Frederick for your next once-in-a-lifetime trip. Every amenity on your wish list? You've got it. From welcoming staff indulging your every whim to luxury bedding and exquisite dining, you get it all without breaking the bank. Make your next big vacation one for the books and one that will make your friends back home green with envy when you book a Frederick 4-star hotel.

No fault in our stars

So what's the deal with the star rating anyway? Here's the deal: The rating has little to do with the price of the room, and a lot more to do with the glowing amenities. 4-star hotels in Frederick, Maryland, or anywhere else, frequently have many high-end touches that make you go "Ahh," "Wow," and "YES!" Think amenities like sophisticated gadgets, luxury bed linens, concierge services, and bistros that make eating in a meal for the books.

Written in the stars

Yeah, there are as many underground spots, inviting lounges, and memory-making music venues as there are stars in the sky. But you gotta have the funds to check them all off. That's why Hotwire gives you the chance to enjoy some modest savings with the Hotwire Hot Rate. You can grab Frederick 4-star hotels and still have plenty of spending money to paint the town red. We have so many awesome choices for your stay that we've decided to make it a little easier to select the right hotel. Filter the best 4-star hotels in Frederick by:

  • Hotwire Hot Rate: In search of the best deals around? Let us pick your hotel. We'll tell you exactly where you're staying after you book, and your accommodations and savings will be spectacular.
  • Price: With rooms as cheap as $105, we know you'll find a cheap 4-star hotel in Frederick within your budget.
  • Amenities: Looking for all the bells and whistles? Perhaps a full spa, a rooftop bar, maybe even concierge service? Get the perfect amenities for you.

Do you really want a fancy hotel loaded with extras? Of course you do. And you also deserve a sweet price on it. Book with us today and get that star-studded Frederick 4-star hotel and have enough cash in your pocket to spend at that secret superstar joint in the city. If you're looking to stay in one of the most popular rooms in our 1,668 Frederick hotels, book today because our top-selling rooms could be gone in a flash.