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Cambridge

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Cambridge Flights as Low as $152

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Wed, Aug 12 - Mon, Aug 17
DEN
Denver Intl.
DSM
Des Moines Intl.
$152 Roundtrip, found 5 hours ago
$152
Roundtrip
found 5 hours ago
Select Frontier Airlines flight, departing Wed, Aug 12 from Denver Intl. to Des Moines Intl., returning Mon, Aug 17, priced at $152 found 5 hours ago
Frontier Airlines
Wed, Jul 29 - Wed, Aug 5
AUS
Austin-Bergstrom Intl.
DSM
Des Moines Intl.
$226 Roundtrip, found 1 day ago
$226
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Wed, Jul 29 from Austin-Bergstrom Intl. to Des Moines Intl., returning Wed, Aug 5, priced at $226 found 1 day ago
Frontier Airlines
Wed, Jul 29 - Wed, Aug 5
SAN
San Diego Intl.
DSM
Des Moines Intl.
$248 Roundtrip, found 1 day ago
$248
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Wed, Jul 29 from San Diego Intl. to Des Moines Intl., returning Wed, Aug 5, priced at $248 found 1 day ago
Frontier Airlines
Mon, Aug 31 - Mon, Sep 14
LAX
Los Angeles Intl.
DSM
Des Moines Intl.
$250 Roundtrip, found 20 hours ago
$250
Roundtrip
found 20 hours ago
Select Frontier Airlines flight, departing Mon, Aug 31 from Los Angeles Intl. to Des Moines Intl., returning Mon, Sep 14, priced at $250 found 20 hours ago
Frontier Airlines
Fri, Sep 11 - Mon, Sep 14
PHX
Sky Harbor Intl.
DSM
Des Moines Intl.
$259 Roundtrip, found 5 hours ago
$259
Roundtrip
found 5 hours ago
Select Frontier Airlines flight, departing Fri, Sep 11 from Sky Harbor Intl. to Des Moines Intl., returning Mon, Sep 14, priced at $259 found 5 hours ago
Frontier Airlines
Wed, Jul 29 - Wed, Aug 5
DFW
Dallas-Fort Worth Intl.
DSM
Des Moines Intl.
$264 Roundtrip, found 5 hours ago
$264
Roundtrip
found 5 hours ago
Select Frontier Airlines flight, departing Wed, Jul 29 from Dallas-Fort Worth Intl. to Des Moines Intl., returning Wed, Aug 5, priced at $264 found 5 hours ago
Bargain Flight
Tue, Jul 21 - Wed, Jul 29
SAT
San Antonio Intl.
DSM
Des Moines Intl.
$266 Roundtrip, found 18 hours ago
$266
Roundtrip
found 18 hours ago
Select Bargain Flight flight, departing Tue, Jul 21 from San Antonio Intl. to Des Moines Intl., returning Wed, Jul 29, priced at $266 found 18 hours ago
Frontier Airlines
Wed, Aug 5 - Mon, Aug 17
ONT
Ontario Intl. Airport
DSM
Des Moines Intl.
$268 Roundtrip, found 20 hours ago
$268
Roundtrip
found 20 hours ago
Select Frontier Airlines flight, departing Wed, Aug 5 from Ontario Intl. Airport to Des Moines Intl., returning Mon, Aug 17, priced at $268 found 20 hours ago
Bargain Flight
Thu, Aug 20 - Mon, Aug 24
PHL
Philadelphia Intl.
DSM
Des Moines Intl.
$288 Roundtrip, found 1 day ago
$288
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Thu, Aug 20 from Philadelphia Intl. to Des Moines Intl., returning Mon, Aug 24, priced at $288 found 1 day ago
Bargain Flight
Thu, Oct 1 - Wed, Oct 21
DTW
Detroit Metropolitan Wayne County
DSM
Des Moines Intl.
$302 Roundtrip, found 1 day ago
$302
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Thu, Oct 1 from Detroit Metropolitan Wayne County to Des Moines Intl., returning Wed, Oct 21, priced at $302 found 1 day ago
American Airlines
Wed, Sep 16 - Tue, Sep 22
LFT
Lafayette Regional
DSM
Des Moines Intl.
$309 Roundtrip, found 1 day ago
$309
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Sep 16 from Lafayette Regional to Des Moines Intl., returning Tue, Sep 22, priced at $309 found 1 day ago
American Airlines
Thu, Aug 20 - Mon, Aug 24
TTN
Mercer
DSM
Des Moines Intl.
$376 Roundtrip, found 1 day ago
$376
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Aug 20 from Mercer to Des Moines Intl., returning Mon, Aug 24, priced at $376 found 1 day ago
Delta
Wed, Jul 8 - Sat, Jul 11
MDT
Harrisburg Intl.
DSM
Des Moines Intl.
$378 Roundtrip, found 1 day ago
$378
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Jul 8 from Harrisburg Intl. to Des Moines Intl., returning Sat, Jul 11, priced at $378 found 1 day ago
American Airlines
Sat, Jul 25 - Sun, Aug 2
CLD
McClellan-Palomar
DSM
Des Moines Intl.
$382 Roundtrip, found 2 days ago
$382
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Jul 25 from McClellan-Palomar to Des Moines Intl., returning Sun, Aug 2, priced at $382 found 2 days ago
United
Wed, Jul 15 - Tue, Jul 21
RDU
Raleigh - Durham Intl.
DSM
Des Moines Intl.
$397 Roundtrip, found 1 day ago
$397
Roundtrip
found 1 day ago
Select United flight, departing Wed, Jul 15 from Raleigh - Durham Intl. to Des Moines Intl., returning Tue, Jul 21, priced at $397 found 1 day ago
American Airlines
Thu, Jul 9 - Sat, Jul 18
BUF
Buffalo Niagara Intl.
DSM
Des Moines Intl.
$412 Roundtrip, found 1 day ago
$412
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Jul 9 from Buffalo Niagara Intl. to Des Moines Intl., returning Sat, Jul 18, priced at $412 found 1 day ago

Cheap Flights to Cambridge

Fall in love at first flight with your vacation to Cambridge by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Cambridge on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Cambridge, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Cambridge

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Cambridge with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the DSM airport.

What is the cheapest month to fly to Cambridge?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Cambridge are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Cambridge?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 13 to choose from for your flight to Cambridge.

What airport is best to fly into Cambridge?

When you’re planning your trip to Cambridge, convenience is the name of the game. Luckily, Cambridge Des Moines Intl. Airport is nearby so you can deplane and get going on checking off everything on your Cambridge must-do list.

How much are flights to Cambridge?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Cambridge on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $152, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Cambridge?

The trick to saving a stack of cash on your flight to Cambridge? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $152 right now, why wait?

Cambridge Flight Information
Destination airport
Des Moines Intl.
Destination airport IATA code
DSM
Roundtrip price
$151

Last Minute Hotel Deals in Cambridge

Ramada Tropics Resort & Conf Center by Wyndham Des Moines

Ramada Tropics Resort & Conf Center by Wyndham Des Moines

3 out of 5
5000 Merle Hay Rd Urbandale IA
Book a stay at this family-friendly hotel in Urbandale. Enjoy free WiFi, free parking, and a water park. Our guests praise the helpful staff and the clean rooms ...
5.8/10 (890 reviews)
"I thought the property was disgusting. Stained carpet. Left over food by the pool left out all night. While eating in the restaurant a mouse ran by us into the kitchen. The floor in the shower in my room was so slick I had to put a towel down so i didnt fall. We were told by the manager of the restaurant ..."

Reviewed on Jun 26, 2026

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Ramada Tropics Resort & Conf Center by Wyndham Des Moines
Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
Book a stay at this luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms ...
9.6/10 Exceptional! (1,207 reviews)
"Fantastic property and such a cool historical elegance. The staff is super helpful and the rooms are very clean, spacious and the perfect place to rest after a long travel day. Very conveniently located to food, Starbucks and sights."

Reviewed on Jun 26, 2026

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Hotel Fort Des Moines, Curio Collection by Hilton
Des Lux Hotel

Des Lux Hotel

3.5 out of 5
800 Locust St Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
9.8/10 Exceptional! (1,078 reviews)
"Great staff all the way around, wonderful morning breakfast served with a selection and plenty of room to dine. The hotel bar was excellent along with the lobby very well decorated and comfortable."

Reviewed on Jun 25, 2026

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Des Lux Hotel
Fairfield Inn & Suites by Marriott Des Moines Downtown

Fairfield Inn & Suites by Marriott Des Moines Downtown

4 out of 5
207 Crocker Street Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff ...
9/10 Wonderful! (462 reviews)
"We arrived after 1am and unfortunately Hotels.com only allows to book based on date, meaning because it was after midnight, we technically couldn't check-in til 3pm and it was 1am. Fortunately, the front desk worked with us and found an open room and accommodated our night stay. This was during the ..."

Reviewed on Jun 24, 2026

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Fairfield Inn & Suites by Marriott Des Moines Downtown
Stoney Creek Hotel Des Moines - Johnston

Stoney Creek Hotel Des Moines - Johnston

2.5 out of 5
5291 Stoney Creek Court Johnston IA
Book a stay at this business-friendly hotel in Johnston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.8/10 Excellent! (1,854 reviews)
"Always a wonderful stay, great staff ."

Reviewed on Jun 26, 2026

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Stoney Creek Hotel Des Moines - Johnston
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

3 out of 5
2650 University Ave. Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (1,002 reviews)
"The location of the hotel was perfect, easy and free parking. Nearby to restaurants and coffee shops. The room was comfy and a nice size. Very clean. The staff was very friendly and accessible. I would stay again."

Reviewed on Jun 23, 2026

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Home2 Suites by Hilton Des Moines at Drake University
Wildwood Lodge

Wildwood Lodge

3 out of 5
11431 Forest Ave Clive IA
Stay at this hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,232 reviews)
"Very pleasant overnight and breakfast. Would definitely recommend this hotel"

Reviewed on Jun 26, 2026

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Wildwood Lodge
Holiday Inn Downtown - Mercy Area by IHG

Holiday Inn Downtown - Mercy Area by IHG

3 out of 5
1050 6th Ave Des Moines IA
Stay at this hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff in our reviews. Popular ...
7.8/10 Good! (1,003 reviews)
"Very nice hotel close to the Casey’s Event Center. Thank you for the clean room and friendly atmosphere."

Reviewed on Jun 23, 2026

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Holiday Inn Downtown - Mercy Area by IHG
See all 769 properties in Cambridge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.