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Cambridge

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Cambridge Flights as Low as $138

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Allegiant Air
Thu, Oct 22 - Sun, Oct 25
FLL
Fort Lauderdale - Hollywood Intl.
DSM
Des Moines Intl.
$138 Roundtrip, found 2 days ago
$138
Roundtrip
found 2 days ago
Select Allegiant Air flight, departing Thu, Oct 22 from Fort Lauderdale - Hollywood Intl. to Des Moines Intl., returning Sun, Oct 25, priced at $138 found 2 days ago
Frontier Airlines
Thu, Nov 26 - Thu, Dec 3
DEN
Denver Intl.
DSM
Des Moines Intl.
$148 Roundtrip, found 10 hours ago
$148
Roundtrip
found 10 hours ago
Select Frontier Airlines flight, departing Thu, Nov 26 from Denver Intl. to Des Moines Intl., returning Thu, Dec 3, priced at $148 found 10 hours ago
Allegiant Air
Mon, Sep 14 - Fri, Sep 18
AZA
Phoenix - Mesa Gateway
DSM
Des Moines Intl.
$164 Roundtrip, found 5 days ago
$164
Roundtrip
found 5 days ago
Select Allegiant Air flight, departing Mon, Sep 14 from Phoenix - Mesa Gateway to Des Moines Intl., returning Fri, Sep 18, priced at $164 found 5 days ago
Bargain Flight
Fri, Oct 2 - Mon, Oct 12
CLE
Hopkins Intl.
DSM
Des Moines Intl.
$242 Roundtrip, found 10 hours ago
$242
Roundtrip
found 10 hours ago
Select Bargain Flight flight, departing Fri, Oct 2 from Hopkins Intl. to Des Moines Intl., returning Mon, Oct 12, priced at $242 found 10 hours ago
Frontier Airlines
Mon, Aug 31 - Mon, Sep 14
LAX
Los Angeles Intl.
DSM
Des Moines Intl.
$247 Roundtrip, found 7 hours ago
$247
Roundtrip
found 7 hours ago
Select Frontier Airlines flight, departing Mon, Aug 31 from Los Angeles Intl. to Des Moines Intl., returning Mon, Sep 14, priced at $247 found 7 hours ago
Frontier Airlines
Mon, Oct 12 - Mon, Oct 19
PHX
Sky Harbor Intl.
DSM
Des Moines Intl.
$254 Roundtrip, found 2 days ago
$254
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Mon, Oct 12 from Sky Harbor Intl. to Des Moines Intl., returning Mon, Oct 19, priced at $254 found 2 days ago
Frontier Airlines
Fri, Sep 18 - Mon, Sep 21
SAN
San Diego Intl.
DSM
Des Moines Intl.
$275 Roundtrip, found 10 hours ago
$275
Roundtrip
found 10 hours ago
Select Frontier Airlines flight, departing Fri, Sep 18 from San Diego Intl. to Des Moines Intl., returning Mon, Sep 21, priced at $275 found 10 hours ago
Bargain Flight
Sat, Sep 12 - Wed, Sep 16
MCO
Orlando Intl.
DSM
Des Moines Intl.
$280 Roundtrip, found 10 hours ago
$280
Roundtrip
found 10 hours ago
Select Bargain Flight flight, departing Sat, Sep 12 from Orlando Intl. to Des Moines Intl., returning Wed, Sep 16, priced at $280 found 10 hours ago
Bargain Flight
Mon, Nov 2 - Mon, Nov 16
SMF
Sacramento Intl.
DSM
Des Moines Intl.
$281 Roundtrip, found 15 hours ago
$281
Roundtrip
found 15 hours ago
Select Bargain Flight flight, departing Mon, Nov 2 from Sacramento Intl. to Des Moines Intl., returning Mon, Nov 16, priced at $281 found 15 hours ago
Bargain Flight
Sat, Sep 12 - Wed, Sep 16
DJT
President Donald J. Trump Intl. Airport
DSM
Des Moines Intl.
$287 Roundtrip, found 10 hours ago
$287
Roundtrip
found 10 hours ago
Select Bargain Flight flight, departing Sat, Sep 12 from President Donald J. Trump Intl. Airport to Des Moines Intl., returning Wed, Sep 16, priced at $287 found 10 hours ago
Bargain Flight
Wed, Sep 2 - Sun, Sep 6
AUS
Austin-Bergstrom Intl.
DSM
Des Moines Intl.
$291 Roundtrip, found 10 hours ago
$291
Roundtrip
found 10 hours ago
Select Bargain Flight flight, departing Wed, Sep 2 from Austin-Bergstrom Intl. to Des Moines Intl., returning Sun, Sep 6, priced at $291 found 10 hours ago
American Airlines
Wed, Nov 25 - Tue, Dec 8
CAE
Columbia Metropolitan
DSM
Des Moines Intl.
$295 Roundtrip, found 10 hours ago
$295
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Wed, Nov 25 from Columbia Metropolitan to Des Moines Intl., returning Tue, Dec 8, priced at $295 found 10 hours ago
Frontier Airlines
Mon, Sep 21 - Fri, Sep 25
SFO
San Francisco Intl.
DSM
Des Moines Intl.
$305 Roundtrip, found 4 days ago
$305
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Mon, Sep 21 from San Francisco Intl. to Des Moines Intl., returning Fri, Sep 25, priced at $305 found 4 days ago
Southwest Airlines
Tue, Sep 29 - Thu, Oct 8
PIT
Pittsburgh Intl.
DSM
Des Moines Intl.
$313 Roundtrip, found 10 hours ago
$313
Roundtrip
found 10 hours ago
Select Southwest Airlines flight, departing Tue, Sep 29 from Pittsburgh Intl. to Des Moines Intl., returning Thu, Oct 8, priced at $313 found 10 hours ago
United
Thu, Oct 8 - Sat, Oct 10
DAY
James M. Cox Dayton Intl.
DSM
Des Moines Intl.
$319 Roundtrip, found 15 hours ago
$319
Roundtrip
found 15 hours ago
Select United flight, departing Thu, Oct 8 from James M. Cox Dayton Intl. to Des Moines Intl., returning Sat, Oct 10, priced at $319 found 15 hours ago
American Airlines
Thu, Nov 26 - Tue, Dec 1
CHS
Charleston Intl.
DSM
Des Moines Intl.
$325 Roundtrip, found 10 hours ago
$325
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Thu, Nov 26 from Charleston Intl. to Des Moines Intl., returning Tue, Dec 1, priced at $325 found 10 hours ago

Cheap Flights to Cambridge

Fall in love at first flight with your vacation to Cambridge by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Cambridge on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Cambridge, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Cambridge

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Cambridge with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the DSM airport.

What is the cheapest month to fly to Cambridge?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Cambridge are in October, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Cambridge?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 11 to choose from for your flight to Cambridge.

What airport is best to fly into Cambridge?

When you’re planning your trip to Cambridge, convenience is the name of the game. Luckily, Cambridge Des Moines Intl. Airport is nearby so you can deplane and get going on checking off everything on your Cambridge must-do list.

How much are flights to Cambridge?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Cambridge on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $138, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Cambridge?

The trick to saving a stack of cash on your flight to Cambridge? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $138 right now, why wait?

Cambridge Flight Information
Destination airport
Des Moines Intl.
Destination airport IATA code
DSM
Roundtrip price
$138

Last Minute Hotel Deals in Cambridge

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
Book a stay at this luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms ...
9.6/10 Exceptional! (1,302 reviews)
"Amazing location and historic hotel. Great food and drink option , clean rooms ."

Reviewed on Aug 26, 2026

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Hotel Fort Des Moines, Curio Collection by Hilton
Ramada Tropics Resort & Conf Center by Wyndham Des Moines

Ramada Tropics Resort & Conf Center by Wyndham Des Moines

3 out of 5
5000 Merle Hay Rd Urbandale IA
Book a stay at this family-friendly hotel in Urbandale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Get rates
Ramada Tropics Resort & Conf Center by Wyndham Des Moines
Sonesta Essential Des Moines

Sonesta Essential Des Moines

2 out of 5
4755 Merle Hay Road Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
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Sonesta Essential Des Moines
Gateway Hotel and Conference Center at Iowa State University

Gateway Hotel and Conference Center at Iowa State University

3 out of 5
2100 Green Hills Drive Ames IA
Book a stay at this business-friendly hotel in Ames. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms ...
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Gateway Hotel and Conference Center at Iowa State University
Sheraton West Des Moines Hotel

Sheraton West Des Moines Hotel

3.5 out of 5
1800 50th St West Des Moines IA
Book a stay at this business-friendly hotel in West Des Moines. Enjoy breakfast (surcharge), room service, and a fitness center. Our guests praise the helpful ...
8.2/10 Very Good! (1,000 reviews)
"Its a great location to visit Des Moines and family!"

Reviewed on Aug 25, 2026

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Sheraton West Des Moines Hotel
Stoney Creek Hotel Des Moines - Johnston

Stoney Creek Hotel Des Moines - Johnston

2.5 out of 5
5291 Stoney Creek Court Johnston IA
Book a stay at this business-friendly hotel in Johnston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.8/10 Excellent! (1,877 reviews)
"My room was very musty. Bed felt damp. People before me put a car freshener on av unit. Sticky candy on floor, hair in bathtub. Told staff about it. Said they didn't have a room like mine available. I won't stay there again."

Reviewed on Aug 26, 2026

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Stoney Creek Hotel Des Moines - Johnston
GrandStay Hotel & Suites

GrandStay Hotel & Suites

2 out of 5
6215 Merle Hay Road Johnston IA
Stay at this hotel in Johnston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Iowa Gold Star Military Museum and Merle Hay Mall are ...
9.2/10 Wonderful! (781 reviews)
"Check in was smooth, friendly. Housekeeping staff encountered were great. Spacious, clean, nicely renovated room. Could use more lighting around mirror in the bathroom in order to see yourself for things like shaving, etc. Hotel well maintained inside and the grounds. My only complaint was the complimentary ..."

Reviewed on Aug 25, 2026

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GrandStay Hotel & Suites
La Quinta Inn & Suites by Wyndham Des Moines West Clive

La Quinta Inn & Suites by Wyndham Des Moines West Clive

3 out of 5
1390 Nw 118th St Clive IA
Book a stay at this family-friendly hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,029 reviews)
"The room was so hard to breath in with the air conditioner on. The filter or something needs to be changed. We all felt stuffy and sick after leaving. Breakfast was good though, and the pool was nice."

Reviewed on Aug 26, 2026

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La Quinta Inn & Suites by Wyndham Des Moines West Clive
See all 766 properties in Cambridge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.