Search Cheap Flights to
Cambridge

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Cambridge Flights as Low as $160

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Wed, May 21 - Fri, May 30
DEN
Denver Intl.
DSM
Des Moines Intl.
$160 Roundtrip, found 2 days ago
$160
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Wed, May 21 from Denver Intl. to Des Moines Intl., returning Fri, May 30, priced at $160 found 2 days ago
American Airlines
Tue, Jun 24 - Tue, Jul 22
PHX
Sky Harbor Intl.
DSM
Des Moines Intl.
$183 Roundtrip, found 3 days ago
$183
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Jun 24 from Sky Harbor Intl. to Des Moines Intl., returning Tue, Jul 22, priced at $183 found 3 days ago
Bargain Flight
Wed, Aug 13 - Tue, Aug 19
CLE
Hopkins Intl.
DSM
Des Moines Intl.
$200 Roundtrip, found 14 hours ago
$200
Roundtrip
found 14 hours ago
Select Bargain Flight flight, departing Wed, Aug 13 from Hopkins Intl. to Des Moines Intl., returning Tue, Aug 19, priced at $200 found 14 hours ago
Frontier Airlines
Mon, May 19 - Wed, May 21
DFW
Dallas-Fort Worth Intl.
DSM
Des Moines Intl.
$202 Roundtrip, found 3 days ago
$202
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Mon, May 19 from Dallas-Fort Worth Intl. to Des Moines Intl., returning Wed, May 21, priced at $202 found 3 days ago
Delta
Tue, Jul 22 - Tue, Jul 29
LAS
Harry Reid Intl.
DSM
Des Moines Intl.
$217 Roundtrip, found 1 day ago
$217
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Jul 22 from Harry Reid Intl. to Des Moines Intl., returning Tue, Jul 29, priced at $217 found 1 day ago
Bargain Flight
Wed, Sep 17 - Tue, Sep 30
SLC
Salt Lake City Intl.
DSM
Des Moines Intl.
$236 Roundtrip, found 16 hours ago
$236
Roundtrip
found 16 hours ago
Select Bargain Flight flight, departing Wed, Sep 17 from Salt Lake City Intl. to Des Moines Intl., returning Tue, Sep 30, priced at $236 found 16 hours ago
Delta
Tue, Aug 12 - Thu, Aug 14
PHL
Philadelphia Intl.
DSM
Des Moines Intl.
$237 Roundtrip, found 14 hours ago
$237
Roundtrip
found 14 hours ago
Select Delta flight, departing Tue, Aug 12 from Philadelphia Intl. to Des Moines Intl., returning Thu, Aug 14, priced at $237 found 14 hours ago
Frontier Airlines
Tue, May 6 - Fri, May 9
ATL
Hartsfield-Jackson Atlanta Intl.
DSM
Des Moines Intl.
$242 Roundtrip, found 4 days ago
$242
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Tue, May 6 from Hartsfield-Jackson Atlanta Intl. to Des Moines Intl., returning Fri, May 9, priced at $242 found 4 days ago
Delta
Sat, Jun 28 - Sat, Jul 5
MOB
Mobile Regional
DSM
Des Moines Intl.
$247 Roundtrip, found 1 day ago
$247
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Jun 28 from Mobile Regional to Des Moines Intl., returning Sat, Jul 5, priced at $247 found 1 day ago
Frontier Airlines
Sun, May 11 - Wed, May 21
SAT
San Antonio Intl.
DSM
Des Moines Intl.
$253 Roundtrip, found 11 hours ago
$253
Roundtrip
found 11 hours ago
Select Frontier Airlines flight, departing Sun, May 11 from San Antonio Intl. to Des Moines Intl., returning Wed, May 21, priced at $253 found 11 hours ago
Bargain Flight
Tue, Jun 24 - Wed, Jun 25
LGA
LaGuardia
DSM
Des Moines Intl.
$257 Roundtrip, found 1 day ago
$257
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Tue, Jun 24 from LaGuardia to Des Moines Intl., returning Wed, Jun 25, priced at $257 found 1 day ago
Bargain Flight
Sun, May 11 - Tue, May 13
BNA
Nashville Intl.
DSM
Des Moines Intl.
$262 Roundtrip, found 3 days ago
$262
Roundtrip
found 3 days ago
Select Bargain Flight flight, departing Sun, May 11 from Nashville Intl. to Des Moines Intl., returning Tue, May 13, priced at $262 found 3 days ago
Bargain Flight
Tue, Jun 3 - Sat, Jun 14
MCO
Orlando Intl.
DSM
Des Moines Intl.
$264 Roundtrip, found 1 hour ago
$264
Roundtrip
found 1 hour ago
Select Bargain Flight flight, departing Tue, Jun 3 from Orlando Intl. to Des Moines Intl., returning Sat, Jun 14, priced at $264 found 1 hour ago
Delta
Tue, Jun 24 - Wed, Jun 25
BWI
Baltimore Washington Intl. Thurgood Marshall
DSM
Des Moines Intl.
$271 Roundtrip, found 17 hours ago
$271
Roundtrip
found 17 hours ago
Select Delta flight, departing Tue, Jun 24 from Baltimore Washington Intl. Thurgood Marshall to Des Moines Intl., returning Wed, Jun 25, priced at $271 found 17 hours ago
Bargain Flight
Tue, May 13 - Tue, May 20
CLT
Charlotte-Douglas Intl.
DSM
Des Moines Intl.
$273 Roundtrip, found 1 day ago
$273
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Tue, May 13 from Charlotte-Douglas Intl. to Des Moines Intl., returning Tue, May 20, priced at $273 found 1 day ago
Delta
Wed, Jun 25 - Wed, Jul 9
PNS
Pensacola Intl.
DSM
Des Moines Intl.
$275 Roundtrip, found 1 day ago
$275
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Jun 25 from Pensacola Intl. to Des Moines Intl., returning Wed, Jul 9, priced at $275 found 1 day ago

Cheap Flights to Cambridge

Fall in love at first flight with your vacation to Cambridge by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Cambridge on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Cambridge, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Cambridge

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Cambridge with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the DSM airport.

What is the cheapest month to fly to Cambridge?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Cambridge are in May, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Cambridge?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 10 to choose from for your flight to Cambridge.

What airport is best to fly into Cambridge?

When you’re planning your trip to Cambridge, convenience is the name of the game. Luckily, Cambridge Des Moines Intl. Airport is nearby so you can deplane and get going on checking off everything on your Cambridge must-do list.

How much are flights to Cambridge?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Cambridge on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $160, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Cambridge?

The trick to saving a stack of cash on your flight to Cambridge? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $160 right now, why wait?

Cambridge Flight Information
Destination airport
Des Moines Intl.
Destination airport IATA code
DSM
Roundtrip price
$160

Last Minute Hotel Deals in Cambridge

Hotel Fort Des Moines, Curio Collection by Hilton
Hotel Fort Des Moines, Curio Collection by Hilton
4.5 out of 5
1000 Walnut St, Des Moines, IA
The price is $151 per night from Jun 1 to Jun 2
$151
includes taxes & fees
Jun 1 - Jun 2
Stay at this 4.5-star luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (979 reviews)
"The hotel was old, charming and in excellent condition. The staff was very friendly and attentive. The bed was comfortable and quiet. There were many restaurants with in walking distance. We are coming over to Hilton Honors from being IHG members for sometime, the IHG hotels are becoming expensive ..."

Reviewed on Apr 28, 2025

Hotel Fort Des Moines, Curio Collection by Hilton
Stoney Creek Hotel Des Moines - Johnston
Stoney Creek Hotel Des Moines - Johnston
2.5 out of 5
5291 Stoney Creek Court, Johnston, IA
The price is $122 per night from May 8 to May 9
$122
includes taxes & fees
May 8 - May 9
Book a stay at this business-friendly hotel in Johnston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.8/10 Excellent! (1,669 reviews)
"The room felt old and musty, poor lighting. We could smell the chlorine from the pool"

Reviewed on May 1, 2025

Stoney Creek Hotel Des Moines - Johnston
Surety Hotel
Surety Hotel
4 out of 5
206 6th Ave., Des Moines, IA
The price is $194 per night from May 18 to May 19
$194
includes taxes & fees
May 18 - May 19
Stay at this 4-star hotel in Des Moines. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the restaurant and the bar in our reviews. ...
9.2/10 Wonderful! (1,009 reviews)
"Sean was very helpful at the front desk and would return in the future - thank you!"

Reviewed on May 5, 2025

Surety Hotel
Sonesta Essential Des Moines
Sonesta Essential Des Moines
2 out of 5
4755 Merle Hay Road, Des Moines, IA
The price is $88 per night from May 12 to May 13
$88
includes taxes & fees
May 12 - May 13
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
7.2/10 Good! (1,003 reviews)
"It was ok"

Reviewed on May 3, 2025

Sonesta Essential Des Moines
Revel Hotel Des Moines Urbandale, Tapestry Collection by Hilton
Revel Hotel Des Moines Urbandale, Tapestry Collection by Hilton
4.5 out of 5
11211 Hickman Rd, Urbandale, IA
The price is $151 per night from May 12 to May 13
$151
includes taxes & fees
May 12 - May 13
Book a stay at this luxury hotel in Urbandale. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (515 reviews)
"Very clean. Very quiet. Staff was very friend. Room was modern and nice."

Reviewed on May 3, 2025

Revel Hotel Des Moines Urbandale, Tapestry Collection by Hilton
Des Lux Hotel
Des Lux Hotel
3.5 out of 5
800 Locust St, Des Moines, IA
The price is $200 per night from May 6 to May 7
$200
includes taxes & fees
May 6 - May 7
Stay at this 3.5-star business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and ...
9.6/10 Exceptional! (1,003 reviews)
"Awesome staff!"

Reviewed on May 2, 2025

Des Lux Hotel
Wildwood Lodge
Wildwood Lodge
3 out of 5
11431 Forest Ave, Clive, IA
The price is $122 per night from May 7 to May 8
$122
includes taxes & fees
May 7 - May 8
Stay at this 3-star hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.4/10 Exceptional! (1,234 reviews)
"Clean, super cute, love the decor! The pool was fun! Great location- close to restaurants!"

Reviewed on May 3, 2025

Wildwood Lodge
Quality Inn & Suites Des Moines - Merle Hay Road
Quality Inn & Suites Des Moines - Merle Hay Road
2.5 out of 5
4995 Merle Hay Rd, Des Moines, IA
The price is $64 per night from May 11 to May 12
$64
includes taxes & fees
May 11 - May 12
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.4/10 Good! (860 reviews)
"The room was fine, except for the furniture which looked a little bit outdated. Also, pillows were not as nice as in many other places, but they were all comfortable. Overall, good place for the money. Breakfast was limited but good enough."

Reviewed on Apr 30, 2025

Quality Inn & Suites Des Moines - Merle Hay Road
See all 668 properties in Cambridge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.