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Cambridge

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Cambridge Flights as Low as $120

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Wed, Mar 25 - Mon, Mar 30
DEN
Denver Intl.
DSM
Des Moines Intl.
$120 Roundtrip, found 12 hours ago
$120
Roundtrip
found 12 hours ago
Select Frontier Airlines flight, departing Wed, Mar 25 from Denver Intl. to Des Moines Intl., returning Mon, Mar 30, priced at $120 found 12 hours ago
Frontier Airlines
Thu, Mar 12 - Fri, Mar 20
MCO
Orlando Intl.
DSM
Des Moines Intl.
$122 Roundtrip, found 4 days ago
$122
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Thu, Mar 12 from Orlando Intl. to Des Moines Intl., returning Fri, Mar 20, priced at $122 found 4 days ago
American Airlines
Fri, Apr 17 - Mon, Apr 20
IAH
George Bush Intercontinental
DSM
Des Moines Intl.
$174 Roundtrip, found 6 hours ago
$174
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Fri, Apr 17 from George Bush Intercontinental to Des Moines Intl., returning Mon, Apr 20, priced at $174 found 6 hours ago
Bargain Flight
Fri, Apr 3 - Fri, Apr 24
DTW
Detroit Metropolitan Wayne County
DSM
Des Moines Intl.
$203 Roundtrip, found 20 hours ago
$203
Roundtrip
found 20 hours ago
Select Bargain Flight flight, departing Fri, Apr 3 from Detroit Metropolitan Wayne County to Des Moines Intl., returning Fri, Apr 24, priced at $203 found 20 hours ago
Frontier Airlines
Fri, Mar 13 - Sat, Mar 21
PHX
Sky Harbor Intl.
DSM
Des Moines Intl.
$206 Roundtrip, found 4 days ago
$206
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Fri, Mar 13 from Sky Harbor Intl. to Des Moines Intl., returning Sat, Mar 21, priced at $206 found 4 days ago
Frontier Airlines
Mon, Apr 13 - Fri, Apr 24
SAN
San Diego Intl.
DSM
Des Moines Intl.
$211 Roundtrip, found 21 hours ago
$211
Roundtrip
found 21 hours ago
Select Frontier Airlines flight, departing Mon, Apr 13 from San Diego Intl. to Des Moines Intl., returning Fri, Apr 24, priced at $211 found 21 hours ago
Frontier Airlines
Thu, Apr 2 - Mon, Apr 13
ELP
El Paso Intl.
DSM
Des Moines Intl.
$212 Roundtrip, found 2 days ago
$212
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Thu, Apr 2 from El Paso Intl. to Des Moines Intl., returning Mon, Apr 13, priced at $212 found 2 days ago
Frontier Airlines
Sat, Mar 14 - Wed, Mar 25
CLT
Charlotte-Douglas Intl.
DSM
Des Moines Intl.
$246 Roundtrip, found 2 days ago
$246
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Sat, Mar 14 from Charlotte-Douglas Intl. to Des Moines Intl., returning Wed, Mar 25, priced at $246 found 2 days ago
United
Wed, Jun 24 - Sat, Jul 4
GUC
Gunnison-Crested Butte Regional
DSM
Des Moines Intl.
$251 Roundtrip, found 1 hour ago
$251
Roundtrip
found 1 hour ago
Select United flight, departing Wed, Jun 24 from Gunnison-Crested Butte Regional to Des Moines Intl., returning Sat, Jul 4, priced at $251 found 1 hour ago
American Airlines
Wed, Mar 25 - Mon, Apr 6
LAX
Los Angeles Intl.
DSM
Des Moines Intl.
$253 Roundtrip, found 17 hours ago
$253
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Wed, Mar 25 from Los Angeles Intl. to Des Moines Intl., returning Mon, Apr 6, priced at $253 found 17 hours ago
Bargain Flight
Fri, Apr 17 - Mon, Apr 20
DFW
Dallas-Fort Worth Intl.
DSM
Des Moines Intl.
$261 Roundtrip, found 6 hours ago
$261
Roundtrip
found 6 hours ago
Select Bargain Flight flight, departing Fri, Apr 17 from Dallas-Fort Worth Intl. to Des Moines Intl., returning Mon, Apr 20, priced at $261 found 6 hours ago
Frontier Airlines
Sun, Mar 15 - Tue, Mar 17
ATL
Hartsfield-Jackson Atlanta Intl.
DSM
Des Moines Intl.
$270 Roundtrip, found 2 days ago
$270
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Sun, Mar 15 from Hartsfield-Jackson Atlanta Intl. to Des Moines Intl., returning Tue, Mar 17, priced at $270 found 2 days ago
Delta
Wed, Mar 25 - Fri, Apr 10
HOU
William P. Hobby
DSM
Des Moines Intl.
$278 Roundtrip, found 7 hours ago
$278
Roundtrip
found 7 hours ago
Select Delta flight, departing Wed, Mar 25 from William P. Hobby to Des Moines Intl., returning Fri, Apr 10, priced at $278 found 7 hours ago
Bargain Flight
Sat, May 2 - Sat, May 9
CLD
McClellan-Palomar
DSM
Des Moines Intl.
$280 Roundtrip, found 17 hours ago
$280
Roundtrip
found 17 hours ago
Select Bargain Flight flight, departing Sat, May 2 from McClellan-Palomar to Des Moines Intl., returning Sat, May 9, priced at $280 found 17 hours ago
United
Wed, Apr 1 - Mon, Apr 6
EWR
Newark Liberty Intl. Airport
DSM
Des Moines Intl.
$306 Roundtrip, found 5 days ago
$306
Roundtrip
found 5 days ago
Select United flight, departing Wed, Apr 1 from Newark Liberty Intl. Airport to Des Moines Intl., returning Mon, Apr 6, priced at $306 found 5 days ago
Frontier Airlines
Mon, Jul 13 - Mon, Jul 20
CVG
Cincinnati - Northern Kentucky Intl.
DSM
Des Moines Intl.
$319 Roundtrip, found 7 hours ago
$319
Roundtrip
found 7 hours ago
Select Frontier Airlines flight, departing Mon, Jul 13 from Cincinnati - Northern Kentucky Intl. to Des Moines Intl., returning Mon, Jul 20, priced at $319 found 7 hours ago

Cheap Flights to Cambridge

Fall in love at first flight with your vacation to Cambridge by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Cambridge on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Cambridge, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Cambridge

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Cambridge with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the DSM airport.

What is the cheapest month to fly to Cambridge?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Cambridge are in March, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Cambridge?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 13 to choose from for your flight to Cambridge.

What airport is best to fly into Cambridge?

When you’re planning your trip to Cambridge, convenience is the name of the game. Luckily, Cambridge Des Moines Intl. Airport is nearby so you can deplane and get going on checking off everything on your Cambridge must-do list.

How much are flights to Cambridge?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Cambridge on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $120, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Cambridge?

The trick to saving a stack of cash on your flight to Cambridge? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $120 right now, why wait?

Cambridge Flight Information
Destination airport
Des Moines Intl.
Destination airport IATA code
DSM
Roundtrip price
$119

Last Minute Hotel Deals in Cambridge

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
Book a stay at this luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms ...
9.6/10 Exceptional! (1,091 reviews)
We enjoyed our stay at the Hotel Fort Des Moines. Room was comfortable and clean. The restaurants, both Proudfoot and Hibnob, were great. The bartender at Proudfoot was the best!

Reviewed on Mar 9, 2026

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Hotel Fort Des Moines, Curio Collection by Hilton
Des Lux Hotel

Des Lux Hotel

3.5 out of 5
800 Locust St Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
9.8/10 Exceptional! (1,040 reviews)
The hotel amenities and staff were excellent! From 10:00 PM to 3 AM. There was nonstop street racing that was so loud I thought they were in my room. I did not sleep at all! When I mentioned it to the front desk at check out they said “yeah it happens all the time. You should’ve called the police”. ...

Reviewed on Mar 9, 2026

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Des Lux Hotel
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

3 out of 5
2650 University Ave. Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (1,011 reviews)
Breakfast not good, tv had issues

Reviewed on Mar 9, 2026

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Home2 Suites by Hilton Des Moines at Drake University
Wildwood Lodge

Wildwood Lodge

3 out of 5
11431 Forest Ave Clive IA
Stay at this hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,238 reviews)
This was great they had a gym and the room was clean. Only thing was the Lighting wasn’t very good but it was a great stay. Breakfast was great too!

Reviewed on Mar 9, 2026

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Wildwood Lodge
Holiday Inn Downtown - Mercy Area by IHG

Holiday Inn Downtown - Mercy Area by IHG

3 out of 5
1050 6th Ave Des Moines IA
Stay at this hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff in our reviews. Popular ...
7.8/10 Good! (1,006 reviews)
Clean room

Reviewed on Mar 8, 2026

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Holiday Inn Downtown - Mercy Area by IHG
Stoney Creek Hotel Des Moines - Johnston

Stoney Creek Hotel Des Moines - Johnston

2.5 out of 5
5291 Stoney Creek Court Johnston IA
Book a stay at this business-friendly hotel in Johnston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.8/10 Excellent! (1,846 reviews)
Pool room heater was broken. Water temps were a bit chilly but the room it's self was freezing. Very noisy property-.kids running up and down the halls all night. Staff was rude and property was run down . .

Reviewed on Mar 10, 2026

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Stoney Creek Hotel Des Moines - Johnston
Gateway Hotel and Conference Center at Iowa State University

Gateway Hotel and Conference Center at Iowa State University

3 out of 5
2100 Green Hills Drive Ames IA
Book a stay at this business-friendly hotel in Ames. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms ...
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Gateway Hotel and Conference Center at Iowa State University
Ramada Tropics Resort & Conf Center by Wyndham Des Moines

Ramada Tropics Resort & Conf Center by Wyndham Des Moines

3 out of 5
5000 Merle Hay Rd Urbandale IA
Book a stay at this family-friendly hotel in Urbandale. Enjoy free WiFi, free parking, and a water park. Our guests praise the helpful staff and the clean rooms ...
5.6/10 (744 reviews)
The room was handed over late, plus there was a bad smell and the shower water was very cold.

Reviewed on Mar 9, 2026

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Ramada Tropics Resort & Conf Center by Wyndham Des Moines
See all 761 properties in Cambridge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.