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O Brien

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O Brien Flights as Low as $102

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Breeze Airways
Tue, Sep 8 - Tue, Sep 15
FLL
Fort Lauderdale - Hollywood Intl.
TLH
Tallahassee Intl.
$102 Roundtrip, found 3 days ago
$102
Roundtrip
found 3 days ago
Select Breeze Airways flight, departing Tue, Sep 8 from Fort Lauderdale - Hollywood Intl. to Tallahassee Intl., returning Tue, Sep 15, priced at $102 found 3 days ago
Breeze Airways
Tue, Sep 8 - Tue, Sep 15
FLL
Fort Lauderdale - Hollywood Intl.
TLH
Tallahassee Intl.
$107 Roundtrip, found 3 days ago
$107
Roundtrip
found 3 days ago
Select Breeze Airways flight, departing Tue, Sep 8 from Fort Lauderdale - Hollywood Intl. to Tallahassee Intl., returning Tue, Sep 15, priced at $107 found 3 days ago
Breeze Airways
Tue, Sep 8 - Tue, Sep 15
FLL
Fort Lauderdale - Hollywood Intl.
TLH
Tallahassee Intl.
$112 Roundtrip, found 3 days ago
$112
Roundtrip
found 3 days ago
Select Breeze Airways flight, departing Tue, Sep 8 from Fort Lauderdale - Hollywood Intl. to Tallahassee Intl., returning Tue, Sep 15, priced at $112 found 3 days ago
Frontier Airlines
Fri, May 1 - Sun, May 3
FLL
Fort Lauderdale - Hollywood Intl.
JAX
Jacksonville Intl.
$160 Roundtrip, found 5 days ago
$160
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Fri, May 1 from Fort Lauderdale - Hollywood Intl. to Jacksonville Intl., returning Sun, May 3, priced at $160 found 5 days ago
Frontier Airlines
Fri, May 1 - Sun, May 3
FLL
Fort Lauderdale - Hollywood Intl.
JAX
Jacksonville Intl.
$183 Roundtrip, found 5 days ago
$183
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Fri, May 1 from Fort Lauderdale - Hollywood Intl. to Jacksonville Intl., returning Sun, May 3, priced at $183 found 5 days ago
Frontier Airlines
Mon, Apr 13 - Fri, Apr 17
PHL
Philadelphia Intl.
JAX
Jacksonville Intl.
$184 Roundtrip, found 11 hours ago
$184
Roundtrip
found 11 hours ago
Select Frontier Airlines flight, departing Mon, Apr 13 from Philadelphia Intl. to Jacksonville Intl., returning Fri, Apr 17, priced at $184 found 11 hours ago
Delta
Fri, May 1 - Sun, May 3
FLL
Fort Lauderdale - Hollywood Intl.
JAX
Jacksonville Intl.
$192 Roundtrip, found 5 days ago
$192
Roundtrip
found 5 days ago
Select Delta flight, departing Fri, May 1 from Fort Lauderdale - Hollywood Intl. to Jacksonville Intl., returning Sun, May 3, priced at $192 found 5 days ago
JetBlue Airways
Tue, Mar 17 - Tue, Mar 24
FLL
Fort Lauderdale - Hollywood Intl.
JAX
Jacksonville Intl.
$228 Roundtrip, found 4 days ago
$228
Roundtrip
found 4 days ago
Select JetBlue Airways flight, departing Tue, Mar 17 from Fort Lauderdale - Hollywood Intl. to Jacksonville Intl., returning Tue, Mar 24, priced at $228 found 4 days ago
Frontier Airlines
Wed, May 6 - Tue, May 19
MKE
General Mitchell Intl.
JAX
Jacksonville Intl.
$260 Roundtrip, found 19 hours ago
$260
Roundtrip
found 19 hours ago
Select Frontier Airlines flight, departing Wed, May 6 from General Mitchell Intl. to Jacksonville Intl., returning Tue, May 19, priced at $260 found 19 hours ago
Bargain Flight
Tue, Apr 14 - Tue, Apr 21
MKE
General Mitchell Intl.
JAX
Jacksonville Intl.
$268 Roundtrip, found 15 hours ago
$268
Roundtrip
found 15 hours ago
Select Bargain Flight flight, departing Tue, Apr 14 from General Mitchell Intl. to Jacksonville Intl., returning Tue, Apr 21, priced at $268 found 15 hours ago
American Airlines
Tue, Apr 21 - Sat, Apr 25
FLL
Fort Lauderdale - Hollywood Intl.
TLH
Tallahassee Intl.
$291 Roundtrip, found 4 days ago
$291
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Apr 21 from Fort Lauderdale - Hollywood Intl. to Tallahassee Intl., returning Sat, Apr 25, priced at $291 found 4 days ago
American Airlines
Tue, May 19 - Wed, May 27
TTN
Mercer
JAX
Jacksonville Intl.
$309 Roundtrip, found 5 days ago
$309
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, May 19 from Mercer to Jacksonville Intl., returning Wed, May 27, priced at $309 found 5 days ago
Delta
Wed, May 13 - Wed, May 20
FLL
Fort Lauderdale - Hollywood Intl.
GNV
Gainesville Regional
$385 Roundtrip, found 3 days ago
$385
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, May 13 from Fort Lauderdale - Hollywood Intl. to Gainesville Regional, returning Wed, May 20, priced at $385 found 3 days ago
American Airlines
Tue, Aug 11 - Sat, Aug 15
PHL
Philadelphia Intl.
TLH
Tallahassee Intl.
$401 Roundtrip, found 3 days ago
$401
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Aug 11 from Philadelphia Intl. to Tallahassee Intl., returning Sat, Aug 15, priced at $401 found 3 days ago
Delta
Tue, Apr 14 - Mon, Apr 27
MKE
General Mitchell Intl.
GNV
Gainesville Regional
$441 Roundtrip, found 9 hours ago
$441
Roundtrip
found 9 hours ago
Select Delta flight, departing Tue, Apr 14 from General Mitchell Intl. to Gainesville Regional, returning Mon, Apr 27, priced at $441 found 9 hours ago
Delta
Mon, Apr 13 - Mon, Apr 13
PHL
Philadelphia Intl.
GNV
Gainesville Regional
$671 Roundtrip, found 22 hours ago
$671
Roundtrip
found 22 hours ago
Select Delta flight, departing Mon, Apr 13 from Philadelphia Intl. to Gainesville Regional, returning Mon, Apr 13, priced at $671 found 22 hours ago

Cheap Flights to O Brien

Fall in love at first flight with your vacation to O Brien by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to O Brien on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in O Brien, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to O Brien

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to O Brien with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the null airport.

What is the cheapest month to fly to O Brien?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to O Brien are in September, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to O Brien?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to O Brien.

What airport is best to fly into O Brien?

When you’re planning your trip to O Brien, convenience is the name of the game. Luckily, O Brien Gainesville Regional Airport is nearby so you can deplane and get going on checking off everything on your O Brien must-do list.

How much are flights to O Brien?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to O Brien on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $102, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to O Brien?

The trick to saving a stack of cash on your flight to O Brien? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $102 right now, why wait?

O Brien Flight Information
Destination airport
Tallahassee Intl.
Destination airport IATA code
TLH
Roundtrip price
$101

Last Minute Hotel Deals in O Brien

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

3.5 out of 5
16367 NW 167TH BLVD Alachua FL
Book a stay at this business-friendly hotel in Alachua. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,002 reviews)
It was friendly. I didn’t use the hot tub.

Reviewed on Mar 13, 2026

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Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City

2.5 out of 5
165NW CALI DRIVE Lake City FL
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,078 reviews)
Very clean room, staff and front desk extremely friendly!

Reviewed on Mar 12, 2026

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La Quinta Inn & Suite by Wyndham Lake City
Best Western Plus Lake City

Best Western Plus Lake City

2.5 out of 5
350 SW Florida Gateway Dr Lake City FL
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,022 reviews)
Clean room, easy check in/out, friendly staff, friendly staff, simple but delicious breakfast.

Reviewed on Mar 13, 2026

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Best Western Plus Lake City
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

2 out of 5
1699 NE Co Rd 337 High Springs FL
Stay at this cabin in High Springs. Enjoy free parking, patios, and climate control. Popular attractions Ruth B. Kirby Gilchrist Blue Springs State Park and ...
Get rates
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
Holiday Inn Express & Suites Live Oak by IHG

Holiday Inn Express & Suites Live Oak by IHG

2.5 out of 5
6694 Us Highway 129 Live Oak FL
Book a stay at this business-friendly hotel in Live Oak. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (807 reviews)
The TV was improperly installed and virtually unusable. The furniture was strangely shaped/uncomfortable. The phone and coffee maker were both broken.

Reviewed on Mar 12, 2026

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Holiday Inn Express & Suites Live Oak by IHG
Americas Best Value Inn Lake City

Americas Best Value Inn Lake City

2 out of 5
3835 West US Highway 90 Lake City FL
Stay at this motel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8.6/10 Excellent! (1,007 reviews)
The rooms with a king bed are bigger than the double beds. Hotel is clean & staff is super friendly. The 2 hotels across the streets around it are sketchy but overall enjoyed the stay both nights with absolutely no problems.

Reviewed on Mar 14, 2026

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Americas Best Value Inn Lake City
Tru by Hilton Lake City

Tru by Hilton Lake City

2.5 out of 5
284 NW Centurion Court Lake City FL
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,004 reviews)
Great

Reviewed on Mar 14, 2026

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Tru by Hilton Lake City
Comfort Suites Lake City

Comfort Suites Lake City

2.5 out of 5
3690 W Us Highway 90 Lake City FL
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,005 reviews)
Needs a lot of TLC. Breakfast was pretty pitiful. Most of our party skipped breakfast and we got something down the road.

Reviewed on Mar 11, 2026

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Comfort Suites Lake City
See all 368 properties in O Brien
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.