Search Cheap Flights to
O Brien

Name: Quality Inn Lake City
Price range: $85
Rating: 7.6

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O Brien Flights as Low as $120

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

All deals

One way

Roundtrip

Sat, Mar 1 - Tue, Mar 4

ATL

Hartsfield-Jackson Atlanta Intl.

JAX

Jacksonville Intl.

$120

Roundtrip

found 3 days ago

Fri, Feb 28 - Tue, Mar 4

ATL

Hartsfield-Jackson Atlanta Intl.

JAX

Jacksonville Intl.

$130

Roundtrip

found 3 days ago

Tue, Mar 18 - Mon, Mar 24

DCA

Ronald Reagan Washington National

JAX

Jacksonville Intl.

$134

Roundtrip

found 4 days ago

Mon, Mar 3 - Thu, Mar 6

ATL

Hartsfield-Jackson Atlanta Intl.

JAX

Jacksonville Intl.

$140

Roundtrip

found 3 days ago

Fri, Feb 28 - Tue, Mar 4

ATL

Hartsfield-Jackson Atlanta Intl.

JAX

Jacksonville Intl.

$150

Roundtrip

found 6 days ago

Mon, Mar 17 - Sat, Mar 22

ATL

Hartsfield-Jackson Atlanta Intl.

JAX

Jacksonville Intl.

$161

Roundtrip

found 1 day ago

Tue, Mar 18 - Tue, Mar 25

DCA

Ronald Reagan Washington National

JAX

Jacksonville Intl.

$199

Roundtrip

found 12 hours ago

Sat, Mar 15 - Tue, Mar 18

DCA

Ronald Reagan Washington National

JAX

Jacksonville Intl.

$218

Roundtrip

found 4 days ago

Sat, Feb 22 - Mon, Feb 24

DCA

Ronald Reagan Washington National

JAX

Jacksonville Intl.

$234

Roundtrip

found 1 day ago

Tue, Mar 18 - Tue, Mar 25

BWI

Baltimore Washington Intl. Thurgood Marshall

JAX

Jacksonville Intl.

$257

Roundtrip

found 19 hours ago

Sat, Feb 22 - Mon, Feb 24

DCA

Ronald Reagan Washington National

JAX

Jacksonville Intl.

$319

Roundtrip

found 1 day ago

Wed, Apr 9 - Thu, Apr 17

DCA

Ronald Reagan Washington National

TLH

Tallahassee Intl.

$336

Roundtrip

found 3 days ago

Sat, Feb 22 - Sat, Feb 22

BWI

Baltimore Washington Intl. Thurgood Marshall

GNV

Gainesville Regional

$384

Roundtrip

found 3 days ago

Tue, Feb 18 - Wed, Feb 19

BWI

Baltimore Washington Intl. Thurgood Marshall

TLH

Tallahassee Intl.

$390

Roundtrip

found 5 days ago

Mon, Feb 24 - Tue, Mar 4

ATL

Hartsfield-Jackson Atlanta Intl.

GNV

Gainesville Regional

$399

Roundtrip

found 6 days ago

Fri, Feb 28 - Sun, Mar 2

ATL

Hartsfield-Jackson Atlanta Intl.

TLH

Tallahassee Intl.

$421

Roundtrip

found 3 days ago

Cheap Flights to O Brien

Fall in love at first flight with your vacation to O Brien by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to O Brien on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in O Brien, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to O Brien

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to O Brien with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the null airport.

What is the cheapest month to fly to O Brien?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to O Brien are in March, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to O Brien?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to O Brien.

What airport is best to fly into O Brien?

When you’re planning your trip to O Brien, convenience is the name of the game. Luckily, O Brien Gainesville Regional Airport is nearby so you can deplane and get going on checking off everything on your O Brien must-do list.

How much are flights to O Brien?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to O Brien on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $120, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to O Brien?

The trick to saving a stack of cash on your flight to O Brien? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $120 right now, why wait?

O Brien Flight Information
Destination airport	Jacksonville Intl.
Destination airport IATA code	JAX
Roundtrip price	$120

Last Minute Hotel Deals in O Brien

La Quinta Inn & Suite by Wyndham Lake City

165NW CALI DRIVE, Lake City, FL

$114

includes taxes & fees

Feb 23 - Feb 24

Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...

8.8/10 Excellent! (1,005 reviews)

"Easy access to Interstate"

Reviewed on Feb 14, 2025

Americas Best Value Inn Lake City

3835 West US Highway 90, Lake City, FL

$80

includes taxes & fees

Feb 18 - Feb 19

Stay at this motel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...

8.6/10 Excellent! (1,011 reviews)

"We had a great experience. The staff was wonderful. The room was small but very clean. Even the grounds were spotless! The packed bag breakfast was a nice touch as well. Would definitely stay ther again!"

Reviewed on Feb 16, 2025

Best Western Plus Lake City

350 SW Florida Gateway Dr, Lake City, FL

$133

includes taxes & fees

Feb 23 - Feb 24

Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...

9.2/10 Wonderful! (1,007 reviews)

"Clean, quiet and comfortable. Staff were very friendly and helpful."

Reviewed on Feb 13, 2025

Holiday Inn Express & Suites Alachua - Gainesville Area, an IHG Hotel

16367 NW 167TH BLVD, Alachua, FL

$149

includes taxes & fees

Feb 19 - Feb 20

Stay at this 3.5-star business-friendly hotel in Alachua. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...

9.2/10 Wonderful! (1,003 reviews)

"Property was at a great location. Off the highway, 20-25 mins to local springs and convenient with local food places. Price was reasonable during the time I went and being last min planning same day booking."

Reviewed on Feb 14, 2025

TownePlace Suites by Marriott Lake City

178 NW COMMERCE DR, Lake City, FL

$173

includes taxes & fees

Feb 18 - Feb 19

Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Lake City Mall and Southside ...

10/10 Exceptional! (17 reviews)

"Very nice"

Reviewed on Feb 16, 2025

Postcard Cabins Gilchrist Springs

1699 NE Co Rd 337, High Springs, FL

$110

includes taxes & fees

Mar 10 - Mar 11

Stay at this cabin in High Springs. Enjoy free parking, patios, and climate control. Popular attractions Ruth B. Kirby Gilchrist Blue Springs State Park and ...

10/10 Exceptional! (7 reviews)

"Nice clean"

Reviewed on Feb 15, 2025

Holiday Inn & Suites Lake City, an IHG Hotel

213 Sw Commerce Dr, Lake City, FL

$107

includes taxes & fees

Feb 23 - Feb 24

Stay at this 3-star business-friendly hotel in Lake City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...

8.4/10 Very Good! (1,001 reviews)

"Hotel was great for my needs, which was to break up a long driving trip."

Reviewed on Feb 10, 2025

Quality Inn Lake City

285 Sw Commerce Dr, Lake City, FL

$85

includes taxes & fees

Mar 2 - Mar 3

Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

7.6/10 Good! (824 reviews)

"Great stay. Best in the area."

Reviewed on Jan 31, 2025

See all 300 properties in O Brien

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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