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O Brien

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O Brien Flights as Low as $237

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Sun Country Airlines
Mon, Jul 13 - Mon, Jul 20
MSP
Minneapolis - St. Paul Intl.
JAX
Jacksonville Intl.
$237 Roundtrip, found 3 days ago
$237
Roundtrip
found 3 days ago
Select Sun Country Airlines flight, departing Mon, Jul 13 from Minneapolis - St. Paul Intl. to Jacksonville Intl., returning Mon, Jul 20, priced at $237 found 3 days ago
Sun Country Airlines
Mon, Jul 13 - Mon, Jul 20
MSP
Minneapolis - St. Paul Intl.
JAX
Jacksonville Intl.
$342 Roundtrip, found 3 days ago
$342
Roundtrip
found 3 days ago
Select Sun Country Airlines flight, departing Mon, Jul 13 from Minneapolis - St. Paul Intl. to Jacksonville Intl., returning Mon, Jul 20, priced at $342 found 3 days ago
Delta
Mon, Jul 13 - Mon, Jul 20
MSP
Minneapolis - St. Paul Intl.
JAX
Jacksonville Intl.
$352 Roundtrip, found 3 days ago
$352
Roundtrip
found 3 days ago
Select Delta flight, departing Mon, Jul 13 from Minneapolis - St. Paul Intl. to Jacksonville Intl., returning Mon, Jul 20, priced at $352 found 3 days ago
Delta
Tue, Jun 30 - Wed, Jul 15
MSP
Minneapolis - St. Paul Intl.
GNV
Gainesville Regional
$359 Roundtrip, found 1 day ago
$359
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Jun 30 from Minneapolis - St. Paul Intl. to Gainesville Regional, returning Wed, Jul 15, priced at $359 found 1 day ago
Delta
Mon, Jul 13 - Mon, Jul 20
MSP
Minneapolis - St. Paul Intl.
JAX
Jacksonville Intl.
$362 Roundtrip, found 3 days ago
$362
Roundtrip
found 3 days ago
Select Delta flight, departing Mon, Jul 13 from Minneapolis - St. Paul Intl. to Jacksonville Intl., returning Mon, Jul 20, priced at $362 found 3 days ago
American Airlines
Mon, Jul 13 - Mon, Jul 20
MSP
Minneapolis - St. Paul Intl.
JAX
Jacksonville Intl.
$392 Roundtrip, found 3 days ago
$392
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Jul 13 from Minneapolis - St. Paul Intl. to Jacksonville Intl., returning Mon, Jul 20, priced at $392 found 3 days ago
American Airlines
Mon, Jul 13 - Mon, Jul 20
MSP
Minneapolis - St. Paul Intl.
JAX
Jacksonville Intl.
$407 Roundtrip, found 3 days ago
$407
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Jul 13 from Minneapolis - St. Paul Intl. to Jacksonville Intl., returning Mon, Jul 20, priced at $407 found 3 days ago
Delta
Thu, Jul 9 - Wed, Jul 15
MSP
Minneapolis - St. Paul Intl.
JAX
Jacksonville Intl.
$408 Roundtrip, found 4 days ago
$408
Roundtrip
found 4 days ago
Select Delta flight, departing Thu, Jul 9 from Minneapolis - St. Paul Intl. to Jacksonville Intl., returning Wed, Jul 15, priced at $408 found 4 days ago
Delta
Mon, Jul 13 - Mon, Jul 20
MSP
Minneapolis - St. Paul Intl.
JAX
Jacksonville Intl.
$409 Roundtrip, found 3 days ago
$409
Roundtrip
found 3 days ago
Select Delta flight, departing Mon, Jul 13 from Minneapolis - St. Paul Intl. to Jacksonville Intl., returning Mon, Jul 20, priced at $409 found 3 days ago
American Airlines
Tue, Jun 30 - Wed, Jul 15
MSP
Minneapolis - St. Paul Intl.
GNV
Gainesville Regional
$411 Roundtrip, found 1 day ago
$411
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Jun 30 from Minneapolis - St. Paul Intl. to Gainesville Regional, returning Wed, Jul 15, priced at $411 found 1 day ago
Delta
Tue, Jun 30 - Wed, Jul 15
MSP
Minneapolis - St. Paul Intl.
GNV
Gainesville Regional
$414 Roundtrip, found 1 day ago
$414
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Jun 30 from Minneapolis - St. Paul Intl. to Gainesville Regional, returning Wed, Jul 15, priced at $414 found 1 day ago
Delta
Tue, Aug 4 - Tue, Aug 11
MSP
Minneapolis - St. Paul Intl.
TLH
Tallahassee Intl.
$417 Roundtrip, found 15 hours ago
$417
Roundtrip
found 15 hours ago
Select Delta flight, departing Tue, Aug 4 from Minneapolis - St. Paul Intl. to Tallahassee Intl., returning Tue, Aug 11, priced at $417 found 15 hours ago
Delta
Mon, Jul 13 - Mon, Jul 20
MSP
Minneapolis - St. Paul Intl.
JAX
Jacksonville Intl.
$417 Roundtrip, found 3 days ago
$417
Roundtrip
found 3 days ago
Select Delta flight, departing Mon, Jul 13 from Minneapolis - St. Paul Intl. to Jacksonville Intl., returning Mon, Jul 20, priced at $417 found 3 days ago
Delta
Thu, Jul 9 - Thu, Jul 16
MSP
Minneapolis - St. Paul Intl.
JAX
Jacksonville Intl.
$418 Roundtrip, found 4 days ago
$418
Roundtrip
found 4 days ago
Select Delta flight, departing Thu, Jul 9 from Minneapolis - St. Paul Intl. to Jacksonville Intl., returning Thu, Jul 16, priced at $418 found 4 days ago
United
Mon, Jul 13 - Sun, Jul 19
MSP
Minneapolis - St. Paul Intl.
JAX
Jacksonville Intl.
$419 Roundtrip, found 4 days ago
$419
Roundtrip
found 4 days ago
Select United flight, departing Mon, Jul 13 from Minneapolis - St. Paul Intl. to Jacksonville Intl., returning Sun, Jul 19, priced at $419 found 4 days ago
American Airlines
Tue, Jun 9 - Tue, Jun 16
PHX
Sky Harbor Intl.
GNV
Gainesville Regional
$470 Roundtrip, found 1 day ago
$470
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Jun 9 from Sky Harbor Intl. to Gainesville Regional, returning Tue, Jun 16, priced at $470 found 1 day ago

Cheap Flights to O Brien

Fall in love at first flight with your vacation to O Brien by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to O Brien on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in O Brien, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to O Brien

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to O Brien with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the null airport.

What is the cheapest month to fly to O Brien?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to O Brien are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to O Brien?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to O Brien.

What airport is best to fly into O Brien?

When you’re planning your trip to O Brien, convenience is the name of the game. Luckily, O Brien Gainesville Regional Airport is nearby so you can deplane and get going on checking off everything on your O Brien must-do list.

How much are flights to O Brien?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to O Brien on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $237, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to O Brien?

The trick to saving a stack of cash on your flight to O Brien? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $237 right now, why wait?

O Brien Flight Information
Destination airport
Jacksonville Intl.
Destination airport IATA code
JAX
Roundtrip price
$237

Last Minute Hotel Deals in O Brien

La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City

2.5 out of 5
165NW CALI DRIVE Lake City FL
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,095 reviews)
Front desk staff were all amazing with excellent hospitality as well as kindness. Will definitely be staying here again for future trips.

Reviewed on May 14, 2026

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La Quinta Inn & Suite by Wyndham Lake City
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

3.5 out of 5
16367 NW 167TH BLVD Alachua FL
Book a stay at this business-friendly hotel in Alachua. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,003 reviews)
Clean room, new rooms

Reviewed on May 15, 2026

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Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Comfort Suites Lake City

Comfort Suites Lake City

2.5 out of 5
3690 W Us Highway 90 Lake City FL
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,000 reviews)
No beach access. Front of hotel under construction- you have to go thru a small plywood area to get inside. No parking and the hotel smells like mold. Nothing like the pictures online. Avoid at all costs. Are son’s asthma is acting up because of how bad the hotel is. So upset that Expedia had this ...

Reviewed on May 9, 2026

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Comfort Suites Lake City
Americas Best Value Inn Lake City

Americas Best Value Inn Lake City

2 out of 5
3835 West US Highway 90 Lake City FL
Stay at this motel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8.6/10 Excellent! (1,001 reviews)
AC works. No usb ports, shower smaller than in my rv (and that is REALLY small). Breakfast was a muffin in a paper bag and a banana. If other people had been honest on their review we would never have stayed here. Hotel was really run down motel when you park in front of your door.

Reviewed on May 15, 2026

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Americas Best Value Inn Lake City
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

2 out of 5
1699 NE Co Rd 337 High Springs FL
Stay at this cabin in High Springs. Enjoy free parking, patios, and climate control. Popular attractions Ginnie Spring and Ruth B. Kirby Gilchrist Blue Springs ...
10/10 Exceptional! (211 reviews)
Just perfect

Reviewed on May 13, 2026

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Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center

2 out of 5
3340 W US Highway 90 Lake City FL
Stay at this motel in Lake City. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Regal UA Cinema 90 and Lake City Mall are located ...
7.8/10 Good! (171 reviews)
The staff is always very accommodating, I accidentally unplugged the cable to the tv so I couldn't watch TV, i went up to the desk and she called for help and he beat me to my room and fixed it immediately, of course I had no idea I unplugged it. They are always helpful and best of all leave me alone, ...

Reviewed on May 13, 2026

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Motel 6 – Lake City, Fl – Medical Center
Best Western Plus Lake City

Best Western Plus Lake City

2.5 out of 5
350 SW Florida Gateway Dr Lake City FL
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,065 reviews)
Great coffee machine and breakfast 😋 convenient.

Reviewed on May 14, 2026

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Best Western Plus Lake City
Courtyard By Marriott Lake City

Courtyard By Marriott Lake City

3 out of 5
3004 West US HWY 90 Lake City FL
Book a stay at this business-friendly hotel in Lake City. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Regal UA Cinema 90 and ...
9.4/10 Exceptional! (254 reviews)
This hostel was so nice and clean! It’s close to the highway and a lot of restaurants!! If you need somewhere to stay I highly recommend!

Reviewed on May 16, 2026

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Courtyard By Marriott Lake City
See all 377 properties in O Brien
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.