Search Cheap Flights to
O Brien

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O Brien Flights as Low as $199

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Delta
Tue, Jun 10 - Tue, Jun 17
ATL
Hartsfield-Jackson Atlanta Intl.
GNV
Gainesville Regional
$199 Roundtrip, found 5 days ago
$199
Roundtrip
found 5 days ago
Select Delta flight, departing Tue, Jun 10 from Hartsfield-Jackson Atlanta Intl. to Gainesville Regional, returning Tue, Jun 17, priced at $199 found 5 days ago
Delta
Sun, Jun 8 - Tue, Jun 17
ATL
Hartsfield-Jackson Atlanta Intl.
GNV
Gainesville Regional
$201 Roundtrip, found 5 days ago
$201
Roundtrip
found 5 days ago
Select Delta flight, departing Sun, Jun 8 from Hartsfield-Jackson Atlanta Intl. to Gainesville Regional, returning Tue, Jun 17, priced at $201 found 5 days ago
Frontier Airlines
Thu, Apr 24 - Fri, Apr 25
CLT
Charlotte-Douglas Intl.
JAX
Jacksonville Intl.
$213 Roundtrip, found 11 hours ago
$213
Roundtrip
found 11 hours ago
Select Frontier Airlines flight, departing Thu, Apr 24 from Charlotte-Douglas Intl. to Jacksonville Intl., returning Fri, Apr 25, priced at $213 found 11 hours ago
Delta
Tue, Jun 10 - Sat, Jun 14
ATL
Hartsfield-Jackson Atlanta Intl.
GNV
Gainesville Regional
$219 Roundtrip, found 5 days ago
$219
Roundtrip
found 5 days ago
Select Delta flight, departing Tue, Jun 10 from Hartsfield-Jackson Atlanta Intl. to Gainesville Regional, returning Sat, Jun 14, priced at $219 found 5 days ago
Delta
Sun, Jun 8 - Sat, Jun 14
ATL
Hartsfield-Jackson Atlanta Intl.
GNV
Gainesville Regional
$221 Roundtrip, found 5 days ago
$221
Roundtrip
found 5 days ago
Select Delta flight, departing Sun, Jun 8 from Hartsfield-Jackson Atlanta Intl. to Gainesville Regional, returning Sat, Jun 14, priced at $221 found 5 days ago
Frontier Airlines
Fri, Apr 18 - Mon, Apr 21
CLT
Charlotte-Douglas Intl.
JAX
Jacksonville Intl.
$222 Roundtrip, found 5 days ago
$222
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Fri, Apr 18 from Charlotte-Douglas Intl. to Jacksonville Intl., returning Mon, Apr 21, priced at $222 found 5 days ago
Delta
Sat, May 3 - Mon, May 12
ATL
Hartsfield-Jackson Atlanta Intl.
JAX
Jacksonville Intl.
$223 Roundtrip, found 2 days ago
$223
Roundtrip
found 2 days ago
Select Delta flight, departing Sat, May 3 from Hartsfield-Jackson Atlanta Intl. to Jacksonville Intl., returning Mon, May 12, priced at $223 found 2 days ago
Frontier Airlines
Thu, Apr 24 - Sun, Apr 27
CLT
Charlotte-Douglas Intl.
JAX
Jacksonville Intl.
$223 Roundtrip, found 11 hours ago
$223
Roundtrip
found 11 hours ago
Select Frontier Airlines flight, departing Thu, Apr 24 from Charlotte-Douglas Intl. to Jacksonville Intl., returning Sun, Apr 27, priced at $223 found 11 hours ago
Delta
Thu, Jun 12 - Sat, Jun 14
ATL
Hartsfield-Jackson Atlanta Intl.
GNV
Gainesville Regional
$241 Roundtrip, found 5 days ago
$241
Roundtrip
found 5 days ago
Select Delta flight, departing Thu, Jun 12 from Hartsfield-Jackson Atlanta Intl. to Gainesville Regional, returning Sat, Jun 14, priced at $241 found 5 days ago
American Airlines
Wed, Jun 11 - Sun, Jun 15
ATL
Hartsfield-Jackson Atlanta Intl.
GNV
Gainesville Regional
$255 Roundtrip, found 5 days ago
$255
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Jun 11 from Hartsfield-Jackson Atlanta Intl. to Gainesville Regional, returning Sun, Jun 15, priced at $255 found 5 days ago
Bargain Flight
Sat, May 17 - Sat, May 31
CLT
Charlotte-Douglas Intl.
JAX
Jacksonville Intl.
$309 Roundtrip, found 3 days ago
$309
Roundtrip
found 3 days ago
Select Bargain Flight flight, departing Sat, May 17 from Charlotte-Douglas Intl. to Jacksonville Intl., returning Sat, May 31, priced at $309 found 3 days ago
Delta
Mon, May 5 - Sat, May 10
ATL
Hartsfield-Jackson Atlanta Intl.
TLH
Tallahassee Intl.
$325 Roundtrip, found 21 hours ago
$325
Roundtrip
found 21 hours ago
Select Delta flight, departing Mon, May 5 from Hartsfield-Jackson Atlanta Intl. to Tallahassee Intl., returning Sat, May 10, priced at $325 found 21 hours ago
Delta
Thu, Apr 17 - Thu, Apr 24
ATL
Hartsfield-Jackson Atlanta Intl.
VLD
Valdosta Regional
$368 Roundtrip, found 4 days ago
$368
Roundtrip
found 4 days ago
Select Delta flight, departing Thu, Apr 17 from Hartsfield-Jackson Atlanta Intl. to Valdosta Regional, returning Thu, Apr 24, priced at $368 found 4 days ago
JetBlue Airways
Mon, May 5 - Tue, May 6
ATL
Hartsfield-Jackson Atlanta Intl.
JAX
Jacksonville Intl.
$410 Roundtrip, found 2 days ago
$410
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Mon, May 5 from Hartsfield-Jackson Atlanta Intl. to Jacksonville Intl., returning Tue, May 6, priced at $410 found 2 days ago
American Airlines
Wed, Apr 16 - Tue, Apr 22
CLT
Charlotte-Douglas Intl.
TLH
Tallahassee Intl.
$435 Roundtrip, found 1 day ago
$435
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Apr 16 from Charlotte-Douglas Intl. to Tallahassee Intl., returning Tue, Apr 22, priced at $435 found 1 day ago
American Airlines
Mon, Apr 28 - Mon, May 19
ACY
Atlantic City Intl.
TLH
Tallahassee Intl.
$493 Roundtrip, found 23 hours ago
$493
Roundtrip
found 23 hours ago
Select American Airlines flight, departing Mon, Apr 28 from Atlantic City Intl. to Tallahassee Intl., returning Mon, May 19, priced at $493 found 23 hours ago

Cheap Flights to O Brien

Fall in love at first flight with your vacation to O Brien by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to O Brien on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in O Brien, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to O Brien

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to O Brien with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the null airport.

What is the cheapest month to fly to O Brien?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to O Brien are in June, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to O Brien?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to O Brien.

What airport is best to fly into O Brien?

When you’re planning your trip to O Brien, convenience is the name of the game. Luckily, O Brien Gainesville Regional Airport is nearby so you can deplane and get going on checking off everything on your O Brien must-do list.

How much are flights to O Brien?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to O Brien on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $199, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to O Brien?

The trick to saving a stack of cash on your flight to O Brien? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $199 right now, why wait?

O Brien Flight Information
Destination airport
Gainesville Regional
Destination airport IATA code
GNV
Roundtrip price
$199

Last Minute Hotel Deals in O Brien

La Quinta Inn & Suite by Wyndham Lake City
La Quinta Inn & Suite by Wyndham Lake City
2.5 out of 5
165NW CALI DRIVE, Lake City, FL
The price is $113 per night from Apr 20 to Apr 21
$113
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,002 reviews)
"Enjoyed the stay"

Reviewed on Apr 11, 2025

La Quinta Inn & Suite by Wyndham Lake City
Courtyard By Marriott Lake City
Courtyard By Marriott Lake City
3 out of 5
3004 West US HWY 90, Lake City, FL
The price is $118 per night from Apr 27 to Apr 28
$118
includes taxes & fees
Apr 27 - Apr 28
Stay at this 3-star business-friendly hotel in Lake City. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Lake City Mall and Southside ...
9.6/10 Exceptional! (64 reviews)
"Upset that when I reserved 2 rooms it did not save two rooms. Only one room. I reserved one time both rooms but yet only one showed. That needs to fixed. They found it 2 hours later under a different name."

Reviewed on Apr 13, 2025

Courtyard By Marriott Lake City
Days Inn by Wyndham Lake City I-75
Days Inn by Wyndham Lake City I-75
2 out of 5
3144 West US Highway 90, Lake City, FL
The price is $76 per night from Apr 20 to Apr 21
$76
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free parking, and WiFi (surcharge). Our guests praise the helpful staff and the ...
7.2/10 Good! (1,003 reviews)
"La habitación estuvo amplia y limpia, tenía todas las facilidades que uno puede necesitar; las camas y el bedding cómodos. El desayuno estuvo muy simple"

Reviewed on Apr 5, 2025

Days Inn by Wyndham Lake City I-75
Best Western Plus Lake City
Best Western Plus Lake City
2.5 out of 5
350 SW Florida Gateway Dr, Lake City, FL
The price is $141 per night from May 12 to May 13
$141
includes taxes & fees
May 12 - May 13
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,003 reviews)
"Breakfast outstanding"

Reviewed on Apr 13, 2025

Best Western Plus Lake City
TownePlace Suites by Marriott Lake City
TownePlace Suites by Marriott Lake City
3 out of 5
178 NW COMMERCE DR, Lake City, FL
The price is $145 per night from Apr 16 to Apr 17
$145
includes taxes & fees
Apr 16 - Apr 17
Stay at this 3-star business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Lake City Mall and Southside ...
9.8/10 Exceptional! (46 reviews)
"Cute modern decor, excellent room & property amenities, conveniently located, pet friendly, great staff. Overall high quality property for business or leisure."

Reviewed on Apr 6, 2025

TownePlace Suites by Marriott Lake City
Americas Best Value Inn Lake City
Americas Best Value Inn Lake City
2 out of 5
3835 West US Highway 90, Lake City, FL
The price is $85 per night from Apr 16 to Apr 17
$85
includes taxes & fees
Apr 16 - Apr 17
Stay at this motel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8.6/10 Excellent! (1,000 reviews)
"Room was clean and be comfy. Staff very friendly and helpful"

Reviewed on Apr 8, 2025

Americas Best Value Inn Lake City
Comfort Suites Lake City
Comfort Suites Lake City
2.5 out of 5
3690 W Us Highway 90, Lake City, FL
The price is $128 per night from Apr 16 to Apr 17
$128
includes taxes & fees
Apr 16 - Apr 17
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,002 reviews)
"A road trip overnight stay. Staff was friendly, hotel clean. We actually overslept as we were comfortable. Ordered delivery from Cracker Barrel for dinner. Perfect for our needs."

Reviewed on Apr 12, 2025

Comfort Suites Lake City
Holiday Inn Express Hotel & Suites LIVE OAK by IHG
Holiday Inn Express Hotel & Suites LIVE OAK by IHG
2.5 out of 5
6694 Us Highway 129, Live Oak, FL
The price is $122 per night from Apr 27 to Apr 28
$122
includes taxes & fees
Apr 27 - Apr 28
Book a stay at this business-friendly hotel in Live Oak. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (678 reviews)
"This was a last minute booking, the staff was very accommodating. Thank you"

Reviewed on Mar 18, 2025

Holiday Inn Express Hotel & Suites LIVE OAK by IHG
See all 311 properties in O Brien
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.