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O Brien

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O Brien Flights as Low as $112

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Breeze Airways
Tue, Sep 8 - Tue, Sep 15
FLL
Fort Lauderdale - Hollywood Intl.
TLH
Tallahassee Intl.
$112 Roundtrip, found 6 days ago
$112
Roundtrip
found 6 days ago
Select Breeze Airways flight, departing Tue, Sep 8 from Fort Lauderdale - Hollywood Intl. to Tallahassee Intl., returning Tue, Sep 15, priced at $112 found 6 days ago
Breeze Airways
Tue, Sep 8 - Tue, Sep 15
FLL
Fort Lauderdale - Hollywood Intl.
TLH
Tallahassee Intl.
$117 Roundtrip, found 6 days ago
$117
Roundtrip
found 6 days ago
Select Breeze Airways flight, departing Tue, Sep 8 from Fort Lauderdale - Hollywood Intl. to Tallahassee Intl., returning Tue, Sep 15, priced at $117 found 6 days ago
Breeze Airways
Tue, Sep 8 - Tue, Sep 15
FLL
Fort Lauderdale - Hollywood Intl.
TLH
Tallahassee Intl.
$122 Roundtrip, found 6 days ago
$122
Roundtrip
found 6 days ago
Select Breeze Airways flight, departing Tue, Sep 8 from Fort Lauderdale - Hollywood Intl. to Tallahassee Intl., returning Tue, Sep 15, priced at $122 found 6 days ago
Breeze Airways
Sun, Sep 6 - Thu, Sep 17
FLL
Fort Lauderdale - Hollywood Intl.
TLH
Tallahassee Intl.
$132 Roundtrip, found 1 day ago
$132
Roundtrip
found 1 day ago
Select Breeze Airways flight, departing Sun, Sep 6 from Fort Lauderdale - Hollywood Intl. to Tallahassee Intl., returning Thu, Sep 17, priced at $132 found 1 day ago
Breeze Airways
Fri, Jul 3 - Sun, Jul 5
FLL
Fort Lauderdale - Hollywood Intl.
JAX
Jacksonville Intl.
$135 Roundtrip, found 6 days ago
$135
Roundtrip
found 6 days ago
Select Breeze Airways flight, departing Fri, Jul 3 from Fort Lauderdale - Hollywood Intl. to Jacksonville Intl., returning Sun, Jul 5, priced at $135 found 6 days ago
Breeze Airways
Sun, Sep 6 - Thu, Sep 17
FLL
Fort Lauderdale - Hollywood Intl.
TLH
Tallahassee Intl.
$137 Roundtrip, found 1 day ago
$137
Roundtrip
found 1 day ago
Select Breeze Airways flight, departing Sun, Sep 6 from Fort Lauderdale - Hollywood Intl. to Tallahassee Intl., returning Thu, Sep 17, priced at $137 found 1 day ago
Breeze Airways
Fri, Jul 3 - Sun, Jul 5
FLL
Fort Lauderdale - Hollywood Intl.
JAX
Jacksonville Intl.
$140 Roundtrip, found 6 days ago
$140
Roundtrip
found 6 days ago
Select Breeze Airways flight, departing Fri, Jul 3 from Fort Lauderdale - Hollywood Intl. to Jacksonville Intl., returning Sun, Jul 5, priced at $140 found 6 days ago
Breeze Airways
Sun, Sep 6 - Thu, Sep 17
FLL
Fort Lauderdale - Hollywood Intl.
TLH
Tallahassee Intl.
$142 Roundtrip, found 1 day ago
$142
Roundtrip
found 1 day ago
Select Breeze Airways flight, departing Sun, Sep 6 from Fort Lauderdale - Hollywood Intl. to Tallahassee Intl., returning Thu, Sep 17, priced at $142 found 1 day ago
Breeze Airways
Fri, Jul 3 - Sun, Jul 5
FLL
Fort Lauderdale - Hollywood Intl.
JAX
Jacksonville Intl.
$145 Roundtrip, found 6 days ago
$145
Roundtrip
found 6 days ago
Select Breeze Airways flight, departing Fri, Jul 3 from Fort Lauderdale - Hollywood Intl. to Jacksonville Intl., returning Sun, Jul 5, priced at $145 found 6 days ago
JetBlue Airways
Fri, Jul 3 - Sun, Jul 5
FLL
Fort Lauderdale - Hollywood Intl.
JAX
Jacksonville Intl.
$233 Roundtrip, found 6 days ago
$233
Roundtrip
found 6 days ago
Select JetBlue Airways flight, departing Fri, Jul 3 from Fort Lauderdale - Hollywood Intl. to Jacksonville Intl., returning Sun, Jul 5, priced at $233 found 6 days ago
Delta
Tue, Sep 8 - Tue, Sep 15
FLL
Fort Lauderdale - Hollywood Intl.
TLH
Tallahassee Intl.
$261 Roundtrip, found 6 days ago
$261
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Sep 8 from Fort Lauderdale - Hollywood Intl. to Tallahassee Intl., returning Tue, Sep 15, priced at $261 found 6 days ago
Frontier Airlines
Fri, Jul 3 - Sun, Jul 5
FLL
Fort Lauderdale - Hollywood Intl.
JAX
Jacksonville Intl.
$297 Roundtrip, found 6 days ago
$297
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Fri, Jul 3 from Fort Lauderdale - Hollywood Intl. to Jacksonville Intl., returning Sun, Jul 5, priced at $297 found 6 days ago
American Airlines
Fri, Jul 3 - Sun, Jul 5
FLL
Fort Lauderdale - Hollywood Intl.
JAX
Jacksonville Intl.
$387 Roundtrip, found 6 days ago
$387
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Jul 3 from Fort Lauderdale - Hollywood Intl. to Jacksonville Intl., returning Sun, Jul 5, priced at $387 found 6 days ago
American Airlines
Sun, Jun 7 - Sat, Jun 13
MIA
Miami Intl.
TLH
Tallahassee Intl.
$588 Roundtrip, found 1 day ago
$588
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sun, Jun 7 from Miami Intl. to Tallahassee Intl., returning Sat, Jun 13, priced at $588 found 1 day ago
American Airlines
Thu, Jul 30 - Sun, Aug 9
STT
Cyril E. King
TLH
Tallahassee Intl.
$696 Roundtrip, found 12 hours ago
$696
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Thu, Jul 30 from Cyril E. King to Tallahassee Intl., returning Sun, Aug 9, priced at $696 found 12 hours ago
United
Fri, Jul 3 - Sun, Jul 5
FLL
Fort Lauderdale - Hollywood Intl.
JAX
Jacksonville Intl.
$1,063 Roundtrip, found 6 days ago
$1,063
Roundtrip
found 6 days ago
Select United flight, departing Fri, Jul 3 from Fort Lauderdale - Hollywood Intl. to Jacksonville Intl., returning Sun, Jul 5, priced at $1,063 found 6 days ago

Cheap Flights to O Brien

Fall in love at first flight with your vacation to O Brien by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to O Brien on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in O Brien, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to O Brien

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to O Brien with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the null airport.

What is the cheapest month to fly to O Brien?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to O Brien are in September, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to O Brien?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to O Brien.

What airport is best to fly into O Brien?

When you’re planning your trip to O Brien, convenience is the name of the game. Luckily, O Brien Gainesville Regional Airport is nearby so you can deplane and get going on checking off everything on your O Brien must-do list.

How much are flights to O Brien?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to O Brien on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $112, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to O Brien?

The trick to saving a stack of cash on your flight to O Brien? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $112 right now, why wait?

O Brien Flight Information
Destination airport
Jacksonville Intl.
Destination airport IATA code
JAX
Roundtrip price
$280

Last Minute Hotel Deals in O Brien

La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City

2.5 out of 5
165NW CALI DRIVE Lake City FL
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,115 reviews)
"The hotel is showing its age and in the bathroom of our room #216 someone used white caulk all over the beige tile to seal it instead of replacing the grout. Looked very unprofessionally done and ghetto. Otherwise it was a great hotel stay and the staff was friendly."

Reviewed on Jun 3, 2026

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La Quinta Inn & Suite by Wyndham Lake City
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

3.5 out of 5
16367 NW 167TH BLVD Alachua FL
Book a stay at this business-friendly hotel in Alachua. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,007 reviews)
"Good place."

Reviewed on Jun 2, 2026

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Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

2 out of 5
1699 NE Co Rd 337 High Springs FL
Stay at this cabin in High Springs. Enjoy free parking, patios, and climate control. Popular attractions Ginnie Spring and Ruth B. Kirby Gilchrist Blue Springs ...
10/10 Exceptional! (223 reviews)
"Amazing spot to be out of the world."

Reviewed on Jun 3, 2026

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Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
Comfort Suites Lake City

Comfort Suites Lake City

2.5 out of 5
3690 W Us Highway 90 Lake City FL
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,012 reviews)
"Rooms were clean. Property was kept up. Only reason I gave it a low rating was the location of the room. We were next to an exit door and it was very loud"

Reviewed on Jun 5, 2026

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Comfort Suites Lake City
Baymont by Wyndham Lake City I-75

Baymont by Wyndham Lake City I-75

2.5 out of 5
3598 W Us Highway 90 Lake City FL
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
5/10 (1,001 reviews)
"Desk & housekeeping staff were super helpful & friendly!"

Reviewed on Jun 2, 2026

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Baymont by Wyndham Lake City I-75
Best Western Plus Lake City

Best Western Plus Lake City

2.5 out of 5
350 SW Florida Gateway Dr Lake City FL
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,066 reviews)
"This was a quick overnight with quick access to I75. The grounds were clean, there was a nice sitting area outside. The room was clean and what I expected. The bed was comfortable and the pillows were soft just like I like. The breakfast was above average, with the waffle maker and eggs and bacon. ..."

Reviewed on Jun 5, 2026

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Best Western Plus Lake City
Tru by Hilton Lake City

Tru by Hilton Lake City

2.5 out of 5
284 NW Centurion Court Lake City FL
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,011 reviews)
"Excellent value. Helpful staff, easy check in, noon check out. Highly recommend."

Reviewed on Jun 3, 2026

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Tru by Hilton Lake City
Days Inn by Wyndham Lake City I-10

Days Inn by Wyndham Lake City I-10

2 out of 5
3430 N Us Highway 441 Lake City FL
Book a stay at this business-friendly motel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (1,003 reviews)
"Was ok"

Reviewed on Jun 2, 2026

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Days Inn by Wyndham Lake City I-10
See all 375 properties in O Brien
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.