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Hotels in O Brien

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Choose from 320 O Brien Hotel Deals

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

3.5 out of 5
16367 NW 167TH BLVD, Alachua, FL
  • 27 min drive from Ichetucknee Springs State Park
Stay at this 3.5-star business-friendly hotel in Alachua. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City

2.5 out of 5
450 SW Florida Gateway Drive, Lake City, FL
  • 35 min drive from Ichetucknee Springs State Park
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Hampton Inn & Suites Lake City
Tru by Hilton Lake City

Tru by Hilton Lake City

2.5 out of 5
284 NW Centurion Court, Lake City, FL
  • 36 min drive from Ichetucknee Springs State Park
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Tru by Hilton Lake City
Postcard Cabins Gilchrist Springs

Postcard Cabins Gilchrist Springs

2 out of 5
1699 NE Co Rd 337, High Springs, FL
  • 34 min drive from Ichetucknee Springs State Park
Stay at this cabin in High Springs. Enjoy free parking, patios, and climate control. Popular attractions Ginnie Spring and Ruth B. Kirby Gilchrist Blue Springs ...
Postcard Cabins Gilchrist Springs
La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City

2.5 out of 5
165NW CALI DRIVE, Lake City, FL
  • 36 min drive from Ichetucknee Springs State Park
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
La Quinta Inn & Suite by Wyndham Lake City
Best Western Plus Lake City

Best Western Plus Lake City

2.5 out of 5
350 SW Florida Gateway Dr, Lake City, FL
  • 35 min drive from Ichetucknee Springs State Park
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Best Western Plus Lake City
Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75

2.5 out of 5
15930 Northwest 163rd Lane, Alachua, FL
  • 27 min drive from Ichetucknee Springs State Park
Book a stay at this business-friendly hotel in Alachua. Enjoy free parking, a fitness center, and a 24-hour front desk. Our guests praise the helpful staff and ...
Hampton Inn & Suites Alachua I-75
Holiday Inn & Suites Lake City by IHG

Holiday Inn & Suites Lake City by IHG

3 out of 5
213 Sw Commerce Dr, Lake City, FL
  • 35 min drive from Ichetucknee Springs State Park
Stay at this 3-star business-friendly hotel in Lake City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
Holiday Inn & Suites Lake City by IHG
Comfort Suites Lake City

Comfort Suites Lake City

2.5 out of 5
3690 W Us Highway 90, Lake City, FL
  • 36 min drive from Ichetucknee Springs State Park
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Comfort Suites Lake City
Courtyard By Marriott Lake City

Courtyard By Marriott Lake City

3 out of 5
3004 West US HWY 90, Lake City, FL
  • 35 min drive from Ichetucknee Springs State Park
Stay at this 3-star business-friendly hotel in Lake City. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Regal UA Cinema 90 and ...
Courtyard By Marriott Lake City
Americas Best Value Inn Alachua

Americas Best Value Inn Alachua

2 out of 5
16100 NW US Highway 441, Alachua, FL
  • 28 min drive from Ichetucknee Springs State Park
Stay at this motel in Alachua. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Alachua Sports Complex and City of Alachua Recreation ...
Americas Best Value Inn Alachua
Baymont by Wyndham Lake City

Baymont by Wyndham Lake City

2.5 out of 5
3598 W Us Highway 90, Lake City, FL
  • 36 min drive from Ichetucknee Springs State Park
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Baymont by Wyndham Lake City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in O Brien

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in O Brien.

Choosing the right hotel in Florida has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of O Brien’s 320 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $65. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great O Brien hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in O Brien. No matter your reason for visiting O Brien, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About O Brien hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in O Brien for as low as $65.

How many hotels are there in O Brien?

With over 320 hotels in O Brien, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $65.

How to find cheap car rentals in O Brien?

Finding a cheap car rental deal in O Brien is as easy as scoring cheap hotels in O Brien. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.