Search Cheap Flights to
Pontotoc

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Pontotoc Flights as Low as $359

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

United
Tue, Jun 23 - Tue, Jun 30
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$359 Roundtrip, found 4 days ago
$359
Roundtrip
found 4 days ago
Select United flight, departing Tue, Jun 23 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Tue, Jun 30, priced at $359 found 4 days ago
American Airlines
Tue, Jun 23 - Tue, Jun 30
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$400 Roundtrip, found 6 days ago
$400
Roundtrip
found 6 days ago
Select American Airlines flight, departing Tue, Jun 23 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Tue, Jun 30, priced at $400 found 6 days ago
United
Tue, Jun 23 - Tue, Jun 30
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$429 Roundtrip, found 4 days ago
$429
Roundtrip
found 4 days ago
Select United flight, departing Tue, Jun 23 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Tue, Jun 30, priced at $429 found 4 days ago
American Airlines
Tue, Jun 23 - Wed, Jul 1
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$434 Roundtrip, found 2 days ago
$434
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Jun 23 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Wed, Jul 1, priced at $434 found 2 days ago
American Airlines
Wed, Jun 24 - Tue, Jun 30
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$441 Roundtrip, found 8 hours ago
$441
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Wed, Jun 24 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Tue, Jun 30, priced at $441 found 8 hours ago
American Airlines
Tue, Jun 23 - Tue, Jun 30
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$444 Roundtrip, found 4 days ago
$444
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Jun 23 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Tue, Jun 30, priced at $444 found 4 days ago
United
Tue, Jun 23 - Tue, Jun 30
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$458 Roundtrip, found 6 days ago
$458
Roundtrip
found 6 days ago
Select United flight, departing Tue, Jun 23 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Tue, Jun 30, priced at $458 found 6 days ago
American Airlines
Wed, Jun 24 - Tue, Jun 30
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$463 Roundtrip, found 8 hours ago
$463
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Wed, Jun 24 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Tue, Jun 30, priced at $463 found 8 hours ago
United
Tue, Jun 23 - Tue, Jun 30
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$464 Roundtrip, found 4 days ago
$464
Roundtrip
found 4 days ago
Select United flight, departing Tue, Jun 23 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Tue, Jun 30, priced at $464 found 4 days ago
United
Tue, Jun 23 - Tue, Jun 30
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$468 Roundtrip, found 5 days ago
$468
Roundtrip
found 5 days ago
Select United flight, departing Tue, Jun 23 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Tue, Jun 30, priced at $468 found 5 days ago
American Airlines
Tue, Jun 23 - Wed, Jul 1
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$473 Roundtrip, found 2 days ago
$473
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Jun 23 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Wed, Jul 1, priced at $473 found 2 days ago
United
Tue, Jun 23 - Tue, Jun 30
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$473 Roundtrip, found 4 days ago
$473
Roundtrip
found 4 days ago
Select United flight, departing Tue, Jun 23 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Tue, Jun 30, priced at $473 found 4 days ago
American Airlines
Tue, Jun 23 - Wed, Jul 1
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$486 Roundtrip, found 2 days ago
$486
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Jun 23 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Wed, Jul 1, priced at $486 found 2 days ago
American Airlines
Wed, Jun 24 - Tue, Jun 30
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$493 Roundtrip, found 8 hours ago
$493
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Wed, Jun 24 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Tue, Jun 30, priced at $493 found 8 hours ago
American Airlines
Tue, Jun 23 - Tue, Jun 30
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$496 Roundtrip, found 4 days ago
$496
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Jun 23 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Tue, Jun 30, priced at $496 found 4 days ago
United
Wed, Jun 24 - Tue, Jun 30
DTW
Detroit Metropolitan Wayne County
TUP
Tupelo Regional
$498 Roundtrip, found 8 hours ago
$498
Roundtrip
found 8 hours ago
Select United flight, departing Wed, Jun 24 from Detroit Metropolitan Wayne County to Tupelo Regional, returning Tue, Jun 30, priced at $498 found 8 hours ago

Cheap Flights to Pontotoc

Fall in love at first flight with your vacation to Pontotoc by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Pontotoc on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Pontotoc, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Pontotoc

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Pontotoc with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the TUP airport.

What is the cheapest month to fly to Pontotoc?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Pontotoc are in June, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Pontotoc?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Pontotoc.

What airport is best to fly into Pontotoc?

When you’re planning your trip to Pontotoc, convenience is the name of the game. Luckily, Pontotoc Tupelo Regional Airport is nearby so you can deplane and get going on checking off everything on your Pontotoc must-do list.

How much are flights to Pontotoc?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Pontotoc on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $359, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Pontotoc?

The trick to saving a stack of cash on your flight to Pontotoc? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $359 right now, why wait?

Pontotoc Flight Information
Destination airport
Tupelo Regional
Destination airport IATA code
TUP
Roundtrip price
$359

Last Minute Hotel Deals in Pontotoc

American Inn - Pontotoc

American Inn - Pontotoc

2 out of 5
217 Highway 15 N Pontotoc MS
Stay at this hotel in Pontotoc. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the clean rooms in our reviews. Popular attraction ...
8/10 Very Good! (357 reviews)
"."

Reviewed on May 8, 2026

Get rates
American Inn - Pontotoc
Tru by Hilton Oxford

Tru by Hilton Oxford

2.5 out of 5
97 Ed Perry Blvd Oxford MS
Book a stay at this business-friendly hotel in Oxford. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (1,002 reviews)
"Very nice hotel! Shuttle to Ole Miss was perfect!"

Reviewed on Jun 2, 2026

Get rates
Tru by Hilton Oxford
La Quinta Inn & Suites by Wyndham Oxford

La Quinta Inn & Suites by Wyndham Oxford

3 out of 5
1171 Frontage Road Oxford MS
Book a stay at this business-friendly hotel in Oxford. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (1,005 reviews)
"Everything was great and staff was very friendly!"

Reviewed on Jun 2, 2026

Get rates
La Quinta Inn & Suites by Wyndham Oxford
The Inn at Ole Miss

The Inn at Ole Miss

3 out of 5
120 Alumni Drive University MS
Book a stay at this business-friendly hotel in University. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,002 reviews)
"Pros: Friendly staff Convenient location Clean and spacious Friendly shuttle to the Square Cons: Pillows are horribly fat and uncomfortable. McCormicks is terrible: understaffed and food is problematic. First visit on a previous visit my son and I both became ill. Another visit on this trip we ordered ..."

Reviewed on Jun 3, 2026

Get rates
The Inn at Ole Miss
Best Western Plus Tupelo Inn & Suites

Best Western Plus Tupelo Inn & Suites

2.5 out of 5
3158 N Gloster Street Tupelo MS
Book a stay at this business-friendly hotel in Tupelo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,011 reviews)
"The location was great and the staff was so friendly when we walked in. Room was clean and comfy."

Reviewed on Jun 2, 2026

Get rates
Best Western Plus Tupelo Inn & Suites
Graduate by Hilton Oxford

Graduate by Hilton Oxford

4 out of 5
400 North Lamar Boulevard Oxford MS
Book a stay at this business-friendly hotel in Oxford. Enjoy free WiFi, 2 restaurants, and a rooftop terrace. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (1,001 reviews)
"It was clean, close to the square. Staff was very helpful!"

Reviewed on May 31, 2026

Get rates
Graduate by Hilton Oxford
La Quinta Inn & Suites by Wyndham Tupelo

La Quinta Inn & Suites by Wyndham Tupelo

3 out of 5
1013 N Gloster St Tupelo MS
Book a stay at this business-friendly hotel in Tupelo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,011 reviews)
"Very clean and the staff were very friendly. Breakfast was the normal basics but everything was fresh."

Reviewed on Jun 3, 2026

Get rates
La Quinta Inn & Suites by Wyndham Tupelo
Red Roof Inn Tupelo

Red Roof Inn Tupelo

2 out of 5
1516 Mccullough Blvd Tupelo MS
Book a stay at this business-friendly hotel in Tupelo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.2/10 Very Good! (1,001 reviews)
"Parking was very secure. The area is far enough off the highway to be nice and quiet. The room was very clean and the bed comfortable. The staff is friendly and helpful."

Reviewed on Jun 2, 2026

Get rates
Red Roof Inn Tupelo
See all 971 properties in Pontotoc
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.