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Santa Isabel

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Santa Isabel Flights as Low as $152

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Spirit Airlines
Fri, May 9 - Sun, May 11
MCO
Orlando Intl.
SJU
Luis Munoz Marin Intl.
$152 Roundtrip, found 11 hours ago
$152
Roundtrip
found 11 hours ago
Select Spirit Airlines flight, departing Fri, May 9 from Orlando Intl. to Luis Munoz Marin Intl., returning Sun, May 11, priced at $152 found 11 hours ago
Frontier Airlines
Wed, May 14 - Fri, May 16
MCO
Orlando Intl.
SJU
Luis Munoz Marin Intl.
$155 Roundtrip, found 4 days ago
$155
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Wed, May 14 from Orlando Intl. to Luis Munoz Marin Intl., returning Fri, May 16, priced at $155 found 4 days ago
Spirit Airlines
Fri, May 9 - Fri, May 16
MCO
Orlando Intl.
SJU
Luis Munoz Marin Intl.
$160 Roundtrip, found 11 hours ago
$160
Roundtrip
found 11 hours ago
Select Spirit Airlines flight, departing Fri, May 9 from Orlando Intl. to Luis Munoz Marin Intl., returning Fri, May 16, priced at $160 found 11 hours ago
Spirit Airlines
Fri, May 9 - Thu, May 15
MCO
Orlando Intl.
SJU
Luis Munoz Marin Intl.
$166 Roundtrip, found 11 hours ago
$166
Roundtrip
found 11 hours ago
Select Spirit Airlines flight, departing Fri, May 9 from Orlando Intl. to Luis Munoz Marin Intl., returning Thu, May 15, priced at $166 found 11 hours ago
Frontier Airlines
Sun, May 4 - Sat, May 10
MCO
Orlando Intl.
SJU
Luis Munoz Marin Intl.
$170 Roundtrip, found 4 days ago
$170
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Sun, May 4 from Orlando Intl. to Luis Munoz Marin Intl., returning Sat, May 10, priced at $170 found 4 days ago
Frontier Airlines
Thu, May 1 - Fri, May 2
MCO
Orlando Intl.
PSE
Mercedita
$198 Roundtrip, found 1 day ago
$198
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, May 1 from Orlando Intl. to Mercedita, returning Fri, May 2, priced at $198 found 1 day ago
Frontier Airlines
Thu, Apr 24 - Fri, Apr 25
MCO
Orlando Intl.
BQN
Rafael Hernandez
$201 Roundtrip, found 2 days ago
$201
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Thu, Apr 24 from Orlando Intl. to Rafael Hernandez, returning Fri, Apr 25, priced at $201 found 2 days ago
Frontier Airlines
Wed, May 28 - Thu, May 29
CLE
Hopkins Intl.
SJU
Luis Munoz Marin Intl.
$203 Roundtrip, found 4 days ago
$203
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Wed, May 28 from Hopkins Intl. to Luis Munoz Marin Intl., returning Thu, May 29, priced at $203 found 4 days ago
Delta
Sun, Apr 27 - Fri, May 9
CLE
Hopkins Intl.
SJU
Luis Munoz Marin Intl.
$207 Roundtrip, found 6 days ago
$207
Roundtrip
found 6 days ago
Select Delta flight, departing Sun, Apr 27 from Hopkins Intl. to Luis Munoz Marin Intl., returning Fri, May 9, priced at $207 found 6 days ago
Spirit Airlines
Sat, May 10 - Sat, May 17
RIC
Richmond Intl.
SJU
Luis Munoz Marin Intl.
$232 Roundtrip, found 5 days ago
$232
Roundtrip
found 5 days ago
Select Spirit Airlines flight, departing Sat, May 10 from Richmond Intl. to Luis Munoz Marin Intl., returning Sat, May 17, priced at $232 found 5 days ago
JetBlue Airways
Mon, May 5 - Fri, May 9
MCO
Orlando Intl.
BQN
Rafael Hernandez
$246 Roundtrip, found 1 day ago
$246
Roundtrip
found 1 day ago
Select JetBlue Airways flight, departing Mon, May 5 from Orlando Intl. to Rafael Hernandez, returning Fri, May 9, priced at $246 found 1 day ago
United
Tue, May 6 - Sat, May 10
GRR
Gerald R. Ford Intl.
SJU
Luis Munoz Marin Intl.
$257 Roundtrip, found 15 hours ago
$257
Roundtrip
found 15 hours ago
Select United flight, departing Tue, May 6 from Gerald R. Ford Intl. to Luis Munoz Marin Intl., returning Sat, May 10, priced at $257 found 15 hours ago
American Airlines
Wed, Nov 19 - Wed, Dec 3
MCO
Orlando Intl.
SJU
Luis Munoz Marin Intl.
$273 Roundtrip, found 5 days ago
$273
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Nov 19 from Orlando Intl. to Luis Munoz Marin Intl., returning Wed, Dec 3, priced at $273 found 5 days ago
JetBlue Airways
Sat, May 3 - Sat, May 10
RIC
Richmond Intl.
PSE
Mercedita
$314 Roundtrip, found 4 days ago
$314
Roundtrip
found 4 days ago
Select JetBlue Airways flight, departing Sat, May 3 from Richmond Intl. to Mercedita, returning Sat, May 10, priced at $314 found 4 days ago
Frontier Airlines
Fri, Apr 25 - Sun, May 4
GRR
Gerald R. Ford Intl.
PSE
Mercedita
$327 Roundtrip, found 17 hours ago
$327
Roundtrip
found 17 hours ago
Select Frontier Airlines flight, departing Fri, Apr 25 from Gerald R. Ford Intl. to Mercedita, returning Sun, May 4, priced at $327 found 17 hours ago
JetBlue Airways
Wed, Dec 24 - Fri, Jan 9
CLE
Hopkins Intl.
PSE
Mercedita
$961 Roundtrip, found 20 hours ago
$961
Roundtrip
found 20 hours ago
Select JetBlue Airways flight, departing Wed, Dec 24 from Hopkins Intl. to Mercedita, returning Fri, Jan 9, priced at $961 found 20 hours ago

Cheap Flights to Santa Isabel

Fall in love at first flight with your vacation to Santa Isabel by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santa Isabel on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santa Isabel, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santa Isabel

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santa Isabel with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the SJU airport.

What is the cheapest month to fly to Santa Isabel?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santa Isabel are in May, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santa Isabel?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santa Isabel.

What airport is best to fly into Santa Isabel?

When you’re planning your trip to Santa Isabel, convenience is the name of the game. Luckily, Santa Isabel Mercedita Airport is nearby so you can deplane and get going on checking off everything on your Santa Isabel must-do list.

How much are flights to Santa Isabel?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santa Isabel on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $152, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santa Isabel?

The trick to saving a stack of cash on your flight to Santa Isabel? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $152 right now, why wait?

Santa Isabel Flight Information
Destination airport
Luis Munoz Marin Intl.
Destination airport IATA code
SJU
Roundtrip price
$152

Last Minute Hotel Deals in Santa Isabel

Hotel Las Vegas
Hotel Las Vegas
3 out of 5
PR 153, Km 2.9, Santa Isabel
The price is $90 per night from Apr 17 to Apr 18
$90
includes taxes & fees
Apr 17 - Apr 18
Stay at this 3-star motel in Santa Isabel. Enjoy 24-hour room service, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and ...
7.8/10 Good! (259 reviews)
"The employees bro, really friendly and the property manager awesome"

Reviewed on Apr 4, 2025

Hotel Las Vegas
Hacienda del Sur
Hacienda del Sur
2 out of 5
Carr 545 KM 1.5, Sector Gabia, Santa Isabel
The price is $222 per night from May 15 to May 16
$222
includes taxes & fees
May 15 - May 16
Stay at this hotel in Santa Isabel. Enjoy free WiFi, free parking, and cable TV channels. Popular attractions Coamo Springs and Playa La Ochenta are located ...
9.4/10 Exceptional! (3 reviews)
"Very clean, owner and staff are amazing, friendly, music, bar and dining area vibes are cheerful atmosphere with friendly staff who make you feel right at home. Highly recommend."

Reviewed on Apr 7, 2025

Hacienda del Sur
Hilton Ponce Golf & Casino Resort
Hilton Ponce Golf & Casino Resort
4.5 out of 5
1150 Caribe Avenue, Ponce
The price is $216 per night from Apr 27 to Apr 28
$216
includes taxes & fees
Apr 27 - Apr 28
Stay at this 4.5-star luxury resort in Ponce. Enjoy free WiFi, 2 outdoor pools, and 4 restaurants. Our guests praise the helpful staff and the clean rooms in ...
8.6/10 Excellent! (1,005 reviews)
"It was"

Reviewed on Apr 9, 2025

Hilton Ponce Golf & Casino Resort
Caribe Hotel Ponce
Caribe Hotel Ponce
3.5 out of 5
103 Turpo Industrial Park, Ponce
The price is $158 per night from Apr 21 to Apr 22
$158
includes taxes & fees
Apr 21 - Apr 22
Stay at this 3.5-star business-friendly hotel in Ponce. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the pool and the helpful ...
8.4/10 Very Good! (1,432 reviews)
"The people that plays real nice"

Reviewed on Apr 13, 2025

Caribe Hotel Ponce
Aloft Ponce Hotel & Casino
Aloft Ponce Hotel & Casino
3.5 out of 5
Street No 2 KM 228.9, Ponce
The price is $188 per night from Apr 24 to Apr 25
$188
includes taxes & fees
Apr 24 - Apr 25
Stay at this 3.5-star hotel in Ponce. Enjoy free parking, 2 outdoor pools, and 4 restaurants. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.4/10 Very Good! (1,001 reviews)
"Nice moder vibe"

Reviewed on Apr 3, 2025

Aloft Ponce Hotel & Casino
Holiday Inn Ponce & Tropical Casino by IHG
Holiday Inn Ponce & Tropical Casino by IHG
3.5 out of 5
3315 Ponce By Pass, Ponce
The price is $141 per night from Apr 28 to Apr 29
$141
includes taxes & fees
Apr 28 - Apr 29
Stay at this 3.5-star hotel in Ponce. Enjoy free WiFi, free parking, and a casino. Our guests praise the helpful staff in our reviews. Popular attractions Playa ...
8.6/10 Excellent! (1,002 reviews)
"Everything was great. We had some small ants. I let the staff know and they thanked me for letting them know. He said he will let management know and it will be taken care of."

Reviewed on Apr 10, 2025

Holiday Inn Ponce & Tropical Casino by IHG
Meliá Century Hotel Ponce
Meliá Century Hotel Ponce
3.5 out of 5
#75 Calle Cristina, Ponce
The price is $129 per night from Apr 27 to Apr 28
$129
includes taxes & fees
Apr 27 - Apr 28
Stay at this 3.5-star business-friendly hotel in Ponce. Enjoy room service, parking (surcharge), and a 24-hour front desk. Popular attractions Parque de Bombas ...
6.4/10 (1,004 reviews)
"Love this place"

Reviewed on Apr 13, 2025

Meliá Century Hotel Ponce
Solace by the Sea
Solace by the Sea
3 out of 5
Highway 2 at km 220.1, Ponce
The price is $129 per night from Apr 17 to Apr 18
$129
includes taxes & fees
Apr 17 - Apr 18
Stay at this 3-star family-friendly hotel in Ponce. Enjoy parking (surcharge), a 24-hour front desk, and daily housekeeping. Popular attractions Playa Cayo Cardona ...
6.2/10 (936 reviews)
"It was close to my family."

Reviewed on Apr 4, 2025

Solace by the Sea
See all 253 properties in Santa Isabel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.