Search Cheap Flights to
Santa Isabel

Photo by Eddie Melendez

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Santa Isabel Flights as Low as $148

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Frontier Airlines
Frontier Airlines
Spirit Airlines
Frontier Airlines
Spirit Airlines
Frontier Airlines
United
JetBlue Airways
Frontier Airlines
Delta
American Airlines
JetBlue Airways
Silver Airways
JetBlue Airways
JetBlue Airways

Cheap Flights to Santa Isabel

Fall in love at first flight with your vacation to Santa Isabel by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santa Isabel on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santa Isabel, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santa Isabel

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santa Isabel with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the SJU airport.

What is the cheapest month to fly to Santa Isabel?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santa Isabel are in May, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santa Isabel?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santa Isabel.

What airport is best to fly into Santa Isabel?

When you’re planning your trip to Santa Isabel, convenience is the name of the game. Luckily, Santa Isabel Mercedita Airport is nearby so you can deplane and get going on checking off everything on your Santa Isabel must-do list.

How much are flights to Santa Isabel?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santa Isabel on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $148, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santa Isabel?

The trick to saving a stack of cash on your flight to Santa Isabel? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $148 right now, why wait?

Santa Isabel Flight Information
Destination airport
Luis Munoz Marin Intl.
Destination airport IATA code
SJU
Roundtrip price
$107

Last Minute Hotel Deals in Santa Isabel

Hotel Las Vegas
Hotel Las Vegas
3 out of 5
PR 153, Km 2.9, Santa Isabel
The price is $100 per night from May 8 to May 9
$100
includes taxes & fees
May 8 - May 9
Stay at this 3-star motel in Santa Isabel. Enjoy 24-hour room service, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and ...
7.8/10 Good! (268 reviews)
"Have a good day and night and good experiences"

Reviewed on May 3, 2025

Hotel Las Vegas
Hacienda del Sur
Hacienda del Sur
2 out of 5
Carr 545 KM 1.5, Sector Gabia, Santa Isabel
The price is $222 per night from Jun 5 to Jun 6
$222
includes taxes & fees
Jun 5 - Jun 6
Stay at this hotel in Santa Isabel. Enjoy free WiFi, free parking, and cable TV channels. Popular attractions Coamo Springs and Playa La Ochenta are located ...
8.6/10 Excellent! (4 reviews)
"Very clean, owner and staff are amazing, friendly, music, bar and dining area vibes are cheerful atmosphere with friendly staff who make you feel right at home. Highly recommend."

Reviewed on Apr 7, 2025

Hacienda del Sur
Hilton Ponce Golf & Casino Resort
Hilton Ponce Golf & Casino Resort
4.5 out of 5
1150 Caribe Avenue, Ponce
The price is $226 per night from May 14 to May 15
$226
includes taxes & fees
May 14 - May 15
Stay at this 4.5-star luxury resort in Ponce. Enjoy free WiFi, 2 outdoor pools, and 4 restaurants. Our guests praise the helpful staff and the clean rooms in ...
8.6/10 Excellent! (1,007 reviews)
"Great experience with awesome staff."

Reviewed on May 3, 2025

Hilton Ponce Golf & Casino Resort
Caribe Hotel Ponce
Caribe Hotel Ponce
3.5 out of 5
103 Turpo Industrial Park, Ponce
The price is $158 per night from May 8 to May 9
$158
includes taxes & fees
May 8 - May 9
Stay at this 3.5-star business-friendly hotel in Ponce. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the pool and the helpful ...
8.4/10 Very Good! (1,461 reviews)
"It was a grate opción for me and my family"

Reviewed on May 5, 2025

Caribe Hotel Ponce
Aloft Ponce Hotel & Casino
Aloft Ponce Hotel & Casino
3.5 out of 5
Street No 2 KM 228.9, Ponce
The price is $188 per night from May 8 to May 9
$188
includes taxes & fees
May 8 - May 9
Stay at this 3.5-star hotel in Ponce. Enjoy free parking, 2 outdoor pools, and 4 restaurants. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.4/10 Very Good! (1,008 reviews)
"Very clean and staff were very friendly"

Reviewed on May 4, 2025

Aloft Ponce Hotel & Casino
Holiday Inn Ponce & Tropical Casino by IHG
Holiday Inn Ponce & Tropical Casino by IHG
3.5 out of 5
3315 Ponce By Pass, Ponce
The price is $141 per night from May 19 to May 20
$141
includes taxes & fees
May 19 - May 20
Stay at this 3.5-star hotel in Ponce. Enjoy free WiFi, free parking, and a casino. Our guests praise the helpful staff in our reviews. Popular attractions Playa ...
8.6/10 Excellent! (1,009 reviews)
"excellent"

Reviewed on May 4, 2025

Holiday Inn Ponce & Tropical Casino by IHG
The Fox Hotel
The Fox Hotel
3.5 out of 5
6963 Calle Isabel Munoz Rivera, Ponce, Puerto Rico
Stay at this 3.5-star hotel in Ponce. Enjoy 4 restaurants, 3 bars/lounges, and a 24-hour front desk. Popular attractions Plaza of Delights and Parque de Bombas ...
7.2/10 Good! (766 reviews)
"Great"

Reviewed on May 5, 2025

The Fox Hotel
Meliá Century Hotel Ponce
Meliá Century Hotel Ponce
3.5 out of 5
#75 Calle Cristina, Ponce
The price is $155 per night from Jun 1 to Jun 2
$155
includes taxes & fees
Jun 1 - Jun 2
Stay at this 3.5-star business-friendly hotel in Ponce. Enjoy room service, parking (surcharge), and a 24-hour front desk. Popular attractions Parque de Bombas ...
6.4/10 (1,011 reviews)
"Everything is good."

Reviewed on May 4, 2025

Meliá Century Hotel Ponce
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.