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Hotels in Santa Isabel

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Choose from 261 Santa Isabel Hotel Deals

Hotel Las Vegas
Hotel Las Vegas
3 out of 5
PR 153, Km 2.9, Santa Isabel
  • 4 min drive from Carribbean Cinemas Santa Isabel
Stay at this 3-star motel in Santa Isabel. Enjoy 24-hour room service, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and ...
7.8/10 Good! (277 reviews)
"Fuimos de un día para otro por mi graduación el lugar estaba muy limpio y el servicio por parte de todos fue excelente y muy amables de verdad nos gustó mucho"

Reviewed on May 30, 2025

Hotel Las Vegas
Hacienda del Sur
Hacienda del Sur
2 out of 5
Carr 545 KM 1.5, Sector Gabia, Santa Isabel
  • 26 min walk from Carribbean Cinemas Santa Isabel
Stay at this hotel in Santa Isabel. Enjoy free WiFi, free parking, and cable TV channels. Popular attractions Carribbean Cinemas Santa Isabel and Coamo Springs ...
9.2/10 Wonderful! (7 reviews)
"Great place !!!!! Beautiful and clean !! Staff was very friendly !!! Great for relaxing at the pool, playing beach tennis , pickleball or tennis."

Reviewed on May 26, 2025

Hacienda del Sur
Hilton Ponce Golf & Casino Resort
Hilton Ponce Golf & Casino Resort
4.5 out of 5
1150 Caribe Avenue, Ponce
  • 25 min drive from Carribbean Cinemas Santa Isabel
Stay at this 4.5-star luxury resort in Ponce. Enjoy free WiFi, 2 outdoor pools, and 4 restaurants. Our guests praise the helpful staff and the clean rooms in ...
8.6/10 Excellent! (1,004 reviews)
"Everything was perfect, from the room, pools, breakfast, attention... everything!!!"

Reviewed on May 30, 2025

Hilton Ponce Golf & Casino Resort
Caribe Hotel Ponce
Caribe Hotel Ponce
3.5 out of 5
103 Turpo Industrial Park, Ponce
  • 22 min drive from Carribbean Cinemas Santa Isabel
Stay at this 3.5-star business-friendly hotel in Ponce. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the pool and the helpful ...
8.4/10 Very Good! (1,504 reviews)
"Good"

Reviewed on Jun 1, 2025

Caribe Hotel Ponce
Aloft Ponce Hotel & Casino
Aloft Ponce Hotel & Casino
3.5 out of 5
Street No 2 KM 228.9, Ponce
  • 25 min drive from Carribbean Cinemas Santa Isabel
Stay at this 3.5-star hotel in Ponce. Enjoy free parking, 2 outdoor pools, and 4 restaurants. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.4/10 Very Good! (1,001 reviews)
"Comfy bed, good location"

Reviewed on May 25, 2025

Aloft Ponce Hotel & Casino
Holiday Inn Ponce & Tropical Casino by IHG
Holiday Inn Ponce & Tropical Casino by IHG
3.5 out of 5
3315 Ponce By Pass, Ponce
  • 32 min drive from Carribbean Cinemas Santa Isabel
Stay at this 3.5-star hotel in Ponce. Enjoy free WiFi, free parking, and a casino. Our guests praise the helpful staff in our reviews. Popular attractions Carribbean ...
8.6/10 Excellent! (1,003 reviews)
"Pobre la calidad del restaurante"

Reviewed on Jun 1, 2025

Holiday Inn Ponce & Tropical Casino by IHG
The Fox Hotel
The Fox Hotel
3.5 out of 5
6963 Calle Isabel Munoz Rivera, Ponce, Puerto Rico
  • 26 min drive from Carribbean Cinemas Santa Isabel
Stay at this 3.5-star hotel in Ponce. Enjoy 4 restaurants, 3 bars/lounges, and a 24-hour front desk. Popular attractions Plaza of Delights and Parque de Bombas ...
7.2/10 Good! (786 reviews)
"I stayed at this hotel for 2 nights and really enjoyed it. They have an arcade and a bar downstairs as well as food stands inside and outside... my room was right next to the stairs and i had no issues with noise downstairs.. my only complaint would be the lack of water pressure in the shower and ..."

Reviewed on May 26, 2025

The Fox Hotel
Meliá Century Hotel Ponce
Meliá Century Hotel Ponce
3.5 out of 5
#75 Calle Cristina, Ponce
  • 26 min drive from Carribbean Cinemas Santa Isabel
Stay at this 3.5-star business-friendly hotel in Ponce. Enjoy room service, parking (surcharge), and a 24-hour front desk. Popular attractions Parque de Bombas ...
6.4/10 (1,001 reviews)
"Las sábanas huelen mucho a Clorox. La alfombra y el mueble necesita limpieza."

Reviewed on Jun 1, 2025

Meliá Century Hotel Ponce
Ponce Plaza Hotel & Casino
Ponce Plaza Hotel & Casino
3.5 out of 5
Reina Street, Ponce
  • 26 min drive from Carribbean Cinemas Santa Isabel
Stay at this 3.5-star historic hotel in Ponce. Enjoy free WiFi, a casino, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms ...
8.8/10 Excellent! (1,002 reviews)
"Friendly atmosphere."

Reviewed on May 21, 2025

Ponce Plaza Hotel & Casino
Hotel Nuevo Mejico
Hotel Nuevo Mejico
3.5 out of 5
PR-501, Km 1.4, Ponce, Ponce
  • 31 min drive from Carribbean Cinemas Santa Isabel
Stay at this 3.5-star motel in Ponce. Enjoy free WiFi, free parking, and 24-hour room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.8/10 Good! (608 reviews)
"Very clean, the staff very friendly"

Reviewed on May 23, 2025

Hotel Nuevo Mejico
Hotel El Eden
Hotel El Eden
3 out of 5
Carr 149, Km 4.6, Juana Diaz
  • 15 min drive from Carribbean Cinemas Santa Isabel
Stay at this 3-star motel in Juana Diaz. Enjoy free WiFi, 24-hour room service, and a 24-hour front desk. Our guests praise the helpful staff in our ...
8.4/10 Very Good! (484 reviews)
"Everything was fine"

Reviewed on May 18, 2025

Hotel El Eden
The Place at the Sea
The Place at the Sea
2 out of 5
3499 Av. Los Meros, Ponce, Ponce
  • 28 min drive from Carribbean Cinemas Santa Isabel
Stay at this aparthotel in Ponce. Enjoy free WiFi, free parking, and a garden. Popular attractions Carribbean Cinemas Ponce Towne and Vicens Coliseum are located ...
9/10 Wonderful! (129 reviews)
"Buen lugar tranquilo y el dueño tremenda persona y sociable..."

Reviewed on May 30, 2025

The Place at the Sea
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Santa Isabel

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Santa Isabel.

Choosing the right hotel in has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Santa Isabel’s 261 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $100. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Santa Isabel hotel deals at the last minute.

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Frequently Asked Questions About Santa Isabel hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Santa Isabel?

With over 261 hotels in Santa Isabel, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $100.

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