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Santiago

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Santiago Flights as Low as $320

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Viva
Mon, Sep 21 - Thu, Oct 1
IAH
George Bush Intercontinental
MTY
General Mariano Escobedo Intl.
$320 Roundtrip, found 23 hours ago
$320
Roundtrip
found 23 hours ago
Select Viva flight, departing Mon, Sep 21 from George Bush Intercontinental to General Mariano Escobedo Intl., returning Thu, Oct 1, priced at $320 found 23 hours ago
Viva
Sun, Sep 13 - Thu, Sep 24
LAX
Los Angeles Intl.
MTY
General Mariano Escobedo Intl.
$325 Roundtrip, found 1 day ago
$325
Roundtrip
found 1 day ago
Select Viva flight, departing Sun, Sep 13 from Los Angeles Intl. to General Mariano Escobedo Intl., returning Thu, Sep 24, priced at $325 found 1 day ago
Delta
Mon, Sep 21 - Thu, Oct 1
IAH
George Bush Intercontinental
MTY
General Mariano Escobedo Intl.
$325 Roundtrip, found 23 hours ago
$325
Roundtrip
found 23 hours ago
Select Delta flight, departing Mon, Sep 21 from George Bush Intercontinental to General Mariano Escobedo Intl., returning Thu, Oct 1, priced at $325 found 23 hours ago
Viva
Tue, Sep 1 - Thu, Sep 10
IAH
George Bush Intercontinental
MTY
General Mariano Escobedo Intl.
$328 Roundtrip, found 10 hours ago
$328
Roundtrip
found 10 hours ago
Select Viva flight, departing Tue, Sep 1 from George Bush Intercontinental to General Mariano Escobedo Intl., returning Thu, Sep 10, priced at $328 found 10 hours ago
Viva
Mon, Sep 21 - Thu, Oct 1
IAH
George Bush Intercontinental
MTY
General Mariano Escobedo Intl.
$329 Roundtrip, found 23 hours ago
$329
Roundtrip
found 23 hours ago
Select Viva flight, departing Mon, Sep 21 from George Bush Intercontinental to General Mariano Escobedo Intl., returning Thu, Oct 1, priced at $329 found 23 hours ago
Viva
Sat, Sep 12 - Thu, Sep 24
LAX
Los Angeles Intl.
MTY
General Mariano Escobedo Intl.
$337 Roundtrip, found 1 day ago
$337
Roundtrip
found 1 day ago
Select Viva flight, departing Sat, Sep 12 from Los Angeles Intl. to General Mariano Escobedo Intl., returning Thu, Sep 24, priced at $337 found 1 day ago
United
Mon, Sep 21 - Thu, Oct 1
IAH
George Bush Intercontinental
MTY
General Mariano Escobedo Intl.
$342 Roundtrip, found 23 hours ago
$342
Roundtrip
found 23 hours ago
Select United flight, departing Mon, Sep 21 from George Bush Intercontinental to General Mariano Escobedo Intl., returning Thu, Oct 1, priced at $342 found 23 hours ago
Delta
Mon, Sep 21 - Thu, Oct 1
IAH
George Bush Intercontinental
MTY
General Mariano Escobedo Intl.
$347 Roundtrip, found 23 hours ago
$347
Roundtrip
found 23 hours ago
Select Delta flight, departing Mon, Sep 21 from George Bush Intercontinental to General Mariano Escobedo Intl., returning Thu, Oct 1, priced at $347 found 23 hours ago
Aeromexico
Thu, Sep 24 - Mon, Sep 28
IAH
George Bush Intercontinental
MTY
General Mariano Escobedo Intl.
$347 Roundtrip, found 23 hours ago
$347
Roundtrip
found 23 hours ago
Select Aeromexico flight, departing Thu, Sep 24 from George Bush Intercontinental to General Mariano Escobedo Intl., returning Mon, Sep 28, priced at $347 found 23 hours ago
American Airlines
Mon, Sep 21 - Thu, Oct 1
IAH
George Bush Intercontinental
MTY
General Mariano Escobedo Intl.
$415 Roundtrip, found 23 hours ago
$415
Roundtrip
found 23 hours ago
Select American Airlines flight, departing Mon, Sep 21 from George Bush Intercontinental to General Mariano Escobedo Intl., returning Thu, Oct 1, priced at $415 found 23 hours ago
Volaris
Tue, Sep 1 - Thu, Sep 10
IAH
George Bush Intercontinental
MTY
General Mariano Escobedo Intl.
$429 Roundtrip, found 10 hours ago
$429
Roundtrip
found 10 hours ago
Select Volaris flight, departing Tue, Sep 1 from George Bush Intercontinental to General Mariano Escobedo Intl., returning Thu, Sep 10, priced at $429 found 10 hours ago
Air Canada
Mon, Sep 7 - Fri, Sep 11
DTW
Detroit Metropolitan Wayne County
MTY
General Mariano Escobedo Intl.
$533 Roundtrip, found 18 hours ago
$533
Roundtrip
found 18 hours ago
Select Air Canada flight, departing Mon, Sep 7 from Detroit Metropolitan Wayne County to General Mariano Escobedo Intl., returning Fri, Sep 11, priced at $533 found 18 hours ago
Delta
Mon, Nov 23 - Wed, Dec 2
EWR
Newark Liberty Intl. Airport
MTY
General Mariano Escobedo Intl.
$534 Roundtrip, found 1 day ago
$534
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Nov 23 from Newark Liberty Intl. Airport to General Mariano Escobedo Intl., returning Wed, Dec 2, priced at $534 found 1 day ago
Air Canada
Sat, Sep 12 - Mon, Sep 28
DTW
Detroit Metropolitan Wayne County
MTY
General Mariano Escobedo Intl.
$557 Roundtrip, found 18 hours ago
$557
Roundtrip
found 18 hours ago
Select Air Canada flight, departing Sat, Sep 12 from Detroit Metropolitan Wayne County to General Mariano Escobedo Intl., returning Mon, Sep 28, priced at $557 found 18 hours ago
Delta
Mon, Dec 7 - Tue, Dec 15
OMA
Eppley Field
MTY
General Mariano Escobedo Intl.
$646 Roundtrip, found 1 day ago
$646
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Dec 7 from Eppley Field to General Mariano Escobedo Intl., returning Tue, Dec 15, priced at $646 found 1 day ago
American Airlines
Sat, Sep 12 - Sat, Sep 26
CLD
McClellan-Palomar
MTY
General Mariano Escobedo Intl.
$779 Roundtrip, found 1 day ago
$779
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Sep 12 from McClellan-Palomar to General Mariano Escobedo Intl., returning Sat, Sep 26, priced at $779 found 1 day ago

Cheap Flights to Santiago

Fall in love at first flight with your vacation to Santiago by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santiago on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santiago, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santiago

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santiago with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MTY airport.

What is the cheapest month to fly to Santiago?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santiago are in September, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santiago?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santiago.

What airport is best to fly into Santiago?

When you’re planning your trip to Santiago, convenience is the name of the game. Luckily, Santiago General Mariano Escobedo Intl. Airport is nearby so you can deplane and get going on checking off everything on your Santiago must-do list.

How much are flights to Santiago?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santiago on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $320, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santiago?

The trick to saving a stack of cash on your flight to Santiago? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $320 right now, why wait?

Santiago Flight Information
Destination airport
General Mariano Escobedo Intl.
Destination airport IATA code
MTY
Roundtrip price
$319

Last Minute Hotel Deals in Santiago

Gamma Monterrey Rincón de Santiago.

Gamma Monterrey Rincón de Santiago.

3.5 out of 5
Camino La Cortina No. 119-122 Santiago NL
Book a stay at this spa hotel in Santiago. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the helpful staff in our reviews. Popular attractions ...
9/10 Wonderful! (629 reviews)
"Everything clean"

Reviewed on Aug 16, 2026

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Gamma Monterrey Rincón de Santiago.
Bahía Escondida

Bahía Escondida

3 out of 5
Falda Cerro de la Ermita, 1010 Santiago NL
Book a stay at this spa hotel in Santiago. Enjoy free WiFi, free parking, and 3 outdoor pools. Popular attractions Presa La Boca and Bungee Cola de Caballo are ...
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Bahía Escondida
El Cielo de Santiago

El Cielo de Santiago

2 out of 5
305 Calle de las sandias Santiago NL
Stay at this hotel in Santiago. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Cascada Cola de Caballo and Cumbres de Monterrey ...
10/10 Exceptional! (2 reviews)
"Room was clean and it was very nice. Only thing was that it didnt have a key to lock it even though nothing was stolen. But would like privacy and should be given a key."

Reviewed on Aug 28, 2026

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El Cielo de Santiago
Safi Royal Luxury Metropolitan

Safi Royal Luxury Metropolitan

4.5 out of 5
2400 Av Lázaro Cárdenas San Pedro Garza García NL
Book a stay at this luxury hotel in San Pedro Garza García. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our ...
9.4/10 Exceptional! (3,015 reviews)
"I understand the big city is more expensive. But, having to literally pay for everything at a hotel gets under my skin a little bit. And if they are to charge for everything - why stadium prices for a beer or two to the room: $19 USD! I cannot deny the absolute beauty and glamour of the hotel though ..."

Reviewed on Aug 28, 2026

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Safi Royal Luxury Metropolitan
Safi Royal Luxury Centro

Safi Royal Luxury Centro

4 out of 5
Pino Suarez No. 444 Sur, Colonia Centro Monterrey NL
Book a stay at this family-friendly hotel in Monterrey. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.8/10 Excellent! (2,914 reviews)
"Clean room Staff Breakfast Bar"

Reviewed on Aug 29, 2026

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Safi Royal Luxury Centro
Antaris Cintermex

Antaris Cintermex

3 out of 5
Avenida Funidora 500 Monterrey NL
Book a stay at this business-friendly hotel in Monterrey. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
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Antaris Cintermex
Antaris Galerías

Antaris Galerías

3.5 out of 5
Ave Constitucion 1707 Pte Col: Mirador Monterrey NL
Book a stay at this business-friendly hotel in Monterrey. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (2,861 reviews)
"Great location, the staff was very friendly and helpful, great value."

Reviewed on Aug 28, 2026

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Antaris Galerías
Camino Real Fashion Drive Monterrey

Camino Real Fashion Drive Monterrey

4.5 out of 5
Lázaro Cárdenas 1002 Del, Valle Oriente San Pedro Garza García NL
Book a stay at this luxury hotel in San Pedro Garza García. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff ...
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Camino Real Fashion Drive Monterrey
See all 833 properties in Santiago
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.