Search Cheap Flights to
Southeast Ohio

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Southeast Ohio Flights as Low as $252

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Sun, Feb 15 - Thu, Feb 19
MSP
Minneapolis - St. Paul Intl.
CMH
John Glenn Columbus Intl.
$252 Roundtrip, found 1 day ago
$252
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sun, Feb 15 from Minneapolis - St. Paul Intl. to John Glenn Columbus Intl., returning Thu, Feb 19, priced at $252 found 1 day ago
Bargain Flight
Sat, Mar 7 - Wed, Mar 11
MSP
Minneapolis - St. Paul Intl.
CMH
John Glenn Columbus Intl.
$256 Roundtrip, found 4 days ago
$256
Roundtrip
found 4 days ago
Select Bargain Flight flight, departing Sat, Mar 7 from Minneapolis - St. Paul Intl. to John Glenn Columbus Intl., returning Wed, Mar 11, priced at $256 found 4 days ago
Bargain Flight
Fri, Feb 13 - Sun, Feb 15
MSP
Minneapolis - St. Paul Intl.
CMH
John Glenn Columbus Intl.
$257 Roundtrip, found 1 day ago
$257
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Fri, Feb 13 from Minneapolis - St. Paul Intl. to John Glenn Columbus Intl., returning Sun, Feb 15, priced at $257 found 1 day ago
Frontier Airlines
Mon, Feb 16 - Thu, Feb 19
MSP
Minneapolis - St. Paul Intl.
CMH
John Glenn Columbus Intl.
$277 Roundtrip, found 1 day ago
$277
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, Feb 16 from Minneapolis - St. Paul Intl. to John Glenn Columbus Intl., returning Thu, Feb 19, priced at $277 found 1 day ago
Frontier Airlines
Sun, Feb 15 - Sun, Feb 22
MSP
Minneapolis - St. Paul Intl.
CMH
John Glenn Columbus Intl.
$284 Roundtrip, found 1 day ago
$284
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sun, Feb 15 from Minneapolis - St. Paul Intl. to John Glenn Columbus Intl., returning Sun, Feb 22, priced at $284 found 1 day ago
Frontier Airlines
Sun, Feb 15 - Mon, Feb 23
MSP
Minneapolis - St. Paul Intl.
CMH
John Glenn Columbus Intl.
$310 Roundtrip, found 1 day ago
$310
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sun, Feb 15 from Minneapolis - St. Paul Intl. to John Glenn Columbus Intl., returning Mon, Feb 23, priced at $310 found 1 day ago
Frontier Airlines
Mon, Feb 16 - Sun, Feb 22
MSP
Minneapolis - St. Paul Intl.
CMH
John Glenn Columbus Intl.
$313 Roundtrip, found 1 day ago
$313
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, Feb 16 from Minneapolis - St. Paul Intl. to John Glenn Columbus Intl., returning Sun, Feb 22, priced at $313 found 1 day ago
Frontier Airlines
Thu, Feb 12 - Thu, Feb 19
MSP
Minneapolis - St. Paul Intl.
CMH
John Glenn Columbus Intl.
$318 Roundtrip, found 1 day ago
$318
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Feb 12 from Minneapolis - St. Paul Intl. to John Glenn Columbus Intl., returning Thu, Feb 19, priced at $318 found 1 day ago
Frontier Airlines
Mon, Feb 16 - Mon, Feb 23
MSP
Minneapolis - St. Paul Intl.
CMH
John Glenn Columbus Intl.
$340 Roundtrip, found 1 day ago
$340
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, Feb 16 from Minneapolis - St. Paul Intl. to John Glenn Columbus Intl., returning Mon, Feb 23, priced at $340 found 1 day ago
Frontier Airlines
Thu, Feb 12 - Sun, Feb 22
MSP
Minneapolis - St. Paul Intl.
CMH
John Glenn Columbus Intl.
$354 Roundtrip, found 1 day ago
$354
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Feb 12 from Minneapolis - St. Paul Intl. to John Glenn Columbus Intl., returning Sun, Feb 22, priced at $354 found 1 day ago
Frontier Airlines
Sun, Feb 15 - Mon, Feb 16
MSP
Minneapolis - St. Paul Intl.
CMH
John Glenn Columbus Intl.
$358 Roundtrip, found 1 day ago
$358
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sun, Feb 15 from Minneapolis - St. Paul Intl. to John Glenn Columbus Intl., returning Mon, Feb 16, priced at $358 found 1 day ago
American Airlines
Sat, Apr 18 - Wed, Apr 22
MSP
Minneapolis - St. Paul Intl.
HTS
Tri-State
$358 Roundtrip, found 23 hours ago
$358
Roundtrip
found 23 hours ago
Select American Airlines flight, departing Sat, Apr 18 from Minneapolis - St. Paul Intl. to Tri-State, returning Wed, Apr 22, priced at $358 found 23 hours ago
Frontier Airlines
Thu, Feb 12 - Mon, Feb 23
MSP
Minneapolis - St. Paul Intl.
CMH
John Glenn Columbus Intl.
$381 Roundtrip, found 1 day ago
$381
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Feb 12 from Minneapolis - St. Paul Intl. to John Glenn Columbus Intl., returning Mon, Feb 23, priced at $381 found 1 day ago
American Airlines
Sat, Mar 7 - Wed, Mar 11
MSP
Minneapolis - St. Paul Intl.
CMH
John Glenn Columbus Intl.
$390 Roundtrip, found 4 days ago
$390
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Mar 7 from Minneapolis - St. Paul Intl. to John Glenn Columbus Intl., returning Wed, Mar 11, priced at $390 found 4 days ago
Frontier Airlines
Thu, Feb 12 - Sun, Feb 15
MSP
Minneapolis - St. Paul Intl.
CMH
John Glenn Columbus Intl.
$400 Roundtrip, found 1 day ago
$400
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Feb 12 from Minneapolis - St. Paul Intl. to John Glenn Columbus Intl., returning Sun, Feb 15, priced at $400 found 1 day ago
Delta
Sun, Mar 8 - Mon, Mar 16
MSP
Minneapolis - St. Paul Intl.
CMH
John Glenn Columbus Intl.
$419 Roundtrip, found 17 hours ago
$419
Roundtrip
found 17 hours ago
Select Delta flight, departing Sun, Mar 8 from Minneapolis - St. Paul Intl. to John Glenn Columbus Intl., returning Mon, Mar 16, priced at $419 found 17 hours ago

Cheap Flights to Southeast Ohio

Fall in love at first flight with your vacation to Southeast Ohio by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Southeast Ohio on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Southeast Ohio, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Southeast Ohio

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Southeast Ohio with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the CMH airport.

What is the cheapest month to fly to Southeast Ohio?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Southeast Ohio are in February, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Southeast Ohio?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 14 to choose from for your flight to Southeast Ohio.

What airport is best to fly into Southeast Ohio?

When you’re planning your trip to Southeast Ohio, convenience is the name of the game. Luckily, Southeast Ohio Mid-Ohio Valley Regional Airport is nearby so you can deplane and get going on checking off everything on your Southeast Ohio must-do list.

How much are flights to Southeast Ohio?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Southeast Ohio on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $252, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Southeast Ohio?

The trick to saving a stack of cash on your flight to Southeast Ohio? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $252 right now, why wait?

Southeast Ohio Flight Information
Destination airport
John Glenn Columbus Intl.
Destination airport IATA code
CMH
Roundtrip price
$68

Last Minute Hotel Deals in Southeast Ohio

Wingate by Wyndham St. Clairsville/Wheeling

Wingate by Wyndham St. Clairsville/Wheeling

2.5 out of 5
51130 National Road E St. Clairsville OH
Book a stay at this business-friendly hotel in St. Clairsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
9/10 Wonderful! (981 reviews)
The Breakfast had a wide variety of options which is good for many different peoples needs. The hot tub was great but the pool was not heated which was not good when asked the front desk said waiting for it to be repaired. Should put that in the booking site though as some people only book for the ...

Reviewed on Jan 20, 2026

Get rates
Wingate by Wyndham St. Clairsville/Wheeling
The Lodge at Hocking College

The Lodge at Hocking College

2.5 out of 5
15770 OH-691 Nelsonville OH
Book a stay at this business-friendly hotel in Nelsonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (868 reviews)
The lodge sitting area was nice with the fireplace and music. The beds were very comfortable. Quiet rooms.

Reviewed on Jan 19, 2026

Get rates
The Lodge at Hocking College
Days Inn by Wyndham Columbus East Airport

Days Inn by Wyndham Columbus East Airport

2.5 out of 5
2100 Brice Road Reynoldsburg OH
Book a stay at this business-friendly hotel in Reynoldsburg. Enjoy an outdoor pool, room service, and a 24-hour front desk. Our guests praise the helpful staff ...
7.4/10 Good! (1,002 reviews)
Very clean

Reviewed on Jan 18, 2026

Get rates
Days Inn by Wyndham Columbus East Airport
Ohio University Inn & Conference Center

Ohio University Inn & Conference Center

3.5 out of 5
331 Richland Ave Athens OH
Book a stay at this business-friendly hotel in Athens. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,000 reviews)
Quiet and clean room, well prepared and great location

Reviewed on Jan 20, 2026

Get rates
Ohio University Inn & Conference Center
DogHouse Columbus

DogHouse Columbus

2.5 out of 5
100 Gender Road Canal Winchester OH
Book a stay at this business-friendly hotel in Canal Winchester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,005 reviews)
Hallways showed a little aging. Could use automatic doors so you can get your luggage out to the parking lot on the luggage cart.

Reviewed on Jan 22, 2026

Get rates
DogHouse Columbus
Christopher Inn and Suites

Christopher Inn and Suites

2.5 out of 5
30 North Plaza Boulevard Chillicothe OH
Book a stay at this business-friendly hotel in Chillicothe. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in ...
9/10 Wonderful! (1,149 reviews)
The room was clean and comfortable

Reviewed on Jan 17, 2026

Get rates
Christopher Inn and Suites
Holiday Inn Express Circleville by IHG

Holiday Inn Express Circleville by IHG

2.5 out of 5
23911 Us Rt 23 S Circleville OH
Book a stay at this business-friendly hotel in Circleville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (652 reviews)
Id give it a 5 star but they need to upgarde the hotel doors so i dont have to keep going to the receptionist to reset my card but all in all agood stay and staff very friendly will stay here again if i co e back

Reviewed on Jan 12, 2026

Get rates
Holiday Inn Express Circleville by IHG
Quality Inn & Suites Zanesville City Center

Quality Inn & Suites Zanesville City Center

2.5 out of 5
500 Monroe St Zanesville OH
Book a stay at this business-friendly hotel in Zanesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (517 reviews)
Staff was very friendly. Room was clean and bed was very comfortable. Breakfast was good options. Loved the hot tea and coffee available all day.

Reviewed on Jan 14, 2026

Get rates
Quality Inn & Suites Zanesville City Center
See all 2,930 properties in Southeast Ohio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Hotels With Free Airport Shuttle

Baymont by Wyndham Columbus/Rickenbacker

Baymont by Wyndham Columbus/Rickenbacker

2.5 out of 5
2323 Rickenbacker Parkway West Columbus OH
Book a stay at this business-friendly hotel in Columbus. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Scioto Downs and Motts Military ...
5.8/10 (1,002 reviews)
Yes

Reviewed on Dec 15, 2025

Get rates
Baymont by Wyndham Columbus/Rickenbacker
Fairfield Inn and Suites by Marriott Wheeling St Clairsville

Fairfield Inn and Suites by Marriott Wheeling St Clairsville

2.5 out of 5
67731 Mall Road St. Clairsville OH
Book a stay at this business-friendly hotel in St. Clairsville. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff in ...
8.2/10 Very Good! (420 reviews)
Room was clean and comfortable. Mark at the front desk was very helpful and his customer service is top tier. Breakfast is good as well.

Reviewed on Dec 9, 2025

Get rates
Fairfield Inn and Suites by Marriott Wheeling St Clairsville
The Lafayette A grand Riverboat Era Hotel

The Lafayette A grand Riverboat Era Hotel

3 out of 5
101 Front St Marietta OH
Book a stay at this business-friendly hotel in Marietta. Enjoy free WiFi, free parking, and a rooftop terrace. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,003 reviews)
Sentimental for us, since we honeymooned there 25 years ago. Bed was way too soft for my liking, but the view of the river was great. Not handicapped accessible where we were, but we got help.

Reviewed on Jan 20, 2026

Get rates
The Lafayette A grand Riverboat Era Hotel
See all 2,930 properties in Southeast Ohio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.