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Tupelo

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Tupelo Flights as Low as $245

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Tue, Aug 5 - Tue, Aug 12
ORD
O'Hare Intl.
TUP
Tupelo Regional
$245 Roundtrip, just found
$245
Roundtrip
just found
Select American Airlines flight, departing Tue, Aug 5 from O'Hare Intl. to Tupelo Regional, returning Tue, Aug 12, priced at $245 just found
American Airlines
Tue, Aug 5 - Sat, Aug 9
ORD
O'Hare Intl.
TUP
Tupelo Regional
$274 Roundtrip, found 4 days ago
$274
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Aug 5 from O'Hare Intl. to Tupelo Regional, returning Sat, Aug 9, priced at $274 found 4 days ago
American Airlines
Sat, Aug 2 - Thu, Aug 7
ORD
O'Hare Intl.
TUP
Tupelo Regional
$277 Roundtrip, found 4 days ago
$277
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Aug 2 from O'Hare Intl. to Tupelo Regional, returning Thu, Aug 7, priced at $277 found 4 days ago
American Airlines
Sat, Aug 2 - Sat, Aug 9
ORD
O'Hare Intl.
TUP
Tupelo Regional
$297 Roundtrip, found 2 days ago
$297
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Aug 2 from O'Hare Intl. to Tupelo Regional, returning Sat, Aug 9, priced at $297 found 2 days ago
American Airlines
Mon, Aug 4 - Sun, Aug 10
ORD
O'Hare Intl.
TUP
Tupelo Regional
$300 Roundtrip, found 4 days ago
$300
Roundtrip
found 4 days ago
Select American Airlines flight, departing Mon, Aug 4 from O'Hare Intl. to Tupelo Regional, returning Sun, Aug 10, priced at $300 found 4 days ago
Contour Airlines
Wed, Aug 6 - Thu, Aug 7
ORD
O'Hare Intl.
TUP
Tupelo Regional
$303 Roundtrip, found 2 days ago
$303
Roundtrip
found 2 days ago
Select Contour Airlines flight, departing Wed, Aug 6 from O'Hare Intl. to Tupelo Regional, returning Thu, Aug 7, priced at $303 found 2 days ago
American Airlines
Tue, Aug 5 - Tue, Aug 12
ORD
O'Hare Intl.
TUP
Tupelo Regional
$309 Roundtrip, just found
$309
Roundtrip
just found
Select American Airlines flight, departing Tue, Aug 5 from O'Hare Intl. to Tupelo Regional, returning Tue, Aug 12, priced at $309 just found
American Airlines
Mon, Aug 4 - Sun, Aug 10
ORD
O'Hare Intl.
TUP
Tupelo Regional
$310 Roundtrip, found 6 days ago
$310
Roundtrip
found 6 days ago
Select American Airlines flight, departing Mon, Aug 4 from O'Hare Intl. to Tupelo Regional, returning Sun, Aug 10, priced at $310 found 6 days ago
American Airlines
Sun, Aug 3 - Sat, Aug 9
ORD
O'Hare Intl.
TUP
Tupelo Regional
$316 Roundtrip, found 2 days ago
$316
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sun, Aug 3 from O'Hare Intl. to Tupelo Regional, returning Sat, Aug 9, priced at $316 found 2 days ago
American Airlines
Tue, Aug 5 - Tue, Aug 12
ORD
O'Hare Intl.
TUP
Tupelo Regional
$319 Roundtrip, found 1 day ago
$319
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Aug 5 from O'Hare Intl. to Tupelo Regional, returning Tue, Aug 12, priced at $319 found 1 day ago
American Airlines
Tue, Aug 5 - Tue, Aug 12
ORD
O'Hare Intl.
TUP
Tupelo Regional
$323 Roundtrip, found 3 days ago
$323
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Aug 5 from O'Hare Intl. to Tupelo Regional, returning Tue, Aug 12, priced at $323 found 3 days ago
American Airlines
Thu, Aug 7 - Sun, Aug 10
ORD
O'Hare Intl.
TUP
Tupelo Regional
$327 Roundtrip, found 3 days ago
$327
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Aug 7 from O'Hare Intl. to Tupelo Regional, returning Sun, Aug 10, priced at $327 found 3 days ago
American Airlines
Wed, Aug 6 - Thu, Aug 7
ORD
O'Hare Intl.
TUP
Tupelo Regional
$328 Roundtrip, found 5 days ago
$328
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Aug 6 from O'Hare Intl. to Tupelo Regional, returning Thu, Aug 7, priced at $328 found 5 days ago
United
Tue, Aug 5 - Tue, Aug 12
ORD
O'Hare Intl.
TUP
Tupelo Regional
$333 Roundtrip, just found
$333
Roundtrip
just found
Select United flight, departing Tue, Aug 5 from O'Hare Intl. to Tupelo Regional, returning Tue, Aug 12, priced at $333 just found
Contour Airlines
Wed, Aug 6 - Thu, Aug 7
ORD
O'Hare Intl.
TUP
Tupelo Regional
$334 Roundtrip, found 2 days ago
$334
Roundtrip
found 2 days ago
Select Contour Airlines flight, departing Wed, Aug 6 from O'Hare Intl. to Tupelo Regional, returning Thu, Aug 7, priced at $334 found 2 days ago
United
Thu, Jun 19 - Tue, Jun 24
CMH
John Glenn Columbus Intl.
TUP
Tupelo Regional
$769 Roundtrip, found 1 day ago
$769
Roundtrip
found 1 day ago
Select United flight, departing Thu, Jun 19 from John Glenn Columbus Intl. to Tupelo Regional, returning Tue, Jun 24, priced at $769 found 1 day ago

Cheap Flights to Tupelo

Fall in love at first flight with your vacation to Tupelo by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Tupelo on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Tupelo, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Tupelo

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Tupelo with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the TUP airport.

What is the cheapest month to fly to Tupelo?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Tupelo are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Tupelo?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Tupelo.

What airport is best to fly into Tupelo?

When you’re planning your trip to Tupelo, convenience is the name of the game. Luckily, Tupelo Tupelo Regional Airport is nearby so you can deplane and get going on checking off everything on your Tupelo must-do list.

How much are flights to Tupelo?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Tupelo on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $245, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Tupelo?

The trick to saving a stack of cash on your flight to Tupelo? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $245 right now, why wait?

Tupelo Flight Information
Destination airport
Tupelo Regional
Destination airport IATA code
TUP
Roundtrip price
$443

Last Minute Hotel Deals in Tupelo

Baymont by Wyndham Tupelo
Baymont by Wyndham Tupelo
2.5 out of 5
625 Spicer Drive, Tupelo, MS
Book a stay at this business-friendly motel in Tupelo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.4/10 Good! (880 reviews)
"One night stop over due to flight issue"

Reviewed on Jun 11, 2025

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Baymont by Wyndham Tupelo
Red Roof Inn Tupelo
Red Roof Inn Tupelo
2 out of 5
1516 Mccullough Blvd, Tupelo, MS
Book a stay at this business-friendly hotel in Tupelo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.2/10 Very Good! (1,005 reviews)
"It was so clean! If you don't want a room with the door on the outside, you have to request an interior room. It is in a totally different building right around the corner. The building is key entry so anyone can't walk in. The staff was very kind. The breakfast is small though. That's the only thing ..."

Reviewed on Jun 13, 2025

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Red Roof Inn Tupelo
La Quinta Inn & Suites by Wyndham Tupelo
La Quinta Inn & Suites by Wyndham Tupelo
3 out of 5
1013 N Gloster St, Tupelo, MS
Stay at this 3-star business-friendly hotel in Tupelo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,003 reviews)
"My stay was good. Breakfast was sufficient. I do wish they made our bed when we were out, but my family enjoyed our stay."

Reviewed on Jun 13, 2025

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La Quinta Inn & Suites by Wyndham Tupelo
Holiday Inn Express Hotel & Suites Tupelo by IHG
Holiday Inn Express Hotel & Suites Tupelo by IHG
2.5 out of 5
1612 Mcclure Cove, Tupelo, MS
Book a stay at this business-friendly hotel in Tupelo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,004 reviews)
"This is the second time we have stayed here on our way to the beach. Staff is always friendly, room is always clean and the breakfast is awesome!"

Reviewed on Jun 10, 2025

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Holiday Inn Express Hotel & Suites Tupelo by IHG
Hotel Tupelo, a Wyndham Hotel
Hotel Tupelo, a Wyndham Hotel
3 out of 5
314 EAST MAIN ST, Tupelo, MS
Stay at this 3-star business-friendly hotel in Tupelo. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.6/10 Exceptional! (502 reviews)
"Great lo"

Reviewed on Jun 10, 2025

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Hotel Tupelo, a Wyndham Hotel
Best Western Plus Tupelo Inn & Suites
Best Western Plus Tupelo Inn & Suites
2.5 out of 5
3158 N Gloster Street, Tupelo, MS
Book a stay at this business-friendly hotel in Tupelo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,002 reviews)
"I stay here every time I'm near Tupelo, about 2-3x a year. I always have a great stay and will continue to come back"

Reviewed on Jun 14, 2025

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Best Western Plus Tupelo Inn & Suites
Holiday Inn Hotel & Suites Tupelo North by IHG
Holiday Inn Hotel & Suites Tupelo North by IHG
3 out of 5
923 North Gloster, Tupelo, MS
Stay at this 3-star business-friendly hotel in Tupelo. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (940 reviews)
"One elevator out of service."

Reviewed on Jun 5, 2025

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Holiday Inn Hotel & Suites Tupelo North by IHG
Tru By Hilton Tupelo
Tru By Hilton Tupelo
2.5 out of 5
1003 Landmark Blvd, Tupelo, MS
Stay at this hotel in Tupelo. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. ...
9.2/10 Wonderful! (501 reviews)
"Very comfortable & fairly priced. Easy to get on/off the interstate. Nice surroundings & area."

Reviewed on Jun 10, 2025

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Tru By Hilton Tupelo
See all 897 properties in Tupelo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Hotels With Free Airport Shuttle

Candlewood Suites Tupelo North by IHG
Candlewood Suites Tupelo North by IHG
2.5 out of 5
979 North Gloster St Street, and Mccullough Boulevard, Tupelo, MS
Book a stay at this business-friendly hotel in Tupelo. Enjoy free WiFi, free parking, and a free airport shuttle. Our guests praise the helpful staff in our ...
8.4/10 Very Good! (391 reviews)
"Hotel was very good with exception bed was too high for a dwarf to get in. Shower head you couldn’t adjust. I wish all hotels had shower wands."

Reviewed on Jun 14, 2025

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Candlewood Suites Tupelo North by IHG
Holiday Inn Hotel & Suites Tupelo North by IHG
Holiday Inn Hotel & Suites Tupelo North by IHG
3 out of 5
923 North Gloster, Tupelo, MS
Stay at this 3-star business-friendly hotel in Tupelo. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (940 reviews)
"One elevator out of service."

Reviewed on Jun 5, 2025

Get rates
Holiday Inn Hotel & Suites Tupelo North by IHG
See all 897 properties in Tupelo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.