Search for Cheap Deals on
Hotels in Defiance

Photo by Meghan Trefzger

Choose from 662 Defiance Hotel Deals

Country Inn & Suites by Radisson, Toledo South, OH
Country Inn & Suites by Radisson, Toledo South, OH
3 out of 5
9790 Clark Drive, Perrysburg, OH
  • 2 hours drive from ProMedica Defiance Regional Hospital
The price is $71 per night from Jan 26 to Jan 27
$71
includes taxes & fees
Jan 26 - Jan 27
Stay at this 3-star business-friendly hotel in Perrysburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,034 reviews)
"It was a very nice and comfortable stay! Staff was very helpful"

Reviewed on Jan 19, 2025

Country Inn & Suites by Radisson, Toledo South, OH
Hilton Garden Inn Toledo Downtown
Hilton Garden Inn Toledo Downtown
3 out of 5
101 N Summit St, Toledo, OH
  • 2 hours drive from ProMedica Defiance Regional Hospital
The price is $118 per night from Feb 2 to Feb 3
$118
includes taxes & fees
Feb 2 - Feb 3
Stay at this 3-star business-friendly hotel in Toledo. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
8.8/10 Excellent! (825 reviews)
"Excellent hotel and location."

Reviewed on Jan 19, 2025

Hilton Garden Inn Toledo Downtown
Renaissance Toledo Downtown Hotel
Renaissance Toledo Downtown Hotel
4 out of 5
444 N Summit Street, Toledo, OH
  • 2 hours drive from ProMedica Defiance Regional Hospital
The price is $147 per night from Feb 21 to Feb 22
$147
includes taxes & fees
Feb 21 - Feb 22
Book a stay at this business-friendly hotel in Toledo. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the restaurant and the bar ...
8.4/10 Very Good! (1,004 reviews)
Must stay..
"Perfect...breakfast and staff were pleasant and warm."

Reviewed on Jan 20, 2025

Renaissance Toledo Downtown Hotel
Motel 6 Toledo, OH
Motel 6 Toledo, OH
2 out of 5
5335 Heatherdowns Blvd, Toledo, OH
  • 2 hours drive from ProMedica Defiance Regional Hospital
The price is $55 per night from Feb 2 to Feb 3
$55
includes taxes & fees
Feb 2 - Feb 3
Stay at this motel in Toledo. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
5.8/10 (984 reviews)
"Nice"

Reviewed on Jan 17, 2025

Motel 6 Toledo, OH
Comfort Suites Perrysburg - Toledo South
Comfort Suites Perrysburg - Toledo South
2.5 out of 5
27450 Helen Dr, Perrysburg, OH
  • 2 hours drive from ProMedica Defiance Regional Hospital
The price is $69 per night from Jan 26 to Jan 27
$69
includes taxes & fees
Jan 26 - Jan 27
Book a stay at this business-friendly hotel in Perrysburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (924 reviews)
"Staff was friendly, room was clean."

Reviewed on Jan 18, 2025

Comfort Suites Perrysburg - Toledo South
Extended Stay America Suites Toledo Maumee
Extended Stay America Suites Toledo Maumee
2.5 out of 5
542 W. Dussel Dr, Maumee, OH
  • 2 hours drive from ProMedica Defiance Regional Hospital
The price is $78 per night from Feb 9 to Feb 10
$78
includes taxes & fees
Feb 9 - Feb 10
Book a stay at this business-friendly hotel in Maumee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8/10 Very Good! (498 reviews)
"My husband and I love this place.. we love that there is appliances if needed if you were to cook in your kitchen rooms are very affordable well worth $$😍💯"

Reviewed on Jan 14, 2025

Extended Stay America Suites Toledo Maumee
Belamere Suites Hotel
Belamere Suites Hotel
3.5 out of 5
12200 Williams Rd, Perrysburg, OH
  • 2 hours drive from ProMedica Defiance Regional Hospital
The price is $240 per night from Jan 23 to Jan 24
$240
includes taxes & fees
Jan 23 - Jan 24
Stay at this 3.5-star hotel in Perrysburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the room service in our reviews. Popular attractions ...
9.2/10 Wonderful! (100 reviews)
"Everything was beautiful relaxing can’t wait to come back"

Reviewed on Jan 11, 2025

Belamere Suites Hotel
Red Roof Inn Toledo - University
Red Roof Inn Toledo - University
2 out of 5
3530 Executive Parkway, I-475 and Exit #17 / Secor Rd, Toledo, OH
  • 2 hours drive from ProMedica Defiance Regional Hospital
The price is $60 per night from Jan 29 to Jan 30
$60
includes taxes & fees
Jan 29 - Jan 30
Stay at this hotel in Toledo. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7/10 Good! (1,000 reviews)
"Staff really nice"

Reviewed on Jan 12, 2025

Red Roof Inn Toledo - University
Red Roof Inn Toledo - Maumee
Red Roof Inn Toledo - Maumee
2 out of 5
1570 South Reynolds Road, Maumee, OH
  • 2 hours drive from ProMedica Defiance Regional Hospital
The price is $62 per night from Jan 26 to Jan 27
$62
includes taxes & fees
Jan 26 - Jan 27
Stay at this hotel in Maumee. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7/10 Good! (1,001 reviews)
"Easy parking . Quiet. Cheap plane to stay the night"

Reviewed on Jan 13, 2025

Red Roof Inn Toledo - Maumee
Courtyard by Marriott Toledo West
Courtyard by Marriott Toledo West
3 out of 5
3536 Secor Road, Toledo, OH
  • 2 hours drive from ProMedica Defiance Regional Hospital
The price is $110 per night from Feb 2 to Feb 3
$110
includes taxes & fees
Feb 2 - Feb 3
Book a stay at this business-friendly hotel in Toledo. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.6/10 Excellent! (486 reviews)
"Great room. Wonderful staff."

Reviewed on Jan 4, 2025

Courtyard by Marriott Toledo West
Hampton Inn Toledo-South/Maumee
Hampton Inn Toledo-South/Maumee
2.5 out of 5
1409 Reynolds Rd, Maumee, OH
  • 2 hours drive from ProMedica Defiance Regional Hospital
The price is $108 per night from Jan 30 to Jan 31
$108
includes taxes & fees
Jan 30 - Jan 31
Stay at this hotel in Maumee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9/10 Wonderful! (1,000 reviews)
"The staff was very friendly and helpful."

Reviewed on Jan 17, 2025

Hampton Inn Toledo-South/Maumee
Comfort Inn & Suites
Comfort Inn & Suites
2.5 out of 5
5865 Hagman Rd, Toledo, OH
  • 2 hours drive from ProMedica Defiance Regional Hospital
The price is $79 per night from Feb 7 to Feb 8
$79
includes taxes & fees
Feb 7 - Feb 8
Book a stay at this business-friendly hotel in Toledo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.8/10 Good! (877 reviews)
"Nice"

Reviewed on Jan 20, 2025

Comfort Inn & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Defiance

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Defiance hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Defiance.

Choosing the right hotel in Ohio has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Defiance’s 662 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $55. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Defiance hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Defiance. No matter your reason for visiting Defiance, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Defiance hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Defiance for as low as $55.

How many hotels are there in Defiance?

With over 662 hotels in Defiance, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $55.

How to find cheap car rentals in Defiance?

Finding a cheap car rental deal in Defiance is as easy as scoring cheap hotels in Defiance. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.