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Choose from 61 Friedheim Hotel Deals

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

3 out of 5
225 Drury Lane Jackson MO
  • 5 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.6/10 Exceptional! (1,017 reviews)
"Hands down, the best hotel by far anywhere within 500 miles!"

Reviewed on Jun 11, 2026

Drury Inn & Suites Jackson MO
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3 out of 5
3003 SOUTH OLD ORCHARD ROAD Jackson MO
  • 6 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (780 reviews)
"Air didn’t work in our room and they didn’t have another room for us and would not give us a refund"

Reviewed on Jun 7, 2026

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North

2.5 out of 5
2011 North Kingshighway Cape Girardeau MO
  • 6 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
7.2/10 Good! (757 reviews)
"The sink and tub barely drained and the air conditioner was so loud"

Reviewed on Jun 11, 2026

Quality Inn Cape Girardeau North
Days Inn by Wyndham Perryville

Days Inn by Wyndham Perryville

2 out of 5
1500 Liberty Street Perryville MO
  • 5 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Perryville Country Club and ...
6.8/10 (439 reviews)
"The first room we were given had not been cleaned; dirty towels on the floor, unmade bed. The 2nd room we were given had dirty sheets. The front desk gave us new sheets which when we went to put them on the bed were stained and when removing the dirty sheets, the mattress topper had blood on it. ..."

Reviewed on Jun 1, 2026

Days Inn by Wyndham Perryville
Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

2.5 out of 5
2520 Veterans Memorial Dr Cape Girardeau MO
  • 6 hours drive from Mississippi River
Stay at this hotel in Cape Girardeau. Enjoy free breakfast, free parking, and a fitness center. Popular attractions Cape Girardeau Conservation Nature Center ...
9.6/10 Exceptional! (135 reviews)
"The staff is amazing! We LOVE this hotel."

Reviewed on Jun 11, 2026

Tru By Hilton Cape Girardeau
Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG

2.5 out of 5
2020 Jefferson St Perryville MO
  • 5 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (593 reviews)
"Beautiful new hotel didn’t disappoint! Rey comfortable beds. Great breakfast and attentive staff keeping things filed for the best guest experience. I would definitely stop there again on my next trip through Perryville!"

Reviewed on Jun 7, 2026

Holiday Inn Express & Suites Perryville by IHG
Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville

2 out of 5
1119 Vincent Dr Perryville MO
  • 5 hours drive from Mississippi River
Book a stay at this business-friendly motel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (1,003 reviews)
"Ok on cleanliness but needed more staff cleaning breakfast room"

Reviewed on Jun 10, 2026

Super 8 by Wyndham Perryville
Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau

2.5 out of 5
2904 Old Orchard Rd Jackson MO
  • 6 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Cape Girardeau Conservation Nature ...
8.2/10 Very Good! (770 reviews)
"Hotel was no clean. Spider webs everywhere. Rooms smelled like mildew. Woke up congested because of the mildew. Do not recommend for the price you can get a much cleaner hotel with better amenities"

Reviewed on Jun 8, 2026

Comfort Suites Jackson-Cape Girardeau
The Atrium - A Boutique Hotel

The Atrium - A Boutique Hotel

2 out of 5
112 W Ste Maries St Perryville MO
  • 5 hours drive from Mississippi River
Stay at this aparthotel in Perryville. Enjoy free WiFi, free parking, and bathrobes. Popular attractions Feltz Street Park and Perryville Country Club are located ...
9.4/10 Exceptional! (3 reviews)
"Very nice clean room with comfortable bed and nice shower. Kitchenette was good with microwave and mini fridge, basic dishes. The owner was very easy to communicate with. Good location with Mary Jane’s restaurant bar next door had excellent food and nice atmosphere. My only small suggestion would ..."

Reviewed on May 3, 2026

The Atrium - A Boutique Hotel
Town House Inn

Town House Inn

2.5 out of 5
517 E Jackson Blvd Jackson MO
  • 6 hours drive from Mississippi River
Stay at this motel in Jackson. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
Town House Inn
EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel

3 out of 5
301 1st St Marble Hill MO
  • 6 hours drive from Mississippi River
Stay at this hotel in Marble Hill. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews.
9.6/10 Exceptional! (97 reviews)
"Wonderful stay!"

Reviewed on Jun 7, 2026

EC Reed's Mercantile and Hotel
Quality Inn Perryville I-55

Quality Inn Perryville I-55

2.5 out of 5
1517 S. Perryville Blvd. Perryville MO
  • 5 hours drive from Mississippi River
Stay at this hotel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Perryville Country Club and Saint Marys Lake are located ...
6.8/10 (133 reviews)
"Got in late and left early. Felt safe and clean. I appreciated the breakfast being open early on a Saturday morning."

Reviewed on May 21, 2026

Quality Inn Perryville I-55
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Friedheim

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Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Friedheim’s 61 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $76. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Friedheim hotel deals at the last minute.

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Frequently Asked Questions About Friedheim hotels

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How many hotels are there in Friedheim?

With over 61 hotels in Friedheim, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $76.

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Finding a cheap car rental deal in Friedheim is as easy as scoring cheap hotels in Friedheim. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.