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Hotels in Hillsboro

Choose from 272 Hillsboro Hotel Deals

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive Fenton MO
  • 44 min drive from Villa Antonio Winery
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,096 reviews)
Coffee!! And the breakfast. Both were fantastic! Room was clean and nice except for the heating. Didn’t get much sleep due to a very noisy heating unit. Friendly people at check in and out.

Reviewed on Feb 8, 2026

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
River City Casino & Hotel

River City Casino & Hotel

4 out of 5
777 River City Casino Blvd St. Louis MO
  • 50 min drive from Villa Antonio Winery
Book a stay at this business-friendly hotel in St. Louis. Enjoy free parking, 5 restaurants, and a casino. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,482 reviews)
The staff were very courteous and the room was clean and nice.

Reviewed on Feb 9, 2026

River City Casino & Hotel
The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
2801 Fountain Pl Wildwood MO
  • 54 min drive from Villa Antonio Winery
Book a stay at this business-friendly hotel in Wildwood. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the convenient ...
9.2/10 Wonderful! (1,628 reviews)
Excellent stay at Wildwood Hotel

Reviewed on Feb 13, 2026

The Wildwood Hotel
Best Western St. Louis-Kirkwood Route 66

Best Western St. Louis-Kirkwood Route 66

3.5 out of 5
1200 S Kirkwood Road Kirkwood MO
  • 48 min drive from Villa Antonio Winery
Book a stay at this business-friendly hotel in Kirkwood. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.2/10 Very Good! (1,415 reviews)
The breakfast was better than expected. Zoey did a great job.

Reviewed on Feb 9, 2026

Best Western St. Louis-Kirkwood Route 66
Drury Inn & Suites Southwest St. Louis

Drury Inn & Suites Southwest St. Louis

3 out of 5
5 Lambert Drury Place (I-44 & 141) Valley Park MO
  • 43 min drive from Villa Antonio Winery
Book a stay at this business-friendly hotel in Valley Park. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,008 reviews)
Condition of the hotel. Friendly staff and a great breakfast.

Reviewed on Feb 12, 2026

Drury Inn & Suites Southwest St. Louis
Best Western St. Louis Inn

Best Western St. Louis Inn

2.5 out of 5
6224 Heimos Industrial Park Dr St. Louis MO
  • 34 min drive from Villa Antonio Winery
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (1,009 reviews)
Room was clean, staff is very Pleasant.

Reviewed on Feb 10, 2026

Best Western St. Louis Inn
Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Holiday Inn Express & Suites St. Louis South - I-55 by IHG

2.5 out of 5
4250 Midamerica Lane St. Louis MO
  • 38 min drive from Villa Antonio Winery
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,002 reviews)
A clean room and a nice room, with a nice bathroom, comfortable bed, tv with a good selection of channels free, the warm chocolate chip cookies with milk at 8 pm was very nice complimentary, and complimentary breakfast was very good! Staff was very friendly and helpful! Nice swimming pool

Reviewed on Feb 7, 2026

Holiday Inn Express & Suites St. Louis South - I-55 by IHG
Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66

3 out of 5
1100 S Highway Dr Fenton MO
  • 44 min drive from Villa Antonio Winery
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.8/10 Good! (1,135 reviews)
Clean place in friendly service

Reviewed on Feb 6, 2026

Wingate by Wyndham St. Louis/Fenton Route 66
Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold

2.5 out of 5
1201 Drury Ln Arnold MO
  • 30 min drive from Villa Antonio Winery
Book a stay at this business-friendly hotel in Arnold. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,001 reviews)
Rooms were super clean. Refrigerator worked which was great. Friendly staff and marvelous free breakfast. We will recommend.

Reviewed on Jan 28, 2026

Pear Tree Inn St. Louis Arnold
La Quinta Inn & Suites by Wyndham St Louis Route 66

La Quinta Inn & Suites by Wyndham St Louis Route 66

3 out of 5
1580 S Kirkwood Rd St. Louis MO
  • 47 min drive from Villa Antonio Winery
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the ...
8/10 Very Good! (1,008 reviews)
The staff is a 10/10

Reviewed on Feb 5, 2026

La Quinta Inn & Suites by Wyndham St Louis Route 66
Holiday Inn St. Louis West Six Flags by IHG

Holiday Inn St. Louis West Six Flags by IHG

3 out of 5
4901 Six Flags Rd Eureka MO
  • 47 min drive from Villa Antonio Winery
Book a stay at this family-friendly hotel in Eureka. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.8/10 Excellent! (1,000 reviews)
The room was rather on the older side, but the Holidome was very cool. The lobby was very cool too. Staff very nice.

Reviewed on Jan 28, 2026

Holiday Inn St. Louis West Six Flags by IHG
Americas Best Value Inn St. Louis South

Americas Best Value Inn St. Louis South

2.5 out of 5
6602 S Lindbergh Blvd St. Louis MO
  • 43 min drive from Villa Antonio Winery
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Grant's Farm and Ulysses S. ...
5.4/10 (1,001 reviews)
The guy that works nights is awesome and so nice. The rooms could be cleaner but for the price no biggie.

Reviewed on Jan 20, 2026

Americas Best Value Inn St. Louis South
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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