Hotels Near
Main South

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Featured Main South Hotels

Sonesta Select Boston Milford

Sonesta Select Boston Milford

3 out of 5
10 Fortune Blvd Milford MA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Milford. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8/10 Very Good! (1,006 reviews)
Very quiet, and clean

Reviewed on Nov 20, 2025

Sonesta Select Boston Milford
DoubleTree by Hilton Hotel Boston - Westborough

DoubleTree by Hilton Hotel Boston - Westborough

4 out of 5
5400 Computer Dr Westborough MA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Westborough. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,009 reviews)
Front desk was extremely accommodating to my sudden flight changes and afforded me a much needed late checkout. And yes, the breakfast was fantastic. I only recommending adding another hot sauce like cholula or salsa!

Reviewed on Nov 19, 2025

DoubleTree by Hilton Hotel Boston - Westborough
Wellsworth Hotel

Wellsworth Hotel

3 out of 5
14 Mechanic St Southbridge MA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Southbridge. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the pool and the helpful staff ...
9/10 Wonderful! (1,352 reviews)
Staff was super friendly

Reviewed on Nov 27, 2025

Wellsworth Hotel
Hilton Garden Inn Worcester

Hilton Garden Inn Worcester

3 out of 5
35 Major Taylor Boulevard Worcester MA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Worcester. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
7.8/10 Good! (1,015 reviews)
Staff was great - quick and helpful. HOWEVER, kind of disappointed there were no drinking cups outside of paper coffee cups.

Reviewed on Nov 30, 2025

Hilton Garden Inn Worcester
Courtyard by Marriott Boston Marlborough

Courtyard by Marriott Boston Marlborough

3 out of 5
75 Felton St Marlborough MA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Marlborough. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,004 reviews)
Clean and nice facilities. Great lobby area

Reviewed on Nov 28, 2025

Courtyard by Marriott Boston Marlborough
Motel 6 Framingham, MA - Boston West

Motel 6 Framingham, MA - Boston West

2 out of 5
1668 Worcester Rd Framingham MA
Fully refundable
Stay at this motel in Framingham. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
6.6/10 (1,090 reviews)
Staff is awesome and rooms are very spacious

Reviewed on Nov 27, 2025

Motel 6 Framingham, MA - Boston West
Publick House Historic Inn and Country Motor Lodge

Publick House Historic Inn and Country Motor Lodge

2.5 out of 5
277 Main Street (RT 131) Sturbridge MA
Fully refundableReserve now, pay when you stay
Book a stay at this spa resort in Sturbridge. Enjoy free parking, an outdoor pool, and a full-service spa. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,569 reviews)
Excellent hotel, stay here often, rooms clean, an modern, staff very friendly an delicious food at bakery an restaurant

Reviewed on Nov 29, 2025

Publick House Historic Inn and Country Motor Lodge
Best Western Royal Plaza Hotel & Trade Center

Best Western Royal Plaza Hotel & Trade Center

3 out of 5
181 Boston Post Rd W Marlborough MA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Marlborough. Enjoy free breakfast, free parking, and 2 restaurants. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (1,018 reviews)
Very satisfied with my stay. Breakfast was great and the staff was nice, friendly and informative.

Reviewed on Nov 29, 2025

Best Western Royal Plaza Hotel & Trade Center
Comfort Inn Auburn - Worcester

Comfort Inn Auburn - Worcester

2.5 out of 5
426 Southbridge St Auburn MA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Auburn. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.6/10 Good! (1,012 reviews)
The food choices for the morning breakfast was amazing. Probably almost anything you would want to eat. Coffee, tea and hot chocolate all day long too.

Reviewed on Nov 25, 2025

Comfort Inn Auburn - Worcester
Red Roof Inn Boston - Southborough/ Worcester

Red Roof Inn Boston - Southborough/ Worcester

2 out of 5
367 Turnpike Rd Southborough MA
Fully refundableReserve now, pay when you stay
Stay at this hotel in Southborough. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7/10 Good! (1,001 reviews)
No car for me but did look like there was plenty of parking for people.

Reviewed on Oct 31, 2025

Red Roof Inn Boston - Southborough/ Worcester
Embassy Suites by Hilton Boston Marlborough

Embassy Suites by Hilton Boston Marlborough

3.5 out of 5
123 Boston Post Rd W Marlborough MA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Marlborough. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,011 reviews)
Comfortable, convenient

Reviewed on Nov 29, 2025

Embassy Suites by Hilton Boston Marlborough
DoubleTree by Hilton Boston - Milford

DoubleTree by Hilton Boston - Milford

4 out of 5
11 Beaver Street Milford MA
Fully refundableReserve now, pay when you stay
Stay at this hotel in Milford. Enjoy free WiFi, free parking, and 3 restaurants. Our guests praise the helpful staff in our reviews. Popular attractions Vietnam ...
8.4/10 Very Good! (979 reviews)
Clean room

Reviewed on Nov 3, 2025

DoubleTree by Hilton Boston - Milford
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Main South

Worcester is a city that has a lot going on, but you have your sights set on Main South. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Main South has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Main South hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Worcester so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Main South underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Main South city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Main South cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Main South at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $85
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Main South hotel you want, book it, and never look back. Because your great escape is ahead of you.