Hotels Near
Main South

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Featured Main South Hotels

Motel 6 Framingham, MA - Boston West

Motel 6 Framingham, MA - Boston West

2 out of 5
1668 Worcester Rd, Framingham, MA
Fully refundable
Stay at this motel in Framingham. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
6.6/10 (1,083 reviews)
Overall very good for the price

Reviewed on Nov 3, 2025

Motel 6 Framingham, MA - Boston West
DoubleTree by Hilton Hotel Boston - Westborough

DoubleTree by Hilton Hotel Boston - Westborough

4 out of 5
5400 Computer Dr, Westborough, MA
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Westborough. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,007 reviews)
Everything at this hotel was perfect.It really was the only complaint I have is.The bathroom could have been cleaner.

Reviewed on Nov 9, 2025

DoubleTree by Hilton Hotel Boston - Westborough
Courtyard by Marriott Boston Marlborough

Courtyard by Marriott Boston Marlborough

3 out of 5
75 Felton St, Marlborough, MA
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Marlborough. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,002 reviews)
Spotless rooms! Alot of towels..was very 😁

Reviewed on Nov 9, 2025

Courtyard by Marriott Boston Marlborough
Publick House Historic Inn and Country Motor Lodge

Publick House Historic Inn and Country Motor Lodge

2.5 out of 5
277 Main Street (RT 131), Sturbridge, MA
Fully refundableReserve now, pay when you stay
Book a stay at this spa resort in Sturbridge. Enjoy free parking, an outdoor pool, and a full-service spa. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,533 reviews)
The room was spotless and the staff were courteous.

Reviewed on Nov 3, 2025

Publick House Historic Inn and Country Motor Lodge
Wellsworth Hotel

Wellsworth Hotel

3 out of 5
14 Mechanic St, Southbridge, MA
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Southbridge. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the pool and the helpful staff ...
9/10 Wonderful! (1,335 reviews)
The place was awesome! Very unique, clean, quiet area! Would go back in a heartbeat.

Reviewed on Nov 10, 2025

Wellsworth Hotel
Sonesta Select Boston Milford

Sonesta Select Boston Milford

3 out of 5
10 Fortune Blvd, Milford, MA
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Milford. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...
8.2/10 Very Good! (1,009 reviews)
Room was clean one of the shampoo bottles fell off the wall before I was there other than that the room was spotless only downfall I had was I went there for some peace and quiet and the walls are very thin so I had to listen to kids screaming all night

Reviewed on Nov 9, 2025

Sonesta Select Boston Milford
Best Western Royal Plaza Hotel & Trade Center

Best Western Royal Plaza Hotel & Trade Center

3 out of 5
181 Boston Post Rd W, Marlborough, MA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Marlborough. Enjoy free breakfast, free parking, and 2 restaurants. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (1,000 reviews)
Quick easy check-in, clean room and delicious breakfast.

Reviewed on Nov 9, 2025

Best Western Royal Plaza Hotel & Trade Center
La Quinta Inn by Wyndham Auburn Worcester

La Quinta Inn by Wyndham Auburn Worcester

3 out of 5
446 Southbridge St, Auburn, MA
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Auburn. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
6.8/10 (1,019 reviews)
Yes

Reviewed on Nov 5, 2025

La Quinta Inn by Wyndham Auburn Worcester
Hilton Garden Inn Worcester

Hilton Garden Inn Worcester

3 out of 5
35 Major Taylor Boulevard, Worcester, MA
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Worcester. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
7.8/10 Good! (1,002 reviews)
Great room, clean and comfortable beds!

Reviewed on Nov 2, 2025

Hilton Garden Inn Worcester
Comfort Inn Auburn - Worcester

Comfort Inn Auburn - Worcester

2.5 out of 5
426 Southbridge St, Auburn, MA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Auburn. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.6/10 Good! (1,001 reviews)
Everything was great

Reviewed on Nov 4, 2025

Comfort Inn Auburn - Worcester
Hampton Inn Boston/Marlborough

Hampton Inn Boston/Marlborough

2.5 out of 5
277 Boston Post Rd West, Marlborough, MA
Fully refundableReserve now, pay when you stay
Stay at this hotel in Marlborough. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (1,002 reviews)
Breakfast was horrendous. I had oatmeal and I wanted to put some brown sugar on it but a jackhammer couldn’t break it up

Reviewed on Nov 5, 2025

Hampton Inn Boston/Marlborough
Hyatt Place Marlborough/Apex Center

Hyatt Place Marlborough/Apex Center

3 out of 5
169 Apex Drive, Marlborough, MA
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Marlborough. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,001 reviews)
Nice properry

Reviewed on Nov 5, 2025

Hyatt Place Marlborough/Apex Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Main South

Worcester is a city that has a lot going on, but you have your sights set on Main South. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Main South has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Main South hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Worcester so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Main South underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Main South city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Main South cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Main South at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $87
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Main South hotel you want, book it, and never look back. Because your great escape is ahead of you.