Hotels Near
Main South

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Featured Main South Hotels

Motel 6 Framingham, MA - Boston West
Motel 6 Framingham, MA - Boston West
2 out of 5
1668 Worcester Rd, Framingham, MA
Fully refundable
Stay at this motel in Framingham. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
6.6/10 (1,005 reviews)
"Good customer service"

Reviewed on Apr 3, 2025

Motel 6 Framingham, MA - Boston West
DoubleTree by Hilton Hotel Boston - Westborough
DoubleTree by Hilton Hotel Boston - Westborough
4 out of 5
5400 Computer Dr, Westborough, MA
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Westborough. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,000 reviews)
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Reviewed on Mar 31, 2025

DoubleTree by Hilton Hotel Boston - Westborough
Wellsworth Hotel
Wellsworth Hotel
3 out of 5
14 Mechanic St, Southbridge, MA
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Southbridge. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the pool and the helpful staff ...
9/10 Wonderful! (1,142 reviews)
"close to college we visited"

Reviewed on Apr 3, 2025

Wellsworth Hotel
Comfort Inn Auburn - Worcester
Comfort Inn Auburn - Worcester
2.5 out of 5
426 Southbridge St, Auburn, MA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Auburn. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.6/10 Good! (923 reviews)
"NA"

Reviewed on Mar 27, 2025

Comfort Inn Auburn - Worcester
Embassy Suites by Hilton Boston Marlborough
Embassy Suites by Hilton Boston Marlborough
3.5 out of 5
123 Boston Post Rd W, Marlborough, MA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Marlborough. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (932 reviews)
"Awesome"

Reviewed on Mar 28, 2025

Embassy Suites by Hilton Boston Marlborough
Best Western Royal Plaza Hotel & Trade Center
Best Western Royal Plaza Hotel & Trade Center
3 out of 5
181 Boston Post Rd W, Marlborough, MA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Marlborough. Enjoy free breakfast, free parking, and 2 restaurants. Our guests praise the breakfast and the helpful ...
7.6/10 Good! (1,002 reviews)
"Amazing service"

Reviewed on Apr 3, 2025

Best Western Royal Plaza Hotel & Trade Center
Hyatt Place Marlborough/Apex Center
Hyatt Place Marlborough/Apex Center
3 out of 5
169 Apex Drive, Marlborough, MA
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Marlborough. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,002 reviews)
"Nice area, clean room, comfortable. High recommendation to stay"

Reviewed on Mar 30, 2025

Hyatt Place Marlborough/Apex Center
Hilton Garden Inn Worcester
Hilton Garden Inn Worcester
3 out of 5
35 Major Taylor Boulevard, Worcester, MA
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Worcester. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
7.8/10 Good! (1,000 reviews)
"Very nice and helpful staff. Room was clean and the bed was comfortable"

Reviewed on Mar 31, 2025

Hilton Garden Inn Worcester
Extended Stay America Suites Boston Westborough Computer Dr
Extended Stay America Suites Boston Westborough Computer Dr
2.5 out of 5
1800 Computer Dr, Westborough, MA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Westborough. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
6.2/10 (812 reviews)
"We were absolutely thrilled with this property. The premises were clean, accessible and safe. The staff was exceptionally helpful and very friendly [uncommon nowadays for customer service]. Room 105 for almost 2 months greatly appreciates this staff. Thank you greatly. Although we are happy to be ..."

Reviewed on Apr 3, 2025

Extended Stay America Suites Boston Westborough Computer Dr
Hampton Inn & Suites Worcester
Hampton Inn & Suites Worcester
2.5 out of 5
65 Prescott St, Worcester, MA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Worcester. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,000 reviews)
"Parking was easy and convenient, front desk staff was very friendly and the room was nicely laid out and comfortable."

Reviewed on Mar 31, 2025

Hampton Inn & Suites Worcester
Publick House Historic Inn and Country Motor Lodge
Publick House Historic Inn and Country Motor Lodge
2.5 out of 5
277 Main Street (RT 131), Sturbridge, MA
Fully refundableReserve now, pay when you stay
Book a stay at this spa resort in Sturbridge. Enjoy free parking, an outdoor pool, and a full-service spa. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,376 reviews)
"The rooms are clean and very well kept. The staff are very pleasant and professional. I was there for a two night stay for an on-site wedding. The only area of opportunity for me would be the room’s climate control. It was rainy & cold, even after adjusting the thermostat the room remain colder that ..."

Reviewed on Mar 31, 2025

Publick House Historic Inn and Country Motor Lodge
Hampton Inn Boston/Marlborough
Hampton Inn Boston/Marlborough
2.5 out of 5
277 Boston Post Rd West, Marlborough, MA
Fully refundableReserve now, pay when you stay
Stay at this hotel in Marlborough. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (998 reviews)
"Check in was smooth and easy. Front desk staff was welcoming and friendly!"

Reviewed on Mar 30, 2025

Hampton Inn Boston/Marlborough
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Main South

Worcester is a city that has a lot going on, but you have your sights set on Main South. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Main South has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Main South hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Worcester so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Main South underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Main South city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Main South cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Main South at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $86
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Main South hotel you want, book it, and never look back. Because your great escape is ahead of you.