Search for Cheap Deals on
Hotels in Matlacha

Choose from 14670 Matlacha Hotel Deals

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

2.5 out of 5
1538 Cape Coral Pkwy E Cape Coral FL
  • 12 min drive from Matlacha Bridge
Book a stay at this business-friendly hotel in Cape Coral. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,286 reviews)
Super clean hotel and property. Comfortable beds. Buffet breakfast was fresh and plentiful .Fresh ground coffee was a plus!

Reviewed on Mar 7, 2026

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
  • 30 min drive from Matlacha Bridge
Book a stay at this beach hotel in Fort Myers Beach. Enjoy free WiFi, a full-service spa, and 4 restaurants. Our guests praise the pool and the helpful staff ...
9/10 Wonderful! (1,929 reviews)
Great resort, nice clean rooms, staff is very friendly and the pool and food are excellent.

Reviewed on Mar 8, 2026

Margaritaville Beach Resort Fort Myers
Sanibel Island Beach Resort

Sanibel Island Beach Resort

3 out of 5
1231 Middle Gulf Dr Sanibel FL
  • 33 min drive from Matlacha Bridge
Book a stay at this beach hotel in Sanibel. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the pool and the restaurant in our reviews. ...
9.2/10 Wonderful! (1,665 reviews)
Clean room, easy walk straight out to beach, tiki bar best around and pool water warm and relaxing

Reviewed on Mar 8, 2026

Sanibel Island Beach Resort
Baymont by Wyndham Fort Myers Central

Baymont by Wyndham Fort Myers Central

2.5 out of 5
4850 S Cleveland Ave Fort Myers FL
  • 8 min drive from Matlacha Bridge
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (1,036 reviews)
We booked because of free breakfast and pool, but close to baseball games. The pool was closed, breakfast was VERY limited. Our room was dirty when we arrived, our feet left black stuff in the shower. The towels were like paper towels and you never knew how many you were getting. Ice was not available ...

Reviewed on Mar 8, 2026

Baymont by Wyndham Fort Myers Central
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd Fort Myers Beach FL
  • 31 min drive from Matlacha Bridge
Book a stay at this beach hotel in Fort Myers Beach. Enjoy free WiFi, an outdoor pool, and a beach locale. Popular attractions Key West Express and Crescent ...
9/10 Wonderful! (1,293 reviews)
.

Reviewed on Mar 8, 2026

Lani Kai Beachfront Resort
Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers

3 out of 5
12600 University Dr Fort Myers FL
  • 13 min drive from Matlacha Bridge
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.8/10 Excellent! (1,014 reviews)
Clean, well kept.

Reviewed on Mar 8, 2026

Hilton Garden Inn Ft Myers
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

4 out of 5
17260 Harbour Pointe Dr Fort Myers FL
  • 24 min drive from Matlacha Bridge
Book a stay at this spa resort in Fort Myers. Enjoy 3 outdoor pools, a full-service spa, and 4 restaurants. Our guests praise the helpful staff and the property ...
8.4/10 Very Good! (1,011 reviews)
Beautiful hotel with plenty of amenities. We had an ocean front view watching beautiful sunsets over the Gulf over Sanibel Island!

Reviewed on Mar 8, 2026

Marriott Sanibel Harbour Resort & Spa
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

2.5 out of 5
11171 Summerlin Square Drive Fort Myers Beach FL
  • 24 min drive from Matlacha Bridge
Book a stay at this business-friendly hotel in Fort Myers Beach. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,010 reviews)
Everything was just as it should be. Clean. Comfortable Plenty of breakfast. Only thing that would make it better is if they had loaner beach chairs and umbrellas.

Reviewed on Mar 8, 2026

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
DiamondHead Beach Resort

DiamondHead Beach Resort

3.5 out of 5
2000 Estero Blvd Fort Myers Beach FL
  • 31 min drive from Matlacha Bridge
Book a stay at this beach resort in Fort Myers Beach. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the pool and the helpful staff in ...
9.2/10 Wonderful! (1,078 reviews)
Clean, perfect room for our family. Best vacation yet.

Reviewed on Mar 7, 2026

DiamondHead Beach Resort
Hyatt Place Fort Myers/at The Forum

Hyatt Place Fort Myers/at The Forum

3 out of 5
2600 Champion Ring Rd Fort Myers FL
  • 26 min walk from Matlacha Bridge
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,011 reviews)
Gym was well equipped and the breakfast had such a wide variety all three kids found stuff they loved.

Reviewed on Mar 8, 2026

Hyatt Place Fort Myers/at The Forum
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

2 out of 5
10150 Daniels Pkwy Fort Myers FL
  • 15 min drive from Matlacha Bridge
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the clean rooms ...
8/10 Very Good! (1,624 reviews)
Nice roction

Reviewed on Mar 8, 2026

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
Courtyard by Marriott Fort Myers Cape Coral

Courtyard by Marriott Fort Myers Cape Coral

3 out of 5
4455 Metro Pkwy Fort Myers FL
  • 7 min drive from Matlacha Bridge
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.2/10 Very Good! (1,007 reviews)
Super clean room! The staff was all so friendly and we loved our stay

Reviewed on Mar 6, 2026

Courtyard by Marriott Fort Myers Cape Coral
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Matlacha

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Matlacha hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Matlacha.

Choosing the right hotel in Florida has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Matlacha’s 14,670 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $95. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Matlacha hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Matlacha. No matter your reason for visiting Matlacha, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Matlacha hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Matlacha for as low as $95.

How many hotels are there in Matlacha?

With over 14,670 hotels in Matlacha, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $95.

How to find cheap car rentals in Matlacha?

Finding a cheap car rental deal in Matlacha is as easy as scoring cheap hotels in Matlacha. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.