Search for Cheap Deals on
Hotels in Saint James City

Choose from 15889 Saint James City Hotel Deals

Off the Charts Inn & Out Island Resort

Off the Charts Inn & Out Island Resort

2.5 out of 5
2938 Sanibel Blvd Saint James City FL
  • 9 min drive from Key West Express
Stay at this motel in Saint James City. Enjoy free WiFi, free parking, and free grocery shopping service. Our guests praise the helpful staff in our reviews. ...
9.6/10 Exceptional! (150 reviews)
Nice quiet clean room with fully equipped kitchen. Great for a small getaway. We could walk right out to the canal and watch the manatees and dolphins swim. Also saw an eagle flying over as well as several other species of birds. If you have a boat you can dock outside your door in the canal or rent ...

Reviewed on Jan 7, 2026

Off the Charts Inn & Out Island Resort
Sanibel Island Beach Resort

Sanibel Island Beach Resort

3 out of 5
1231 Middle Gulf Dr Sanibel FL
  • 6 min drive from Key West Express
Book a stay at this beach hotel in Sanibel. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the pool and the restaurant in our reviews. ...
9/10 Wonderful! (1,548 reviews)
Good clean room. Friendly helpful staff

Reviewed on Jan 20, 2026

Sanibel Island Beach Resort
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd Fort Myers Beach FL
  • 10 min walk from Key West Express
Book a stay at this beach hotel in Fort Myers Beach. Enjoy free WiFi, an outdoor pool, and a beach locale. Popular attractions Key West Express and Crescent ...
8.8/10 Excellent! (1,137 reviews)
Didn't eat breakfast room was clean

Reviewed on Jan 20, 2026

Lani Kai Beachfront Resort
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
  • 9 min walk from Key West Express
Book a stay at this beach hotel in Fort Myers Beach. Enjoy free WiFi, a full-service spa, and 4 restaurants. Our guests praise the pool and the helpful staff ...
8.8/10 Excellent! (1,815 reviews)
I do not know why they don’t have a basic microwave in every room! Also the water pressure in our room was horrible i froze in the shower! No chairs on Wednesday for the pool but i guess they have senior citizen day! I won’t stay here again! Also you must pay for the 35 valet parking! I hate places ...

Reviewed on Jan 22, 2026

Margaritaville Beach Resort Fort Myers
Baymont by Wyndham Fort Myers Central

Baymont by Wyndham Fort Myers Central

2.5 out of 5
4850 S Cleveland Ave Fort Myers FL
  • 22 min drive from Key West Express
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.6/10 (1,004 reviews)
Gray service

Reviewed on Jan 25, 2026

Baymont by Wyndham Fort Myers Central
Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers

3 out of 5
12600 University Dr Fort Myers FL
  • 17 min drive from Key West Express
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.6/10 Excellent! (1,008 reviews)
The staff and room were great. I would absolutely stay here again.

Reviewed on Jan 24, 2026

Hilton Garden Inn Ft Myers
Hyatt Place Fort Myers/at The Forum

Hyatt Place Fort Myers/at The Forum

3 out of 5
2600 Champion Ring Rd Fort Myers FL
  • 29 min drive from Key West Express
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,007 reviews)
super limpia y confortable

Reviewed on Jan 19, 2026

Hyatt Place Fort Myers/at The Forum
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

2 out of 5
10150 Daniels Pkwy Fort Myers FL
  • 16 min drive from Key West Express
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the clean rooms ...
8/10 Very Good! (1,545 reviews)
Great

Reviewed on Jan 21, 2026

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
DiamondHead Beach Resort

DiamondHead Beach Resort

3.5 out of 5
2000 Estero Blvd Fort Myers Beach FL
  • 12 min walk from Key West Express
Book a stay at this beach resort in Fort Myers Beach. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the pool and the helpful staff in ...
9/10 Wonderful! (1,037 reviews)
Very clean, nice pool and amenities, especially on the beach. NO BREAKFAST OPTIONS, so bring your own or plan to go out. Not sure why they don’t offer continental or buffet??

Reviewed on Jan 22, 2026

DiamondHead Beach Resort
Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina

4 out of 5
275 Estero Blvd Fort Myers Beach FL
  • 7 min walk from Key West Express
Book a stay at this beach resort in Fort Myers Beach. Enjoy free breakfast, 3 outdoor pools, and 3 restaurants. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (1,241 reviews)
Room was wonderful with good view, it was clean and well kept by the cleaning staff. Amenities were great and it was in an excellent location. Restaurants are all convenient and there is plenty of seating as well as good entertainment that include a live singer over the weekends. Free breakfast it ...

Reviewed on Jan 21, 2026

Pink Shell Beach Resort and Marina
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

4 out of 5
17260 Harbour Pointe Dr Fort Myers FL
  • 6 min drive from Key West Express
Book a stay at this spa resort in Fort Myers. Enjoy 3 outdoor pools, a full-service spa, and 4 restaurants. Our guests praise the helpful staff and the property ...
8.4/10 Very Good! (1,004 reviews)
Resort was very nice. Gym needs more cleaning. Bar staff very gracious. Front desk staff courteous. Valet-all staff outstanding!!

Reviewed on Jan 25, 2026

Marriott Sanibel Harbour Resort & Spa
Hyatt Vacation Club at Coconut Cove, Bonita Springs

Hyatt Vacation Club at Coconut Cove, Bonita Springs

4 out of 5
11800 Coconut Cove Drive Bonita Springs FL
  • 10 min drive from Key West Express
Book a stay at this golf aparthotel in Bonita Springs. Enjoy free WiFi, free parking, and 3 outdoor pools. Popular attractions Coconut Point Mall and Bonita ...
9/10 Wonderful! (769 reviews)
Great place to stay!

Reviewed on Jan 19, 2026

Hyatt Vacation Club at Coconut Cove, Bonita Springs
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Saint James City

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Saint James City hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Saint James City.

Choosing the right hotel in Florida has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Saint James City’s 15,889 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $100. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Saint James City hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Saint James City. No matter your reason for visiting Saint James City, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Saint James City hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Saint James City for as low as $100.

How many hotels are there in Saint James City?

With over 15,889 hotels in Saint James City, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $100.

How to find cheap car rentals in Saint James City?

Finding a cheap car rental deal in Saint James City is as easy as scoring cheap hotels in Saint James City. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.