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Hotels in Saint James City

Choose from 16113 Saint James City Hotel Deals

Off the Charts Inn & Out Island Resort

Off the Charts Inn & Out Island Resort

2.5 out of 5
2938 Sanibel Blvd Saint James City FL
  • 9 min drive from Key West Express
Stay at this motel in Saint James City. Enjoy free WiFi, free parking, and free grocery shopping service. Our guests praise the helpful staff in our reviews. ...
9.6/10 Exceptional! (158 reviews)
second floor with the screened in porch was fabulous! Loved the hanging chair and we had a full view of all of the manatee's outback! Perfectly located, will stay here again for sure!~

Reviewed on Apr 17, 2026

Off the Charts Inn & Out Island Resort
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
  • 9 min walk from Key West Express
Book a stay at this beach hotel in Fort Myers Beach. Enjoy free WiFi, a full-service spa, and 4 restaurants. Our guests praise the pool and the helpful staff ...
9/10 Wonderful! (2,050 reviews)
Everything was super good. I am very happy with my stay. Thank you.

Reviewed on Apr 27, 2026

Margaritaville Beach Resort Fort Myers
Sanibel Island Beach Resort

Sanibel Island Beach Resort

3 out of 5
1231 Middle Gulf Dr Sanibel FL
  • 6 min drive from Key West Express
Book a stay at this beach hotel in Sanibel. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the pool and the restaurant in our reviews. ...
9.2/10 Wonderful! (1,833 reviews)
Staff was friendly and accommodating!

Reviewed on Apr 27, 2026

Sanibel Island Beach Resort
Baymont by Wyndham Fort Myers Central

Baymont by Wyndham Fort Myers Central

2.5 out of 5
4850 S Cleveland Ave Fort Myers FL
  • 22 min drive from Key West Express
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (1,047 reviews)
A very bad experience. When I checked in, the woman at the front desk seemed like she had no desire to work she didn’t even say good evening, and her explanation of where the room was located was given with a poor attitude. The room had a strong musty smell, the sheets had cigarette burn marks, and ...

Reviewed on Apr 27, 2026

Baymont by Wyndham Fort Myers Central
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

2.5 out of 5
1538 Cape Coral Pkwy E Cape Coral FL
  • 17 min drive from Key West Express
Book a stay at this business-friendly hotel in Cape Coral. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,428 reviews)
Amazing place to stay away from home. If you need anything justa ask the front desk and they will bring to you.

Reviewed on Apr 27, 2026

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd Fort Myers Beach FL
  • 10 min walk from Key West Express
Book a stay at this beach hotel in Fort Myers Beach. Enjoy free WiFi, 3 restaurants, and a beach locale. Popular attractions Key West Express and Estero Boulevard ...
9/10 Wonderful! (1,435 reviews)
Everything about this place is top notch! Staff is very professional and accommodating! Food is delicious and the rooms are very comfortable and clean. Housekeeping was exceptional! A must visit!!

Reviewed on Apr 27, 2026

Lani Kai Beachfront Resort
Trianon Bonita Bay

Trianon Bonita Bay

3.5 out of 5
3401 Bay Commons Dr Bonita Springs FL
  • 20 min drive from Key West Express
Book a stay at this family-friendly hotel in Bonita Springs. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
9.2/10 Wonderful! (1,776 reviews)
This I wonderful hotel. Our 3rd time staying there. The rooms are well appointed and clean. The pool is very nice and heated. The hot tub is so nice too. There is a restaurant on the grounds called Lake House Bar and Grill. Everything we have eaten there is so good. The grounds surrounding the hotel ...

Reviewed on Apr 27, 2026

Trianon Bonita Bay
Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina

4 out of 5
275 Estero Blvd Fort Myers Beach FL
  • 7 min walk from Key West Express
Book a stay at this beach resort in Fort Myers Beach. Enjoy free breakfast, 3 outdoor pools, and 3 restaurants. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (1,332 reviews)
Very clean room, staff was very helpful and delightful. Free breakfast is very good deal and a lot of food. The views from our room which included the octopool and the Gulf were stunning and amazing. We loved that the balconies are screening in top to bottom for safety too. 100% going back!!!

Reviewed on Apr 27, 2026

Pink Shell Beach Resort and Marina
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

4 out of 5
17260 Harbour Pointe Dr Fort Myers FL
  • 6 min drive from Key West Express
Book a stay at this spa resort in Fort Myers. Enjoy 3 outdoor pools, a full-service spa, and 4 restaurants. Our guests praise the helpful staff and the property ...
8.4/10 Very Good! (1,008 reviews)
Clean rooms, polite staff and great breakfast

Reviewed on Apr 27, 2026

Marriott Sanibel Harbour Resort & Spa
Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers

3 out of 5
12600 University Dr Fort Myers FL
  • 17 min drive from Key West Express
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.8/10 Excellent! (1,007 reviews)
Beautiful property! Wonderful breakfast. Had an issue 1st night with odor from drain. Sink. Took care of it right away next morning! Very impressed...

Reviewed on Apr 27, 2026

Hilton Garden Inn Ft Myers
Holiday Inn Express & Suites Fort Myers Airport by IHG

Holiday Inn Express & Suites Fort Myers Airport by IHG

2.5 out of 5
14567 GLOBAL PARKWAY Fort Myers FL
  • 13 min drive from Key West Express
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.6/10 Exceptional! (1,010 reviews)
None at this time

Reviewed on Apr 27, 2026

Holiday Inn Express & Suites Fort Myers Airport by IHG
Doubletree by Hilton Fort Myers at Bell Tower Shops

Doubletree by Hilton Fort Myers at Bell Tower Shops

4 out of 5
13051 Bell Tower Drive Fort Myers FL
  • 16 min drive from Key West Express
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,088 reviews)
This hotel is well maintained and is conveniently located to shopping and restaurants within walking distance. This will be my go-to hotel in Fort Myers.

Reviewed on Apr 28, 2026

Doubletree by Hilton Fort Myers at Bell Tower Shops
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Saint James City

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