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Hotels in Saint James City

Choose from 16113 Saint James City Hotel Deals

Off the Charts Inn & Out Island Resort

Off the Charts Inn & Out Island Resort

2.5 out of 5
2938 Sanibel Blvd Saint James City FL
  • 9 min drive from Key West Express
Stay at this motel in Saint James City. Enjoy free WiFi, free parking, and free grocery shopping service. Our guests praise the helpful staff in our reviews. ...
9.6/10 Exceptional! (158 reviews)
second floor with the screened in porch was fabulous! Loved the hanging chair and we had a full view of all of the manatee's outback! Perfectly located, will stay here again for sure!~

Reviewed on Apr 17, 2026

Off the Charts Inn & Out Island Resort
Baymont by Wyndham Fort Myers Central

Baymont by Wyndham Fort Myers Central

2.5 out of 5
4850 S Cleveland Ave Fort Myers FL
  • 22 min drive from Key West Express
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (1,046 reviews)
A very bad experience. When I checked in, the woman at the front desk seemed like she had no desire to work she didn’t even say good evening, and her explanation of where the room was located was given with a poor attitude. The room had a strong musty smell, the sheets had cigarette burn marks, and ...

Reviewed on Apr 27, 2026

Baymont by Wyndham Fort Myers Central
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
  • 9 min walk from Key West Express
Book a stay at this beach hotel in Fort Myers Beach. Enjoy free WiFi, a full-service spa, and 4 restaurants. Our guests praise the pool and the helpful staff ...
9/10 Wonderful! (2,046 reviews)
We came in early afternoon and the pool was packed. Nowhere to sit. Went to La De Da for lunch and it was delicious. Loved our room love the access to the bridge, coffee, shop, and restaurant downstairs. Looking forward to coming back.

Reviewed on Apr 27, 2026

Margaritaville Beach Resort Fort Myers
Sanibel Island Beach Resort

Sanibel Island Beach Resort

3 out of 5
1231 Middle Gulf Dr Sanibel FL
  • 6 min drive from Key West Express
Book a stay at this beach hotel in Sanibel. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the pool and the restaurant in our reviews. ...
9.2/10 Wonderful! (1,827 reviews)
Nice property’s ,respectful employees overall good experience

Reviewed on Apr 26, 2026

Sanibel Island Beach Resort
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

2.5 out of 5
1538 Cape Coral Pkwy E Cape Coral FL
  • 17 min drive from Key West Express
Book a stay at this business-friendly hotel in Cape Coral. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,424 reviews)
The property was well-maintained, with a relaxing pool area and an updated room. There were also various breakfast options available. The friendly and welcoming staff made the stay enjoyable.

Reviewed on Apr 26, 2026

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd Fort Myers Beach FL
  • 10 min walk from Key West Express
Book a stay at this beach hotel in Fort Myers Beach. Enjoy free WiFi, 3 restaurants, and a beach locale. Popular attractions Key West Express and Estero Boulevard ...
9/10 Wonderful! (1,433 reviews)
Great beach view!

Reviewed on Apr 27, 2026

Lani Kai Beachfront Resort
Trianon Bonita Bay

Trianon Bonita Bay

3.5 out of 5
3401 Bay Commons Dr Bonita Springs FL
  • 20 min drive from Key West Express
Book a stay at this family-friendly hotel in Bonita Springs. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
9.2/10 Wonderful! (1,772 reviews)
We always book at the Trianon when we are in the area. The only thing I found wanting this visit was the mattress. It was hard and I don’t remember having this before

Reviewed on Apr 26, 2026

Trianon Bonita Bay
Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina

4 out of 5
275 Estero Blvd Fort Myers Beach FL
  • 7 min walk from Key West Express
Book a stay at this beach resort in Fort Myers Beach. Enjoy free breakfast, 3 outdoor pools, and 3 restaurants. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (1,330 reviews)
Wonderful stay overall. Breakfast buffet was tasty, staff was always attentive, abundant wait staff, beautiful views, adults only pool, and although a resort, didn’t feel penned in.

Reviewed on Apr 24, 2026

Pink Shell Beach Resort and Marina
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

4 out of 5
17260 Harbour Pointe Dr Fort Myers FL
  • 6 min drive from Key West Express
Book a stay at this spa resort in Fort Myers. Enjoy 3 outdoor pools, a full-service spa, and 4 restaurants. Our guests praise the helpful staff and the property ...
8.4/10 Very Good! (1,006 reviews)
Muy bonito lugar excelente todo

Reviewed on Apr 26, 2026

Marriott Sanibel Harbour Resort & Spa
Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers

3 out of 5
12600 University Dr Fort Myers FL
  • 17 min drive from Key West Express
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.8/10 Excellent! (1,004 reviews)
Perfect hotel!

Reviewed on Apr 27, 2026

Hilton Garden Inn Ft Myers
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

3 out of 5
20091 Summerlin Road Fort Myers FL
  • 6 min drive from Key West Express
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in ...
8.2/10 Very Good! (1,126 reviews)
Location

Reviewed on Apr 27, 2026

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
Holiday Inn Express & Suites Fort Myers Airport by IHG

Holiday Inn Express & Suites Fort Myers Airport by IHG

2.5 out of 5
14567 GLOBAL PARKWAY Fort Myers FL
  • 13 min drive from Key West Express
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.6/10 Exceptional! (1,009 reviews)
None at this time

Reviewed on Apr 27, 2026

Holiday Inn Express & Suites Fort Myers Airport by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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