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Mayo Clinic Florida Vacation Packages

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Mayo Clinic Florida Flight + Hotel Packages

Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront

3 out of 5
per person
May 24 - May 31
Roundtrip flight included
Newark (EWR) to Jacksonville (JAX)
Stay at this beach hotel in Jacksonville Beach. Enjoy free breakfast, a beach locale, and 2 bars/lounges. Our guests praise the breakfast and the pool in our reviews. Popular attractions Jacksonville Beach Pier and Mayport Naval Station are located nearby. Discover genuine guest reviews for Hampton Inn Jacksonville Beach/Oceanfront along with the latest prices and availability – book now.
Beachside Motel

Beachside Motel

2 out of 5
per person
May 27 - May 31
Roundtrip flight included
Newark (EWR) to Jacksonville (JAX)
Stay at this beach motel in Fernandina Beach. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Omni Amelia Island Resort Golf and Fernandina Beach are located nearby. Discover genuine guest reviews for Beachside Motel along with the latest prices and availability – book now.
Omni Amelia Island Resort

Omni Amelia Island Resort

4 out of 5
Save 100% on your flight
per person
Jun 7 - Jun 11
Roundtrip non-stop flight included
Newark (EWR) to Jacksonville (JAX)
Stay at this 4-star beach resort in Fernandina Beach. Enjoy free WiFi, 2 outdoor pools, and 9 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Omni Amelia Island Resort Golf and Amelia Island Nature Center are located nearby. Discover genuine guest reviews for Omni Amelia Island Resort along with the latest prices and availability – book now.
Ocean Coast Hotel at the Beach Amelia Island

Ocean Coast Hotel at the Beach Amelia Island

3 out of 5
per person
Jun 7 - Jun 11
Roundtrip non-stop flight included
Newark (EWR) to Jacksonville (JAX)
Stay at this 3-star business-friendly hotel in Fernandina Beach. Enjoy free WiFi, an outdoor pool, and a fitness center. Our guests praise the breakfast and the pool in our reviews. Popular attractions Omni Amelia Island Resort Golf and Seaside Park are located nearby. Discover genuine guest reviews for Ocean Coast Hotel at the Beach Amelia Island along with the latest prices and availability – book now.
Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

2.5 out of 5
per person
May 26 - Jun 2
Roundtrip non-stop flight included
Akron (CAK) to Jacksonville (JAX)
Stay at this beach hotel in Jacksonville Beach. Enjoy free WiFi, a beach locale, and breakfast. Our guests praise the pool and the bar in our reviews. Popular attractions Jacksonville Beach Pier and Mayport Naval Station are located nearby. Discover genuine guest reviews for Margaritaville Jacksonville Beach along with the latest prices and availability – book now.
Wyndham Garden Jacksonville

Wyndham Garden Jacksonville

3 out of 5
per person
May 24 - May 31
Roundtrip flight included
Newark (EWR) to Jacksonville (JAX)
Stay at this business-friendly hotel in Jacksonville. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions St. Johns Town Center and Jacksonville Naval Air Station are located nearby. Discover genuine guest reviews for Wyndham Garden Jacksonville, in Southside neighborhood, along with the latest prices and availability – book now.
Microtel Inn & Suites by Wyndham Jacksonville Airport

Microtel Inn & Suites by Wyndham Jacksonville Airport

2.5 out of 5
per person
May 24 - May 31
Roundtrip flight included
Newark (EWR) to Jacksonville (JAX)
Stay at this business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Jacksonville Zoo and Gardens and River City Market Place are located nearby. Discover genuine guest reviews for Microtel Inn & Suites by Wyndham Jacksonville Airport, in Northside neighborhood, along with the latest prices and availability – book now.
Aloft Jacksonville Tapestry Park

Aloft Jacksonville Tapestry Park

3 out of 5
per person
May 24 - May 31
Roundtrip flight included
Newark (EWR) to Jacksonville (JAX)
Stay at this 3-star family-friendly hotel in Jacksonville. Enjoy free WiFi, free parking, and breakfast. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions St. Johns Town Center and Dog Wood Park of Jacksonville are located nearby. Discover genuine guest reviews for Aloft Jacksonville Tapestry Park, in Southside neighborhood, along with the latest prices and availability – book now.
Weekly Inn

Weekly Inn

2 out of 5
per person
May 24 - May 31
Roundtrip flight included
Newark (EWR) to Jacksonville (JAX)
Stay at this motel in Jacksonville. Enjoy free WiFi, free parking, and a 24-hour business center. Popular attractions St. Johns Town Center and Jacksonville Cruise Terminal are located nearby. Discover genuine guest reviews for Weekly Inn, in Arlington neighborhood, along with the latest prices and availability – book now.
Holiday Inn Express Jacksonville South Bartram Prk, an IHG Hotel

Holiday Inn Express Jacksonville South Bartram Prk, an IHG Hotel

2.5 out of 5
per person
May 24 - May 31
Roundtrip flight included
Newark (EWR) to Jacksonville (JAX)
Stay at this business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Genovar Park and Falling Waters Pond are located nearby. Discover genuine guest reviews for Holiday Inn Express Jacksonville South Bartram Prk, an IHG Hotel, in Southside neighborhood, along with the latest prices and availability – book now.
Apm Inn and Suite

Apm Inn and Suite

2 out of 5
per person
May 24 - May 31
Roundtrip flight included
Newark (EWR) to Jacksonville (JAX)
Stay at this hotel in Jacksonville. Enjoy free WiFi, free parking, and breakfast. Popular attractions Gateway Shopping Center and Normandy Lane Plaza Shopping Center are located nearby. Discover genuine guest reviews for Apm Inn and Suite , in Northwest neighborhood, along with the latest prices and availability – book now.
Holiday Inn Express Jacksonville Beach, an IHG Hotel

Holiday Inn Express Jacksonville Beach, an IHG Hotel

2.5 out of 5
per person
May 24 - May 31
Roundtrip flight included
Newark (EWR) to Jacksonville (JAX)
Stay at this business-friendly hotel in Jacksonville Beach. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Jacksonville Beach Pier and Gonzales Park are located nearby. Discover genuine guest reviews for Holiday Inn Express Jacksonville Beach, an IHG Hotel along with the latest prices and availability – book now.
Prices and availability subject to change. Additional terms may apply.

3-4 Night Vacations in Mayo Clinic Florida

Tricove Inn & Suites

Tricove Inn & Suites

2.5 out of 5
Southside
per person
Jun 14 - Jun 17
Roundtrip flight included
Philadelphia (PHL) to Jacksonville (JAX)
Beachside Motel

Beachside Motel

2 out of 5
per person
May 27 - May 31
Roundtrip flight included
Newark (EWR) to Jacksonville (JAX)
The Villas of Amelia Island

The Villas of Amelia Island

4 out of 5
per person
May 27 - May 31
Roundtrip flight included
Newark (EWR) to Jacksonville (JAX)
Omni Amelia Island Resort

Omni Amelia Island Resort

4 out of 5
Save 100% on your flight
per person
Jun 7 - Jun 11
Roundtrip non-stop flight included
Newark (EWR) to Jacksonville (JAX)
Prices and availability subject to change. Additional terms may apply.

5-7 Night Vacations in Mayo Clinic Florida

Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront

3 out of 5
per person
May 24 - May 31
Roundtrip flight included
Newark (EWR) to Jacksonville (JAX)
Omni Amelia Island Resort

Omni Amelia Island Resort

4 out of 5
Save 100% on your flight
per person
May 31 - Jun 5
Roundtrip non-stop flight included
Newark (EWR) to Jacksonville (JAX)
Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

2.5 out of 5
per person
May 26 - Jun 2
Roundtrip non-stop flight included
Akron (CAK) to Jacksonville (JAX)
Wyndham Garden Jacksonville

Wyndham Garden Jacksonville

3 out of 5
Southside
per person
May 24 - May 31
Roundtrip flight included
Newark (EWR) to Jacksonville (JAX)
Prices and availability subject to change. Additional terms may apply.

Book the perfect getaway to Mayo Clinic Florida

With Hotwire, booking your next trip to Southside is a breeze. When it comes to planning a show-stopping vacay, you’re the reigning champion of doing it on a dime. You love to plan exciting destination adventures while saving money on a budget.

Hotwire is here to help you plan a smooth sailing trip to Mayo Clinic Florida while saving some major cash. Doubling up on vacation expenses like hotel and car rentals and fun-filled excursions can save you money—especially when you book one of Hotwire’s vacation packages.

If your trip to is spur-of-the-moment and you’re leaving soon, Hotwire can save you up to 60% off your rentals with Hotwire Hot Rate deals. Book with Hotwire to grab a stellar Mayo Clinic Florida flight and hotel package for as low as $332.

Living it up in Southside means getting there in style and staying in a hotel that matches your mood. Book one of Hotwire’s Mayo Clinic Florida, Southside vacation packages to enjoy the best of both worlds. Flight and hotel packages typically include roundtrip non-stop flights and multi-day hotel stays. Packages are priced per person and are perfect for flying solo or traveling with a group of friends or family. Conveniently choose from Hotwire’s inventory of hotels in Mayo Clinic Florida for some of the best accommodations and flight deals.

FAQs about cheap Mayo Clinic Florida packages:

How to get cheap vacation deals to Mayo Clinic Florida?

Save up to 60% off vacation deals with Hotwire Hot Rates. Just plug in your general preferences and let Hotwire choose matching hotels for as low as .

How much are Mayo Clinic Florida packages?

Vacation packages to Mayo Clinic Florida vary in price. They are priced per person and include discounted hotel and flight costs. With Hotwire, you can score a vacation package for as low as $332.

How to find cheap car rentals near Mayo Clinic Florida?

Hotwire partners with some of the most reliable car rental companies in Southside to bring you the best car rental deals in Mayo Clinic Florida for as low as . Select a rental from Hotwire’s extensive inventory of cars for every travel style. If you plan on bringing friends or family along, opt for a spacious SUV. If you’re visiting on business but still plan to make time for off-the-clock adventures, Hotwire offers sleek luxury and convertible rentals.

Is it safe to travel to Mayo Clinic Florida now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Mayo Clinic Florida right now?” When it’s time to book your vacation, check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.

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