Search Deals on
Mayo Clinic Florida Vacation Packages

Photo by Amber Palmer

Mayo Clinic Florida Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.
Southbank Hotel by Marriott Jacksonville Riverwalk

Southbank Hotel by Marriott Jacksonville Riverwalk

3.5 out of 5
Price was $408, price is now $309 per person
$309
per person
Jan 8 - Jan 12
found 5 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Jacksonville (JAX)
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions EverBank Stadium and Jacksonville Zoo and Gardens are located nearby.
Embassy Suites by Hilton Jacksonville Baymeadows

Embassy Suites by Hilton Jacksonville Baymeadows

3.5 out of 5
Price was $589, price is now $470 per person
$470
per person
Jan 25 - Jan 30
found 16 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Jacksonville (JAX)
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free breakfast, room service, and a 24-hour fitness center. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions St. Johns Town Center and Dog Wood Park of Jacksonville are located nearby.
Marble Waters Hotel & Suites, Trademark by Wyndham

Marble Waters Hotel & Suites, Trademark by Wyndham

3 out of 5
Price was $421, price is now $338 per person
$338
per person
Jan 25 - Jan 30
found 16 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Jacksonville (JAX)
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free WiFi, free parking, and a 24-hour fitness center. Popular attractions St. Johns Town Center and Wilson Center For the Arts are located nearby.
Homewood Suites by Hilton Jacksonville-South/St. Johns Ctr.

Homewood Suites by Hilton Jacksonville-South/St. Johns Ctr.

3 out of 5
Price was $576, price is now $474 per person
$474
per person
Jan 25 - Jan 30
found 16 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Jacksonville (JAX)
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions St. Johns Town Center and Topgolf are located nearby.
Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

2.5 out of 5
Save 100% on your flight
Price was $552, price is now $394 per person
$394
per person
Jan 8 - Jan 12
found 5 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Jacksonville (JAX)
Book a stay at this beach hotel in Jacksonville Beach. Enjoy free WiFi, a beach locale, and breakfast (surcharge). Our guests praise the pool and the helpful staff in our reviews. Popular attractions Jacksonville Beach Pier and Northeast Florida Beaches are located nearby.
The Villas of Amelia Island

The Villas of Amelia Island

4 out of 5
Save 100% on your flight
Price was $575, price is now $423 per person
$423
per person
Jan 8 - Jan 12
found 5 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Jacksonville (JAX)
Book a stay at this beach vacation home in Fernandina Beach. Enjoy free WiFi, 2 outdoor pools, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular attractions Amelia Island State Park and Fort George Island Cultural State Park are located nearby.
Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront

3 out of 5
Price was $560, price is now $421 per person
$421
per person
Jan 8 - Jan 12
found 5 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Jacksonville (JAX)
Book a stay at this beach hotel in Jacksonville Beach. Enjoy free breakfast, 2 outdoor pools, and a beach locale. Our guests praise the breakfast and the pool in our reviews. Popular attractions Sleiman North Shopping Center and Jacksonville Beach Pier are located nearby.
Courtyard by Marriott Jacksonville I-295/East Beltway

Courtyard by Marriott Jacksonville I-295/East Beltway

3 out of 5
Price was $483, price is now $366 per person
$366
per person
Jan 8 - Jan 12
found 5 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Jacksonville (JAX)
Stay at this hotel in Jacksonville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions St. Johns Town Center and EverBank Stadium are located nearby.
Ocean Coast Hotel at the Beach Amelia Island

Ocean Coast Hotel at the Beach Amelia Island

3 out of 5
Save 100% on your flight
Price was $787, price is now $597 per person
$597
per person
Jan 22 - Jan 26
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Jacksonville (JAX)
Book a stay at this business-friendly hotel in Fernandina Beach. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Seaside Park and Fernandina Beach Pinball Museum are located nearby.
Oceans of Amelia

Oceans of Amelia

2.5 out of 5
Save 100% on your flight
Price was $1,533, price is now $1,166 per person
$1,166
per person
Jan 8 - Jan 12
found 5 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Jacksonville (JAX)
Stay at this condo in Fernandina Beach. Enjoy free parking, laundry facilities, and concierge services. Popular attractions Fernandina Beach Main Beach Park and Egan's Creek Greenway Trail are located nearby.
Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic

4.5 out of 5
Save 100% on your flight
Price was $696, price is now $531 per person
$531
per person
Jan 8 - Jan 12
found 5 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Jacksonville (JAX)
Book a stay at this luxury hotel in Jacksonville. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions St. Johns Town Center and TPC Sawgrass are located nearby.
Florida House Inn

Florida House Inn

3 out of 5
Save 100% on your flight
Price was $645, price is now $498 per person
$498
per person
Jan 22 - Jan 26
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Jacksonville (JAX)
Stay at this B&B in Fernandina Beach. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Blue Door Artists and Island Art Association Gallery are located nearby.

3-4 Night Vacations in Mayo Clinic Florida

Price found within the past 48 hours. Click for updated prices.
Southbank Hotel by Marriott Jacksonville Riverwalk

Southbank Hotel by Marriott Jacksonville Riverwalk

3.5 out of 5
Downtown Jacksonville
Price was $408, price is now $309 per person
$309
per person
Jan 8 - Jan 12
found 5 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Jacksonville (JAX)
Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

2.5 out of 5
Save 100% on your flight
Price was $552, price is now $394 per person
$394
per person
Jan 8 - Jan 12
found 5 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Jacksonville (JAX)
The Villas of Amelia Island

The Villas of Amelia Island

4 out of 5
Save 100% on your flight
Price was $575, price is now $423 per person
$423
per person
Jan 8 - Jan 12
found 5 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Jacksonville (JAX)
Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront

3 out of 5
Price was $560, price is now $421 per person
$421
per person
Jan 8 - Jan 12
found 5 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Jacksonville (JAX)

5-7 Night Vacations in Mayo Clinic Florida

Price found within the past 48 hours. Click for updated prices.
Courtyard by Marriott Jacksonville I-295/East Beltway

Courtyard by Marriott Jacksonville I-295/East Beltway

3 out of 5
Arlington
Price was $555, price is now $439 per person
$439
per person
Jan 25 - Jan 30
found 16 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Jacksonville (JAX)
The Villas of Amelia Island

The Villas of Amelia Island

4 out of 5
Price was $695, price is now $528 per person
$528
per person
Jan 25 - Jan 30
found 16 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Jacksonville (JAX)
Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront

3 out of 5
Price was $708, price is now $548 per person
$548
per person
Jan 25 - Jan 30
found 16 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Jacksonville (JAX)
Embassy Suites by Hilton Jacksonville Baymeadows

Embassy Suites by Hilton Jacksonville Baymeadows

3.5 out of 5
Southside
Price was $589, price is now $470 per person
$470
per person
Jan 25 - Jan 30
found 16 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Jacksonville (JAX)

Mayo Clinic Florida Last Minute Hotel Deals

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic

4.5 out of 5
4745 Transformation Way Jacksonville FL
Book a stay at this luxury hotel in Jacksonville. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions St. Johns Town Center and TPC ...
Hilton Jacksonville At Mayo Clinic
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

3 out of 5
14390 Mayo Boulevard Jacksonville FL
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3 out of 5
4905 SAN PABLO ROAD SOUTH Jacksonville FL
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

2.5 out of 5
715 1st St N Jacksonville Beach FL
Book a stay at this beach hotel in Jacksonville Beach. Enjoy free WiFi, a beach locale, and breakfast (surcharge). Our guests praise the pool and the helpful ...
Margaritaville Jacksonville Beach
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

2.5 out of 5
4791 Windsor Commons Ct Jacksonville FL
Book a stay at this golf hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our ...
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

2.5 out of 5
13733 Beach Blvd Jacksonville FL
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East

3 out of 5
13741 BEACH BLVD Jacksonville FL
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
TownePlace Suites by Marriott Jacksonville East
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

2.5 out of 5
1220 Marsh Landing Pkwy Jacksonville Beach FL
Book a stay at this business-friendly hotel in Jacksonville Beach. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the ...
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
See all 1,852 properties in Mayo Clinic Florida
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover Other Travel Deals