Search Deals onMayo Clinic Florida Vacation Packages
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Mayo Clinic Florida Flight + Hotel Packages
Price found within the past 48 hours. Click for updated prices.

Vintage Amelia Island Apartments
Price was $336, price is now $296 per person
$296
per person
Dec 7 - Dec 11
found 3 hours ago
Roundtrip flight included
Boston (BOS) to Jacksonville (JAX)
Stay at this 3.5-star apartment in Fernandina Beach. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Fernandina Little Theatre and Egan's Creek Greenway Trail are located nearby.

Vista Verde Farm Retreat
Price was $887, price is now $782 per person
$782
per person
Dec 10 - Dec 17
found 9 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Jacksonville (JAX)
Stay at this hotel in Lake City. Enjoy free WiFi, free parking, and furnished balconies or patios. Popular attractions O'Leno State Park and Hog Lake are located nearby.

Hammock Beach Golf Resort & Spa
Save 100% on your flight
Price was $2,366, price is now $1,452 per person
$1,452
per person
Dec 6 - Dec 14
found 1 day ago
Roundtrip flight included
Boston (BOS) to Daytona Beach (DAB)
Stay at this 4-star luxury resort in Palm Coast. Enjoy free WiFi, free parking, and 9 outdoor pools. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Ocean Hammock Golf Club and Hammock Beach Ocean Course are located nearby.

Legacy Vacation Resorts Palm Coast
Save 100% on your flight
Price was $805, price is now $548 per person
$548
per person
Dec 6 - Dec 14
found 1 day ago
Roundtrip flight included
Boston (BOS) to Daytona Beach (DAB)
Stay at this 3-star family-friendly aparthotel in Palm Coast. Enjoy free parking, a fitness center, and daily housekeeping. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Palm Coast Resort Golf Club and Palm Harbor Golf Club are located nearby.

The Ritz-Carlton, Amelia Island
Save 100% on your flight
Price was $4,245, price is now $3,269 per person
$3,269
per person
Dec 29 - Jan 4
found 1 day ago
Roundtrip non-stop flight included
Richmond (RIC) to Jacksonville (JAX)
Stay at this 5-star luxury resort in Fernandina Beach. Enjoy a full-service spa, a beach locale, and a golf course. Our guests praise the property condition in our reviews. Popular attractions Peters Point Beachfront Park and Palmetto Walk Shopping Village are located nearby.

Holiday Inn Express & Suites Jacksonville Airport by IHG
Price was $538, price is now $422 per person
$422
per person
Dec 24 - Dec 28
found 12 hours ago
Roundtrip flight included
Atlanta (ATL) to Jacksonville (JAX)
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Jacksonville Zoo and Gardens and River City Market Place are located nearby.

Windsor Inn of Jacksonville
Price was $403, price is now $318 per person
$318
per person
Dec 24 - Dec 28
found 12 hours ago
Roundtrip flight included
Atlanta (ATL) to Jacksonville (JAX)
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Jacksonville Zoo and Gardens and River City Market Place are located nearby.

Fairfield Inn & Suites Jacksonville Airport
Price was $480, price is now $381 per person
$381
per person
Dec 24 - Dec 28
found 12 hours ago
Roundtrip flight included
Atlanta (ATL) to Jacksonville (JAX)
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Jacksonville Zoo and Gardens and River City Market Place are located nearby.

Marriott Jacksonville Downtown
Price was $547, price is now $445 per person
$445
per person
Dec 24 - Dec 28
found 12 hours ago
Roundtrip flight included
Atlanta (ATL) to Jacksonville (JAX)
Stay at this 4-star business-friendly hotel in Jacksonville. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions EverBank Stadium and Jacksonville Zoo and Gardens are located nearby.

King BED Hottub Palm Coast
Save 100% on your flight
Price was $1,256, price is now $1,024 per person
$1,024
per person
Dec 6 - Dec 14
found 1 day ago
Roundtrip flight included
Boston (BOS) to Daytona Beach (DAB)
Stay at this vacation home in Palm Coast. Enjoy free parking and a garden. Popular attractions Belle Terre Park and Grand Club Pine Lakes Golf Course are located nearby.

Noble Suites Jacksonville
Price was $413, price is now $345 per person
$345
per person
Dec 24 - Dec 28
found 12 hours ago
Roundtrip flight included
Atlanta (ATL) to Jacksonville (JAX)
Stay at this motel in Jacksonville. Enjoy free parking, daily housekeeping, and laundry facilities. Popular attractions Jacksonville Cruise Terminal and Jacksonville Zoo and Gardens are located nearby.

Comfort Suites Airport
Price was $519, price is now $435 per person
$435
per person
Dec 24 - Dec 28
found 12 hours ago
Roundtrip flight included
Atlanta (ATL) to Jacksonville (JAX)
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular attractions Jacksonville Zoo and Gardens and River City Market Place are located nearby.
3-4 Night Vacations in Mayo Clinic Florida
Price found within the past 48 hours. Click for updated prices.



5-7 Night Vacations in Mayo Clinic Florida
Price found within the past 48 hours. Click for updated prices.



Mayo Clinic Florida Last Minute Hotel Deals

Hilton Jacksonville At Mayo Clinic
4745 Transformation Way, Jacksonville, FL
Stay at this 4.5-star luxury hotel in Jacksonville. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions St. Johns Town Center and TPC ...

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
14390 Mayo Boulevard, Jacksonville, FL
Stay at this 3-star business-friendly hotel in Jacksonville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
4905 SAN PABLO ROAD SOUTH, Jacksonville, FL
Stay at this 3-star business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
4791 Windsor Commons Ct, Jacksonville, FL
Book a stay at this golf hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our ...

TownePlace Suites by Marriott Jacksonville East
13741 BEACH BLVD, Jacksonville, FL
Stay at this 3-star business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

Margaritaville Jacksonville Beach
715 1st St N, Jacksonville Beach, FL
Book a stay at this beach hotel in Jacksonville Beach. Enjoy free WiFi, a beach locale, and breakfast (surcharge). Our guests praise the pool and the bar in ...

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
13733 Beach Blvd, Jacksonville, FL
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
1220 Marsh Landing Pkwy, Jacksonville Beach, FL
Book a stay at this business-friendly hotel in Jacksonville Beach. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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