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Last Minute Hot Rate® Hotel Deals in Southeast Jacksonville

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Choose from 551 Southeast Jacksonville Hotel Deals

Midtown Lodge
Midtown Lodge
2.5 out of 5
4141 Philips Hwy, Jacksonville, FL
  • 14 min drive from Mayo Clinic Florida
The price is $61 per night from Jun 23 to Jun 24
$61
per night
Jun 23 - Jun 24
Stay at this motel in Jacksonville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions EverBank Stadium and VyStar Veterans Memorial ...
7.8/10 Good! (71 reviews)
"Thank you"

Reviewed on Jun 14, 2024

Midtown Lodge
Embassy Suites by Hilton Jacksonville Baymeadows
Embassy Suites by Hilton Jacksonville Baymeadows
3.5 out of 5
9300 Baymeadows Road, Jacksonville, FL
  • 11 min drive from Mayo Clinic Florida
The price is $106 per night from Jun 30 to Jul 1
$106
per night
Jun 30 - Jul 1
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free breakfast, free parking, and room service. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,001 reviews)
"We had a great overall experience! The breakfast was perfect!"

Reviewed on Jun 17, 2024

Embassy Suites by Hilton Jacksonville Baymeadows
Wyndham Garden Jacksonville
Wyndham Garden Jacksonville
3 out of 5
4660 Salisbury Road, I-95 Exit 344 (Butler Boulevard), Jacksonville, FL
  • 10 min drive from Mayo Clinic Florida
The price is $75 per night from Jun 27 to Jun 28
$75
per night
Jun 27 - Jun 28
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the ...
7/10 Good! (1,459 reviews)
"Second stay within a week. Rear entrance still out of service. Having to walk around building to front entrance was inconvenient, particularly in inclement weather. Because of previous stay, I know the rear entrance has remained unrepaired and inaccessible for substantial period."

Reviewed on Jun 20, 2024

Wyndham Garden Jacksonville
WaterWalk Jacksonville - Deerwood Park
WaterWalk Jacksonville - Deerwood Park
2 out of 5
8895 Perimeter Park Blvd, Jacksonville, FL
  • 8 min drive from Mayo Clinic Florida
The price is $119 per night from Jun 22 to Jun 23
$119
per night
Jun 22 - Jun 23
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free WiFi, free parking, and a 24-hour fitness center. Popular attractions St. Johns Town ...
9/10 Wonderful! (291 reviews)
"The rooms were very nice. They were extremely clean and quiet. The staff are fantastic!"

Reviewed on Jun 19, 2024

WaterWalk Jacksonville - Deerwood Park
Hyatt Place Jacksonville / St. Johns Town Center
Hyatt Place Jacksonville / St. Johns Town Center
3 out of 5
4742 Town Center Parkway, Jacksonville, FL
  • 6 min drive from Mayo Clinic Florida
The price is $121 per night from Jun 23 to Jun 24
$121
per night
Jun 23 - Jun 24
Stay at this 3-star business-friendly hotel in Jacksonville. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the breakfast ...
9.2/10 Wonderful! (1,041 reviews)
"Pool area has fantastic furnitur"

Reviewed on Jun 18, 2024

Hyatt Place Jacksonville / St. Johns Town Center
SpringHill Suites by Marriott Jacksonville Baymeadows
SpringHill Suites by Marriott Jacksonville Baymeadows
3 out of 5
9325 BAYMEADOWS ROAD, Jacksonville, FL
  • 11 min drive from Mayo Clinic Florida
The price is $93 per night from Jun 30 to Jul 1
$93
per night
Jun 30 - Jul 1
Stay at this 3-star business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the helpful staff and ...
9.2/10 Wonderful! (306 reviews)
"Very nice property Very clean Very nice and accommodating staff Very good dining options nearby"

Reviewed on Jun 16, 2024

SpringHill Suites by Marriott Jacksonville Baymeadows
Holiday Inn Express Jacksonville South Bartram Prk, an IHG Hotel
Holiday Inn Express Jacksonville South Bartram Prk, an IHG Hotel
2.5 out of 5
13934 VILLAGE LAKE CIRCLE, Jacksonville, FL
  • 22 min drive from Mayo Clinic Florida
The price is $100 per night from Jun 30 to Jul 1
$100
per night
Jun 30 - Jul 1
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (728 reviews)
"Breakfast was good"

Reviewed on Jun 15, 2024

Holiday Inn Express Jacksonville South Bartram Prk, an IHG Hotel
La Quinta Inn & Suites by Wyndham Jacksonville Butler Blvd
La Quinta Inn & Suites by Wyndham Jacksonville Butler Blvd
2.5 out of 5
4686 Lenoir Ave S, Jacksonville, FL
  • 11 min drive from Mayo Clinic Florida
The price is $74 per night from Jun 23 to Jun 24
$74
per night
Jun 23 - Jun 24
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
5.4/10 (1,146 reviews)
"Nice stay. Room is very clean"

Reviewed on Jun 9, 2024

La Quinta Inn & Suites by Wyndham Jacksonville Butler Blvd
Emerson Inn
Emerson Inn
2 out of 5
3558 Phillips Hwy, Jacksonville, FL
  • 14 min drive from Mayo Clinic Florida
The price is $69 per night from Jul 11 to Jul 12
$69
per night
Jul 11 - Jul 12
Stay at this motel in Jacksonville. Enjoy free WiFi, free parking, and 24-hour room service. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.8/10 Good! (1,000 reviews)
"Clean outside. Clean room. Desk staff could of been friendlier but wasnt too bad. Beds really need updated. When visiting jax i always stay here. It is updated nicely. Like i said beds need to be updated very hard. Blanket was to scrathcy for me. I will return anyway. Thank you for all you have done ..."

Reviewed on Jun 17, 2024

Emerson Inn
Sonesta Simply Suites Jacksonville
Sonesta Simply Suites Jacksonville
2.5 out of 5
4990 Belfort Rd, Jacksonville, FL
  • 10 min drive from Mayo Clinic Florida
The price is $86 per night from Jul 20 to Jul 21
$86
per night
Jul 20 - Jul 21
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the helpful staff ...
8.2/10 Very Good! (1,000 reviews)
"Good comfort, great bathroom"

Reviewed on Jun 10, 2024

Sonesta Simply Suites Jacksonville
Ramada Hotel & Conference Center by Wyndham Jacksonville
Ramada Hotel & Conference Center by Wyndham Jacksonville
3 out of 5
3130 Hartley Road, I-295 and San Jose, Jacksonville, FL
  • 18 min drive from Mayo Clinic Florida
The price is $80 per night from Jun 26 to Jun 27
$80
per night
Jun 26 - Jun 27
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the clean ...
6.4/10 (1,000 reviews)
"The pool wasn't operational. But they failed to let you know that during booking."

Reviewed on May 27, 2024

Ramada Hotel & Conference Center by Wyndham Jacksonville
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area, an IHG Hotel
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area, an IHG Hotel
2.5 out of 5
4791 Windsor Commons Ct, Jacksonville, FL
  • 20 min walk from Mayo Clinic Florida
The price is $125 per night from Jun 28 to Jun 29
$125
per night
Jun 28 - Jun 29
Book a stay at this golf hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our ...
8.2/10 Very Good! (1,006 reviews)
Very Near Mayos
"Right near Mayos Clinic, but much less expensive than other hotel chains near by. Also has a shuttle if you need it."

Reviewed on Jun 15, 2024

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area, an IHG Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Southeast Jacksonville

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Southeast Jacksonville hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Southeast Jacksonville.

Choosing the right hotel in Florida has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Southeast Jacksonville’s 551 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $61. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Southeast Jacksonville hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Southeast Jacksonville. No matter your reason for visiting Southeast Jacksonville, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Southeast Jacksonville hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Southeast Jacksonville for as low as $61.

How many hotels are there in Southeast Jacksonville?

With over 551 hotels in Southeast Jacksonville, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $61.

How to find cheap car rentals in Southeast Jacksonville?

Finding a cheap car rental deal in Southeast Jacksonville is as easy as scoring cheap hotels in Southeast Jacksonville. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Southeast Jacksonville now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Southeast Jacksonville right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.